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The map label for this gene is xdhC [H]

Identifier: 170754477

GI number: 170754477

Start: 1415578

End: 1416051

Strand: Direct

Name: xdhC [H]

Synonym: CLD_3281

Alternate gene names: 170754477

Gene position: 1415578-1416051 (Clockwise)

Preceding gene: 170754833

Following gene: 170757063

Centisome position: 35.76

GC content: 31.01

Gene sequence:

>474_bases
ATGAGTTTAAAAAGAAAAATAAAATTTACAGTTAATGATAAAAAGTATGAAGTAGAAATAGATATTAGAGAATCTTTATC
AGAAGTGTTAAGAAGTAGATTACATTTAACAGGTGTTAAACAAGGATGTCTTGTAGGAGAATGTGGAGCATGTACTGTCT
TAATAGATGGTGTCCCAACAGACTCATGTATTTACTTAGCGGCTTGGGCTGATGGTAAAACAATAAAAACTATTGAGGGG
GTACAAAAAAATGGTGAGCTTTCAGAGGTTCAAAAAGCCTTTATAGATGAAGGTGCTGTACAATGTGGATTCTGTACACC
GGGTTTAGTTTTAACTACAACAGCTTTAGTAGAAAGCGAAAAAAACTATACTGATGATGAAATAAAAAGAGAAATATCAG
GTCATTTATGTAGATGTACTGGATATAATAAAATATTTAATGCTACCAAAAAAGCCATTTTAAAAAGAAAATAG

Upstream 100 bases:

>100_bases
CAAGAATTAACTTATAGAGGACTTAATGAATCTGTTAAAAGAGCAGAAAATTTTGAAAATATAAAGTAATAGGATACAGT
TAGGGGGATGATGAATATAT

Downstream 100 bases:

>100_bases
TATTTAGGTTTATAATATGATAATCACTACAAGGTAAGTTTTGACAAGATTATTTTTAAAGTATAATATTAAGATATATA
GTTTAATTATTAAATGATTT

Product: xanthine dehydrogenase family protein, iron-sulfur binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEG
VQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK

Sequences:

>Translated_157_residues
MSLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEG
VQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
>Mature_156_residues
SLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEGV
QKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=162, Percent_Identity=30.2469135802469, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=33.1210191082803, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=55.2447552447552, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=37.037037037037, Blast_Score=115, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=152, Percent_Identity=39.4736842105263, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.6623376623377, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=33.9869281045752, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737937, Length=154, Percent_Identity=35.0649350649351, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=34.375, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=34.375, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=35.5263157894737, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=35.4838709677419, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=29.746835443038, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 17349; Mature: 17218

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPT
CCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DSCIYLAAWADGKTIKTIEGVQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESE
CCEEEEEEECCCCEEHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
KNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
CCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPT
CCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DSCIYLAAWADGKTIKTIEGVQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESE
CCEEEEEEECCCCEEHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
KNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
CCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]