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The map label for this gene is ispH [H]

Identifier: 170754879

GI number: 170754879

Start: 1926527

End: 1928443

Strand: Reverse

Name: ispH [H]

Synonym: CLD_2833

Alternate gene names: 170754879

Gene position: 1928443-1926527 (Counterclockwise)

Preceding gene: 170755162

Following gene: 170757228

Centisome position: 48.72

GC content: 27.91

Gene sequence:

>1917_bases
ATGAATGTAATTTTAGCAGATAAAGCAGGGTTTTGCTTTGGTGTTAAAAGAGCTTTAGATACAACAATAAATACCAAAGA
AAATTTAAAGAGTAAAATTTATACTTTAGGTCCTTTGATACATAATAATGATGTGGTTAATCTTTTAAAAGACAAAGGTA
TAGAACCTATAAGTATACAGGATGTAGATAAACTTAACAAAGATGATACTATTATTATAAGATCTCATGGAGTACCACTT
CAAACTATAAACTATTTAAAAGACAAAGGGTTAAATGTTATAAATACAACCTGCCCTCATGTGGCCAATATACAAATTAA
AGCTAAAAAATATTATGAAGAAGGTTACAAAATAGTAATAGTTGGAGATGAAAATCATCCAGAGGTTATTGGGATAAATG
GTTGGTGTAATAATTCTGCTATTATCTCAAAGGATGGTGCCAATATAAATAACTTAGATAAAAAAGTTTGCGTATTGTGT
CAAACCACAGAAAAACAAGAAAATTGGGAAAAGGTCCTTACTATATTAATTAAAAACTCTAGAGAAATATTAGCTTTTAA
TACTATATGTAATGCAACACAAGTGCGCCAACAAGCTGCAAAAAAATTATCTGAAAAAGTGGATAGCATGATAGTTATAG
GTGGTAAAAATAGTTCTAATACTACTAAGCTTTATGAAATATGTAAAAGTAATTGCAAAAATACAATACATGTTGAAAAT
GCAAAGGAAATACCTGAGCACATATATAAAAACTCAAATATTATAGGCGTTACTGCCGGAGCATCTACACCAGATTGGAT
TATAAAGGAGGCTATTAATAAAATGAATAATAATGATAGTATAATAGAAGTATCAAAAAATGAAATGCTTAACTATATGA
ACGAAAAGGAGCAACAAATAGTAGTTGGAAAAGTAGTAAAAGGAACTATAGTTTCTTTAAATGAAAATGAGTTATTTGTT
GATTTAAACTATAAATCTGAAGGCATTATACCTAAAGAAGAAGTAACTTTAGATGAAGAATCTATATTAAAAGAATCCTT
TAAGGTAGGAGATGAAATAGAAGCCAAAATAGTTAGAATAAAAAATGAAGATGGATACGTGGTACTATCCTTAAAGGAAT
TGCATCGTGAAAAAGCCTTAAAAAATTTAAAAGAAGCCTTTGAAAATAAACAAACTATAAAAGTTATTGTAAAAGATGCC
GTTGATGCTGGATTAATATGTATATATAATGGTGTTAGAGTATTTATTCCAGCTTCTCATATAGAACTTTCCCATGTAGA
TGACTTAGAGGCATATAAAGGCTTAGAATTAGAAGTTAATATCATTGAATTTATAAAAGATAGGTATAGAACTAAAATAG
TAGGTTCAAGAAGAAACATATTAAAAACTGTTAGAAATAAACATATAGAAGAAACTTGGAACTCTTTAGAAAAAGATACA
GTAGTAGAAGGAGAAGTAAAAAGATTCACAGACTTTGGAGCTTTTATAGAAATTAACGGAGTGGATGGTTTACTACATGT
TTCAGAAATATCCTGGGGAAGAGTAGAAAAGCCAGAAGATGCATTAAAAATAGGAAATAAAATAAAAGTATATATTTTAG
ATATTGATAAGGAAAATAAAAAACTAGCTTTAAGCATAAAAAAATTAATAGAAGATCCTTGGAAAAGTGTAGAGATAAAA
TATCCAATAGGAAATATAGTATTAGGAAAAGTAGTTAGATTTGCAAACTTTGGAGCTTTTATAGAATTAGAACCTGGTGT
AGATGGCCTAGTGCATATATCAAAAATAAGCAATAAAAGAATAGATAAACCAGAAGAAGAGTTAACTTTAGGAAAAGAAG
TCAAAGCTAAAATACTAGAAGTTAATTCAGTTGAAAAAAGAATTGCATTAAGTATAAAAGACGTTGAAGAATTTTAA

Upstream 100 bases:

>100_bases
AGTTGATAAAATATGTAACATAATAAAAAAGGATTAAGAAATAATCATGAATCCTATAAAAAAAGCAATATTAAAACTAA
TGAAGTTAGGAGAATAGAAG

Downstream 100 bases:

