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The map label for this gene is yciR [C]

Identifier: 170751167

GI number: 170751167

Start: 5100077

End: 5102434

Strand: Direct

Name: yciR [C]

Synonym: Mrad2831_4784

Alternate gene names: 170751167

Gene position: 5100077-5102434 (Clockwise)

Preceding gene: 170751164

Following gene: 170751174

Centisome position: 83.91

GC content: 63.06

Gene sequence:

>2358_bases
ATGATCTATGGTGCTGCCGGTCTAGCCGCCGACCATTCGCGCGCGTTTGTTTTCACTGCTCTTGCTATCTGCCTCGTGGC
CGGGTGGCTGGTCGCCGCACTCATGCGCACGATCAGCGAGGCCGATCTGGCTCAGCGGTACCGCTGGCTGGCGGGAACGG
CAGTCGTGGCCGGCTTGGGCGTCTGGACAACCCATTTCGTCGCCATGCTGGGCTACCGGCCCGATATGGTGCTGGGCTTT
GATGACACGACCACCATCTTCTCGGCGCTGGTCGCCATCTTGGTCGTGGGGCTGCCGCTGGCCCTGGCGAGGCTCTTTCC
GTCTTGGCGTATCCGGACCCTGGCTGGCGCGGCCGCCGGGTTCGGTATCGGCGCGATGCATCACGCCGGCATGGCAGCGC
TCGAGGGATGCCAGCAGACCCATTCGCCGGTCATGAACGTTCTGGCCGCAGGTATCGGTGCTTGCAGTCTCGCGCTGGTT
TGTGGCCTGCCGCGACGCTTGGCGACGCCTTGGGTGGTCTGCGCTCTTTTCACCCTGGCAGTCACCGGTACTCACTTCGT
CGCGATTGCCGGCACGACGCTGGTGCCCATCCAGGGCTATCGCGGCTTGCCGAACGAAAATATCGTGCTCAGCATCTTGA
CCACGGGAGGCGCTGCTGTCCTCTTCCTCGGGGCATTCCTGACGATCCTCGCGGCACGACGCTTCGACGCCCAAGAGCGT
GCCCATTCATCAATTCTGAGAACCGCTCTCGACAATATGTCGAATGGGTTGCTGTATCTGGACCCGGCTGAACGCGTGCG
CCTGTACAACCGGCGCTACCTGGAGATCTATCACATCCCTGTCGATGTCGATCTTACGGGCATGACCATCGATCAGATCA
TCGACCTTGTCGGCTATCGTCACGGCTGGACCGCAGAGCGGCGAGAGGCGGCGCGCCGGCGGGTCGACGACTGGCGGAGC
GTCAAGAACTCCAAACAGATCGACTACCCGCTGGAGGACGGCCGCGTTCTACAGGTCGAGATCCGCCCCATCGAGGACGG
CGGCAATGTCGTCACCTTCGACGACGTGACCAAAGAGCGCGAGGCGCAGCGCCGGATTGCGGAATTGGCCTTCTGCGATC
CCCTGACCAAGCTCGCCAATCGACGCGCTTTGAGTGCTCGGTTGGAGCACGATTTTACACCTAAGCGCGTCGTCAAGCTC
CTGCTGATCGATCTCGATCGTTTCAAGCAGGTTAACGATACCTACGGTCACGTGGTCGGCGACCAGCTCCTCATCCAGGT
CGCCAACAGGCTGAGGACGATCGCGGGACCGGACGGTTTCGTAGCCCGGCTCGGCGGTGACGAGATGGCGGTGCTGGTCT
ACGGCGATCAGACCCAGGCCATGGCTGTCGCCACCGCGGTGATCGAGGCACTGGCCCTGCCGTATGGGATCGACGACCTC
ACTGTGTCGATCGGCTGCAGCATCGGTCTGTGCTGCACGGATGACGCGCAGGATGCGATCGAACTCATGCAGTTCTCGGA
CATCGCGCTCTACGAGTCGAAGCGCCAGGGTCGAGGTCGAACGAGCTGCTACACGCCCGACATGTTGAGGACCGTCGCCG
ATCGGGTTCAGCTGGAAACGGACATGCGTGCCGCGATCGAACGGGGAGAGATGTATCTGGCCTTTCAGCCGGTGATCGCC
CTCGTCGACGACCGGATCATCGGCTACGAGGCGTTGATCCGCTGGGATCACCCGAAGCTCGGAGCCGTGTCTCCGGCCCG
GTTCATTCCGTTGGCAGAGGAGACCGGGCAGATCATTCCGATCGGAGCCTGGGTGTTGCAGGAGGCGTGCCGGCAGGCCG
CGCGATTGCCGAACGATGTCTACGTCGCGGTCAACGTTTCACCGGTTCAGTTTCGCTCTCCGCAGCTCTTGTCTGATCTC
ACGCAGGCTCTGGCCAGAAGTGGCCTGCCGGCCGAGCGTTTGGAGATCGAACTCACGGAAACAGCGATCGTCGAGGACGG
CCCTCGGATCGCCAAGATCCTGGCCGCTATCCGCCGCCTCGGCGTGACGGTCGCGATGGATGATTTCGGCACGGGTTACT
CGTCGCTCGCCCATCTGCGCGACTTTCCGCTCGACCGCATCAAGGTGGACCGTTCCTTCGTAGCCACGGCCGAGACGGAC
CGTCACTCGTTGGCGGTGCTGAAAGGCATCATGCATATCGCGAAGGCGCTGGATGTCGTGCTGCAAGCCGAGGGCGTAGA
GACGCCGTCGCAGCTCGCCCTCATGCGCGAGATTGGTTGCGATGCGATCCAGGGCTACCTCATTGGACGGCCGCAGCGAT
TGGTGGACAGCACTGTGCCGATGGCTCTCTCGGCCTAG

