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The map label for this gene is hipO [H]

Identifier: 170751212

GI number: 170751212

Start: 5159111

End: 5160265

Strand: Direct

Name: hipO [H]

Synonym: Mrad2831_4829

Alternate gene names: 170751212

Gene position: 5159111-5160265 (Clockwise)

Preceding gene: 170751211

Following gene: 170751216

Centisome position: 84.88

GC content: 74.11

Gene sequence:

>1155_bases
ATGGGCATCGAGGCGGAGACCGTGGAGCGGATGGTCGCGTGGCGGCGCGACCTGCACGCCCACCCCGAGCTGGCCTTCCA
GGAGGTCCGCACGGCGGAGCTCGTCGCCCGGGAACTGGCCGCCTGCGGCCTCTCGGTGAAGACCGGGCTCGGCCGCACCG
GCGTGGTCGGGACCCTGAGCCGGGGCGACGGGCCGACCGTCGGCCTGCGGGCCGACATGGACGCCCTGCCCATCCAGGAG
GCGACGGGCGCGAGTTACGCCTCCCGGACGCCCGGCGTGATGCATGCCTGCGGGCACGACGGCCACGTGGCGATGCTGCT
CGGCGCGGCGCGGCACCTCGCGTCGCGCACCGACCTCTCCGGCACGGTGCACTTCATCTTCCAGCCGGCGGAGGAGTGCG
AGGGCGGCGGGCGCGCCATGGTCGAGGACGGCCTGTTCCGGCTGTTCCCGTGCGATTCCGTCTACGGCCTGCACAACTGG
CCGGGCCTGCCGCTGGGGACCTTCGCGACCCGGGTCGGCGCCATCATGGCCTCCCTCGACACGTTCGAGATCACGGTCGC
CGGGTTCGGGACCCACGCGGCCATGCCGGAGCGCGGCACCGACACGCTGGTGGTCGCTTCCGAGATCGTCCTCGCCCTGC
AGACCATCGTGAGCCGCCGGATCGCCCCGACGGACCCGGTCGTGCTCAGCGTCACGCAGATCCACGGCGGCGACGCCTAC
AACGTCATCCCCGACCGCGCGGTCATCCGCGGCACGGTCCGGTGCCTGGACGAGGCCGTGCGCAAGCGCGTCGCGGAGCT
CGTCGCGGCCATCGCGGGCGGGACGGCCGGCACGCACGGCGCCCGCGCCGAGGTGGACTACCGGTTCGGGTACCCCGCCA
CCGTCAACACCGCCGACGCCGTCGGCACCGCCCTGGAGGCGGCCGGGACCGTCCCGGACATCACCGCGCGCCGCGGCGAG
GTCGGACCCTCCATGGCGTCGGAGGATTTCGCCTACATGCTCCTGGCCTGTCCCGGCGCCTATGCCTGGATCGGGACCGA
CGGGGCGCAGCGGAGCCTGCCGCTCCACAATCCGGGCTACGACTTCAACGACGAGGCGCTGCCGGTCGGCGCCGCGTACT
GGGCCGCGCTGGCGTCGCACAGCCTCAGGCCGTGA

Upstream 100 bases:

>100_bases
TCATGCACGCCCCGCTGGGGTGAACCGCCGCGCCGATCGGCGTAGGGTCCGGACGGGGGATCGAGGCGCTCCGGCAGCGC
CGGCATTTGAGAGAGGTCGC

Downstream 100 bases:

>100_bases
GGCGAGCGCTCTGAGGGACCGCCCGCGCCGGAGGCGCGGGCGGTCCCGATGGCGGGTCTCAGGCCGCCATCGGCCCGTAG
CGCCGGTGACCCTTCACGTC

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MGIEAETVERMVAWRRDLHAHPELAFQEVRTAELVARELAACGLSVKTGLGRTGVVGTLSRGDGPTVGLRADMDALPIQE
ATGASYASRTPGVMHACGHDGHVAMLLGAARHLASRTDLSGTVHFIFQPAEECEGGGRAMVEDGLFRLFPCDSVYGLHNW
PGLPLGTFATRVGAIMASLDTFEITVAGFGTHAAMPERGTDTLVVASEIVLALQTIVSRRIAPTDPVVLSVTQIHGGDAY
NVIPDRAVIRGTVRCLDEAVRKRVAELVAAIAGGTAGTHGARAEVDYRFGYPATVNTADAVGTALEAAGTVPDITARRGE
VGPSMASEDFAYMLLACPGAYAWIGTDGAQRSLPLHNPGYDFNDEALPVGAAYWAALASHSLRP