>100_bases
TATTGTTTAAAGATTTATTTTTAAAATCAATATTATTTAAAATTATAATTTAAATGTATAAAGTATATGTATTAGATGAA
AATATTAATACATATATTTT

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MNVILADKAGFCFGVKRALDTTINTKENLKSKIYTLGPLIHNNDVVNLLKDKGIEPISIQDVDKLNKDDTIIIRSHGVPL
QTINYLKDKGLNVINTTCPHVANIQIKAKKYYEEGYKIVIVGDENHPEVIGINGWCNNSAIISKDGANINNLDKKVCVLC
QTTEKQENWEKVLTILIKNSREILAFNTICNATQVRQQAAKKLSEKVDSMIVIGGKNSSNTTKLYEICKSNCKNTIHVEN
AKEIPEHIYKNSNIIGVTAGASTPDWIIKEAINKMNNNDSIIEVSKNEMLNYMNEKEQQIVVGKVVKGTIVSLNENELFV
DLNYKSEGIIPKEEVTLDEESILKESFKVGDEIEAKIVRIKNEDGYVVLSLKELHREKALKNLKEAFENKQTIKVIVKDA
VDAGLICIYNGVRVFIPASHIELSHVDDLEAYKGLELEVNIIEFIKDRYRTKIVGSRRNILKTVRNKHIEETWNSLEKDT
VVEGEVKRFTDFGAFIEINGVDGLLHVSEISWGRVEKPEDALKIGNKIKVYILDIDKENKKLALSIKKLIEDPWKSVEIK
YPIGNIVLGKVVRFANFGAFIELEPGVDGLVHISKISNKRIDKPEEELTLGKEVKAKILEVNSVEKRIALSIKDVEEF

Sequences:

>Translated_638_residues
MNVILADKAGFCFGVKRALDTTINTKENLKSKIYTLGPLIHNNDVVNLLKDKGIEPISIQDVDKLNKDDTIIIRSHGVPL
QTINYLKDKGLNVINTTCPHVANIQIKAKKYYEEGYKIVIVGDENHPEVIGINGWCNNSAIISKDGANINNLDKKVCVLC
QTTEKQENWEKVLTILIKNSREILAFNTICNATQVRQQAAKKLSEKVDSMIVIGGKNSSNTTKLYEICKSNCKNTIHVEN
AKEIPEHIYKNSNIIGVTAGASTPDWIIKEAINKMNNNDSIIEVSKNEMLNYMNEKEQQIVVGKVVKGTIVSLNENELFV
DLNYKSEGIIPKEEVTLDEESILKESFKVGDEIEAKIVRIKNEDGYVVLSLKELHREKALKNLKEAFENKQTIKVIVKDA
VDAGLICIYNGVRVFIPASHIELSHVDDLEAYKGLELEVNIIEFIKDRYRTKIVGSRRNILKTVRNKHIEETWNSLEKDT
VVEGEVKRFTDFGAFIEINGVDGLLHVSEISWGRVEKPEDALKIGNKIKVYILDIDKENKKLALSIKKLIEDPWKSVEIK
YPIGNIVLGKVVRFANFGAFIELEPGVDGLVHISKISNKRIDKPEEELTLGKEVKAKILEVNSVEKRIALSIKDVEEF
>Mature_638_residues
MNVILADKAGFCFGVKRALDTTINTKENLKSKIYTLGPLIHNNDVVNLLKDKGIEPISIQDVDKLNKDDTIIIRSHGVPL
QTINYLKDKGLNVINTTCPHVANIQIKAKKYYEEGYKIVIVGDENHPEVIGINGWCNNSAIISKDGANINNLDKKVCVLC
QTTEKQENWEKVLTILIKNSREILAFNTICNATQVRQQAAKKLSEKVDSMIVIGGKNSSNTTKLYEICKSNCKNTIHVEN
AKEIPEHIYKNSNIIGVTAGASTPDWIIKEAINKMNNNDSIIEVSKNEMLNYMNEKEQQIVVGKVVKGTIVSLNENELFV
DLNYKSEGIIPKEEVTLDEESILKESFKVGDEIEAKIVRIKNEDGYVVLSLKELHREKALKNLKEAFENKQTIKVIVKDA
VDAGLICIYNGVRVFIPASHIELSHVDDLEAYKGLELEVNIIEFIKDRYRTKIVGSRRNILKTVRNKHIEETWNSLEKDT
VVEGEVKRFTDFGAFIEINGVDGLLHVSEISWGRVEKPEDALKIGNKIKVYILDIDKENKKLALSIKKLIEDPWKSVEIK
YPIGNIVLGKVVRFANFGAFIELEPGVDGLVHISKISNKRIDKPEEELTLGKEVKAKILEVNSVEKRIALSIKDVEEF

