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The map label for this gene is ilvH [H]

Identifier: 170751694

GI number: 170751694

Start: 5634402

End: 5634944

Strand: Direct

Name: ilvH [H]

Synonym: Mrad2831_5324

Alternate gene names: 170751694

Gene position: 5634402-5634944 (Clockwise)

Preceding gene: 170751693

Following gene: 170751695

Centisome position: 92.7

GC content: 67.96

Gene sequence:

>543_bases
ATGAACGCGATGAACACCCACTATCCCGAGCCCGTCCGCGTCGAGCCGGTGAACCGGCACACGCTCGCGGTGATCGTCGA
CAACGAGCCCGGCGTGCTCGCCCGCATCTCCGGCATGTTCTCCGGTCGCGGCTACAACATCGAGAGCCTGACGGTCTCCG
AGACCGAGGAGGCGCGCCACATCTCCCGCATCACCATCGTGACCGCGGGCACGAACGCCGTGATCGAGCAGATCAAGGCG
CAGCTCGACCGGCTGGTGCCGGTGCACCGGGTGGTGGACCTGACGCTCCAGGGCAACGCCATCGAGCGCGAGATCTGCCT
GGTGAAGGTGAAGGGCGAGGGCGAGCACCGCAGCGAGGCGCTTCGGCTCGCCGCCGCCTTCGGCGCCAAGACGCTCGACG
CCACGCTCAACTCCTTCGTGTTCGAATTGACCGGCGCCACCGAGGAGATCGACCGGTTCGTGCGCCTGATGAGCGTGATC
GGGCTGGTGGAGATCTGCCGGACCGGGATCTCCGCGATGGGGCGCGGGGCGGAGCCGCTCTAA

Upstream 100 bases:

>100_bases
AGGCAAGATGCTGGTGTGAGGGAGGGCGGCCCGGCTCCGTGCCGGGCCGCGATCCGCCGCTGCGGCGGCGTTGGGTCGAA
CGACGAGGACTTGCCCCGCG

Downstream 100 bases:

>100_bases
GCTTCCGACGCGCGGCTCATCGGTGCCGGGGGGAGCCGATCGAGGCCGTCGCGTCGCGCCTGAGTTCGTCGATCAAGGAC
CACCCATGACCGCCCGTACG

Product: acetolactate synthase, small subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNAMNTHYPEPVRVEPVNRHTLAVIVDNEPGVLARISGMFSGRGYNIESLTVSETEEARHISRITIVTAGTNAVIEQIKA
QLDRLVPVHRVVDLTLQGNAIEREICLVKVKGEGEHRSEALRLAAAFGAKTLDATLNSFVFELTGATEEIDRFVRLMSVI
GLVEICRTGISAMGRGAEPL

Sequences:

>Translated_180_residues
MNAMNTHYPEPVRVEPVNRHTLAVIVDNEPGVLARISGMFSGRGYNIESLTVSETEEARHISRITIVTAGTNAVIEQIKA
QLDRLVPVHRVVDLTLQGNAIEREICLVKVKGEGEHRSEALRLAAAFGAKTLDATLNSFVFELTGATEEIDRFVRLMSVI
GLVEICRTGISAMGRGAEPL
>Mature_180_residues
MNAMNTHYPEPVRVEPVNRHTLAVIVDNEPGVLARISGMFSGRGYNIESLTVSETEEARHISRITIVTAGTNAVIEQIKA
QLDRLVPVHRVVDLTLQGNAIEREICLVKVKGEGEHRSEALRLAAAFGAKTLDATLNSFVFELTGATEEIDRFVRLMSVI
GLVEICRTGISAMGRGAEPL

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=159, Percent_Identity=42.1383647798742, Blast_Score=118, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319837, Length=216, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 19647; Mature: 19647

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAMNTHYPEPVRVEPVNRHTLAVIVDNEPGVLARISGMFSGRGYNIESLTVSETEEARH
CCCCCCCCCCCEEEEECCCEEEEEEEECCCCEEEEEEHHCCCCCCCEEEEEECCCHHHHH
ISRITIVTAGTNAVIEQIKAQLDRLVPVHRVVDLTLQGNAIEREICLVKVKGEGEHRSEA
EEEEEEEECCCHHHHHHHHHHHHHCCCHHHHEEEEECCCCEEEEEEEEEEECCCCHHHHH
LRLAAAFGAKTLDATLNSFVFELTGATEEIDRFVRLMSVIGLVEICRTGISAMGRGAEPL
HHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAMNTHYPEPVRVEPVNRHTLAVIVDNEPGVLARISGMFSGRGYNIESLTVSETEEARH
CCCCCCCCCCCEEEEECCCEEEEEEEECCCCEEEEEEHHCCCCCCCEEEEEECCCHHHHH
ISRITIVTAGTNAVIEQIKAQLDRLVPVHRVVDLTLQGNAIEREICLVKVKGEGEHRSEA
EEEEEEEECCCHHHHHHHHHHHHHCCCHHHHEEEEECCCCEEEEEEEEEEECCCCHHHHH
LRLAAAFGAKTLDATLNSFVFELTGATEEIDRFVRLMSVIGLVEICRTGISAMGRGAEPL
HHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]