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The map label for this gene is yleA [C]

Identifier: 170751706

GI number: 170751706

Start: 5646189

End: 5647415

Strand: Direct

Name: yleA [C]

Synonym: Mrad2831_5336

Alternate gene names: 170751706

Gene position: 5646189-5647415 (Clockwise)

Preceding gene: 170751705

Following gene: 170751708

Centisome position: 92.9

GC content: 77.1

Gene sequence:

>1227_bases
ATGGCGGTCGAGACCCTCACCTTCGGCTGCCGCCTCAACACCGTCGAGTCCGAGGCCCTGCGGGTCCACGCGGCGGCGGA
CGGGCGCGACCGGGTGGTGGTGAACACCTGCGCGGTGACCGCCGAGGCCGGGCGGCAGGCCCGCAAGGCGATCCGGCGCC
TCGCCCGGGAGCGGCCCGGCGCCGAGATCGTCGTCACCGGCTGCGGCGCCGAGGTCGAGACGGAGGCCTACGCGGCCATG
CCGGAGGTCGCGCGCCTCGTCGGCAACGCCGAGAAGCTGCGGCCGGAGGGCTGGTCGGCGGCCGCGACCGGCCCGGGCGC
CGTCATGGCGGCGCGGGCGGCCGAGCCGACGCGGGTCGAGGCGGTCGCCGGGCACACCCGCGCCTTCGTGCCCGTGCAGA
ACGGCTGCGACCACCGCTGCACCTTCTGCGTGATCCCGTTCGGGCGGGGCGTCTCCCGCTCGGTGCCGGAGGCGGACGTG
ATCGCGCAGGTCGAGACGATCGTGGCGCGGGGCGGGCGCGAGGTGGTGCTGACCGGCGTCGACCTCACCGCCTACGGTCG
CGACCTCCCCGGCACGGCCCCGTCCCTCGGCGGCCTCGCGCGCGCGATCCTCCGGGCGGTGCCCGACCTCGCGCGCCTGC
GCCTGTCCTCCATCGATTCCGTCGAGGCCGACGACGCGCTGCTCGCGGCGATCGCCGAGGAGGAGCGGCTCATGCCGCAC
CTGCACCTGTCGCTGCAGGCCGGCGACGACCTGATCCTCAAGCGCATGAGGCGCCGGCACCTGCGCGCCGACGCGATCCG
CTTCTGCGAGACCGTGCGGCGGCTGCGGCCCGACACGGTGTTCGGCGCCGACCTGATCGCCGGCTTCCCGACCGAGACCG
AGGCGCAGTTCGACCGCTCCCTCGACCTCGTGGCGGCGTGCGGCCTGACGCACCTGCACGTCTTCCCGTACTCGCCGCGC
CCCGGGACACCGGCCGCGCGCATGCCGCCGGTTGCCCCCGAGGCGATCCGCGCGCGGGCGGCGCGGCTGCGGGCGGCCGG
CGCCGACGCCCTGCGCCGGCATCTCGACGCCCAGGTCGGCCGCCGCCTCACCGTGCTGGCGGAGCGCGGCGGCGTCGGGC
GAAGCGCGGATTTCACCGCGGTTCGGCTTCCGGGCGTCCCCGAAGCGGGGACGTTCCACGACGTCGCCGTCGCCGGGCAC
GACGGCGCGCGGCTCATCGGCGCCTAG

Upstream 100 bases:

>100_bases
TCGTCGAGTGGCGGGCCGACGACCACGTCCTGATGACCGGCCCGGTCGCGCTCGTCGCCGAGGGGACTCTGGCGCCGGAG
CTGTTCGACAGCGCGGCCTG

Downstream 100 bases:

>100_bases
CGCCCGCGGCTCACGCCGGCATCGCCGCCACGGCCTCGGCGATGTGCGGGGGCGGCGGCGCCGTGACGGCGATGGCGTCG
CGCTTCGGGTAGAGCGGGAT

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAVETLTFGCRLNTVESEALRVHAAADGRDRVVVNTCAVTAEAGRQARKAIRRLARERPGAEIVVTGCGAEVETEAYAAM
PEVARLVGNAEKLRPEGWSAAATGPGAVMAARAAEPTRVEAVAGHTRAFVPVQNGCDHRCTFCVIPFGRGVSRSVPEADV
IAQVETIVARGGREVVLTGVDLTAYGRDLPGTAPSLGGLARAILRAVPDLARLRLSSIDSVEADDALLAAIAEEERLMPH
LHLSLQAGDDLILKRMRRRHLRADAIRFCETVRRLRPDTVFGADLIAGFPTETEAQFDRSLDLVAACGLTHLHVFPYSPR
PGTPAARMPPVAPEAIRARAARLRAAGADALRRHLDAQVGRRLTVLAERGGVGRSADFTAVRLPGVPEAGTFHDVAVAGH
DGARLIGA

Sequences:

>Translated_408_residues
MAVETLTFGCRLNTVESEALRVHAAADGRDRVVVNTCAVTAEAGRQARKAIRRLARERPGAEIVVTGCGAEVETEAYAAM
PEVARLVGNAEKLRPEGWSAAATGPGAVMAARAAEPTRVEAVAGHTRAFVPVQNGCDHRCTFCVIPFGRGVSRSVPEADV
IAQVETIVARGGREVVLTGVDLTAYGRDLPGTAPSLGGLARAILRAVPDLARLRLSSIDSVEADDALLAAIAEEERLMPH
LHLSLQAGDDLILKRMRRRHLRADAIRFCETVRRLRPDTVFGADLIAGFPTETEAQFDRSLDLVAACGLTHLHVFPYSPR
PGTPAARMPPVAPEAIRARAARLRAAGADALRRHLDAQVGRRLTVLAERGGVGRSADFTAVRLPGVPEAGTFHDVAVAGH
DGARLIGA
>Mature_407_residues
AVETLTFGCRLNTVESEALRVHAAADGRDRVVVNTCAVTAEAGRQARKAIRRLARERPGAEIVVTGCGAEVETEAYAAMP
EVARLVGNAEKLRPEGWSAAATGPGAVMAARAAEPTRVEAVAGHTRAFVPVQNGCDHRCTFCVIPFGRGVSRSVPEADVI
AQVETIVARGGREVVLTGVDLTAYGRDLPGTAPSLGGLARAILRAVPDLARLRLSSIDSVEADDALLAAIAEEERLMPHL
HLSLQAGDDLILKRMRRRHLRADAIRFCETVRRLRPDTVFGADLIAGFPTETEAQFDRSLDLVAACGLTHLHVFPYSPRP
GTPAARMPPVAPEAIRARAARLRAAGADALRRHLDAQVGRRLTVLAERGGVGRSADFTAVRLPGVPEAGTFHDVAVAGHD
GARLIGA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=380, Percent_Identity=25.5263157894737, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI28872784, Length=381, Percent_Identity=25.7217847769029, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI28872782, Length=381, Percent_Identity=25.7217847769029, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1786882, Length=424, Percent_Identity=27.3584905660377, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787057, Length=391, Percent_Identity=26.8542199488491, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17553146, Length=441, Percent_Identity=28.1179138321995, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71996771, Length=262, Percent_Identity=28.6259541984733, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21356207, Length=403, Percent_Identity=25.5583126550869, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19922432, Length=406, Percent_Identity=26.3546798029557, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 43300; Mature: 43169

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVETLTFGCRLNTVESEALRVHAAADGRDRVVVNTCAVTAEAGRQARKAIRRLARERPG
CCCCEEEECEEECCCCCCCEEEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
AEIVVTGCGAEVETEAYAAMPEVARLVGNAEKLRPEGWSAAATGPGAVMAARAAEPTRVE
CEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEEECCCCCCEEH
AVAGHTRAFVPVQNGCDHRCTFCVIPFGRGVSRSVPEADVIAQVETIVARGGREVVLTGV
EECCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEC
DLTAYGRDLPGTAPSLGGLARAILRAVPDLARLRLSSIDSVEADDALLAAIAEEERLMPH
CCEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCE
LHLSLQAGDDLILKRMRRRHLRADAIRFCETVRRLRPDTVFGADLIAGFPTETEAQFDRS
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCCCCCHHHHHHC
LDLVAACGLTHLHVFPYSPRPGTPAARMPPVAPEAIRARAARLRAAGADALRRHLDAQVG
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHC
RRLTVLAERGGVGRSADFTAVRLPGVPEAGTFHDVAVAGHDGARLIGA
CEEEEEEECCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCEECCC
>Mature Secondary Structure 
AVETLTFGCRLNTVESEALRVHAAADGRDRVVVNTCAVTAEAGRQARKAIRRLARERPG
CCCEEEECEEECCCCCCCEEEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
AEIVVTGCGAEVETEAYAAMPEVARLVGNAEKLRPEGWSAAATGPGAVMAARAAEPTRVE
CEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEEECCCCCCEEH
AVAGHTRAFVPVQNGCDHRCTFCVIPFGRGVSRSVPEADVIAQVETIVARGGREVVLTGV
EECCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEC
DLTAYGRDLPGTAPSLGGLARAILRAVPDLARLRLSSIDSVEADDALLAAIAEEERLMPH
CCEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCE
LHLSLQAGDDLILKRMRRRHLRADAIRFCETVRRLRPDTVFGADLIAGFPTETEAQFDRS
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCCCCCHHHHHHC
LDLVAACGLTHLHVFPYSPRPGTPAARMPPVAPEAIRARAARLRAAGADALRRHLDAQVG
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHC
RRLTVLAERGGVGRSADFTAVRLPGVPEAGTFHDVAVAGHDGARLIGA
CEEEEEEECCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]