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0539

COG function: function code J; Ribosomal protein S1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 S1 motif domains [H]

Homologues:

Organism=Escherichia coli, GI1787140, Length=340, Percent_Identity=32.0588235294118, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1786212, Length=287, Percent_Identity=29.9651567944251, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI145693187, Length=75, Percent_Identity=46.6666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082262, Length=98, Percent_Identity=39.7959183673469, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323885, Length=255, Percent_Identity=23.5294117647059, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: 16,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR000110
- InterPro:   IPR022967 [H]

Pfam domain/function: PF02401 LYTB; PF00575 S1 [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 71920; Mature: 71920

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVILADKAGFCFGVKRALDTTINTKENLKSKIYTLGPLIHNNDVVNLLKDKGIEPISIQ
CCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHEEECCEEECCCHHHHHHHCCCCCCCCC
DVDKLNKDDTIIIRSHGVPLQTINYLKDKGLNVINTTCPHVANIQIKAKKYYEEGYKIVI
CHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEHHHCCCEEEE
VGDENHPEVIGINGWCNNSAIISKDGANINNLDKKVCVLCQTTEKQENWEKVLTILIKNS
EECCCCCCEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCC
REILAFNTICNATQVRQQAAKKLSEKVDSMIVIGGKNSSNTTKLYEICKSNCKNTIHVEN
CEEEEEEHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECC
AKEIPEHIYKNSNIIGVTAGASTPDWIIKEAINKMNNNDSIIEVSKNEMLNYMNEKEQQI
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCHHHEE
VVGKVVKGTIVSLNENELFVDLNYKSEGIIPKEEVTLDEESILKESFKVGDEIEAKIVRI
EEEEEEECEEEEECCCEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCEEEEEEE
KNEDGYVVLSLKELHREKALKNLKEAFENKQTIKVIVKDAVDAGLICIYNGVRVFIPASH
ECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCEEEEEEECC
IELSHVDDLEAYKGLELEVNIIEFIKDRYRTKIVGSRRNILKTVRNKHIEETWNSLEKDT
EEECCCCCHHHHCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
VVEGEVKRFTDFGAFIEINGVDGLLHVSEISWGRVEKPEDALKIGNKIKVYILDIDKENK
CCCCHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCHHHHHCCCEEEEEEEEECCCCC
KLALSIKKLIEDPWKSVEIKYPIGNIVLGKVVRFANFGAFIELEPGVDGLVHISKISNKR
CHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEHHCCCC
IDKPEEELTLGKEVKAKILEVNSVEKRIALSIKDVEEF
CCCCHHHHHCCHHHHHHHEECCCCCHHHEEEEHHHHCC
>Mature Secondary Structure
MNVILADKAGFCFGVKRALDTTINTKENLKSKIYTLGPLIHNNDVVNLLKDKGIEPISIQ
CCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHEEECCEEECCCHHHHHHHCCCCCCCCC
DVDKLNKDDTIIIRSHGVPLQTINYLKDKGLNVINTTCPHVANIQIKAKKYYEEGYKIVI
CHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEHHHCCCEEEE
VGDENHPEVIGINGWCNNSAIISKDGANINNLDKKVCVLCQTTEKQENWEKVLTILIKNS
EECCCCCCEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCC
REILAFNTICNATQVRQQAAKKLSEKVDSMIVIGGKNSSNTTKLYEICKSNCKNTIHVEN
CEEEEEEHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECC
AKEIPEHIYKNSNIIGVTAGASTPDWIIKEAINKMNNNDSIIEVSKNEMLNYMNEKEQQI
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCHHHEE
VVGKVVKGTIVSLNENELFVDLNYKSEGIIPKEEVTLDEESILKESFKVGDEIEAKIVRI
EEEEEEECEEEEECCCEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCEEEEEEE
KNEDGYVVLSLKELHREKALKNLKEAFENKQTIKVIVKDAVDAGLICIYNGVRVFIPASH
ECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCEEEEEEECC
IELSHVDDLEAYKGLELEVNIIEFIKDRYRTKIVGSRRNILKTVRNKHIEETWNSLEKDT
EEECCCCCHHHHCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
VVEGEVKRFTDFGAFIEINGVDGLLHVSEISWGRVEKPEDALKIGNKIKVYILDIDKENK
CCCCHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCHHHHHCCCEEEEEEEEECCCCC
KLALSIKKLIEDPWKSVEIKYPIGNIVLGKVVRFANFGAFIELEPGVDGLVHISKISNKR
CHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEHHCCCC
IDKPEEELTLGKEVKAKILEVNSVEKRIALSIKDVEEF
CCCCHHHHHCCHHHHHHHEECCCCCHHHEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]