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The map label for this gene is hmp [H]

Identifier: 170754590

GI number: 170754590

Start: 2489553

End: 2490326

Strand: Reverse

Name: hmp [H]

Synonym: CLD_2272

Alternate gene names: 170754590

Gene position: 2490326-2489553 (Counterclockwise)

Preceding gene: 170755621

Following gene: 170757217

Centisome position: 62.92

GC content: 25.97

Gene sequence:

>774_bases
ATGATACATAATAAAGTGAATTTACGTAATACATGGAGAGGATTTAAAGATTGTATAGTATTTAATAAAGTTAAAGAAAG
TGAAAGCGTCACATCATTATACTTGAAATTATTAGATGGAAATAAACTCCCTGAGTTCATAGCAGGGCAATTTATAGCCA
TTAGAATTAGAAATAAGGATAATACTTATACAAAACCTAGAGAATATACATTGTCTATAAATTCTAATAAAGAATTTTAT
AGGATAAGTGTAAAGAGAGAAGAAAATGGATCTTTAAGTAAAAAATTATATGATGAGATAAAGATAGGGGATGTTATTCA
AATAACTGTACCAATTGGAAAGTTTACATTAAAAAATAATGAAAAGCCATTAGTTTTAATAGGAGGAGGAATTGGAATAA
CACCAATGATTGCAATGACTCACCAAGCAATAAATACTAGTAGAAAAATACATTTTGTTTATAGTATACCGAATTCAAAG
AATCATAGCTTTAAAGAAGAAATAGAAAAGTTATGTGAAAATAATAATTTCAAAAGTAATATATTTTACACACGTCCCTA
TGAAACGGATGATTTGATAAAAAGTTTTTATACAAAAGGTAGAATATCAAAGGAATGGATGATAGATAATTTACCGAAGG
ATGGAGATTTTTATTTTTGTGGACCAGTATTATTTATGAAGGATATTTATCATAATTTAGTATCTATGGGAATTGAAAAG
GAGTATATAAACTTTGAAATGTTTAAATCAGGAGAAGATATAACAAAAGATTAA

Upstream 100 bases:

>100_bases
ATTCATTTTTATGAATATATAATAAGTTCATAAATCAAAGCAAACCAATTCAAGAAAAATAAACTTGAAAATAAAAATCT
AAAGAAAAAGGAGGAGTTCA

Downstream 100 bases:

>100_bases
GAATGCAAATAATTAAGGAGGCAACACATTATGTTTGATTGTATAAGGGATAAAAATAAGAGTTTTAAAAATTTAATAAA
TGGAGAATAGGTTAATAGTA

Product: putative flavohemoprotein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIHNKVNLRNTWRGFKDCIVFNKVKESESVTSLYLKLLDGNKLPEFIAGQFIAIRIRNKDNTYTKPREYTLSINSNKEFY
RISVKREENGSLSKKLYDEIKIGDVIQITVPIGKFTLKNNEKPLVLIGGGIGITPMIAMTHQAINTSRKIHFVYSIPNSK
NHSFKEEIEKLCENNNFKSNIFYTRPYETDDLIKSFYTKGRISKEWMIDNLPKDGDFYFCGPVLFMKDIYHNLVSMGIEK
EYINFEMFKSGEDITKD

Sequences:

>Translated_257_residues
MIHNKVNLRNTWRGFKDCIVFNKVKESESVTSLYLKLLDGNKLPEFIAGQFIAIRIRNKDNTYTKPREYTLSINSNKEFY
RISVKREENGSLSKKLYDEIKIGDVIQITVPIGKFTLKNNEKPLVLIGGGIGITPMIAMTHQAINTSRKIHFVYSIPNSK
NHSFKEEIEKLCENNNFKSNIFYTRPYETDDLIKSFYTKGRISKEWMIDNLPKDGDFYFCGPVLFMKDIYHNLVSMGIEK
EYINFEMFKSGEDITKD
>Mature_257_residues
MIHNKVNLRNTWRGFKDCIVFNKVKESESVTSLYLKLLDGNKLPEFIAGQFIAIRIRNKDNTYTKPREYTLSINSNKEFY
RISVKREENGSLSKKLYDEIKIGDVIQITVPIGKFTLKNNEKPLVLIGGGIGITPMIAMTHQAINTSRKIHFVYSIPNSK
NHSFKEEIEKLCENNNFKSNIFYTRPYETDDLIKSFYTKGRISKEWMIDNLPKDGDFYFCGPVLFMKDIYHNLVSMGIEK
EYINFEMFKSGEDITKD

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=248, Percent_Identity=29.8387096774194, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1788104, Length=232, Percent_Identity=24.1379310344828, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321673, Length=216, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 29946; Mature: 29946

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHNKVNLRNTWRGFKDCIVFNKVKESESVTSLYLKLLDGNKLPEFIAGQFIAIRIRNKD
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCEEEEEEECCC
NTYTKPREYTLSINSNKEFYRISVKREENGSLSKKLYDEIKIGDVIQITVPIGKFTLKNN
CCCCCCCEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCEEEEECC
EKPLVLIGGGIGITPMIAMTHQAINTSRKIHFVYSIPNSKNHSFKEEIEKLCENNNFKSN
CCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCC
IFYTRPYETDDLIKSFYTKGRISKEWMIDNLPKDGDFYFCGPVLFMKDIYHNLVSMGIEK
EEEECCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCH
EYINFEMFKSGEDITKD
HHCCEEEECCCCCCCCC
>Mature Secondary Structure
MIHNKVNLRNTWRGFKDCIVFNKVKESESVTSLYLKLLDGNKLPEFIAGQFIAIRIRNKD
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCEEEEEEECCC
NTYTKPREYTLSINSNKEFYRISVKREENGSLSKKLYDEIKIGDVIQITVPIGKFTLKNN
CCCCCCCEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCEEEEECC
EKPLVLIGGGIGITPMIAMTHQAINTSRKIHFVYSIPNSKNHSFKEEIEKLCENNNFKSN
CCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCC
IFYTRPYETDDLIKSFYTKGRISKEWMIDNLPKDGDFYFCGPVLFMKDIYHNLVSMGIEK
EEEECCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCH
EYINFEMFKSGEDITKD
HHCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]