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The map label for this gene is cbiC

Identifier: 170754657

GI number: 170754657

Start: 1045962

End: 1046588

Strand: Direct

Name: cbiC

Synonym: CLD_3634

Alternate gene names: 170754657

Gene position: 1045962-1046588 (Clockwise)

Preceding gene: 170755038

Following gene: 170755426

Centisome position: 26.42

GC content: 32.06

Gene sequence:

>627_bases
ATGAAAAATTATATAAAAAAGCCAATGGATATAGAAAAAAGAAGTTTTGAAATAATAGAAGAAGAGATGGGTAAGCACAA
TTTTTCAAAAGAAGAATTAAAGATAGTGAAAAGAGTAATACATACTACCGCAGATTTTGAATATAAGGATTTAATTTATA
TAAAGGAAGGGGCCATAGAGGCAGCAAAAGAAATTCTTACAAAGGGTACAAAGATTTATACAGATACCAACATGGCTTTA
TCAGGTATAAATAAAAAGGCCTTAAAGGATTTAAACTCTACAGTTCAGTGTTTTGTATCTAGAGAGGATGTAGCTTTAAT
TGCAAAAGATAGAGGCATAACAAGATCTATGGCAGCAGTAGAGATGGCAGCAGAAGAAGGGATAGAATTTTTTGTCTTCG
GAAATGCTCCAACAGCTCTTTACAAATTAATGGAACTTATGAAAGAGGGAAAAGTAAATCCAAAATTTATAATAGGAGTA
CCAGTAGGCTTTGTAGGGGCGGCAGAATCAAAAAGAGAATTAGAAAAATTAGATGTACCTTTTATAACTATAAGAGGAAG
AAAAGGTGGCAGCAATGTAGCAGCTTCTATAGTAAATGCACTAATGTATATGCTAATAAAAAGATAG

Upstream 100 bases:

>100_bases
TAATACGTTGGCAGCATATGCTCATGTACATTTCTTCGGAAATATGGATTTTGTAAGAAATTTATTTAATAGATAAAAAG
AAAATTAGAGAGGTAAGGGT

Downstream 100 bases:

>100_bases
AAATATTTTATTCATAGTATGAAATAAAGTTAACTTAAATTTTGAAAATGTAGATAGAGGAAATGTTCTTTGAAAATTTA
ATAAGATGGTGTTTTAAAAC

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKNYIKKPMDIEKRSFEIIEEEMGKHNFSKEELKIVKRVIHTTADFEYKDLIYIKEGAIEAAKEILTKGTKIYTDTNMAL
SGINKKALKDLNSTVQCFVSREDVALIAKDRGITRSMAAVEMAAEEGIEFFVFGNAPTALYKLMELMKEGKVNPKFIIGV
PVGFVGAAESKRELEKLDVPFITIRGRKGGSNVAASIVNALMYMLIKR

Sequences:

>Translated_208_residues
MKNYIKKPMDIEKRSFEIIEEEMGKHNFSKEELKIVKRVIHTTADFEYKDLIYIKEGAIEAAKEILTKGTKIYTDTNMAL
SGINKKALKDLNSTVQCFVSREDVALIAKDRGITRSMAAVEMAAEEGIEFFVFGNAPTALYKLMELMKEGKVNPKFIIGV
PVGFVGAAESKRELEKLDVPFITIRGRKGGSNVAASIVNALMYMLIKR
>Mature_208_residues
MKNYIKKPMDIEKRSFEIIEEEMGKHNFSKEELKIVKRVIHTTADFEYKDLIYIKEGAIEAAKEILTKGTKIYTDTNMAL
SGINKKALKDLNSTVQCFVSREDVALIAKDRGITRSMAAVEMAAEEGIEFFVFGNAPTALYKLMELMKEGKVNPKFIIGV
PVGFVGAAESKRELEKLDVPFITIRGRKGGSNVAASIVNALMYMLIKR

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 23334; Mature: 23334

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYIKKPMDIEKRSFEIIEEEMGKHNFSKEELKIVKRVIHTTADFEYKDLIYIKEGAIE
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCHHH
AAKEILTKGTKIYTDTNMALSGINKKALKDLNSTVQCFVSREDVALIAKDRGITRSMAAV
HHHHHHHCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
EMAAEEGIEFFVFGNAPTALYKLMELMKEGKVNPKFIIGVPVGFVGAAESKRELEKLDVP
HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHCCCC
FITIRGRKGGSNVAASIVNALMYMLIKR
EEEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNYIKKPMDIEKRSFEIIEEEMGKHNFSKEELKIVKRVIHTTADFEYKDLIYIKEGAIE
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCHHH
AAKEILTKGTKIYTDTNMALSGINKKALKDLNSTVQCFVSREDVALIAKDRGITRSMAAV
HHHHHHHCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
EMAAEEGIEFFVFGNAPTALYKLMELMKEGKVNPKFIIGVPVGFVGAAESKRELEKLDVP
HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHCCCC
FITIRGRKGGSNVAASIVNALMYMLIKR
EEEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1451790 [H]