Sequences:

>Translated_384_residues
MGIEAETVERMVAWRRDLHAHPELAFQEVRTAELVARELAACGLSVKTGLGRTGVVGTLSRGDGPTVGLRADMDALPIQE
ATGASYASRTPGVMHACGHDGHVAMLLGAARHLASRTDLSGTVHFIFQPAEECEGGGRAMVEDGLFRLFPCDSVYGLHNW
PGLPLGTFATRVGAIMASLDTFEITVAGFGTHAAMPERGTDTLVVASEIVLALQTIVSRRIAPTDPVVLSVTQIHGGDAY
NVIPDRAVIRGTVRCLDEAVRKRVAELVAAIAGGTAGTHGARAEVDYRFGYPATVNTADAVGTALEAAGTVPDITARRGE
VGPSMASEDFAYMLLACPGAYAWIGTDGAQRSLPLHNPGYDFNDEALPVGAAYWAALASHSLRP
>Mature_383_residues
GIEAETVERMVAWRRDLHAHPELAFQEVRTAELVARELAACGLSVKTGLGRTGVVGTLSRGDGPTVGLRADMDALPIQEA
TGASYASRTPGVMHACGHDGHVAMLLGAARHLASRTDLSGTVHFIFQPAEECEGGGRAMVEDGLFRLFPCDSVYGLHNWP
GLPLGTFATRVGAIMASLDTFEITVAGFGTHAAMPERGTDTLVVASEIVLALQTIVSRRIAPTDPVVLSVTQIHGGDAYN
VIPDRAVIRGTVRCLDEAVRKRVAELVAAIAGGTAGTHGARAEVDYRFGYPATVNTADAVGTALEAAGTVPDITARRGEV
GPSMASEDFAYMLLACPGAYAWIGTDGAQRSLPLHNPGYDFNDEALPVGAAYWAALASHSLRP

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=414, Percent_Identity=28.743961352657, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 40323; Mature: 40192

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEAETVERMVAWRRDLHAHPELAFQEVRTAELVARELAACGLSVKTGLGRTGVVGTLS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEC
RGDGPTVGLRADMDALPIQEATGASYASRTPGVMHACGHDGHVAMLLGAARHLASRTDLS
CCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
GTVHFIFQPAEECEGGGRAMVEDGLFRLFPCDSVYGLHNWPGLPLGTFATRVGAIMASLD
CEEEEEECCHHHCCCCCCEEHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TFEITVAGFGTHAAMPERGTDTLVVASEIVLALQTIVSRRIAPTDPVVLSVTQIHGGDAY
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCC
NVIPDRAVIRGTVRCLDEAVRKRVAELVAAIAGGTAGTHGARAEVDYRFGYPATVNTADA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHH
VGTALEAAGTVPDITARRGEVGPSMASEDFAYMLLACPGAYAWIGTDGAQRSLPLHNPGY
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCEEEEECCCCCCCCCCCCCCC
DFNDEALPVGAAYWAALASHSLRP
CCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GIEAETVERMVAWRRDLHAHPELAFQEVRTAELVARELAACGLSVKTGLGRTGVVGTLS
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEC
RGDGPTVGLRADMDALPIQEATGASYASRTPGVMHACGHDGHVAMLLGAARHLASRTDLS
CCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
GTVHFIFQPAEECEGGGRAMVEDGLFRLFPCDSVYGLHNWPGLPLGTFATRVGAIMASLD
CEEEEEECCHHHCCCCCCEEHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TFEITVAGFGTHAAMPERGTDTLVVASEIVLALQTIVSRRIAPTDPVVLSVTQIHGGDAY
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCC
NVIPDRAVIRGTVRCLDEAVRKRVAELVAAIAGGTAGTHGARAEVDYRFGYPATVNTADA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHH
VGTALEAAGTVPDITARRGEVGPSMASEDFAYMLLACPGAYAWIGTDGAQRSLPLHNPGY
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCEEEEECCCCCCCCCCCCCCC
DFNDEALPVGAAYWAALASHSLRP
CCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]