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The map label for this gene is manR [H]

Identifier: 170754654

GI number: 170754654

Start: 2293152

End: 2295245

Strand: Reverse

Name: manR [H]

Synonym: CLD_2486

Alternate gene names: 170754654

Gene position: 2295245-2293152 (Counterclockwise)

Preceding gene: 170755440

Following gene: 170755077

Centisome position: 57.99

GC content: 28.41

Gene sequence:

>2094_bases
GTGTTAAATAAAAGATGCTCAAATATCTTGCAGATGATAGTAAATAACGAAAGGCCTATAACTATAAAGGAAATTTCTAA
AAAAGTCAATAAAAGTCCTAGAACTGTAAGATATGATTTAGATAAAATAGATGATTATTTAACTGAGATTGAATTTCCTA
AACTTGAAAGAAAATCCAATTTAGGCATCAGCCTAGATTTAAAGGATGAAGAAATAAAAAAACTTTTTAAGATTATAGGC
AAAATTAATAATTATGACTATGTTCTTTCTCAAAAAGAGAGAGTATTTTATATAATTTATGAGCTTTTAAATAAGAGTGA
ATTTGTAACTATAAATATGCTTTCAGATAGGATGATGGTAAGCCGCAGTACTATAATAAATGATTTAATAGAGGTTAAAA
AATGGCTATTAGAAAATAAAATAACCCTTGAAAGTTCAAAGGGACAGGGCATAAAAATATTGGGAAGAGAAAGGGATCTT
AGACGGGCTGCAGTAAAGCTCTTTTTTCAGAGCATGGATTCTATAAACTTTTTCAATGTAACTACCCTTAAGCTTTTTAA
TGATATAGATATAGACTTTATAAGAAATACTATTAAAATTGCAGAGGAGCAGATGGAAACTTCATTTTCAGATGATGCTT
TTAATAATCTTGTTATTCATATAGCTATAGCCATTAAAAGAATAGAATTATCAAAGGATATAATAATGGATAGCGAAGAA
CTTAAGAATCTAAGGAAAACTGCGGAATATGCCATTGCATCAGGTGTAGCTAAAATGCTTGAGGATAGATTTAAAATATT
TATACCAGAGGACGAAATAGGCTATATAACAATTCATATTTTAGGTAGCAATACTTCTACCCTTGAAAATATTGTAAAGG
ATGATTGGATTTATCTACATCTTATAGTATTTAAACTAATAGAAAATGTAGAAAACATAACAGGAATTAATTTTAGTAAG
GATAATAAGCTTTTTGATAGTCTTGCTCAGCATATTCGTCCAGCTATATACAGGCTTAAACATGATATTAAAGTAAAAAA
TCCATTGATAGAAGAAATAAAAGAAAAATATTCATATATATTTGAAAGTATAGAGGAAGGTGTAAAGTTCATAGAAGAGG
ATATAGGTGATAGTGTAAATCAAGAGGAAATAGGATATCTTACACTACACTTTATGGCTTCCATAGAAAGAAGCAAAAAT
AAAAAACATAGAAAACCAAATGTACTTATAGTATGCGCCACAGGCATAGGTACATCAAAGTTTATTTCTAATAAATTAAA
ATCTATATTTGATATAAATATAATAGATACTATATCTAGCCATACTATGGAAAAGATCCTTAAATATAATAAAAACATAG
ATTTAATTGTAACTACAATTCCATTAAAGGTTAAGGGGATAAAATGTATAGAAGTAAATACATTTTTAACAGAAAAAAAC
ATCAGTGAATTAGGCTTATACTTTGCAAAATTTATTAGAGATAACAGTGAAGAATGCAATAGTTCCTGTAAATATGAAGA
AAGAGATAAGGTGCAGGAGATTTTAAATATTGTAAAAGAAAATTGCACTATACATGATTATTATAAATTAAGAAATAAGC
TAGCGCTATATTTGGATATAAAAGATCCTGCCCTTACTGAAAATCATAAACCTTCTTTAAAGGAACTACTAAAACCTGAT
TTTATTAAATTAAATGAAGAAGCTAAAGACTGGGAAGATGCAGTAAGAAAAAGTGGGGAGATATTAATGAATAATGGATG
TATAAAGGAATCCTATATAGATGCTATGGTAAACACAGTAAAGAATATGGGCCCTTATATTGTTATAGCTCCTGGAATAG
CTATGCCCCATGCAGCACCAGAGGATGGAGTTCTAAAAACTGGTATAAGTATGCTAACCTTAAAAGATCCAATTTCCTTT
GGAAATTCTGAACATGATCCAGTAAGTGTTATAATTTCAATATGTTCTATAGATAAAGTAAACCATATGAAGGCACTAAA
AGAGTTAATGAGTATTATGGATCAGGAAGATTTCATCTCAAAGGTTAAAAGTATGAAAACTCCCTCTGAAATAGATCCCA
TTTTATATAGTTAA

