Click here to switch to the map view.

The map label for this gene is ftsY [H]

Identifier: 170751708

GI number: 170751708

Start: 5648158

End: 5649558

Strand: Direct

Name: ftsY [H]

Synonym: Mrad2831_5338

Alternate gene names: 170751708

Gene position: 5648158-5649558 (Clockwise)

Preceding gene: 170751706

Following gene: 170751709

Centisome position: 92.93

GC content: 74.88

Gene sequence:

>1401_bases
ATGGCGAGCGAGGAGAAGCCCGGCTGGTTCGGACGCCTGTTCGGGCGCAAAGGCCAGCCCGCGCCCGAGGACAGAGGCGA
GGACCGGCCCGAGGACAAGCCCGAGGCCGACCTGCCGGCCGGGGCGGCCTCGCCCTCCGAGGGGGAGCCGGACTTCGCCA
CCGCCGCCGAGGATGTCGCGCACGTCCCGCTGCCGCCGGAGGAGTCCGGGGAGCCGGTCCCGGACGCGGTCGAGGGCGCG
GACCTGCTGCCCGTGGAGGGCGACGCGGAGCGCCCGCCGGCCGGCACCGCCGGCGACGACCCCGCGCACGGCGCCGACCC
GGTCGACACCGGCGACGTGAACCGGGCGCCGGTGGTCGAGCCGGCCGCCGCGATGCAGCCCGGGATTCAACCCGACGTCC
AGCCCGACATCCAGCCTGTCGACAGCGCCGCGGCCCTCGCCCACGACGCCGGCGCCGGGCCGGAGCGCGAGCCGGAGGCC
AAGGGCTGGTGGAGCCGCCTCACCTCGGGGATGAAGCGGACCTCGTCGGCCCTCTCCGACCGCGTCACCGGCCTGTTCAC
CAAGCGCAAGCTCGACGCCACGACCCTGGAGGACCTGGAGGACGCGCTGATCCAGGCCGATTTCGGCCTGGAGACCGCGA
TGCGGGTCTCGGAGGCCGTCGGCAAGGGCCGCTACGAGAAGGGCATCTCGCCCGACGAGGTCCGGGCGATCCTGGCCGCG
GAGGTGGAGCGGGCGCTGGAGCCGGTGGCGGTGCCGCTGACGATCGACGCCGCCCGGAAGCCCTTCGTGATCCTGACGGT
CGGCGTGAACGGCGCCGGCAAGACCACGACGCTCGGCAAGCTCGCCTCGAAGCTGCGGGCGGAGGGGCGCACCGTGATGC
TCGCGGCCGGCGACACCTTCCGCGCGGCGGCGATCGACCAGCTCAAGGTCTGGGGGGCGCGCACCGGCACGCCGGTGGTG
AGCGGCGCGCAGGGCGCGGACGCGGCGGGCCTCGCCTTCGACGCCCTGAAGCAGGCGGGCGCCGCCGGCACCGACGTGCT
GCTGATCGACACCGCCGGCCGGCTCCAGAACAAGGCCGGCCTGATGGCGGAGCTGGAGAAGATCGTCCGCGTGCTGCGCA
AGCAGGATCCGGATGCGCCGCACGCGACGCTCCTCGTCCTCGACGCCACGGTCGGCCAGAACGCGCTCAGCCAGGTGGAG
CTGTTCTCGCAGGCGGCGCCGGTCTCGGGGCTGGTGATGACCAAGCTCGACGGCACTGCCCGGGGCGGCATCCTGGTGGC
GCTGGCGGCGAAGTTCGGCCTGCCGGTGCACTTCATCGGCGTCGGCGAGGGCGTGGAGGACCTGGAGCCCTTCGCGGCCC
GCGACTTCGCCCGGGCGATCGCCGGACTGGAGAAGGACTAG

Upstream 100 bases:

>100_bases
CGCGGTAGAGGAGGCGCGCGCCTATGTCGAAGGCGTTGGACATCCGGATCGGCTAGAGGGTCGGTGTCGGCGGGGCAAGG
TGGGGCGAGGACGCGATTTC

Downstream 100 bases:

>100_bases
CACGCGGGCGGCCGCCGCTCCTGGGTGCGCGATGTCATGGACATCGCGCGCTCCGCGTTCCACACACCCCGGCGAATCCC
GTCCGACGCCCCCGGCCGAC

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MASEEKPGWFGRLFGRKGQPAPEDRGEDRPEDKPEADLPAGAASPSEGEPDFATAAEDVAHVPLPPEESGEPVPDAVEGA
DLLPVEGDAERPPAGTAGDDPAHGADPVDTGDVNRAPVVEPAAAMQPGIQPDVQPDIQPVDSAAALAHDAGAGPEREPEA
KGWWSRLTSGMKRTSSALSDRVTGLFTKRKLDATTLEDLEDALIQADFGLETAMRVSEAVGKGRYEKGISPDEVRAILAA
EVERALEPVAVPLTIDAARKPFVILTVGVNGAGKTTTLGKLASKLRAEGRTVMLAAGDTFRAAAIDQLKVWGARTGTPVV
SGAQGADAAGLAFDALKQAGAAGTDVLLIDTAGRLQNKAGLMAELEKIVRVLRKQDPDAPHATLLVLDATVGQNALSQVE
LFSQAAPVSGLVMTKLDGTARGGILVALAAKFGLPVHFIGVGEGVEDLEPFAARDFARAIAGLEKD

Sequences:

>Translated_466_residues
MASEEKPGWFGRLFGRKGQPAPEDRGEDRPEDKPEADLPAGAASPSEGEPDFATAAEDVAHVPLPPEESGEPVPDAVEGA
DLLPVEGDAERPPAGTAGDDPAHGADPVDTGDVNRAPVVEPAAAMQPGIQPDVQPDIQPVDSAAALAHDAGAGPEREPEA
KGWWSRLTSGMKRTSSALSDRVTGLFTKRKLDATTLEDLEDALIQADFGLETAMRVSEAVGKGRYEKGISPDEVRAILAA
EVERALEPVAVPLTIDAARKPFVILTVGVNGAGKTTTLGKLASKLRAEGRTVMLAAGDTFRAAAIDQLKVWGARTGTPVV
SGAQGADAAGLAFDALKQAGAAGTDVLLIDTAGRLQNKAGLMAELEKIVRVLRKQDPDAPHATLLVLDATVGQNALSQVE
LFSQAAPVSGLVMTKLDGTARGGILVALAAKFGLPVHFIGVGEGVEDLEPFAARDFARAIAGLEKD
>Mature_465_residues
ASEEKPGWFGRLFGRKGQPAPEDRGEDRPEDKPEADLPAGAASPSEGEPDFATAAEDVAHVPLPPEESGEPVPDAVEGAD
LLPVEGDAERPPAGTAGDDPAHGADPVDTGDVNRAPVVEPAAAMQPGIQPDVQPDIQPVDSAAALAHDAGAGPEREPEAK
GWWSRLTSGMKRTSSALSDRVTGLFTKRKLDATTLEDLEDALIQADFGLETAMRVSEAVGKGRYEKGISPDEVRAILAAE
VERALEPVAVPLTIDAARKPFVILTVGVNGAGKTTTLGKLASKLRAEGRTVMLAAGDTFRAAAIDQLKVWGARTGTPVVS
GAQGADAAGLAFDALKQAGAAGTDVLLIDTAGRLQNKAGLMAELEKIVRVLRKQDPDAPHATLLVLDATVGQNALSQVEL
FSQAAPVSGLVMTKLDGTARGGILVALAAKFGLPVHFIGVGEGVEDLEPFAARDFARAIAGLEKD

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI295424842, Length=299, Percent_Identity=29.7658862876254, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI23308697, Length=299, Percent_Identity=29.7658862876254, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI226371618, Length=204, Percent_Identity=31.8627450980392, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4507215, Length=296, Percent_Identity=27.3648648648649, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI89061728, Length=119, Percent_Identity=30.2521008403361, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1789874, Length=314, Percent_Identity=46.4968152866242, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1788963, Length=307, Percent_Identity=34.5276872964169, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=273, Percent_Identity=28.9377289377289, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193206261, Length=303, Percent_Identity=32.013201320132, Blast_Score=114, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=312, Percent_Identity=29.4871794871795, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320498, Length=223, Percent_Identity=29.5964125560538, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24641198, Length=294, Percent_Identity=30.6122448979592, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17647949, Length=280, Percent_Identity=29.2857142857143, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 48246; Mature: 48114

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEEKPGWFGRLFGRKGQPAPEDRGEDRPEDKPEADLPAGAASPSEGEPDFATAAEDVA
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
HVPLPPEESGEPVPDAVEGADLLPVEGDAERPPAGTAGDDPAHGADPVDTGDVNRAPVVE
CCCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAAAMQPGIQPDVQPDIQPVDSAAALAHDAGAGPEREPEAKGWWSRLTSGMKRTSSALSD
CHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RVTGLFTKRKLDATTLEDLEDALIQADFGLETAMRVSEAVGKGRYEKGISPDEVRAILAA
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHH
EVERALEPVAVPLTIDAARKPFVILTVGVNGAGKTTTLGKLASKLRAEGRTVMLAAGDTF
HHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCH
RAAAIDQLKVWGARTGTPVVSGAQGADAAGLAFDALKQAGAAGTDVLLIDTAGRLQNKAG
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHH
LMAELEKIVRVLRKQDPDAPHATLLVLDATVGQNALSQVELFSQAAPVSGLVMTKLDGTA
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
RGGILVALAAKFGLPVHFIGVGEGVEDLEPFAARDFARAIAGLEKD
CCCEEEEEEHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASEEKPGWFGRLFGRKGQPAPEDRGEDRPEDKPEADLPAGAASPSEGEPDFATAAEDVA
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
HVPLPPEESGEPVPDAVEGADLLPVEGDAERPPAGTAGDDPAHGADPVDTGDVNRAPVVE
CCCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAAAMQPGIQPDVQPDIQPVDSAAALAHDAGAGPEREPEAKGWWSRLTSGMKRTSSALSD
CHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RVTGLFTKRKLDATTLEDLEDALIQADFGLETAMRVSEAVGKGRYEKGISPDEVRAILAA
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHH
EVERALEPVAVPLTIDAARKPFVILTVGVNGAGKTTTLGKLASKLRAEGRTVMLAAGDTF
HHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCH
RAAAIDQLKVWGARTGTPVVSGAQGADAAGLAFDALKQAGAAGTDVLLIDTAGRLQNKAG
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHH
LMAELEKIVRVLRKQDPDAPHATLLVLDATVGQNALSQVELFSQAAPVSGLVMTKLDGTA
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
RGGILVALAAKFGLPVHFIGVGEGVEDLEPFAARDFARAIAGLEKD
CCCEEEEEEHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]