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The map label for this gene is oxc [H]

Identifier: 170751953

GI number: 170751953

Start: 5906358

End: 5908103

Strand: Reverse

Name: oxc [H]

Synonym: Mrad2831_5585

Alternate gene names: 170751953

Gene position: 5908103-5906358 (Counterclockwise)

Preceding gene: 170751954

Following gene: 170751952

Centisome position: 97.21

GC content: 69.13

Gene sequence:

>1746_bases
ATGACCGCAGTCGCCAAGATCGTCCACACCGCCCCCGAGGTCGAGGCCGAGCCCGATCTGACCGACGGCTTCCACCTCGT
CATCGACGCGCTCAAGCTCAACGGCATCGACACCATCTACGGTGTCCCGGGCATCCCGATCACCGATCTCGGCCGCATGG
CCCAGGCCGAGGGGATGCGGGTCATCTCGTTCCGCCACGAGCAGCACGCCGGTAACGCCGCGGCGATCGCGGGCTTCCTC
ACCCAGAAGCCGGGCATCTGCCTCACCGTCTCGGCGCCGGGCTTCCTCAACGGCCTGACCGCCCTCGCCAACGCCACCAC
CAACTGCTTCCCGATGATCCTGATCTCGGGCTCCTCCGAGCGCGAGATCGTCGACCTGCAGCAGGGCGACTACGAGGAGA
TGGACCAGCTCGCCATCGCCAAGCCCCTGTGCAAGGCGGCCTTCCGCGTCCTGCACGCCGCCGATATCGGCATCGGCGTC
GCCCGCGCGATCCGCGCGGCCTGCTCGGGCCGGCCGGGCGGCGTCTACCTCGACCTGCCCGCCAAGCTGTTCTCCCAGGT
GATGGACGCCGAGGCCGGCCAGAAGTCGCTGGTCAAGGTGATCGACCCGGCCCCGGCCCAGCACCCCGCCCCCGAGGCGA
TCGCCCGGGCGCTCGAGGTCCTGAAATCCGCCAAGCGGCCGCTGATCGTGCTCGGCAAGGGCGCCGCCTACGCCCAGGCC
GACGAGGCGATCCGCGCCCTCGTGGAGACGAGCGGCATCCCCTACGTTCCGATGAGCATGGCCAAGGGCCTCCTGCCCGA
CACCCACCCGCTCTCGGCCGGCGCGGCGCGCTCGACGGCGCTGAAGGACTCGGACGTGGTGCTGCTGATCGGCGCCCGGC
TGAACTGGCTGCTGTCGCACGGCAAGGGCAAGAGCTGGGGCGAGCCGGGCTCGACCAAGTTCATCCAGATCGACATCGAG
CCCCGCGAGATGGACTCGAACGTCGAGATCGTCGCTCCGGTGGTCGGCGACATCGCCTCCTGCGTCCAGGCACTGCTCGA
CGGCATGGGCCAGGGCTGGCAGCAGCCCCCGTCCGACTGGATCGAGACGCTCAAGACCAAGCGCGAGGCGAACATCGCCA
AGATGGCTCCGAAGCTCATGAGCAACGCCTCGCCCATGAATTTCCACGCCGCGCTCGGGGCGCTCCGCACCATCATCAAG
GAGCGGCCGGACGCGATCCTGGTCAACGAGGGCGCCAACACCCTCGACCTCGCCCGCGGCATCATCGACATGTACCAGCC
GCGCAAGCGCCTGGACGTCGGCACCTGGGGCATCATGGGCATCGGCATGGGCTTCGCCGTCGCGGCCGCGGTCGAGACCG
GCAAGCCGGTCCTCTGCGTGGAAGGCGACAGCGCCTTCGGCTTCTCCGGCATGGAGGTCGAGACGATCTGCCGGTACGGC
CTGCCGGTCTGCATCGTGGTGTTCAACAACAACGGCATCTATCGCGGCACCGACACCGACCCGACCGGTCGCGATCCGGC
CACCACGGTGTTCGTGCCGGATTCCCGCTACGACCGGATGATCGAGGCCTTCGGCGGCGTCGGCTACCACGTCACCACGC
CCGACGAGCTGACCCGCGCGGTCAACGAGGCGATGAACTCGGGCCGCCCGGCCCTGGTCAACGCCGTCATCGACCCGGCC
GCCGGCAGCGAGAGCGGCAACATCGGCAGCCTCAACCCCCAGAGCGGGATCAAGAAGAAGAAGTGA

