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The map label for this gene is msmR [H]

Identifier: 170754624

GI number: 170754624

Start: 803834

End: 804655

Strand: Direct

Name: msmR [H]

Synonym: CLD_0081

Alternate gene names: 170754624

Gene position: 803834-804655 (Clockwise)

Preceding gene: 170757057

Following gene: 170755421

Centisome position: 20.31

GC content: 36.74

Gene sequence:

>822_bases
ATGGAAGTCGACTTAATGGATATAGTAGAACACTTTGCCCATACCGCTTTTCAAGTAGAAGGAGTATATAATTATAGTAT
TGAACCGGGGAGTGCGGGCATTATGAAAACTTCTCCATTTCCAGGATTTATCTTTCCCTTGGCAGGTCAGGCGAATTTCA
TTTTTGATGGTACTTCTTACACAGCAGGCCTTGGAAATGTGATTCATGGTGGCGCAAATATGAGGTTGAGTAAGAAGGTA
ATTGGTAAAAAAAAATGGAATTATATTTTGGTCCTTTACAGTATTCGTAAGCCTGAACCGGAAGGATTTTCCCTAGAGGA
TTTACATTTTGAACTTGTTCTAGGACAAAGTCCTAGACTCTTTGATTTGCTACAACGATTATGGAGAGTATCAAATCAAC
CTGGAGCAATTGCTACATTTCAAAAGGAAACCATATTTCGTTGTGTATTGGATGAAATTTTTATATGTACACGTAACCAG
TCGAGTGGTGATGATCGTATATTGTTTAGACAAGTATCTGATTACATTCACGAATATTATATGGACACACTTACTATTCG
ATCTCTTGCTGAACTACATGGGGTAAATGAGAATAGATTGTTCTATGTATTCTCAAAATATGCAGGAATGGGAGCAGGAG
ATTATCTTATGATTCATAGGCTAAATCGTGCAAAGGAACTGTTGGTAACAGGTAATGCTCCTGTAGTAGCGGTAGCGAAA
AGTGTGGGTTATCATGATCCATATCATTTTAGTAAGAGATTTAAAAAGCAATTTGGTATTTCTCCAAGTAAATTTCGGGA
CAAGTTCAGATATAAAGGATGA

Upstream 100 bases:

>100_bases
AATCATTAAGAGTTTTTCATAAATGATTGAGCTATTTTTTAAAAGAAAATATATTATGGGGAAATTGCTATAAAACTTAG
TAAAAAAGGGGGAGCATTAA

Downstream 100 bases:

>100_bases
TGCTTTTAGTCTGTTTACCATTTTAGTAGAATTAAATCACGTTATACTATTTACTCTTCATATTTAAATAGATGAAAGAA
AGTTTTTAGATTCTTATTTT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEVDLMDIVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGQANFIFDGTSYTAGLGNVIHGGANMRLSKKV
IGKKKWNYILVLYSIRKPEPEGFSLEDLHFELVLGQSPRLFDLLQRLWRVSNQPGAIATFQKETIFRCVLDEIFICTRNQ
SSGDDRILFRQVSDYIHEYYMDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG

Sequences:

>Translated_273_residues
MEVDLMDIVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGQANFIFDGTSYTAGLGNVIHGGANMRLSKKV
IGKKKWNYILVLYSIRKPEPEGFSLEDLHFELVLGQSPRLFDLLQRLWRVSNQPGAIATFQKETIFRCVLDEIFICTRNQ
SSGDDRILFRQVSDYIHEYYMDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG
>Mature_273_residues
MEVDLMDIVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGQANFIFDGTSYTAGLGNVIHGGANMRLSKKV
IGKKKWNYILVLYSIRKPEPEGFSLEDLHFELVLGQSPRLFDLLQRLWRVSNQPGAIATFQKETIFRCVLDEIFICTRNQ
SSGDDRILFRQVSDYIHEYYMDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=110, Percent_Identity=33.6363636363636, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31148; Mature: 31148

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVDLMDIVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGQANFIFDGTSY
CCCCHHHHHHHHHHHEEEEEEEEEEEECCCCCCCEECCCCCCEEEECCCCCEEEECCCCC
TAGLGNVIHGGANMRLSKKVIGKKKWNYILVLYSIRKPEPEGFSLEDLHFELVLGQSPRL
CCCCCHHEECCCCCEEHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHEEEEEEECCCCCH
FDLLQRLWRVSNQPGAIATFQKETIFRCVLDEIFICTRNQSSGDDRILFRQVSDYIHEYY
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHH
MDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEH
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG
HCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MEVDLMDIVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGQANFIFDGTSY
CCCCHHHHHHHHHHHEEEEEEEEEEEECCCCCCCEECCCCCCEEEECCCCCEEEECCCCC
TAGLGNVIHGGANMRLSKKVIGKKKWNYILVLYSIRKPEPEGFSLEDLHFELVLGQSPRL
CCCCCHHEECCCCCEEHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHEEEEEEECCCCCH
FDLLQRLWRVSNQPGAIATFQKETIFRCVLDEIFICTRNQSSGDDRILFRQVSDYIHEYY
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHH
MDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEH
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG
HCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]