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The map label for this gene is ltrA [H]

Identifier: 170751867

GI number: 170751867

Start: 5812425

End: 5813318

Strand: Reverse

Name: ltrA [H]

Synonym: Mrad2831_5499

Alternate gene names: 170751867

Gene position: 5813318-5812425 (Counterclockwise)

Preceding gene: 170751871

Following gene: 170751864

Centisome position: 95.65

GC content: 73.83

Gene sequence:

>894_bases
ATGGTCCGCGCCGATCTAAACGACTACGTCTACTTCGCCGAGGTCGTCGCGCACGGCGGCTTCGCCGCGGCGGGCCGGGC
GCTGCACCAGCCGAAATCGAAGCTGAGCCGCCGCGTCGCGGCCCTGGAGGCGCGCCTGGGCGCCCGCCTGATCGAGCGGT
CGAGCCGGCGCTTCCGCGTGACCGAAGTCGGCCAGGGCTTCTACGAGCGCTGCCGGGCGATGATGCTGGAGGCGGAGCGG
GCCGAGGCGCTGGTCGCGGAAGCGCAGACCGAGCCGCACGGGCGGATCCGCATGAGCTGCCCGTCGGGCCTCGCCGACAT
CGTCGCCGCGCGCGTCCGCGGCTTCCTCGTCCGCTACCCGAAGGTGAGGCTGCAGCTGGTCGTGACCGACCGGCCCGTCG
ACCTGATCGAGGAGCGGATCGACGTGGCGCTGCGTGTGCGGCGAGACCTGACGAGCGACGCGTCGCTGACCATGCGCACG
CTCGGATCCTCGCGCTGGATCCTGGTCGCCGCGCCGCAGGTGGCGCGCGGCCTCGGTCCCGACATCGCCGCGCTCGGCGC
TGTCCCGACGCTCGGCACCCGCGACGATCCGGGCGAGGCGGAGTGGCGGCTCGAGCACCGTGACGGCACGGTCGTCACCC
TGCGCCACGAGCCGCGCCTGACCTGCGGCGACTTCGCCGCGCTCACCGACGCGGCGGCTGACGGTCTCGGGGTCGCGTTC
CTGCCCGACCACGCCTGCACCGACGCCGTCGCGGCGGGTCGGCTCGTGCCCGTCTATCCGGACTGGCAGGGCCAGCCCGG
GATCGTGCACATCGTCTTCACGACTCGGCGCGGGCTGCCGCCGGCCGTGCGCGTGCTGATCGACCACCTCGCGGCGACAT
TCCCGAAGCTGTGA

Upstream 100 bases:

>100_bases
GTGCTGCGGCCCCGTATGCGCCGCTGGCCGGAGAGATGCCGCCGGAACGATGATGCGGGTAGCCCGCGAATGTGGCACCC
AGCGTTCCACTGGAGGAACG

Downstream 100 bases:

>100_bases
CGCGCGCGTCTCAGTACCCCCGCGCCGCGTCGACGCCGTCCGGCACCTGACCGGTCCGCCGATAGGCCCGCAGGTTGGCC
GCCACCGTGGCGGCCGCCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVRADLNDYVYFAEVVAHGGFAAAGRALHQPKSKLSRRVAALEARLGARLIERSSRRFRVTEVGQGFYERCRAMMLEAER
AEALVAEAQTEPHGRIRMSCPSGLADIVAARVRGFLVRYPKVRLQLVVTDRPVDLIEERIDVALRVRRDLTSDASLTMRT
LGSSRWILVAAPQVARGLGPDIAALGAVPTLGTRDDPGEAEWRLEHRDGTVVTLRHEPRLTCGDFAALTDAAADGLGVAF
LPDHACTDAVAAGRLVPVYPDWQGQPGIVHIVFTTRRGLPPAVRVLIDHLAATFPKL

Sequences:

>Translated_297_residues
MVRADLNDYVYFAEVVAHGGFAAAGRALHQPKSKLSRRVAALEARLGARLIERSSRRFRVTEVGQGFYERCRAMMLEAER
AEALVAEAQTEPHGRIRMSCPSGLADIVAARVRGFLVRYPKVRLQLVVTDRPVDLIEERIDVALRVRRDLTSDASLTMRT
LGSSRWILVAAPQVARGLGPDIAALGAVPTLGTRDDPGEAEWRLEHRDGTVVTLRHEPRLTCGDFAALTDAAADGLGVAF
LPDHACTDAVAAGRLVPVYPDWQGQPGIVHIVFTTRRGLPPAVRVLIDHLAATFPKL
>Mature_297_residues
MVRADLNDYVYFAEVVAHGGFAAAGRALHQPKSKLSRRVAALEARLGARLIERSSRRFRVTEVGQGFYERCRAMMLEAER
AEALVAEAQTEPHGRIRMSCPSGLADIVAARVRGFLVRYPKVRLQLVVTDRPVDLIEERIDVALRVRRDLTSDASLTMRT
LGSSRWILVAAPQVARGLGPDIAALGAVPTLGTRDDPGEAEWRLEHRDGTVVTLRHEPRLTCGDFAALTDAAADGLGVAF
LPDHACTDAVAAGRLVPVYPDWQGQPGIVHIVFTTRRGLPPAVRVLIDHLAATFPKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=29.7202797202797, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=28.0405405405405, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=27.7591973244147, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=27.7591973244147, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=24.1379310344828, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787128, Length=300, Percent_Identity=24, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32446; Mature: 32446

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRADLNDYVYFAEVVAHGGFAAAGRALHQPKSKLSRRVAALEARLGARLIERSSRRFRV
CCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TEVGQGFYERCRAMMLEAERAEALVAEAQTEPHGRIRMSCPSGLADIVAARVRGFLVRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
KVRLQLVVTDRPVDLIEERIDVALRVRRDLTSDASLTMRTLGSSRWILVAAPQVARGLGP
CEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCHHHHCCCC
DIAALGAVPTLGTRDDPGEAEWRLEHRDGTVVTLRHEPRLTCGDFAALTDAAADGLGVAF
CHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEE
LPDHACTDAVAAGRLVPVYPDWQGQPGIVHIVFTTRRGLPPAVRVLIDHLAATFPKL
CCCHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVRADLNDYVYFAEVVAHGGFAAAGRALHQPKSKLSRRVAALEARLGARLIERSSRRFRV
CCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TEVGQGFYERCRAMMLEAERAEALVAEAQTEPHGRIRMSCPSGLADIVAARVRGFLVRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
KVRLQLVVTDRPVDLIEERIDVALRVRRDLTSDASLTMRTLGSSRWILVAAPQVARGLGP
CEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCHHHHCCCC
DIAALGAVPTLGTRDDPGEAEWRLEHRDGTVVTLRHEPRLTCGDFAALTDAAADGLGVAF
CHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEE
LPDHACTDAVAAGRLVPVYPDWQGQPGIVHIVFTTRRGLPPAVRVLIDHLAATFPKL
CCCHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]