Upstream 100 bases:

>100_bases
TATTTTATTGTGGATTATTACGCATTTTAAGTAATAGAGTAAATAAATTTTATTTAGCAATTATATTTTTATATTTAAAC
ACTAAAGGGGATGATGCATC

Downstream 100 bases:

>100_bases
ATTAAATAATAAAAACAAAAGCTCTCATAATCTGGGAGCTTTTGTTTTGTAATAATTTATAAGCTTATTTTTTATATTTA
AGATAATAAGCTCTAATTGA

Product: PRD domain-containing protein

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MLNKRCSNILQMIVNNERPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIG
KINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDL
RRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEE
LKNLRKTAEYAIASGVAKMLEDRFKIFIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSK
DNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKN
KKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKN
ISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLDIKDPALTENHKPSLKELLKPD
FIKLNEEAKDWEDAVRKSGEILMNNGCIKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISF
GNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFISKVKSMKTPSEIDPILYS

Sequences:

>Translated_697_residues
MLNKRCSNILQMIVNNERPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIG
KINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDL
RRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEE
LKNLRKTAEYAIASGVAKMLEDRFKIFIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSK
DNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKN
KKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKN
ISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLDIKDPALTENHKPSLKELLKPD
FIKLNEEAKDWEDAVRKSGEILMNNGCIKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISF
GNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFISKVKSMKTPSEIDPILYS
>Mature_697_residues
MLNKRCSNILQMIVNNERPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIG
KINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDL
RRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEE
LKNLRKTAEYAIASGVAKMLEDRFKIFIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSK
DNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKN
KKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKN
ISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLDIKDPALTENHKPSLKELLKPD
FIKLNEEAKDWEDAVRKSGEILMNNGCIKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISF
GNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFISKVKSMKTPSEIDPILYS

Specific function: May regulate the expression of the mannose operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=131, Percent_Identity=34.3511450381679, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1790755, Length=127, Percent_Identity=31.496062992126, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789302, Length=107, Percent_Identity=40.1869158878505, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2 [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 80339; Mature: 80339

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKRCSNILQMIVNNERPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSN
CCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCCCCC
LGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMV
CCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEEHHHHHHH
SRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNV
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
TTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEE
EEEEHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEHHHHHHHHHHHHHCCHHH
LKNLRKTAEYAIASGVAKMLEDRFKIFIPEDEIGYITIHILGSNTSTLENIVKDDWIYLH
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHH
LIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
FISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEECCEEEEEEEHHHHHCC
ISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLDI
HHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEEE
KDPALTENHKPSLKELLKPDFIKLNEEAKDWEDAVRKSGEILMNNGCIKESYIDAMVNTV
CCCCCCCCCCCHHHHHCCCCCEEECCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
KNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKV
HHCCCEEEEECCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCHH
NHMKALKELMSIMDQEDFISKVKSMKTPSEIDPILYS
HHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLNKRCSNILQMIVNNERPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSN
CCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCCCCC
LGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMV
CCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEEHHHHHHH
SRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNV
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
TTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEE
EEEEHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEHHHHHHHHHHHHHCCHHH
LKNLRKTAEYAIASGVAKMLEDRFKIFIPEDEIGYITIHILGSNTSTLENIVKDDWIYLH
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHH
LIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
FISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEECCEEEEEEEHHHHHCC
ISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLDI
HHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEEE
KDPALTENHKPSLKELLKPDFIKLNEEAKDWEDAVRKSGEILMNNGCIKESYIDAMVNTV
CCCCCCCCCCCHHHHHCCCCCEEECCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
KNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKV
HHCCCEEEEECCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCHH
NHMKALKELMSIMDQEDFISKVKSMKTPSEIDPILYS
HHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]