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The map label for this gene is xdhB [H]

Identifier: 170754833

GI number: 170754833

Start: 1414662

End: 1415546

Strand: Direct

Name: xdhB [H]

Synonym: CLD_3282

Alternate gene names: 170754833

Gene position: 1414662-1415546 (Clockwise)

Preceding gene: 170755646

Following gene: 170754477

Centisome position: 35.74

GC content: 28.25

Gene sequence:

>885_bases
ATGTATGATATAAATGAAATTTTAGAACCTAAAACATTAGAAAAGGCATTAGAATTATTATCAGAACACGATAATTTAAC
GGTAATAGCTGGAGGAACTGATGTACTTGTAAAACTTCATGAAGAAAGATTTAATTCTTTAAATTTAATAAGTATTAGAA
ACATAGAGAGTTTAAATGAAATAAAAGTAATTGAGAATGGCTCAATAGAAATAGGTGCTATGGCAACTTTTTCAGAAATA
TTTAGGGATGATATAGTAAATAAAAATATTCCTATACTAGCAGAAGCAGCAGTTTCTATGGGAGGACCTCAAATTAGAAA
TATGGCAACCATTGGAGGAAATATTTGTAATGGAGCTGTATCCGGAGATAGTGCACCATCATTATTTGCATTAAATAGTA
AATTAAGACTTAAATCTAAAAATGGTGAGAGAATAGTTAAAATAAAAGATTTTTATATAGGCCCTGGACAGGTTGGCATC
AGAAAAGATGAGATATTAATTAGTATAATTATTGAAAAAAAAGATTATGAAAATAAGTATGGTAATTATATTAAATTTGC
TAGTAGAAATGCAATGGACATAGCTTTAATGGGAGTTGCTGTACTTGTAGAAGTTAAGAATAAAAAGTTTGAAGATTTAA
GAATAGCGTTAGGTGTATCAGGTCCAACACCTATAAGATGTGAAATAGCTGAAGCAGAGGGAAAACATATGAAAGTTACG
GATGAAAATATAAGATTAATAGGAAATTTAGCTCTGAAATCTTCAAAAGCAATAGATTTTTGGAATGCATCAAAGGAATT
TAAAGAGCATTTAATACAAGAATTAACTTATAGAGGACTTAATGAATCTGTTAAAAGAGCAGAAAATTTTGAAAATATAA
AGTAA

Upstream 100 bases:

>100_bases
TTGAATGCAACAGGAGTAGCATTTAATAAATTACCAATGGATGCTCAATCTGTTTTTGAGAAATTTAAAGAGGTTGGACT
TATATAGGAGGCGAAATAAT

Downstream 100 bases:

>100_bases
TAGGATACAGTTAGGGGGATGATGAATATATATGAGTTTAAAAAGAAAAATAAAATTTACAGTTAATGATAAAAAGTATG
AAGTAGAAATAGATATTAGA

Product: xanthine dehydrogenase subunit XdhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNEIKVIENGSIEIGAMATFSEI
FRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAVSGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVGI
RKDEILISIIIEKKDYENKYGNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLNESVKRAENFENIK

Sequences:

>Translated_294_residues
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNEIKVIENGSIEIGAMATFSEI
FRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAVSGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVGI
RKDEILISIIIEKKDYENKYGNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLNESVKRAENFENIK
>Mature_294_residues
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNEIKVIENGSIEIGAMATFSEI
FRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAVSGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVGI
RKDEILISIIIEKKDYENKYGNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLNESVKRAENFENIK

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=287, Percent_Identity=38.6759581881533, Blast_Score=232, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17540638, Length=228, Percent_Identity=27.1929824561404, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17737937, Length=234, Percent_Identity=29.4871794871795, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 32675; Mature: 32675

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNE
CCCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHCCCEEEEEECCCCCCCE
IKVIENGSIEIGAMATFSEIFRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAV
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHCCCCCCCCCCC
SGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVGIRKDEILISIIIEKKDYENKY
CCCCCCCEEEECCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCC
GNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
CCEEEECCCCCHHHHHHHEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEE
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLNESVKRAENFENIK
CCCEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNE
CCCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHCCCEEEEEECCCCCCCE
IKVIENGSIEIGAMATFSEIFRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAV
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHCCCCCCCCCCC
SGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVGIRKDEILISIIIEKKDYENKY
CCCCCCCEEEECCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCC
GNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
CCEEEECCCCCHHHHHHHEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEE
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLNESVKRAENFENIK
CCCEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]