Upstream 100 bases:

>100_bases
CCGGATCTCCCGCCCGCCCCGTCTTCGGGAGCGCGGGGGATCCCCAGCCAGCCGGCGCCGAGCGCCGCCCGTCCAAACCG
ATCTTCCGGGAGAAACCGTG

Downstream 100 bases:

>100_bases
GGGCCGCGGGCGTCCTCAGCCCGATCCCCTGACGTCGACAGACCGGCCGGATCGCTCAGCGGTCCGGCCGTTCGTGAATG
AGCGGCATCCTCTCAGGCCG

Product: putative oxalyl-CoA decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MTAVAKIVHTAPEVEAEPDLTDGFHLVIDALKLNGIDTIYGVPGIPITDLGRMAQAEGMRVISFRHEQHAGNAAAIAGFL
TQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGV
ARAIRAACSGRPGGVYLDLPAKLFSQVMDAEAGQKSLVKVIDPAPAQHPAPEAIARALEVLKSAKRPLIVLGKGAAYAQA
DEAIRALVETSGIPYVPMSMAKGLLPDTHPLSAGAARSTALKDSDVVLLIGARLNWLLSHGKGKSWGEPGSTKFIQIDIE
PREMDSNVEIVAPVVGDIASCVQALLDGMGQGWQQPPSDWIETLKTKREANIAKMAPKLMSNASPMNFHAALGALRTIIK
ERPDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGIMGIGMGFAVAAAVETGKPVLCVEGDSAFGFSGMEVETICRYG
LPVCIVVFNNNGIYRGTDTDPTGRDPATTVFVPDSRYDRMIEAFGGVGYHVTTPDELTRAVNEAMNSGRPALVNAVIDPA
AGSESGNIGSLNPQSGIKKKK

Sequences:

>Translated_581_residues
MTAVAKIVHTAPEVEAEPDLTDGFHLVIDALKLNGIDTIYGVPGIPITDLGRMAQAEGMRVISFRHEQHAGNAAAIAGFL
TQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGV
ARAIRAACSGRPGGVYLDLPAKLFSQVMDAEAGQKSLVKVIDPAPAQHPAPEAIARALEVLKSAKRPLIVLGKGAAYAQA
DEAIRALVETSGIPYVPMSMAKGLLPDTHPLSAGAARSTALKDSDVVLLIGARLNWLLSHGKGKSWGEPGSTKFIQIDIE
PREMDSNVEIVAPVVGDIASCVQALLDGMGQGWQQPPSDWIETLKTKREANIAKMAPKLMSNASPMNFHAALGALRTIIK
ERPDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGIMGIGMGFAVAAAVETGKPVLCVEGDSAFGFSGMEVETICRYG
LPVCIVVFNNNGIYRGTDTDPTGRDPATTVFVPDSRYDRMIEAFGGVGYHVTTPDELTRAVNEAMNSGRPALVNAVIDPA
AGSESGNIGSLNPQSGIKKKK
>Mature_580_residues
TAVAKIVHTAPEVEAEPDLTDGFHLVIDALKLNGIDTIYGVPGIPITDLGRMAQAEGMRVISFRHEQHAGNAAAIAGFLT
QKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVA
RAIRAACSGRPGGVYLDLPAKLFSQVMDAEAGQKSLVKVIDPAPAQHPAPEAIARALEVLKSAKRPLIVLGKGAAYAQAD
EAIRALVETSGIPYVPMSMAKGLLPDTHPLSAGAARSTALKDSDVVLLIGARLNWLLSHGKGKSWGEPGSTKFIQIDIEP
REMDSNVEIVAPVVGDIASCVQALLDGMGQGWQQPPSDWIETLKTKREANIAKMAPKLMSNASPMNFHAALGALRTIIKE
RPDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGIMGIGMGFAVAAAVETGKPVLCVEGDSAFGFSGMEVETICRYGL
PVCIVVFNNNGIYRGTDTDPTGRDPATTVFVPDSRYDRMIEAFGGVGYHVTTPDELTRAVNEAMNSGRPALVNAVIDPAA
GSESGNIGSLNPQSGIKKKK

