Click here to switch to the map view.

The map label for this gene is infC

Identifier: 170755251

GI number: 170755251

Start: 3397649

End: 3398203

Strand: Reverse

Name: infC

Synonym: CLD_1404

Alternate gene names: 170755251

Gene position: 3398203-3397649 (Counterclockwise)

Preceding gene: 170754255

Following gene: 170756486

Centisome position: 85.85

GC content: 31.17

Gene sequence:

>555_bases
TTGTTAAGTGTTTTCGGTCTAATATTTTTGGAGGTGAAGATTATTAACAAAAACTATCTTATGAATGAGCAAATCCGTGA
AAAAGAAGTAAGACTTGTAGGTAGCGAGGGAGAACAATTAGGAGTAGTGTCTTCAAGTGAGGCGCAAAAGCTTGCAGATG
AAAAGGAACTAGACTTAGTACTTATAGCTCCAACTGCAAAACCACCAGTTTGTAAAATAATGAATCATGGTAAATTCTTA
TATGAACAAACTAAAAAAGATAAAGAAGCTAAAAAGAATCAAAAGGTTATAAACATAAAAGAAGTTAGACTAAGTCCAAC
TATAGAAGCACATGACATAGAAATTAAAGCTAACAATGCTAGAAAATTTTTAAATGCAGGAAATAAAGTTAAAGTAACTG
TTAGATTCAGAGGTAGAGAAGCTGATTATTCCTTTAAAGGAAATAAAATATTAAATTCCTTTTATGAAAAAGTTGAAGAA
GCCGGTGTTATGGAAAAAGCACCTAAACTAGAAGGAAGAAATATGATAATGATATTAGCGCCAAGAAAAGCGTAA

Upstream 100 bases:

>100_bases
ACCTTACAGCATGGCTAGTAAGGTTAGAGTATATGAATTTAATTTATATTATTGTTTATGAAGACGGCTTATGCCGTCTT
TTATTTATTATACATGAAAA

Downstream 100 bases:

>100_bases
TAACGAGGGGAGGAAATCACAATGCCAAAAATGAAAACAAAAAGGGCTGCAGCAAAGAGATTTAAAGTAACTGGAACAGG
TAAATTAAAGAGAGCTAAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MLSVFGLIFLEVKIINKNYLMNEQIREKEVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNHGKFL
YEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILNSFYEKVEE
AGVMEKAPKLEGRNMIMILAPRKA

Sequences:

>Translated_184_residues
MLSVFGLIFLEVKIINKNYLMNEQIREKEVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNHGKFL
YEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILNSFYEKVEE
AGVMEKAPKLEGRNMIMILAPRKA
>Mature_184_residues
MLSVFGLIFLEVKIINKNYLMNEQIREKEVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNHGKFL
YEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILNSFYEKVEE
AGVMEKAPKLEGRNMIMILAPRKA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=50, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20889; Mature: 20889

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVFGLIFLEVKIINKNYLMNEQIREKEVRLVGSEGEQLGVVSSSEAQKLADEKELDLV
CCHHHEEEEEEEEEECCCCEECHHHHHCEEEEECCCCCEEEEEECCHHHHHCCCCCCCEE
LIAPTAKPPVCKIMNHGKFLYEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNA
EEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEEEECCH
RKFLNAGNKVKVTVRFRGREADYSFKGNKILNSFYEKVEEAGVMEKAPKLEGRNMIMILA
HHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEE
PRKA
CCCC
>Mature Secondary Structure
MLSVFGLIFLEVKIINKNYLMNEQIREKEVRLVGSEGEQLGVVSSSEAQKLADEKELDLV
CCHHHEEEEEEEEEECCCCEECHHHHHCEEEEECCCCCEEEEEECCHHHHHCCCCCCCEE
LIAPTAKPPVCKIMNHGKFLYEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNA
EEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEEEECCH
RKFLNAGNKVKVTVRFRGREADYSFKGNKILNSFYEKVEEAGVMEKAPKLEGRNMIMILA
HHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEE
PRKA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]