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The map label for this gene is yyaJ [H]

Identifier: 170751864

GI number: 170751864

Start: 5809449

End: 5810921

Strand: Reverse

Name: yyaJ [H]

Synonym: Mrad2831_5496

Alternate gene names: 170751864

Gene position: 5810921-5809449 (Counterclockwise)

Preceding gene: 170751867

Following gene: 170751860

Centisome position: 95.61

GC content: 69.11

Gene sequence:

>1473_bases
ATGGCGAGCAAGGTCGAGGGGGGATCCGGGACGCCGGAACGCGCGGAGATCGGCCGCGTGATCGACACCGACATCTCCGC
GCGCCTGGACCGGCTGCCCTGGGGCCGCTTCCACGTACTGGTGATCGTGGCGCTCGGCATCACCTGGGTGCTGGACGGCC
TCGAAGTGACGCTCGCCGGCTCCCTGGTGGGCGCGCTGCGCCAGCCGCCCATGTCGTTCTCGGAGTTCGACGTCGGGCTC
GCCGCCTCCTGCTACCTCGTGGGCGCCGTCACCGGCGCGATCGGCTTCGGCTGGCTCACCGACCGGATCGGCCGCAAGAA
GCTGTTCTTCATCACGCTCGCCCTCTACCTCGTCGCCACGGCCGCCACCGGCCTGTCGTGGAACATCTGGACCTTCTGCT
TCTTCCGCTTCCTCACGGGCGCGGGGATCGGCGGCGAGTACACGGCGATCAACTCGACCATCCAGGAGCTGGTCCCGGCC
CGGGTCCGCGGGTGGACCAACCTCGTCATCAACGGCTCGTTCTGGATCGGCGCGGCGCTCGGCTCGTTCATGTCGATCGT
GCTCCTCAAGCCCGAGGTGATCGACCCAGCCTGGGGCTGGCGCGTCGCCTTCTTCACCGGCGGCGCCATCGGCCTCGTGA
TCCTCCTCCTGCGCACCTGGATCCCCGAGAGCCCGCGCTGGCTCGCCACCCACGGCTACGCGGCGGAAGCCGACCGGGTC
GTCACCGGCATCGAGAAGCGCTTCACCGACGAGGGCGTCACCCTGCCGCCGGTGGACGAGAGCAAGCGCATGAAGGTCCG
CACCCGCGACCACACACCGCTCTCCGAGGTGTTCAAGGCGCTGTTCGTGACGAGCCGCAAGGAGACCATGGTCGGTCTCG
CACTGATGATCGCGCAGGCCTTCTTCTACAACGCCCTGTTCTTCACATACGCGCTGGTGCTGGAGCGCTTTTACCAGGTC
CCCGGCAACCATGTCGGCTGGTACCTGCTGCCCTTCGCGCTCGGCTCGTTCCTCGGCCCGCTGCTCCTCGGGCGGCTCTT
CGACACGATCGGACGGCGCAAGATGATCGCCTTCACGTACGGCATCTCGGCGCTGCTGCTCGCCGGTGTCGGCCTGCTGT
TCCGCCTCGACGTGCTCGGGCCGGTCGGCCAGACCGCGGCCTGGATGGTGGTGTTCTTCTTCGCCTCGGCGGCGGCGAGC
TCGGCCTATCTCACGGTCTCGGAGACCTTCCCGCTGGAGATCCGGGCCCTGGCGATCGCGGCCTTCTACGCGGTCGGCAC
CGGTATCGGCGGCGTCTCGGGCCCGCTCCTGTTCGGCACGCTGGTCGAGACCGGCTCGCGCGACTGGGTGCTGTTCGGCT
ACGGCCTCGGCGCTGTGCTGATGCTCATCGCGGCGGTGGTCGGAGGCATCTGGGGAACGGCCGCGGAGGGCAAGTCCCTG
GAGGAGGTGTCGAAGCCGCTGGCAGCGGCCTGA

Upstream 100 bases:

>100_bases
CCGAATCGATTTCCAACCCGTTCCCAACACCTGCCTACAGTCGCGGTAAATGCCGGCTGTCTCAGCAGGGTAAACACTTG
GACCGGGAGGATACGCGGAC

Downstream 100 bases:

>100_bases
GGGCAGGCCCGCGGCGACAGCCGTCCGCGCGGGCGGAGCGAGGCCGCCGGGCCTCGCGCCGCACAGCGCTCGCCGTCGCG
GTCCGTCACGTTTCCCTGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MASKVEGGSGTPERAEIGRVIDTDISARLDRLPWGRFHVLVIVALGITWVLDGLEVTLAGSLVGALRQPPMSFSEFDVGL
AASCYLVGAVTGAIGFGWLTDRIGRKKLFFITLALYLVATAATGLSWNIWTFCFFRFLTGAGIGGEYTAINSTIQELVPA
RVRGWTNLVINGSFWIGAALGSFMSIVLLKPEVIDPAWGWRVAFFTGGAIGLVILLLRTWIPESPRWLATHGYAAEADRV
VTGIEKRFTDEGVTLPPVDESKRMKVRTRDHTPLSEVFKALFVTSRKETMVGLALMIAQAFFYNALFFTYALVLERFYQV
PGNHVGWYLLPFALGSFLGPLLLGRLFDTIGRRKMIAFTYGISALLLAGVGLLFRLDVLGPVGQTAAWMVVFFFASAAAS
SAYLTVSETFPLEIRALAIAAFYAVGTGIGGVSGPLLFGTLVETGSRDWVLFGYGLGAVLMLIAAVVGGIWGTAAEGKSL
EEVSKPLAAA

Sequences:

>Translated_490_residues
MASKVEGGSGTPERAEIGRVIDTDISARLDRLPWGRFHVLVIVALGITWVLDGLEVTLAGSLVGALRQPPMSFSEFDVGL
AASCYLVGAVTGAIGFGWLTDRIGRKKLFFITLALYLVATAATGLSWNIWTFCFFRFLTGAGIGGEYTAINSTIQELVPA
RVRGWTNLVINGSFWIGAALGSFMSIVLLKPEVIDPAWGWRVAFFTGGAIGLVILLLRTWIPESPRWLATHGYAAEADRV
VTGIEKRFTDEGVTLPPVDESKRMKVRTRDHTPLSEVFKALFVTSRKETMVGLALMIAQAFFYNALFFTYALVLERFYQV
PGNHVGWYLLPFALGSFLGPLLLGRLFDTIGRRKMIAFTYGISALLLAGVGLLFRLDVLGPVGQTAAWMVVFFFASAAAS
SAYLTVSETFPLEIRALAIAAFYAVGTGIGGVSGPLLFGTLVETGSRDWVLFGYGLGAVLMLIAAVVGGIWGTAAEGKSL
EEVSKPLAAA
>Mature_489_residues
ASKVEGGSGTPERAEIGRVIDTDISARLDRLPWGRFHVLVIVALGITWVLDGLEVTLAGSLVGALRQPPMSFSEFDVGLA
ASCYLVGAVTGAIGFGWLTDRIGRKKLFFITLALYLVATAATGLSWNIWTFCFFRFLTGAGIGGEYTAINSTIQELVPAR
VRGWTNLVINGSFWIGAALGSFMSIVLLKPEVIDPAWGWRVAFFTGGAIGLVILLLRTWIPESPRWLATHGYAAEADRVV
TGIEKRFTDEGVTLPPVDESKRMKVRTRDHTPLSEVFKALFVTSRKETMVGLALMIAQAFFYNALFFTYALVLERFYQVP
GNHVGWYLLPFALGSFLGPLLLGRLFDTIGRRKMIAFTYGISALLLAGVGLLFRLDVLGPVGQTAAWMVVFFFASAAASS
AYLTVSETFPLEIRALAIAAFYAVGTGIGGVSGPLLFGTLVETGSRDWVLFGYGLGAVLMLIAAVVGGIWGTAAEGKSLE
EVSKPLAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=267, Percent_Identity=24.7191011235955, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI166197673, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI4506999, Length=401, Percent_Identity=24.4389027431421, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI24308167, Length=513, Percent_Identity=21.6374269005848, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI23510410, Length=236, Percent_Identity=26.271186440678, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1788068, Length=485, Percent_Identity=27.4226804123711, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87082159, Length=443, Percent_Identity=25.5079006772009, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786229, Length=424, Percent_Identity=25.9433962264151, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788074, Length=455, Percent_Identity=25.9340659340659, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790550, Length=420, Percent_Identity=24.7619047619048, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081723, Length=382, Percent_Identity=24.6073298429319, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789312, Length=348, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=488, Percent_Identity=23.155737704918, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565976, Length=306, Percent_Identity=24.1830065359477, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986689, Length=270, Percent_Identity=23.7037037037037, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193202825, Length=270, Percent_Identity=23.7037037037037, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320766, Length=366, Percent_Identity=24.0437158469945, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324400, Length=364, Percent_Identity=23.9010989010989, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320552, Length=375, Percent_Identity=24, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330907, Length=367, Percent_Identity=24.2506811989101, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922874, Length=453, Percent_Identity=23.3995584988962, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922616, Length=363, Percent_Identity=23.1404958677686, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24648211, Length=382, Percent_Identity=21.9895287958115, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52793; Mature: 52662

