Click here to switch to the map view.

The map label for this gene is 170751819

Identifier: 170751819

GI number: 170751819

Start: 5758853

End: 5760319

Strand: Reverse

Name: 170751819

Synonym: Mrad2831_5449

Alternate gene names: NA

Gene position: 5760319-5758853 (Counterclockwise)

Preceding gene: 170751820

Following gene: 170751817

Centisome position: 94.78

GC content: 71.57

Gene sequence:

>1467_bases
ATGACCGAGCCCGCGTCCGAGACCCTGGCCGTCCTGATCGTCGGCGCCGGCTTCTCGGGGCTCGCGATGGCGATCCGCTG
CCGGCAGGCGGGAATCGGGCCGCTGCGGGTGATCGAGAAGGCCGACGGGATCGGCGGCACGTGGCACGACAACACCTATC
CGGGTGCGGCCTGCGATATCCCCTCGCACCTCTACTCGCTGTCCTTCGCCCCGAAGGCCGACTGGAGCCGGATGTACGCG
CCGCAGCCGGAGATCCTGGCCTACCTCCGGGACACCGCCGAGCGGAACGGGTTGATGCCCCTGATCCAGCTCGGGACGAC
CTTCACCGGAGCCACCTGGGACGCGGAGCGCGCCCTGTGGCACGTGGAGACCGACCGGGAGCGGATCACGGCGCGCGCGA
TCGTCGCGGGCATGGGCGGGCTCCACCATCCGGCCTTCCCGGACATCCCGGGCCGCGACGCGTTCGCCGGCCCCGCCTTC
CACACGGCGGCCTGGGATCACTCCGCGGCGCTGGCCGGCAAGCGCGTCGGGGTGATCGGCACCGGTGCGAGCGCGATCCA
GGTGGTGCCGGAACTCGCCGCCGTCGCGTCCCAGCTGACGCTGTTCCAGCGCACCCCGCCCTGGATCATGCCCAAGAACG
ATCACGCCATCGCGGAGCGTGCCCGGGACCGCTACCGGCGCCTGCCGCTCAGCCGGCGGCTCGAGCGGGCGCGGCTGTTC
TGGCTGCACGAGGTGCGGGCGCTGCTCGGCTTCACCAAGGTCTCGAAGCTCACCGGCCAGGCCGAATCCCTCGCGCGGCA
CCATCTCGCCAAGGCTGTCCCCGACAAGGCCCTGCGGGCGAAGCTGACGCCGAACTACCGGCTCGGCTGCAAGCGGGTGC
TGATCTCCGACGACTACTACCCCGCGCTCCAGCGCCCGAACGTCACCCTGGAGACGGACGGCATCGCCCGGATCACCGAG
ACCGGCGTGACCACCGAGACCGGGCGGCATCACGAGCTCGACGTGATCGTCTACGCCACGGGTTTCGACGTGGCCGCGAC
CTTCGCGCGGATGCACCTCGTCGGCCGCGACGGCCGGAGCCTGACCGAGGCCTGGGCCGGCGGCGTGGGCGCCTACCAGG
GCATCACGGTCGCGGGGTTCCCGAACTTCTTCATGCTGCTCGGGCCCAATACCGGGCTGGGCCACAACTCGGTCGTCTCG
ATGATCGAGATCCAGGTGCAGCACGTCCTCGACTGCCTGACAGCGCTCGGGCGCGGGACGAAGACCGTCGAGGTCCGGCC
GGAGGCTCAGGCCCGATTCGTCGACCGGCTCCAGAGCCGCATGGCCGACAGCATCTGGCAGGCCGGGGGCTGCCGCAGCT
GGTACCTCGACGCGACCGGGCGCAACAGCACCCTCTGGCCCGACTCGGTCATGGCCTATCGCCGGAGCGCCCGCCGCGCC
CGGCTGAGGGATTACAGGCTCGGCTGA

Upstream 100 bases:

>100_bases
TCGCCGCCGGCGTGCTGCCCGAGGCGCGAACCTCCCTCGACGAGGCCGCGGCCTTCCTGACGGCGCACGCGCCCCACGCC
CCCTTCGGGAGCCCTCAGCG

Downstream 100 bases:

>100_bases
TCGGGGCGCACGCGTGCGCCGCCTCGGCGCGGTGTCAGAACGCGAAGCCGGCTTCCGCCGCGAAGGCCTCCAGATTGGGC
AGCGACGCGTCGAACAGCGG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTEPASETLAVLIVGAGFSGLAMAIRCRQAGIGPLRVIEKADGIGGTWHDNTYPGAACDIPSHLYSLSFAPKADWSRMYA
PQPEILAYLRDTAERNGLMPLIQLGTTFTGATWDAERALWHVETDRERITARAIVAGMGGLHHPAFPDIPGRDAFAGPAF
HTAAWDHSAALAGKRVGVIGTGASAIQVVPELAAVASQLTLFQRTPPWIMPKNDHAIAERARDRYRRLPLSRRLERARLF
WLHEVRALLGFTKVSKLTGQAESLARHHLAKAVPDKALRAKLTPNYRLGCKRVLISDDYYPALQRPNVTLETDGIARITE
TGVTTETGRHHELDVIVYATGFDVAATFARMHLVGRDGRSLTEAWAGGVGAYQGITVAGFPNFFMLLGPNTGLGHNSVVS
MIEIQVQHVLDCLTALGRGTKTVEVRPEAQARFVDRLQSRMADSIWQAGGCRSWYLDATGRNSTLWPDSVMAYRRSARRA
RLRDYRLG

