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The map label for this gene is ampC [C]

Identifier: 170751662

GI number: 170751662

Start: 5608305

End: 5609252

Strand: Reverse

Name: ampC [C]

Synonym: Mrad2831_5292

Alternate gene names: 170751662

Gene position: 5609252-5608305 (Counterclockwise)

Preceding gene: 170751663

Following gene: 170751661

Centisome position: 92.29

GC content: 67.41

Gene sequence:

>948_bases
GTGGATGAGAGCACGCTGTTCGAGATCGGCTCGATCAGCAAAACCATCACCGTGGCGCTGGCTGCCTACGCCGCGGAGAC
GGGGGCGCTCCGGTGGGATGCTGCGCCCGGCCGCTACATCACCGAACTGAAGGCCAGCGCCCTCGACCGGGTGTCGCTCC
TCAACCTTGCGACGCACACCACCGGGGGTATGCCGCTGCAACTCTCCGACGACGTGAAGATCGACGCCGACCTCATCGCC
TACTTCCGCAAGTGGACACCGCCGTCGCCGCCGGGGAGCGTGCGCACCTACGCCAATCCGAGTATCGGTCTCCTCGGGCT
GGTGACGGCCCGTGCGATGAAGGGCCAGTTCGCCGTGCTCGTGCGCGAACACGTCACGAGGCCCCTCGGCCTTCAGCGCA
CTTTCCACGACGTGCCGAAGGCCGAGCAGCCGCACTACGCTCAGGGCTACACGCGGGACGGCAAACCCGTCCGGGTCTCG
ATGGCCCCTCTCGCCACCGAAGCCTACGGCCTGCGCACGACGGCGAGGGACCTGCTGCGGTTCGTGGAGGCGCAACTCGG
GCTGATCGACGTGAGCCCGACGCTGCAACGTGCGCTCTCGGCGACGCAGGTCGGTCGCTTCCTGGCCGGGCCGATGACGC
AGGCGCTGATCTGGGAGTGGTATCCGCTCCCGGTTTCGGATGATGATCTTGCGGTCGGCAACGGCGACGCGATGGTACTC
AAGCCCACGCCGGTCACGCGCCTCGACCCACCACGCGCACCTCCGGCCGACAGCCTCGTCACGAAAACGGGGGCAACCAA
CGGGTTCGGGGCCTACGTGGCCTTTATCCCCGGCCGCAAAATCGGGCTTGTGCTGATGGCGAACCGCAATCATCCGACTG
CCGTGCGGCTCACGCTCGCCAAGCAGGTCTTCACGGCGCTGAACGTACAGGGGATACCCGCGCAGTAG

Upstream 100 bases:

>100_bases
TGCCTCGCGTTCAAGGCGTCGGCTCGACTGCACCTGGTTTATGTAACCGTACAGATAGAGCTTCAGAGGCGTCGCCGGAT
GGTAGCCGGGCCGCCCGGTT

Downstream 100 bases:

>100_bases
ACGGCACGGAGGCCGATCCCGATCGTGGGCTTTCCATCCCGAGCCGAAGTTGCGGGCCCGCCGAAGGATGACCGCTTTCG
GGAAGCGCTGACGCGGGCCC

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MDESTLFEIGSISKTITVALAAYAAETGALRWDAAPGRYITELKASALDRVSLLNLATHTTGGMPLQLSDDVKIDADLIA
YFRKWTPPSPPGSVRTYANPSIGLLGLVTARAMKGQFAVLVREHVTRPLGLQRTFHDVPKAEQPHYAQGYTRDGKPVRVS
MAPLATEAYGLRTTARDLLRFVEAQLGLIDVSPTLQRALSATQVGRFLAGPMTQALIWEWYPLPVSDDDLAVGNGDAMVL
KPTPVTRLDPPRAPPADSLVTKTGATNGFGAYVAFIPGRKIGLVLMANRNHPTAVRLTLAKQVFTALNVQGIPAQ

Sequences:

>Translated_315_residues
MDESTLFEIGSISKTITVALAAYAAETGALRWDAAPGRYITELKASALDRVSLLNLATHTTGGMPLQLSDDVKIDADLIA
YFRKWTPPSPPGSVRTYANPSIGLLGLVTARAMKGQFAVLVREHVTRPLGLQRTFHDVPKAEQPHYAQGYTRDGKPVRVS
MAPLATEAYGLRTTARDLLRFVEAQLGLIDVSPTLQRALSATQVGRFLAGPMTQALIWEWYPLPVSDDDLAVGNGDAMVL
KPTPVTRLDPPRAPPADSLVTKTGATNGFGAYVAFIPGRKIGLVLMANRNHPTAVRLTLAKQVFTALNVQGIPAQ
>Mature_315_residues
MDESTLFEIGSISKTITVALAAYAAETGALRWDAAPGRYITELKASALDRVSLLNLATHTTGGMPLQLSDDVKIDADLIA
YFRKWTPPSPPGSVRTYANPSIGLLGLVTARAMKGQFAVLVREHVTRPLGLQRTFHDVPKAEQPHYAQGYTRDGKPVRVS
MAPLATEAYGLRTTARDLLRFVEAQLGLIDVSPTLQRALSATQVGRFLAGPMTQALIWEWYPLPVSDDDLAVGNGDAMVL
KPTPVTRLDPPRAPPADSLVTKTGATNGFGAYVAFIPGRKIGLVLMANRNHPTAVRLTLAKQVFTALNVQGIPAQ

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=307, Percent_Identity=40.0651465798046, Blast_Score=229, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 33920; Mature: 33920

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESTLFEIGSISKTITVALAAYAAETGALRWDAAPGRYITELKASALDRVSLLNLATHT
CCCCCEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
TGGMPLQLSDDVKIDADLIAYFRKWTPPSPPGSVRTYANPSIGLLGLVTARAMKGQFAVL
CCCCEEEECCCCEECHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHH
VREHVTRPLGLQRTFHDVPKAEQPHYAQGYTRDGKPVRVSMAPLATEAYGLRTTARDLLR
HHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHH
FVEAQLGLIDVSPTLQRALSATQVGRFLAGPMTQALIWEWYPLPVSDDDLAVGNGDAMVL
HHHHHCCEEECCHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCCCEEECCCCEEEE
KPTPVTRLDPPRAPPADSLVTKTGATNGFGAYVAFIPGRKIGLVLMANRNHPTAVRLTLA
CCCCCCCCCCCCCCCCCHHEECCCCCCCCCEEEEEECCCEEEEEEEECCCCCCEEEEHHH
KQVFTALNVQGIPAQ
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MDESTLFEIGSISKTITVALAAYAAETGALRWDAAPGRYITELKASALDRVSLLNLATHT
CCCCCEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
TGGMPLQLSDDVKIDADLIAYFRKWTPPSPPGSVRTYANPSIGLLGLVTARAMKGQFAVL
CCCCEEEECCCCEECHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHH
VREHVTRPLGLQRTFHDVPKAEQPHYAQGYTRDGKPVRVSMAPLATEAYGLRTTARDLLR
HHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHH
FVEAQLGLIDVSPTLQRALSATQVGRFLAGPMTQALIWEWYPLPVSDDDLAVGNGDAMVL
HHHHHCCEEECCHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCCCEEECCCCEEEE
KPTPVTRLDPPRAPPADSLVTKTGATNGFGAYVAFIPGRKIGLVLMANRNHPTAVRLTLA
CCCCCCCCCCCCCCCCCHHEECCCCCCCCCEEEEEECCCEEEEEEEECCCCCCEEEEHHH
KQVFTALNVQGIPAQ
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8703429 [H]