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKVEGGSGTPERAEIGRVIDTDISARLDRLPWGRFHVLVIVALGITWVLDGLEVTLAG
CCCCCCCCCCCCCHHHHCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
SLVGALRQPPMSFSEFDVGLAASCYLVGAVTGAIGFGWLTDRIGRKKLFFITLALYLVAT
HHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AATGLSWNIWTFCFFRFLTGAGIGGEYTAINSTIQELVPARVRGWTNLVINGSFWIGAAL
HHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHH
GSFMSIVLLKPEVIDPAWGWRVAFFTGGAIGLVILLLRTWIPESPRWLATHGYAAEADRV
HHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHH
VTGIEKRFTDEGVTLPPVDESKRMKVRTRDHTPLSEVFKALFVTSRKETMVGLALMIAQA
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FFYNALFFTYALVLERFYQVPGNHVGWYLLPFALGSFLGPLLLGRLFDTIGRRKMIAFTY
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
GISALLLAGVGLLFRLDVLGPVGQTAAWMVVFFFASAAASSAYLTVSETFPLEIRALAIA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
AFYAVGTGIGGVSGPLLFGTLVETGSRDWVLFGYGLGAVLMLIAAVVGGIWGTAAEGKSL
HHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCH
EEVSKPLAAA
HHHHHHHCCC
>Mature Secondary Structure 
ASKVEGGSGTPERAEIGRVIDTDISARLDRLPWGRFHVLVIVALGITWVLDGLEVTLAG
CCCCCCCCCCCCHHHHCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
SLVGALRQPPMSFSEFDVGLAASCYLVGAVTGAIGFGWLTDRIGRKKLFFITLALYLVAT
HHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AATGLSWNIWTFCFFRFLTGAGIGGEYTAINSTIQELVPARVRGWTNLVINGSFWIGAAL
HHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHH
GSFMSIVLLKPEVIDPAWGWRVAFFTGGAIGLVILLLRTWIPESPRWLATHGYAAEADRV
HHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHH
VTGIEKRFTDEGVTLPPVDESKRMKVRTRDHTPLSEVFKALFVTSRKETMVGLALMIAQA
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FFYNALFFTYALVLERFYQVPGNHVGWYLLPFALGSFLGPLLLGRLFDTIGRRKMIAFTY
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
GISALLLAGVGLLFRLDVLGPVGQTAAWMVVFFFASAAASSAYLTVSETFPLEIRALAIA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
AFYAVGTGIGGVSGPLLFGTLVETGSRDWVLFGYGLGAVLMLIAAVVGGIWGTAAEGKSL
HHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCH
EEVSKPLAAA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]