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The map label for this gene is aroQ

Identifier: 170751689

GI number: 170751689

Start: 5628080

End: 5628529

Strand: Direct

Name: aroQ

Synonym: Mrad2831_5319

Alternate gene names: 170751689

Gene position: 5628080-5628529 (Clockwise)

Preceding gene: 170751686

Following gene: 170751690

Centisome position: 92.6

GC content: 69.11

Gene sequence:

>450_bases
ATGAACGACACCGTCCTGGTCCTGAACGGGCCGAACCTGAACCTGCTCGGCAAGCGCCAGCCGGAGATCTACGGCCGCGA
GACCCTGGCCGACGTCGAGGCCCTGTGCCGCGAGACCGCCGCGGGCTTCGGCCTCGCGGTCGATTTCCGGCAGAGCAACG
CCGAGCACGCGCTGATCGACGCGATCCACGAATTTCGGGTCGGCTCGGCCGGGATCGTCATCAACGCGGGCGCCTACACG
CACACCTCGGTGGCGCTCCTCGACGCGCTGAACACCTGCGAGGTGCCGGTGATCGAGTGCCACATCTCGAACGTCCACCG
GCGCGAGGCTTTCCGCCACCACTCCTACATCTCCCTCGCGGCCACGTCCGTGCTGGCGGGGTTCGGCACGCACGGCTACG
CCCTGGCGATCCGGCACCTCGCGCATCTGCGGGCCGGCAGACCTGCTTGA

Upstream 100 bases:

>100_bases
GGCCGGATGACAGCCGCGACCCGTGTCGTGCCGGACCCGTGCCGCGCCGGACTTGAGTCTTGCCGGCGGTTGTCGCACCT
CTCGGCCCGCGAGGCACACG

Downstream 100 bases:

>100_bases
GGCGCGGATAGCGCCGCGATCAGGGTTGACGCTGGCGGAGACAGGGGGGAGGAGGGCGGTCAGGCCCTTATTCAACGCGT
TCTCCCCGGCCGGACCGGTC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNDTVLVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGLAVDFRQSNAEHALIDAIHEFRVGSAGIVINAGAYT
HTSVALLDALNTCEVPVIECHISNVHRREAFRHHSYISLAATSVLAGFGTHGYALAIRHLAHLRAGRPA

Sequences:

>Translated_149_residues
MNDTVLVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGLAVDFRQSNAEHALIDAIHEFRVGSAGIVINAGAYT
HTSVALLDALNTCEVPVIECHISNVHRREAFRHHSYISLAATSVLAGFGTHGYALAIRHLAHLRAGRPA
>Mature_149_residues
MNDTVLVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGLAVDFRQSNAEHALIDAIHEFRVGSAGIVINAGAYT
HTSVALLDALNTCEVPVIECHISNVHRREAFRHHSYISLAATSVLAGFGTHGYALAIRHLAHLRAGRPA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_METRJ (B1LXE5)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001757949.1
- ProteinModelPortal:   B1LXE5
- SMR:   B1LXE5
- GeneID:   6141391
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_5319
- HOGENOM:   HBG284657
- OMA:   EFRQTNH
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16059; Mature: 16059

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTVLVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGLAVDFRQSNAEHALID
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
AIHEFRVGSAGIVINAGAYTHTSVALLDALNTCEVPVIECHISNVHRREAFRHHSYISLA
HHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHH
ATSVLAGFGTHGYALAIRHLAHLRAGRPA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDTVLVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGLAVDFRQSNAEHALID
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
AIHEFRVGSAGIVINAGAYTHTSVALLDALNTCEVPVIECHISNVHRREAFRHHSYISLA
HHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHH
ATSVLAGFGTHGYALAIRHLAHLRAGRPA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA