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The map label for this gene is eriC [C]

Identifier: 170751719

GI number: 170751719

Start: 5656163

End: 5657980

Strand: Direct

Name: eriC [C]

Synonym: Mrad2831_5349

Alternate gene names: 170751719

Gene position: 5656163-5657980 (Clockwise)

Preceding gene: 170751717

Following gene: 170751720

Centisome position: 93.06

GC content: 74.53

Gene sequence:

>1818_bases
ATGATCGGCGGGACTGGGAGCGGCAGCGGGGAGGGCAGCCCGTCGCGCCGGGCGCTGGGGGATTTCAGCGCGGACCGGCG
GGTCCTGACGCTGGCCGGCATGGCGATCGTCACCGGGACCGCCGCCAGCGGCACCGCCTGGATCCTGCTCACGCTGATCG
GCCTCGTCACCAATCTCGTGTGGTACGGCCGGCTCGACACCGCCCTGACCTCCCTGGCCGGCGCGGCGCCGGGGCCCTCG
ATGGTGGCGATCCCGGTGATCGGGGCGCTGATCGTCGGCGCCATGGCGCGCTACGGCTCGGAGAAGATCCGCGGCCACGG
GATCCCGGAGGCGATGGAGGCGATCCTGGTCGGCGGCAGCCGGATGTCGCCCAGGGTCGCCGTGCTCAAGCCGCTCTCCT
CGGCGGTCGCGATCGGCACCGGCGGACCGTTCGGCGCCGAGGGACCGATCATCGTGACGGGCGGCGCGGTCGGCTCGCTC
TTCGCCCAGTTCTTCCATCTCAGCGCCGCCGAGCGGAAGACGCTGCTGGTGGCGGGCGCGGCGGCGGGCATGACCGCCAT
CTTCGGGACGCCCGTGGCGGCCGTGCTGCTCGCCGTCGAGGTTCTGCTGTTCGAGTGGCGGCCGCGGAGCCTCGTGCCGG
TGACCGTCGGGGCTGTCACCGCGGCCTGCTGGCGGCCGGCCCTGTTCGGCGCCGGCCCGCTCTTTCCCTTCGCCGACAAT
CCGGTCCTGCCCTGGTGGGGGCTGCCCGCCTGCGCGCTGCTCGGCGTCGCCTGCGGCCTCATCTCGGGGGGGCTGACCCG
GGCCCTCTACGCGCTGGAGGACGGCTTCGGGCGGCTTCCCCTGCACTGGATGTGGTGGCCCGCCATCGGCGCCGTCGTGG
TCGGGCTGGGCGGCCTCGTGGAGCCCCGGGCGCTCGGCGTCGGCTACGACGTCATCCACGACCTGCTCTCCGGCCACATG
CTGGCGAGCGCCGTCGTGCTGATCCTCGTGGTCAAGGCGGCGATCTGGCTCGCCGCCCTGTCGTCGGGCACGTCCGGAGG
CGTGCTCGCGCCGCTGCTGATCCTCGGCGGCGCCGTCGGCTGGCTGATCGGCGTCCTCCTGCCCGGCGCCCACGGTTTCT
GGGCGCTCATCGGCATGGCGGCGATGCTCGGCGGCACCCTGCCGGCGCCGCTGACCGGCGTCGTCTTCGCCGTCGAGGTG
ACCGGCGACGTCGCCGCCCTGGCGCCGCTGCTCGCCGCCACCGTGGCGGCCTACGCGGTGACCGTGCTCCTCCTCAAGCG
CTCGATCCTGACCGAGAAGATCGCCCGGCGCGGGCAGCACGTGACCCGGGAATACGGGATCGATCCCTACGATCTCGCCC
GGGTCGAGGCGGTGATGACCCGCACGGTCGAGACCCTGGACGCGGACCTGCCCCTGGCCGAGGCCCTCGCGGCCATCGAG
ACCGGCGCCCACCACGCCTACCCGGTGGTCGACGGCGCGGGCCGGCCCGTCGGCCTCGTCTCGCGCAACGACGCCCTCCG
CTGGACCCTGGAGGAGCGCGACGGCGCGGCCGAGGAGGGCACCCTCGGCGAGCGCGTCTCGGACGCCGATCTCGCCGTCG
TCCATCCGGGCGACGTGGTCTCGCACGCCCTCGACGTCATGCTGTCGGCCGGGCAGGGGCGCCTGCCGGTCACCGATCCG
CGCACCGGCGGCCTCGTCGGGCTCCTCACCCGCAAGGACCTGCTCCAGGTGCGCGCCACGGTGGTGCGGGCCGAAGCCGA
GCGCCGCGCGTTCTACCGGAAGGGGCGGGGTGAAAGGCGCGCACGGATGGAAGCATGA

Upstream 100 bases:

>100_bases
TGCCCCGTATCGACGGGCTGGTCCCGGCTCGCAATGGCCGCGCCGTTGCAAGATATATCGGATTACGACATAAAAGCCGC
CGCGAAGGAAGGAGGCCCCG

Downstream 100 bases:

>100_bases
CCCTGGACCCGCACCGTCCCGGCCGGACCACCCGCCTCGATCGGCTCGCGCCGGGCAGCTTCTACCTGATCGCCGGCCGG
GACGGGCCGGATCTCGCCCT

Product: chloride channel core

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MIGGTGSGSGEGSPSRRALGDFSADRRVLTLAGMAIVTGTAASGTAWILLTLIGLVTNLVWYGRLDTALTSLAGAAPGPS
MVAIPVIGALIVGAMARYGSEKIRGHGIPEAMEAILVGGSRMSPRVAVLKPLSSAVAIGTGGPFGAEGPIIVTGGAVGSL
FAQFFHLSAAERKTLLVAGAAAGMTAIFGTPVAAVLLAVEVLLFEWRPRSLVPVTVGAVTAACWRPALFGAGPLFPFADN
PVLPWWGLPACALLGVACGLISGGLTRALYALEDGFGRLPLHWMWWPAIGAVVVGLGGLVEPRALGVGYDVIHDLLSGHM
LASAVVLILVVKAAIWLAALSSGTSGGVLAPLLILGGAVGWLIGVLLPGAHGFWALIGMAAMLGGTLPAPLTGVVFAVEV
TGDVAALAPLLAATVAAYAVTVLLLKRSILTEKIARRGQHVTREYGIDPYDLARVEAVMTRTVETLDADLPLAEALAAIE
TGAHHAYPVVDGAGRPVGLVSRNDALRWTLEERDGAAEEGTLGERVSDADLAVVHPGDVVSHALDVMLSAGQGRLPVTDP
RTGGLVGLLTRKDLLQVRATVVRAEAERRAFYRKGRGERRARMEA

Sequences:

>Translated_605_residues
MIGGTGSGSGEGSPSRRALGDFSADRRVLTLAGMAIVTGTAASGTAWILLTLIGLVTNLVWYGRLDTALTSLAGAAPGPS
MVAIPVIGALIVGAMARYGSEKIRGHGIPEAMEAILVGGSRMSPRVAVLKPLSSAVAIGTGGPFGAEGPIIVTGGAVGSL
FAQFFHLSAAERKTLLVAGAAAGMTAIFGTPVAAVLLAVEVLLFEWRPRSLVPVTVGAVTAACWRPALFGAGPLFPFADN
PVLPWWGLPACALLGVACGLISGGLTRALYALEDGFGRLPLHWMWWPAIGAVVVGLGGLVEPRALGVGYDVIHDLLSGHM
LASAVVLILVVKAAIWLAALSSGTSGGVLAPLLILGGAVGWLIGVLLPGAHGFWALIGMAAMLGGTLPAPLTGVVFAVEV
TGDVAALAPLLAATVAAYAVTVLLLKRSILTEKIARRGQHVTREYGIDPYDLARVEAVMTRTVETLDADLPLAEALAAIE
TGAHHAYPVVDGAGRPVGLVSRNDALRWTLEERDGAAEEGTLGERVSDADLAVVHPGDVVSHALDVMLSAGQGRLPVTDP
RTGGLVGLLTRKDLLQVRATVVRAEAERRAFYRKGRGERRARMEA
>Mature_605_residues
MIGGTGSGSGEGSPSRRALGDFSADRRVLTLAGMAIVTGTAASGTAWILLTLIGLVTNLVWYGRLDTALTSLAGAAPGPS
MVAIPVIGALIVGAMARYGSEKIRGHGIPEAMEAILVGGSRMSPRVAVLKPLSSAVAIGTGGPFGAEGPIIVTGGAVGSL
FAQFFHLSAAERKTLLVAGAAAGMTAIFGTPVAAVLLAVEVLLFEWRPRSLVPVTVGAVTAACWRPALFGAGPLFPFADN
PVLPWWGLPACALLGVACGLISGGLTRALYALEDGFGRLPLHWMWWPAIGAVVVGLGGLVEPRALGVGYDVIHDLLSGHM
LASAVVLILVVKAAIWLAALSSGTSGGVLAPLLILGGAVGWLIGVLLPGAHGFWALIGMAAMLGGTLPAPLTGVVFAVEV
TGDVAALAPLLAATVAAYAVTVLLLKRSILTEKIARRGQHVTREYGIDPYDLARVEAVMTRTVETLDADLPLAEALAAIE
TGAHHAYPVVDGAGRPVGLVSRNDALRWTLEERDGAAEEGTLGERVSDADLAVVHPGDVVSHALDVMLSAGQGRLPVTDP
RTGGLVGLLTRKDLLQVRATVVRAEAERRAFYRKGRGERRARMEA

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=319, Percent_Identity=29.7805642633229, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081943, Length=437, Percent_Identity=28.1464530892449, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62204; Mature: 62204

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGGTGSGSGEGSPSRRALGDFSADRRVLTLAGMAIVTGTAASGTAWILLTLIGLVTNLV
CCCCCCCCCCCCCCCHHHHCCCCCCCEEHEECCHHHEECCCCCCHHHHHHHHHHHHHHHH
WYGRLDTALTSLAGAAPGPSMVAIPVIGALIVGAMARYGSEKIRGHGIPEAMEAILVGGS
HHCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCC
RMSPRVAVLKPLSSAVAIGTGGPFGAEGPIIVTGGAVGSLFAQFFHLSAAERKTLLVAGA
CCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEEC
AAGMTAIFGTPVAAVLLAVEVLLFEWRPRSLVPVTVGAVTAACWRPALFGAGPLFPFADN
HHCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCC
PVLPWWGLPACALLGVACGLISGGLTRALYALEDGFGRLPLHWMWWPAIGAVVVGLGGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCC
EPRALGVGYDVIHDLLSGHMLASAVVLILVVKAAIWLAALSSGTSGGVLAPLLILGGAVG
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
WLIGVLLPGAHGFWALIGMAAMLGGTLPAPLTGVVFAVEVTGDVAALAPLLAATVAAYAV
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
TVLLLKRSILTEKIARRGQHVTREYGIDPYDLARVEAVMTRTVETLDADLPLAEALAAIE
HHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TGAHHAYPVVDGAGRPVGLVSRNDALRWTLEERDGAAEEGTLGERVSDADLAVVHPGDVV
CCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCHHHH
SHALDVMLSAGQGRLPVTDPRTGGLVGLLTRKDLLQVRATVVRAEAERRAFYRKGRGERR
HHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ARMEA
HCCCC
>Mature Secondary Structure
MIGGTGSGSGEGSPSRRALGDFSADRRVLTLAGMAIVTGTAASGTAWILLTLIGLVTNLV
CCCCCCCCCCCCCCCHHHHCCCCCCCEEHEECCHHHEECCCCCCHHHHHHHHHHHHHHHH
WYGRLDTALTSLAGAAPGPSMVAIPVIGALIVGAMARYGSEKIRGHGIPEAMEAILVGGS
HHCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCC
RMSPRVAVLKPLSSAVAIGTGGPFGAEGPIIVTGGAVGSLFAQFFHLSAAERKTLLVAGA
CCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEEC
AAGMTAIFGTPVAAVLLAVEVLLFEWRPRSLVPVTVGAVTAACWRPALFGAGPLFPFADN
HHCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCC
PVLPWWGLPACALLGVACGLISGGLTRALYALEDGFGRLPLHWMWWPAIGAVVVGLGGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCC
EPRALGVGYDVIHDLLSGHMLASAVVLILVVKAAIWLAALSSGTSGGVLAPLLILGGAVG
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
WLIGVLLPGAHGFWALIGMAAMLGGTLPAPLTGVVFAVEVTGDVAALAPLLAATVAAYAV
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
TVLLLKRSILTEKIARRGQHVTREYGIDPYDLARVEAVMTRTVETLDADLPLAEALAAIE
HHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TGAHHAYPVVDGAGRPVGLVSRNDALRWTLEERDGAAEEGTLGERVSDADLAVVHPGDVV
CCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCHHHH
SHALDVMLSAGQGRLPVTDPRTGGLVGLLTRKDLLQVRATVVRAEAERRAFYRKGRGERR
HHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ARMEA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]