Sequences:

>Translated_488_residues
MTEPASETLAVLIVGAGFSGLAMAIRCRQAGIGPLRVIEKADGIGGTWHDNTYPGAACDIPSHLYSLSFAPKADWSRMYA
PQPEILAYLRDTAERNGLMPLIQLGTTFTGATWDAERALWHVETDRERITARAIVAGMGGLHHPAFPDIPGRDAFAGPAF
HTAAWDHSAALAGKRVGVIGTGASAIQVVPELAAVASQLTLFQRTPPWIMPKNDHAIAERARDRYRRLPLSRRLERARLF
WLHEVRALLGFTKVSKLTGQAESLARHHLAKAVPDKALRAKLTPNYRLGCKRVLISDDYYPALQRPNVTLETDGIARITE
TGVTTETGRHHELDVIVYATGFDVAATFARMHLVGRDGRSLTEAWAGGVGAYQGITVAGFPNFFMLLGPNTGLGHNSVVS
MIEIQVQHVLDCLTALGRGTKTVEVRPEAQARFVDRLQSRMADSIWQAGGCRSWYLDATGRNSTLWPDSVMAYRRSARRA
RLRDYRLG
>Mature_487_residues
TEPASETLAVLIVGAGFSGLAMAIRCRQAGIGPLRVIEKADGIGGTWHDNTYPGAACDIPSHLYSLSFAPKADWSRMYAP
QPEILAYLRDTAERNGLMPLIQLGTTFTGATWDAERALWHVETDRERITARAIVAGMGGLHHPAFPDIPGRDAFAGPAFH
TAAWDHSAALAGKRVGVIGTGASAIQVVPELAAVASQLTLFQRTPPWIMPKNDHAIAERARDRYRRLPLSRRLERARLFW
LHEVRALLGFTKVSKLTGQAESLARHHLAKAVPDKALRAKLTPNYRLGCKRVLISDDYYPALQRPNVTLETDGIARITET
GVTTETGRHHELDVIVYATGFDVAATFARMHLVGRDGRSLTEAWAGGVGAYQGITVAGFPNFFMLLGPNTGLGHNSVVSM
IEIQVQHVLDCLTALGRGTKTVEVRPEAQARFVDRLQSRMADSIWQAGGCRSWYLDATGRNSTLWPDSVMAYRRSARRAR
LRDYRLG

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=377, Percent_Identity=24.4031830238727, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4503757, Length=374, Percent_Identity=23.5294117647059, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI50541965, Length=360, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI50541961, Length=360, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4503759, Length=364, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI221316672, Length=360, Percent_Identity=24.1666666666667, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI221316674, Length=360, Percent_Identity=24.1666666666667, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI221316678, Length=218, Percent_Identity=26.1467889908257, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145785, Length=358, Percent_Identity=21.5083798882682, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 53546; Mature: 53415

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPASETLAVLIVGAGFSGLAMAIRCRQAGIGPLRVIEKADGIGGTWHDNTYPGAACDI
CCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
PSHLYSLSFAPKADWSRMYAPQPEILAYLRDTAERNGLMPLIQLGTTFTGATWDAERALW
CHHHHEECCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHCEE
HVETDRERITARAIVAGMGGLHHPAFPDIPGRDAFAGPAFHTAAWDHSAALAGKRVGVIG
EEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCEEEEE
TGASAIQVVPELAAVASQLTLFQRTPPWIMPKNDHAIAERARDRYRRLPLSRRLERARLF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
WLHEVRALLGFTKVSKLTGQAESLARHHLAKAVPDKALRAKLTPNYRLGCKRVLISDDYY
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHEECCCCCCCCCEEEEECCCCC
PALQRPNVTLETDGIARITETGVTTETGRHHELDVIVYATGFDVAATFARMHLVGRDGRS
CCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCH
LTEAWAGGVGAYQGITVAGFPNFFMLLGPNTGLGHNSVVSMIEIQVQHVLDCLTALGRGT
HHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KTVEVRPEAQARFVDRLQSRMADSIWQAGGCRSWYLDATGRNSTLWPDSVMAYRRSARRA
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
RLRDYRLG
HHHHCCCC
>Mature Secondary Structure 
TEPASETLAVLIVGAGFSGLAMAIRCRQAGIGPLRVIEKADGIGGTWHDNTYPGAACDI
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
PSHLYSLSFAPKADWSRMYAPQPEILAYLRDTAERNGLMPLIQLGTTFTGATWDAERALW
CHHHHEECCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHCEE
HVETDRERITARAIVAGMGGLHHPAFPDIPGRDAFAGPAFHTAAWDHSAALAGKRVGVIG
EEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCEEEEE
TGASAIQVVPELAAVASQLTLFQRTPPWIMPKNDHAIAERARDRYRRLPLSRRLERARLF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
WLHEVRALLGFTKVSKLTGQAESLARHHLAKAVPDKALRAKLTPNYRLGCKRVLISDDYY
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHEECCCCCCCCCEEEEECCCCC
PALQRPNVTLETDGIARITETGVTTETGRHHELDVIVYATGFDVAATFARMHLVGRDGRS
CCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCH
LTEAWAGGVGAYQGITVAGFPNFFMLLGPNTGLGHNSVVSMIEIQVQHVLDCLTALGRGT
HHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KTVEVRPEAQARFVDRLQSRMADSIWQAGGCRSWYLDATGRNSTLWPDSVMAYRRSARRA
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
RLRDYRLG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]