Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 170754704

GI number: 170754704

Start: 1158827

End: 1160248

Strand: Direct

Name: resE [H]

Synonym: CLD_3515

Alternate gene names: 170754704

Gene position: 1158827-1160248 (Clockwise)

Preceding gene: 170757153

Following gene: 170754999

Centisome position: 29.28

GC content: 28.41

Gene sequence:

>1422_bases
ATGAAAATGTCCTTAAAGAAAATGTCTTTAAAGAAAAAACTTTCTTTAGGATTTTTAATTGCGGTTATAGGTTCAATAAT
AATTGCTAGTTCCATATCTAATTATATGATAAATAACAGATTCAATGAATATTTGGTTCAAGAACATAAAAATAAAATAA
ACCAAATTATAGTGGCAATTGAAGATATGTATAAAGAAGATAAAGGCTTTCAAGCATTAAAGTATGATGAGATAAAAAGA
TATGCAGTTTTAAATGAACTTTATATAGAGATAAAAGATAAAAAGGGGAGCAAGATATTTACCTCTGGGGATGACCATCT
TAAACATAGAAGTATGATGAATTCTATGATGGGGCATGGAATGGGTAATATGATGGGGAAAATGAAAAATTTAGATTTAG
GGGATTATAAAGAAGAAGAACAATGGCTTAAAAAGAACAATGTGACTTTTGGAAAGATAACTATTGGATATTTTGGTACT
TCATATTTAAACAATGGAGCATTAACATTTAAAAGAACCTTAAATCATTCCTTTATTGTATCTATGGTCATAACCTTTAT
TTTAGGGCTTATACTGAGCTGGATTTTATCAAAACAACTTTCAAAACCTTTGGTTAAAATAAAAGAAATAGCTAATACAA
TGAGAATGGGCAATTTAAATATAAGGTCTAATATAAAAAGTAATACGACAGAAATTCAGGAATTATCAAATTCTATAAAT
TATTTAGCAGAAACACTACAACAACAGGAGGCTCTTCGTAAAAGATTGACTTCAGATATGGCTCATGAAATAAGAACTCC
AATTACGACTTTAAAAACTCATGTTGAGGCAATAATAGATGGTATATGGGAGCCTACAGAGGAAAGATTGCAGGTTTTTT
ATGAGGAATTAGAGCGATTAACAAATCTTGTGAATAATTTAAGAAATATTTCTAAATTAGAAAAAGCCGAAACAGTTGTA
AATAAAACTAACTTAAATATTACAACGGAAATAGAAAAAGTTGTAGAAACATTTAATCCCTTATACGAAAAAAGCGGCTT
TAAAATAGTTACTAAACTAGAGAAAGATGTATATGGTTTTATAGATAAGGATAAATTAAAGCAAATTATGCATAATCTTT
TATCTAATTCACATAAATATTTAAATGAAGATGGATTAGTAAAGGTTTCATTATCAAAGGGAGAAGATAAAATATTTATA
AAGGTTGAAGATAATGGAGAGGGGATTCCAAAGGAGGATTTACCTCATATATTTGAAAGATTTTATAGAAGTGATGTATC
AAGGAATAAAACTACAGGAGGTACAGGTCTTGGTCTTACCATAACAAAAACTTTAGTAGAAGCTCATGGTGGGCATATTA
GAGTAGAAAGTAAGATGGGAGTTGGAACCAAGTTTATTATAGAGATAAAAACTACTCTTTAG

Upstream 100 bases:

>100_bases
ATATAAAAAATATAAGACAAAAGATAGAAGATAATCCTAAAGCTCCTAACTATATTACTACTGTATATGGAGTTGGATAC
AGATTTGGAGGAAAAAATTA

Downstream 100 bases:

>100_bases
ATTTAAGTTTATTGTAAAAATATTTTTATTATTTTGTCCTATAATTTTATAAAGGTTTTATCTTTTTTGTTGCTTTGCTT
TTGTTTAAGGATGAATTTTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKMSLKKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKR
YAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGT
SYLNNGALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSIN
YLAETLQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVV
NKTNLNITTEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGEDKIFI
KVEDNGEGIPKEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL

Sequences:

>Translated_473_residues
MKMSLKKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKR
YAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGT
SYLNNGALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSIN
YLAETLQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVV
NKTNLNITTEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGEDKIFI
KVEDNGEGIPKEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
>Mature_473_residues
MKMSLKKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKR
YAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGT
SYLNNGALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSIN
YLAETLQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVV
NKTNLNITTEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGEDKIFI
KVEDNGEGIPKEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=29.3040293040293, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1786783, Length=395, Percent_Identity=28.6075949367089, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=27.2388059701493, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=31.3304721030043, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789149, Length=344, Percent_Identity=27.0348837209302, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=24.8299319727891, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=26.6932270916335, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87081816, Length=261, Percent_Identity=24.5210727969349, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=22.3938223938224, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=22.742474916388, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789403, Length=288, Percent_Identity=25.3472222222222, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788279, Length=278, Percent_Identity=24.4604316546763, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=27.5229357798165, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=26.9406392694064, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790551, Length=305, Percent_Identity=25.5737704918033, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=289, Percent_Identity=21.1072664359862, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=25.7936507936508, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=385, Percent_Identity=21.8181818181818, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=23.7068965517241, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54135; Mature: 54135

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSLKKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
EDMYKEDKGFQALKYDEIKRYAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHCC
MGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNNGALTFKRTLNHSFIV
HHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEEHHHHHHCCCCEEEHHHHCHHHHH
SMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
YLAETLQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TNLVNNLRNISKLEKAETVVNKTNLNITTEIEKVVETFNPLYEKSGFKIVTKLEKDVYGF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCC
IDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGEDKIFIKVEDNGEGIPKEDLPHIFER
CCHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHH
FYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKMSLKKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
EDMYKEDKGFQALKYDEIKRYAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHCC
MGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNNGALTFKRTLNHSFIV
HHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEEHHHHHHCCCCEEEHHHHCHHHHH
SMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
YLAETLQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TNLVNNLRNISKLEKAETVVNKTNLNITTEIEKVVETFNPLYEKSGFKIVTKLEKDVYGF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCC
IDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGEDKIFIKVEDNGEGIPKEDLPHIFER
CCHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHH
FYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]