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The map label for this gene is ycbL [H]

Identifier: 170757153

GI number: 170757153

Start: 1158126

End: 1158827

Strand: Direct

Name: ycbL [H]

Synonym: CLD_3516

Alternate gene names: 170757153

Gene position: 1158126-1158827 (Clockwise)

Preceding gene: 170756106

Following gene: 170754704

Centisome position: 29.26

GC content: 31.2

Gene sequence:

>702_bases
ATGAAGAAACTCTTTAAAATATTAGTTGTAGATGATGAAGAAAGGATATTAGATGTGGTAAAAGCTTATTTAGAAAAAGA
AGATTATGAAGTGATAACTGCAATGGATGGTGAGGAAGCAATTAAGTTATTTAAAGAAACATCATTTCATTTAATTATAT
TGGATTTAATGCTACCAAAGTTATCTGGTGAAGAGGTTTGTTCAAAGATAAGAGAATCTTCTAATGTTCCAATTATTATG
CTTACAGCAAAGGTAGAGGAAGAGGATAAGCTAGAAGGTCTTTCTATAGGAGCAGATGATTATCTTACAAAACCTTTTAG
TGTAAGGAAACTTGTGGCAAGAGTCAAGGCTCTTATTAGAAGGGCATATAGAGGAAAGTATCCATTGGCAGAGCATCTAA
TACTTAATGATGGAGACTTAGAAGTTGACATAAGAAAAATGAAAGTATTAAAAAACGGAAAGGCGGTTACATTAACACCT
TATGAGTTTAAAGTGCTTGTTTCACTATTAACTAATCCAGGGCAGGTTTTTACTAGAGAACAGTTAGTTGAACAAGCTTT
TGGATATGATTATGAAAGTTTTGATAGGACTGTAGATACTTATATAAAAAATATAAGACAAAAGATAGAAGATAATCCTA
AAGCTCCTAACTATATTACTACTGTATATGGAGTTGGATACAGATTTGGAGGAAAAAATTAA

Upstream 100 bases:

>100_bases
GCTGAAGAGTTCTAATACATACTAAGTTTATAAACATTAAGAACATTATCAATAATAGTAATGGGATGGAAGTTAAATAT
AAATGGTTAGGAGAGAAGAT

Downstream 100 bases:

>100_bases
TGAAAATGTCCTTAAAGAAAATGTCTTTAAAGAAAAAACTTTCTTTAGGATTTTTAATTGCGGTTATAGGTTCAATAATA
ATTGCTAGTTCCATATCTAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKKLFKILVVDDEERILDVVKAYLEKEDYEVITAMDGEEAIKLFKETSFHLIILDLMLPKLSGEEVCSKIRESSNVPIIM
LTAKVEEEDKLEGLSIGADDYLTKPFSVRKLVARVKALIRRAYRGKYPLAEHLILNDGDLEVDIRKMKVLKNGKAVTLTP
YEFKVLVSLLTNPGQVFTREQLVEQAFGYDYESFDRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN

Sequences:

>Translated_233_residues
MKKLFKILVVDDEERILDVVKAYLEKEDYEVITAMDGEEAIKLFKETSFHLIILDLMLPKLSGEEVCSKIRESSNVPIIM
LTAKVEEEDKLEGLSIGADDYLTKPFSVRKLVARVKALIRRAYRGKYPLAEHLILNDGDLEVDIRKMKVLKNGKAVTLTP
YEFKVLVSLLTNPGQVFTREQLVEQAFGYDYESFDRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN
>Mature_233_residues
MKKLFKILVVDDEERILDVVKAYLEKEDYEVITAMDGEEAIKLFKETSFHLIILDLMLPKLSGEEVCSKIRESSNVPIIM
LTAKVEEEDKLEGLSIGADDYLTKPFSVRKLVARVKALIRRAYRGKYPLAEHLILNDGDLEVDIRKMKVLKNGKAVTLTP
YEFKVLVSLLTNPGQVFTREQLVEQAFGYDYESFDRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=37.9310344827586, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=40.8695652173913, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=34.7826086956522, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.5, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=35.2678571428571, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=35.2422907488987, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32.8888888888889, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.0043668122271, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.4159292035398, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=31.25, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=31.7180616740088, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.6137339055794, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788550, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=116, Percent_Identity=36.2068965517241, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=133, Percent_Identity=27.8195488721804, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26708; Mature: 26708

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00230 MAP1B_NEURAXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFKILVVDDEERILDVVKAYLEKEDYEVITAMDGEEAIKLFKETSFHLIILDLMLPK
CCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCHHEEEEEHHCCC
LSGEEVCSKIRESSNVPIIMLTAKVEEEDKLEGLSIGADDYLTKPFSVRKLVARVKALIR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHHHHHH
RAYRGKYPLAEHLILNDGDLEVDIRKMKVLKNGKAVTLTPYEFKVLVSLLTNPGQVFTRE
HHHCCCCCCHHHEEECCCCCEEHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHH
QLVEQAFGYDYESFDRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEECCEECCCCC
>Mature Secondary Structure
MKKLFKILVVDDEERILDVVKAYLEKEDYEVITAMDGEEAIKLFKETSFHLIILDLMLPK
CCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCHHEEEEEHHCCC
LSGEEVCSKIRESSNVPIIMLTAKVEEEDKLEGLSIGADDYLTKPFSVRKLVARVKALIR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHHHHHH
RAYRGKYPLAEHLILNDGDLEVDIRKMKVLKNGKAVTLTPYEFKVLVSLLTNPGQVFTRE
HHHCCCCCCHHHEEECCCCCEEHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHH
QLVEQAFGYDYESFDRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]