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The map label for this gene is mtaD [H]

Identifier: 170755621

GI number: 170755621

Start: 2490552

End: 2491865

Strand: Reverse

Name: mtaD [H]

Synonym: CLD_2271

Alternate gene names: 170755621

Gene position: 2491865-2490552 (Counterclockwise)

Preceding gene: 170757718

Following gene: 170754590

Centisome position: 62.95

GC content: 26.94

Gene sequence:

>1314_bases
ATGCTAATTAAAAATATTACGTTAATAGATGAAAATTATGATGTTATAGAAAATAGTAATATAGTTATAGAAGAAAATGT
AATAAGTTATATAGGTAAAGACATACCTCAAAATTATGCGGATTATATTTATGATGGGAAAAATAAAGTTGCTGTTCCAG
GATTATTTAATATGCATTGCCATGTACCAATGACTTTAGTCAGAGGATATGGAGAAGGTTTACCACTTAATAGGTGGTTA
AGTGAAAAAATATGGCCATTTGAATACTTTCTTACAGATGAAGATTGTTATTACGGATCATTGTTAGGAATTTCAGAAAT
GATTAAAAGTGGAGTGGTATCTTTTAATGATATGTATTTTAATTTAGAAGGAATATTAAAAGCTGTTTATGAAACAGGAA
TTAAAGCTAATCTATCTTATGGCTATGTTGATACTCCGGAAAACCAAGATTATTTTAAAGGGAATGCTTATAAACAAACA
AAGATGTTAAATGATTACATAAAAAATACTAATACTGATAGGATAAAAGCTGATGTTTCAATTCATGCTGTCTATACTTC
TTCTGAGGATTCAGTTAGAAAAATTTCTGAATACTGTAACAGCACAAAGATGAATATGCATATTCATTTATCTGAAACAG
AATTGGAAATAAAAGAATGTAAAAAAAGATTTGGAGTAACTCCAGTAGAATATTTTTTAAATTGTGGAACATTTAAAAGT
AATACAATAGCGGCTCATTGTGTACATCTTGAAGATGATGATTTTTCTATACTAAAAGAAAATAACGTTACAATAGCTCA
TTGTCCAAGTAGTAATTTAAAACTAGGAAGTGGAATAGCTCCTTTAAAAGCTATGTTAAAGTATGAAATAAATGTGACTA
TTGGAACAGATGGTGCAGCAAGTAATAATAATCTAAATATGATAGAAGAGGTCAATCTTGCAGCTTTATTACATAAAGGA
GTTAATAAAGACCCATTATTTTTAAGTCCAAAAGAAATTATAAAAATTTCTTCTTTAAATGGTGCTAAGGCTCAAGGTAG
GAAGGATTGTGGATCAATAAAGATAGGAAATAGGGCAGATATTGTAATTTATGATTTTAATAAACCTCATATGAAACCTA
TACATGATGTTTTAGCTAATTTAATTTATTCTGCACAATCTGATGATATATGCCTAACTATAATAGATGGGAATATAGTA
TATAAAGATGGAACGTTTACTAATATAGATATAGAAAAAGTTTACTATAATATAAATAGAATAAAAAATCAAAAGTTAAA
AATGGTAAGTAATATAGGGAATAATATTATTTAG

Upstream 100 bases:

>100_bases
TAAAAGAGTTAACTTATGATTAGCTATTATGTTTTTTTATGTAGAGGCTTAAGAAGTTTTATGGCTTTATAAAAATATTA
ATAAAATAGGGGGAGATTTT

Downstream 100 bases:

>100_bases
CATTTTAGAAATATGGATATTTTGAAAATAAACTAGCCAATAGAATCCTAACTACTTAGTTGTAGTTAGGATTTATTTTT
ATATATTCTAGATATTTTTT

Product: amidohydrolase family protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MLIKNITLIDENYDVIENSNIVIEENVISYIGKDIPQNYADYIYDGKNKVAVPGLFNMHCHVPMTLVRGYGEGLPLNRWL
SEKIWPFEYFLTDEDCYYGSLLGISEMIKSGVVSFNDMYFNLEGILKAVYETGIKANLSYGYVDTPENQDYFKGNAYKQT
KMLNDYIKNTNTDRIKADVSIHAVYTSSEDSVRKISEYCNSTKMNMHIHLSETELEIKECKKRFGVTPVEYFLNCGTFKS
NTIAAHCVHLEDDDFSILKENNVTIAHCPSSNLKLGSGIAPLKAMLKYEINVTIGTDGAASNNNLNMIEEVNLAALLHKG
VNKDPLFLSPKEIIKISSLNGAKAQGRKDCGSIKIGNRADIVIYDFNKPHMKPIHDVLANLIYSAQSDDICLTIIDGNIV
YKDGTFTNIDIEKVYYNINRIKNQKLKMVSNIGNNII

Sequences:

>Translated_437_residues
MLIKNITLIDENYDVIENSNIVIEENVISYIGKDIPQNYADYIYDGKNKVAVPGLFNMHCHVPMTLVRGYGEGLPLNRWL
SEKIWPFEYFLTDEDCYYGSLLGISEMIKSGVVSFNDMYFNLEGILKAVYETGIKANLSYGYVDTPENQDYFKGNAYKQT
KMLNDYIKNTNTDRIKADVSIHAVYTSSEDSVRKISEYCNSTKMNMHIHLSETELEIKECKKRFGVTPVEYFLNCGTFKS
NTIAAHCVHLEDDDFSILKENNVTIAHCPSSNLKLGSGIAPLKAMLKYEINVTIGTDGAASNNNLNMIEEVNLAALLHKG
VNKDPLFLSPKEIIKISSLNGAKAQGRKDCGSIKIGNRADIVIYDFNKPHMKPIHDVLANLIYSAQSDDICLTIIDGNIV
YKDGTFTNIDIEKVYYNINRIKNQKLKMVSNIGNNII
>Mature_437_residues
MLIKNITLIDENYDVIENSNIVIEENVISYIGKDIPQNYADYIYDGKNKVAVPGLFNMHCHVPMTLVRGYGEGLPLNRWL
SEKIWPFEYFLTDEDCYYGSLLGISEMIKSGVVSFNDMYFNLEGILKAVYETGIKANLSYGYVDTPENQDYFKGNAYKQT
KMLNDYIKNTNTDRIKADVSIHAVYTSSEDSVRKISEYCNSTKMNMHIHLSETELEIKECKKRFGVTPVEYFLNCGTFKS
NTIAAHCVHLEDDDFSILKENNVTIAHCPSSNLKLGSGIAPLKAMLKYEINVTIGTDGAASNNNLNMIEEVNLAALLHKG
VNKDPLFLSPKEIIKISSLNGAKAQGRKDCGSIKIGNRADIVIYDFNKPHMKPIHDVLANLIYSAQSDDICLTIIDGNIV
YKDGTFTNIDIEKVYYNINRIKNQKLKMVSNIGNNII

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=383, Percent_Identity=23.7597911227154, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI87082177, Length=436, Percent_Identity=24.0825688073394, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789249, Length=439, Percent_Identity=27.1070615034169, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17540282, Length=381, Percent_Identity=23.3595800524934, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6319963, Length=361, Percent_Identity=24.3767313019391, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643849, Length=385, Percent_Identity=23.6363636363636, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 49254; Mature: 49254

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKNITLIDENYDVIENSNIVIEENVISYIGKDIPQNYADYIYDGKNKVAVPGLFNMHC
CEEEEEEEEECCCCEEECCCEEEEHHHHHHHHHHCCCCHHHHEECCCCCEECCCEEEEEE
HVPMTLVRGYGEGLPLNRWLSEKIWPFEYFLTDEDCYYGSLLGISEMIKSGVVSFNDMYF
CCHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEHEEE
NLEGILKAVYETGIKANLSYGYVDTPENQDYFKGNAYKQTKMLNDYIKNTNTDRIKADVS
EHHHHHHHHHHCCCEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEE
IHAVYTSSEDSVRKISEYCNSTKMNMHIHLSETELEIKECKKRFGVTPVEYFLNCGTFKS
EEEEEECCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCHHHHHHCCCCCCC
NTIAAHCVHLEDDDFSILKENNVTIAHCPSSNLKLGSGIAPLKAMLKYEINVTIGTDGAA
CCEEEEEEEECCCCCEEEECCCEEEEECCCCCCCCCCCCHHHHEEEEEEEEEEECCCCCC
SNNNLNMIEEVNLAALLHKGVNKDPLFLSPKEIIKISSLNGAKAQGRKDCGSIKIGNRAD
CCCCCCHHHHHHHHHHHHCCCCCCCCEECHHHHEEEECCCCCCCCCCCCCCCEEECCCEE
IVIYDFNKPHMKPIHDVLANLIYSAQSDDICLTIIDGNIVYKDGTFTNIDIEKVYYNINR
EEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCEEEEEHHHEEEEHHH
IKNQKLKMVSNIGNNII
HCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MLIKNITLIDENYDVIENSNIVIEENVISYIGKDIPQNYADYIYDGKNKVAVPGLFNMHC
CEEEEEEEEECCCCEEECCCEEEEHHHHHHHHHHCCCCHHHHEECCCCCEECCCEEEEEE
HVPMTLVRGYGEGLPLNRWLSEKIWPFEYFLTDEDCYYGSLLGISEMIKSGVVSFNDMYF
CCHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEHEEE
NLEGILKAVYETGIKANLSYGYVDTPENQDYFKGNAYKQTKMLNDYIKNTNTDRIKADVS
EHHHHHHHHHHCCCEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEE
IHAVYTSSEDSVRKISEYCNSTKMNMHIHLSETELEIKECKKRFGVTPVEYFLNCGTFKS
EEEEEECCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCHHHHHHCCCCCCC
NTIAAHCVHLEDDDFSILKENNVTIAHCPSSNLKLGSGIAPLKAMLKYEINVTIGTDGAA
CCEEEEEEEECCCCCEEEECCCEEEEECCCCCCCCCCCCHHHHEEEEEEEEEEECCCCCC
SNNNLNMIEEVNLAALLHKGVNKDPLFLSPKEIIKISSLNGAKAQGRKDCGSIKIGNRAD
CCCCCCHHHHHHHHHHHHCCCCCCCCEECHHHHEEEECCCCCCCCCCCCCCCEEECCCEE
IVIYDFNKPHMKPIHDVLANLIYSAQSDDICLTIIDGNIVYKDGTFTNIDIEKVYYNINR
EEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCEEEEEHHHEEEEHHH
IKNQKLKMVSNIGNNII
HCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA