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The map label for this gene is ykpA [H]

Identifier: 170754707

GI number: 170754707

Start: 1882913

End: 1884493

Strand: Reverse

Name: ykpA [H]

Synonym: CLD_2865

Alternate gene names: 170754707

Gene position: 1884493-1882913 (Counterclockwise)

Preceding gene: 170756910

Following gene: 170754804

Centisome position: 47.61

GC content: 31.63

Gene sequence:

>1581_bases
TTGATTACAGTAACAAATTTAAGTTTAAGATATGGGGACAAAAAACTTTTTGAAGATGTAAACCTTAAATTTACACCTGG
TAACTGCTATGGTGTTATAGGTGCTAATGGCGCCGGCAAGAGTACCTTTTTAAAAATTTTATCTGGAGAAATAGAGGCTA
ATACTGGTGATGTATCTATACAGCCGGGAGTTAGAATGTCTATTTTAAAACAAGATCACTTTAAATACGATGAATTTCCT
GTTTTAGAAACAGTTATAATGGGAAATGAAAGACTTTATCAAATAATGAAAGAAAAAGATGCTATATATGCTAAAACTCC
TTTTACAGATGAAGATGGCATAAAAGCCTCTGAACTAGAGGGAGAATTTGCAGACTTAAACGGTTGGGAAGCAGAAGCAG
AAGCTTCATCCTTACTTCAAGGCTTAGGAATAGGCACAGAGCTTCACGAAAAAGATATGAAGGATTTATCCGGTAGCGAA
AAGGTAAAAGTATTACTAGCTCAGGCATTATTCGGTAATCCTGGAGTTCTTATACTAGATGAGCCTACTAACCACTTAGA
TATAAAATCTGTGAACTGGCTTGAAGAATTCTTAATAAATTTTGAAGGAACAGTTATTGTAGTATCCCATGATAGACATT
TCTTAAATAAAGTATGTACTCACATGGCAGATGTTGACTTTGGTAAAATTAAACTATATGTAGGGAACTATGATTTTTGG
TATGAATCTAGCCAATTAGCGCTTCAAATGGCTAAAGATCAAAACAAGAAAAAAGAAGAAAAAATTAAAGAGCTGCAGGA
ATTCATTGCTCGTTTTAGTGCTAATGCATCTAAATCTAAGCAAGCCACTTCCCGTAAAAAATTATTAGATAAAATCGATT
TAGATAACATACAACCTTCTAGTAGAAAATATCCTTACATAGCCTTTAAACCCGAAAGAGAAGTTGGTAATGATATATTA
AGAGTAGAGGGTTTAACTAAAACTATAGACGGAACAAAAGTATTGGATAATATAAGCTTTATAATAGGTAAAGATGATAA
AATAGCTTTTGTAGGAGACGAATTATCTATAACTACTCTATTTAAAATAATATCTGGTGAACTAGAGCCAGATAGTGGTG
AATATAAATGGGGTATAACTATAACAAATGCTTATTTCCCAAAGGATAACTCTGAATACTTTAATGATGTAGATTTAAAT
TTAGTAGATTGGCTAAGACAATACTCCGAAGAAAAATCTGAAAGCTATCTACGTGGATTCCTAGGAAGAATGTTATTCTC
TGGTGAAGAGGCTTTAAAAGAGGTTAAAGTTCTATCTGGTGGAGAAAAAGTTAGATGTATGCTATCAAAAATGATGCTAA
ATAATGCTAATGTAATTATATTAGATCAACCAACTAACCACTTAGACCTAGAATCTATAACTGCACTAAATAATGGTTTA
ATGGACTATAAGAGTAACATATTATTTACTTCTCATGACCATCAATTTATACAAACTATAGCCAATAGAATTATAGAAGT
ATCTGAAGCAAAATTTGTTGATAAAAAGGTTACTTATGATGAATATTTAGAAAGCAAATAA

Upstream 100 bases:

>100_bases
TTGAAAAGTTTGAAAGATTAACAAATACCTTCTTTTTAAATGGCTTATTTTATGGTATAATGTCGCGAGAACATAAATTT
TAGTAAAGGATGGTATAGAC

Downstream 100 bases:

>100_bases
AAAACTATTTTGAAAATAAAAATCATAAAATCTAGAATGTATAACTAAATATATCAAAAACACTATCAATTTATTAAAAT
TTGATAGTGTTTATTTTTAA

Product: putative drug resistance ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKDMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDIL
RVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK

Sequences:

>Translated_526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKDMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDIL
RVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
>Mature_526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKDMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDIL
RVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=530, Percent_Identity=28.8679245283019, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=31.3543599257885, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=31.3543599257885, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI10947135, Length=533, Percent_Identity=28.1425891181989, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI69354671, Length=533, Percent_Identity=28.1425891181989, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI105990541, Length=204, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=44.5075757575758, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1789751, Length=515, Percent_Identity=31.2621359223301, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI2367384, Length=522, Percent_Identity=30.6513409961686, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1787182, Length=505, Percent_Identity=29.9009900990099, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1790525, Length=561, Percent_Identity=24.777183600713, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787029, Length=246, Percent_Identity=24.7967479674797, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786398, Length=238, Percent_Identity=24.3697478991597, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786872, Length=245, Percent_Identity=27.3469387755102, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=519, Percent_Identity=31.7919075144509, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17555318, Length=511, Percent_Identity=25.8317025440313, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17559834, Length=511, Percent_Identity=27.3972602739726, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17558664, Length=216, Percent_Identity=25.462962962963, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=520, Percent_Identity=31.7307692307692, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6321121, Length=530, Percent_Identity=29.4339622641509, Blast_Score=220, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6325030, Length=248, Percent_Identity=30.6451612903226, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324314, Length=373, Percent_Identity=26.5415549597855, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323278, Length=373, Percent_Identity=25.7372654155496, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24666836, Length=513, Percent_Identity=30.4093567251462, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=27.8810408921933, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=27.8810408921933, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24641342, Length=518, Percent_Identity=29.3436293436293, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI116007184, Length=247, Percent_Identity=25.1012145748988, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=247, Percent_Identity=25.1012145748988, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59481; Mature: 59481

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSI
CEEEEEEEEECCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCEECCCCCEEE
QPGVRMSILKQDHFKYDEFPVLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIKASELE
CCCCEEEHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHCC
GEFADLNGWEAEAEASSLLQGLGIGTELHEKDMKDLSGSEKVKVLLAQALFGNPGVLILD
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEC
EPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIAFKPEREVGNDILRVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTL
CCCCCEEEECCCHHHCCCEEEECCCCCCCCCHHHHCCCEEEEECCCEEEEECCCCHHHHH
FKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCC
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSI
CEEEEEEEEECCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCEECCCCCEEE
QPGVRMSILKQDHFKYDEFPVLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIKASELE
CCCCEEEHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHCC
GEFADLNGWEAEAEASSLLQGLGIGTELHEKDMKDLSGSEKVKVLLAQALFGNPGVLILD
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEC
EPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIAFKPEREVGNDILRVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTL
CCCCCEEEECCCHHHCCCEEEECCCCCCCCCHHHHCCCEEEEECCCEEEEECCCCHHHHH
FKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCC
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]