Specific function: Oxalic acid catabolism; second step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Homo sapiens, GI93004078, Length=574, Percent_Identity=39.3728222996516, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI21361361, Length=571, Percent_Identity=29.2469352014011, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1788716, Length=557, Percent_Identity=60.3231597845601, Blast_Score=672, Evalue=0.0,
Organism=Escherichia coli, GI87081685, Length=565, Percent_Identity=26.3716814159292, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1790104, Length=483, Percent_Identity=27.536231884058, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1786717, Length=489, Percent_Identity=27.8118609406953, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787096, Length=556, Percent_Identity=23.7410071942446, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17531301, Length=551, Percent_Identity=37.9310344827586, Blast_Score=352, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17531299, Length=551, Percent_Identity=37.9310344827586, Blast_Score=351, Evalue=7e-97,
Organism=Caenorhabditis elegans, GI17542570, Length=594, Percent_Identity=28.4511784511784, Blast_Score=201, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320816, Length=545, Percent_Identity=35.2293577981651, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6323755, Length=585, Percent_Identity=22.2222222222222, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19922626, Length=563, Percent_Identity=39.6092362344583, Blast_Score=405, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017660
- InterPro:   IPR012000
- InterPro:   IPR012001
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF00205 TPP_enzyme_M; PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.8 [H]

Molecular weight: Translated: 61398; Mature: 61267

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAKIVHTAPEVEAEPDLTDGFHLVIDALKLNGIDTIYGVPGIPITDLGRMAQAEGMR
CCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCE
VISFRHEQHAGNAAAIAGFLTQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSE
EEEEECHHCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCC
REIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAACSGRPGGVYLDLP
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECH
AKLFSQVMDAEAGQKSLVKVIDPAPAQHPAPEAIARALEVLKSAKRPLIVLGKGAAYAQA
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
DEAIRALVETSGIPYVPMSMAKGLLPDTHPLSAGAARSTALKDSDVVLLIGARLNWLLSH
HHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHCCCCCCCEEEEECCHHHHHHHC
GKGKSWGEPGSTKFIQIDIEPREMDSNVEIVAPVVGDIASCVQALLDGMGQGWQQPPSDW
CCCCCCCCCCCCEEEEEEECHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IETLKTKREANIAKMAPKLMSNASPMNFHAALGALRTIIKERPDAILVNEGANTLDLARG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
IIDMYQPRKRLDVGTWGIMGIGMGFAVAAAVETGKPVLCVEGDSAFGFSGMEVETICRYG
HHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCC
LPVCIVVFNNNGIYRGTDTDPTGRDPATTVFVPDSRYDRMIEAFGGVGYHVTTPDELTRA
CCEEEEEECCCCEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCEEECCHHHHHHH
VNEAMNSGRPALVNAVIDPAAGSESGNIGSLNPQSGIKKKK
HHHHHHCCCCEEEHEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAVAKIVHTAPEVEAEPDLTDGFHLVIDALKLNGIDTIYGVPGIPITDLGRMAQAEGMR
CHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCE
VISFRHEQHAGNAAAIAGFLTQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSE
EEEEECHHCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCC
REIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAACSGRPGGVYLDLP
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECH
AKLFSQVMDAEAGQKSLVKVIDPAPAQHPAPEAIARALEVLKSAKRPLIVLGKGAAYAQA
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
DEAIRALVETSGIPYVPMSMAKGLLPDTHPLSAGAARSTALKDSDVVLLIGARLNWLLSH
HHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHCCCCCCCEEEEECCHHHHHHHC
GKGKSWGEPGSTKFIQIDIEPREMDSNVEIVAPVVGDIASCVQALLDGMGQGWQQPPSDW
CCCCCCCCCCCCEEEEEEECHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IETLKTKREANIAKMAPKLMSNASPMNFHAALGALRTIIKERPDAILVNEGANTLDLARG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
IIDMYQPRKRLDVGTWGIMGIGMGFAVAAAVETGKPVLCVEGDSAFGFSGMEVETICRYG
HHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCC
LPVCIVVFNNNGIYRGTDTDPTGRDPATTVFVPDSRYDRMIEAFGGVGYHVTTPDELTRA
CCEEEEEECCCCEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCEEECCHHHHHHH
VNEAMNSGRPALVNAVIDPAAGSESGNIGSLNPQSGIKKKK
HHHHHHCCCCEEEHEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157618 [H]