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The map label for this gene is oxlT [H]

Identifier: 170751954

GI number: 170751954

Start: 5908249

End: 5909535

Strand: Reverse

Name: oxlT [H]

Synonym: Mrad2831_5586

Alternate gene names: 170751954

Gene position: 5909535-5908249 (Counterclockwise)

Preceding gene: 170751955

Following gene: 170751953

Centisome position: 97.23

GC content: 68.07

Gene sequence:

>1287_bases
ATGGAACGCCAGGATTCGCCGTCGGCGAAATGGTGGCAGCTCGCCTTCGGCGTGATCTGCATGGCCATGATCGCCAACCT
CCAATACGGTTGGACACTGTTCGTGGACCCGATCGATCAGCGTTACCACTGGGGCCGCGCGGCGATCCAGCTCGCATTCA
CGCTGTTCGTCGCCACCGAGACCTGGCTGGTTCCGGTCGAGGCTTGGTTCGTCGACCGCTACGGTCCGAAGATCGTGGTC
GCCTTCGGCGGCGTGATGATCGCCCTCGCCTGGACCATCAACGCGTACGCCGACAGCCTGGCGATGCTCTATCTCGGCGC
CGTCATCGCCGGCATCGGAGCGGGCTCGGTCTACGGCACCTGTGTGGGCAACGCGCTCAAGTGGTTCCCGGATCGCCGCG
GCCTCGCCGCCGGTGCCACCGCGGCCGGCTTCGGCGCGGGTGCCGCCATCACGGTGGTGCCGATCGCCCGCATGATCGCG
TCCAGCGGCTACCAGGACGCATTCCTGTATTTCGGCATCGGCCAGGGCGCCGTGGTCCTCGCCCTCGCCTTCCTGCTGCG
CAAGCCGTCGACCAACACGCCGGTCCAGCGCAAGAAGACGCGCCTGCCGCAGACCAAGGTCGACCGCAGCCCGCGCGAGG
CGGTGCGCACCCCGGTCTTCTGGGTGATGTACGTGATGTTCGTGATGGTCGCCTCCGGTGGCCTGATGGCGGCGGCGCAG
ATCGCCCCGATCGCCCATGACTTCCAGGTGGCCGGCGTCCCGGTGAGCCTGTTCGGCCTGCAGATGGCGGCGCTGACGCT
GGCGATCTCGCTCGACCGGGTCTTCGACGGGTTCGGCCGGCCGTTCTTCGGCTACGTCTCCGACCATATCGGCCGCGAGA
ACACGATGTTCATCGCCTTTTCGACGGCGGCGCTGGCCGTGATCGTGCTGCTGACCTACGGCCACATCCCGATGGTCTTC
GTGTTGGCCACCGCGGTGTATTTCGGGGTGTTCGGCGAGATCTACTCGCTGTTCCCGGCGACCTGCGGCGACACGTTCGG
CTCCAAGTACGCCGCCAGCAACGCCGGCCTGCTCTACACCGCCAAGGGTACCGCGGCCTTCCTCGTCCCCTTCGCCAGCA
TCCTGTCGGCGGCCTACGGCTGGTCGGCGGTGTTCACGCTGATCATCGTCCTCAACGTGACGGCGGCGGCGCTGGCGATG
TTCGTCCTGCGCCCGATGCGGGCCCGCTACCTCGCCTCGGAAGACCAGCCCGCGGCGCTCGGCGCCCAGCCGATCCGGGC
GGCCTGA

Upstream 100 bases:

>100_bases
ACGCTGGTATATTGCATACCTAGAACGGATGTGCATGATCGTCGGTGCACCAGAGACGCCGCCACAGCAAGGCCGCGCCG
CCCAAGAGAGAGGCTCAGGG

Downstream 100 bases:

>100_bases
CCGGCCTCCCACCCCACGGCGTCGCGGAAGCGACGCCCAACCTTCCCGGATCTCCCGCCCGCCCCGTCTTCGGGAGCGCG
GGGGATCCCCAGCCAGCCGG

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MERQDSPSAKWWQLAFGVICMAMIANLQYGWTLFVDPIDQRYHWGRAAIQLAFTLFVATETWLVPVEAWFVDRYGPKIVV
AFGGVMIALAWTINAYADSLAMLYLGAVIAGIGAGSVYGTCVGNALKWFPDRRGLAAGATAAGFGAGAAITVVPIARMIA
SSGYQDAFLYFGIGQGAVVLALAFLLRKPSTNTPVQRKKTRLPQTKVDRSPREAVRTPVFWVMYVMFVMVASGGLMAAAQ
IAPIAHDFQVAGVPVSLFGLQMAALTLAISLDRVFDGFGRPFFGYVSDHIGRENTMFIAFSTAALAVIVLLTYGHIPMVF
VLATAVYFGVFGEIYSLFPATCGDTFGSKYAASNAGLLYTAKGTAAFLVPFASILSAAYGWSAVFTLIIVLNVTAAALAM
FVLRPMRARYLASEDQPAALGAQPIRAA

