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The map label for this gene is bdhA [H]

Identifier: 170754748

GI number: 170754748

Start: 1573196

End: 1574359

Strand: Direct

Name: bdhA [H]

Synonym: CLD_3130

Alternate gene names: 170754748

Gene position: 1573196-1574359 (Clockwise)

Preceding gene: 170757778

Following gene: 170755995

Centisome position: 39.74

GC content: 31.1

Gene sequence:

>1164_bases
ATGCTAAATTTTAATTATTCTATACCAACAAAAATTTTTTTTGGTAAAAACCAAATAAATGTTTTAGGAGAGCAAATAAA
AAAATATGGATCAAGGGTATTGCTTACTTATGGTGGAGGAAGTATAAAAAAGAATGGAATATATGATAAAGTTATAAAAA
TTTTAAAGAGCAATAATATAGAATTTGTTGAGCTTTCAGGAATAGATCCTAATCCAAGAGTAACTAGTGTAAGGGAAGGA
GTAAAATTATGCAAAGAAAATAATATAGATTTCATATTAGCAGTAGGAGGAGGAAGTACTATAGATTGCTCAAAGGTAAT
AGCTGCATCATATTATTATGAAGGAGATCCTTGGGATATAGTAACTAAAAAAGTTAAAATAAATAAGGCATTACCTATAG
GAAGTATATTAACACTAGCTGCCACTGGCTCAGAAATGGATGCTGGAGCAGTAATTAGTAATATGGATACTAATGAGAAA
ATAGGAGTAGGACATCCTTCCATGGCCCCTAAATTTTCCATACTAGATCCAGAATATACTTTTACAGTGCCTAAAAATCA
AACAGCAGCAGGAACTGCAGATATAATGAGTCATATATTTGAAGCCTATTTCAGTAAGACAAAGGAAGCTTATATTCAAA
ATAGAATGGCAGAGGCTATTTTAAAAACTTGTATAAAGTATGGGAAAGTAGCTATAAAGGAGCCAGAAAATTATGAAGCT
AGGGCTAACCTTATGTGGGCATCTAGCTTAGCTATAAATGGATTATTAAGTTATGGTAAATCAGAACCTTGGAGTGTACA
CCCTATGGAACATGAATTGAGTGCTTTTTATGATATAACTCATGGTGTGGGGTTAGCTATATTAACGCCAAATTGGATGA
AATATGTTTTGAGCGATGAAAATGTAAATGATTTTTATGAATATGGAGTAAATGTTTGGGATATAAATCCAGAAGAAAGC
AAATATGAAGTAGCACAAAAGGCTATAGAAAAAACTCGAGAATATTTTATAGAATTAGGAATTCCAGCCACATTAAAAGA
AGTAGGTATAGAAGAAGAAAAACTAGAACAAATGGCAGAGGCTGCTACAAGAAATGGAACTTTAGATGGTTTTAAACCTT
TAAGTACTGAAGATGTTTTAAATATATATAAATTATCACTTTAA

Upstream 100 bases:

>100_bases
GTTTTAGGTAATGACATAGAGACACAAGTGATGTTGTAGTATATGCTTTCAAACTATTTCTTAAAATAATATTTAATTAA
AGATAATGGGAGGAGAAATA

Downstream 100 bases:

>100_bases
CTTTAATATAAAATATATACCTATGTTAGGTGATTCTTGATTTTAAATATAGTTTCATTAGAAATAATTATCATTGAAAT
TTAAAATTATTTATTTAAGA

Product: NADH-dependent butanol dehydrogenase

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLNFNYSIPTKIFFGKNQINVLGEQIKKYGSRVLLTYGGGSIKKNGIYDKVIKILKSNNIEFVELSGIDPNPRVTSVREG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDENVNDFYEYGVNVWDINPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIEEEKLEQMAEAATRNGTLDGFKPLSTEDVLNIYKLSL

Sequences:

>Translated_387_residues
MLNFNYSIPTKIFFGKNQINVLGEQIKKYGSRVLLTYGGGSIKKNGIYDKVIKILKSNNIEFVELSGIDPNPRVTSVREG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDENVNDFYEYGVNVWDINPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIEEEKLEQMAEAATRNGTLDGFKPLSTEDVLNIYKLSL
>Mature_387_residues
MLNFNYSIPTKIFFGKNQINVLGEQIKKYGSRVLLTYGGGSIKKNGIYDKVIKILKSNNIEFVELSGIDPNPRVTSVREG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDENVNDFYEYGVNVWDINPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIEEEKLEQMAEAATRNGTLDGFKPLSTEDVLNIYKLSL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=423, Percent_Identity=21.2765957446809, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789386, Length=355, Percent_Identity=43.943661971831, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI48994951, Length=393, Percent_Identity=28.498727735369, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=25.5874673629243, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787493, Length=376, Percent_Identity=23.936170212766, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082107, Length=388, Percent_Identity=24.2268041237113, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=395, Percent_Identity=24.5569620253165, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321181, Length=366, Percent_Identity=27.5956284153005, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 43000; Mature: 43000

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFNYSIPTKIFFGKNQINVLGEQIKKYGSRVLLTYGGGSIKKNGIYDKVIKILKSNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
EFVELSGIDPNPRVTSVREGVKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDI
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCHHH
VTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEKIGVGHPSMAPKFSILDPEYT
EEEEEEECCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEE
FTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCH
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDE
HEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCHHHEEEECCC
NVNDFYEYGVNVWDINPEESKYEVAQKAIEKTREYFIELGIPATLKEVGIEEEKLEQMAE
CCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCHHHHHHHHH
AATRNGTLDGFKPLSTEDVLNIYKLSL
HHHCCCCCCCCCCCCHHHHHHHHEECC
>Mature Secondary Structure
MLNFNYSIPTKIFFGKNQINVLGEQIKKYGSRVLLTYGGGSIKKNGIYDKVIKILKSNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
EFVELSGIDPNPRVTSVREGVKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDI
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCHHH
VTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEKIGVGHPSMAPKFSILDPEYT
EEEEEEECCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEE
FTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCH
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDE
HEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCHHHEEEECCC
NVNDFYEYGVNVWDINPEESKYEVAQKAIEKTREYFIELGIPATLKEVGIEEEKLEQMAE
CCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCHHHHHHHHH
AATRNGTLDGFKPLSTEDVLNIYKLSL
HHHCCCCCCCCCCCCHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]