Sequences:

>Translated_428_residues
MERQDSPSAKWWQLAFGVICMAMIANLQYGWTLFVDPIDQRYHWGRAAIQLAFTLFVATETWLVPVEAWFVDRYGPKIVV
AFGGVMIALAWTINAYADSLAMLYLGAVIAGIGAGSVYGTCVGNALKWFPDRRGLAAGATAAGFGAGAAITVVPIARMIA
SSGYQDAFLYFGIGQGAVVLALAFLLRKPSTNTPVQRKKTRLPQTKVDRSPREAVRTPVFWVMYVMFVMVASGGLMAAAQ
IAPIAHDFQVAGVPVSLFGLQMAALTLAISLDRVFDGFGRPFFGYVSDHIGRENTMFIAFSTAALAVIVLLTYGHIPMVF
VLATAVYFGVFGEIYSLFPATCGDTFGSKYAASNAGLLYTAKGTAAFLVPFASILSAAYGWSAVFTLIIVLNVTAAALAM
FVLRPMRARYLASEDQPAALGAQPIRAA
>Mature_428_residues
MERQDSPSAKWWQLAFGVICMAMIANLQYGWTLFVDPIDQRYHWGRAAIQLAFTLFVATETWLVPVEAWFVDRYGPKIVV
AFGGVMIALAWTINAYADSLAMLYLGAVIAGIGAGSVYGTCVGNALKWFPDRRGLAAGATAAGFGAGAAITVVPIARMIA
SSGYQDAFLYFGIGQGAVVLALAFLLRKPSTNTPVQRKKTRLPQTKVDRSPREAVRTPVFWVMYVMFVMVASGGLMAAAQ
IAPIAHDFQVAGVPVSLFGLQMAALTLAISLDRVFDGFGRPFFGYVSDHIGRENTMFIAFSTAALAVIVLLTYGHIPMVF
VLATAVYFGVFGEIYSLFPATCGDTFGSKYAASNAGLLYTAKGTAAFLVPFASILSAAYGWSAVFTLIIVLNVTAAALAM
FVLRPMRARYLASEDQPAALGAQPIRAA

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=381, Percent_Identity=23.8845144356955, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45884; Mature: 45884

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERQDSPSAKWWQLAFGVICMAMIANLQYGWTLFVDPIDQRYHWGRAAIQLAFTLFVATE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHC
TWLVPVEAWFVDRYGPKIVVAFGGVMIALAWTINAYADSLAMLYLGAVIAGIGAGSVYGT
CEEEEHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CVGNALKWFPDRRGLAAGATAAGFGAGAAITVVPIARMIASSGYQDAFLYFGIGQGAVVL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHH
ALAFLLRKPSTNTPVQRKKTRLPQTKVDRSPREAVRTPVFWVMYVMFVMVASGGLMAAAQ
HHHHHHHCCCCCCCHHHHHHCCCHHHCCCCHHHHHHCHHHHHHHHHHHHHHCCCCHHHHH
IAPIAHDFQVAGVPVSLFGLQMAALTLAISLDRVFDGFGRPFFGYVSDHIGRENTMFIAF
HCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEE
STAALAVIVLLTYGHIPMVFVLATAVYFGVFGEIYSLFPATCGDTFGSKYAASNAGLLYT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCEEEE
AKGTAAFLVPFASILSAAYGWSAVFTLIIVLNVTAAALAMFVLRPMRARYLASEDQPAAL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GAQPIRAA
CCCCCCCC
>Mature Secondary Structure
MERQDSPSAKWWQLAFGVICMAMIANLQYGWTLFVDPIDQRYHWGRAAIQLAFTLFVATE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHC
TWLVPVEAWFVDRYGPKIVVAFGGVMIALAWTINAYADSLAMLYLGAVIAGIGAGSVYGT
CEEEEHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CVGNALKWFPDRRGLAAGATAAGFGAGAAITVVPIARMIASSGYQDAFLYFGIGQGAVVL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHH
ALAFLLRKPSTNTPVQRKKTRLPQTKVDRSPREAVRTPVFWVMYVMFVMVASGGLMAAAQ
HHHHHHHCCCCCCCHHHHHHCCCHHHCCCCHHHHHHCHHHHHHHHHHHHHHCCCCHHHHH
IAPIAHDFQVAGVPVSLFGLQMAALTLAISLDRVFDGFGRPFFGYVSDHIGRENTMFIAF
HCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEE
STAALAVIVLLTYGHIPMVFVLATAVYFGVFGEIYSLFPATCGDTFGSKYAASNAGLLYT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCEEEE
AKGTAAFLVPFASILSAAYGWSAVFTLIIVLNVTAAALAMFVLRPMRARYLASEDQPAAL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GAQPIRAA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]