Upstream 100 bases:

>100_bases
CGTGACGGGAATGTCAGGCTCAAGGCCGGGCCTGTTATGAACGGTATTTTCATCGTCTTCTTTCATGCCGGCTTCAGAGG
GCGGCACGTACAGGCAAGAC

Downstream 100 bases:

>100_bases
CTTCGCGACCGAGTAATGAGCGTCCGCTTCGCGAGTGCGCATGAGCCGTAGGCGGCGGGCCGGATAGGGGCGGAAACGGG
AGCCGCTCCGGGGGGGCAAG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MIYGAAGLAADHSRAFVFTALAICLVAGWLVAALMRTISEADLAQRYRWLAGTAVVAGLGVWTTHFVAMLGYRPDMVLGF
DDTTTIFSALVAILVVGLPLALARLFPSWRIRTLAGAAAGFGIGAMHHAGMAALEGCQQTHSPVMNVLAAGIGACSLALV
CGLPRRLATPWVVCALFTLAVTGTHFVAIAGTTLVPIQGYRGLPNENIVLSILTTGGAAVLFLGAFLTILAARRFDAQER
AHSSILRTALDNMSNGLLYLDPAERVRLYNRRYLEIYHIPVDVDLTGMTIDQIIDLVGYRHGWTAERREAARRRVDDWRS
VKNSKQIDYPLEDGRVLQVEIRPIEDGGNVVTFDDVTKEREAQRRIAELAFCDPLTKLANRRALSARLEHDFTPKRVVKL
LLIDLDRFKQVNDTYGHVVGDQLLIQVANRLRTIAGPDGFVARLGGDEMAVLVYGDQTQAMAVATAVIEALALPYGIDDL
TVSIGCSIGLCCTDDAQDAIELMQFSDIALYESKRQGRGRTSCYTPDMLRTVADRVQLETDMRAAIERGEMYLAFQPVIA
LVDDRIIGYEALIRWDHPKLGAVSPARFIPLAEETGQIIPIGAWVLQEACRQAARLPNDVYVAVNVSPVQFRSPQLLSDL
TQALARSGLPAERLEIELTETAIVEDGPRIAKILAAIRRLGVTVAMDDFGTGYSSLAHLRDFPLDRIKVDRSFVATAETD
RHSLAVLKGIMHIAKALDVVLQAEGVETPSQLALMREIGCDAIQGYLIGRPQRLVDSTVPMALSA

Sequences:

>Translated_785_residues
MIYGAAGLAADHSRAFVFTALAICLVAGWLVAALMRTISEADLAQRYRWLAGTAVVAGLGVWTTHFVAMLGYRPDMVLGF
DDTTTIFSALVAILVVGLPLALARLFPSWRIRTLAGAAAGFGIGAMHHAGMAALEGCQQTHSPVMNVLAAGIGACSLALV
CGLPRRLATPWVVCALFTLAVTGTHFVAIAGTTLVPIQGYRGLPNENIVLSILTTGGAAVLFLGAFLTILAARRFDAQER
AHSSILRTALDNMSNGLLYLDPAERVRLYNRRYLEIYHIPVDVDLTGMTIDQIIDLVGYRHGWTAERREAARRRVDDWRS
VKNSKQIDYPLEDGRVLQVEIRPIEDGGNVVTFDDVTKEREAQRRIAELAFCDPLTKLANRRALSARLEHDFTPKRVVKL
LLIDLDRFKQVNDTYGHVVGDQLLIQVANRLRTIAGPDGFVARLGGDEMAVLVYGDQTQAMAVATAVIEALALPYGIDDL
TVSIGCSIGLCCTDDAQDAIELMQFSDIALYESKRQGRGRTSCYTPDMLRTVADRVQLETDMRAAIERGEMYLAFQPVIA
LVDDRIIGYEALIRWDHPKLGAVSPARFIPLAEETGQIIPIGAWVLQEACRQAARLPNDVYVAVNVSPVQFRSPQLLSDL
TQALARSGLPAERLEIELTETAIVEDGPRIAKILAAIRRLGVTVAMDDFGTGYSSLAHLRDFPLDRIKVDRSFVATAETD
RHSLAVLKGIMHIAKALDVVLQAEGVETPSQLALMREIGCDAIQGYLIGRPQRLVDSTVPMALSA
>Mature_785_residues
MIYGAAGLAADHSRAFVFTALAICLVAGWLVAALMRTISEADLAQRYRWLAGTAVVAGLGVWTTHFVAMLGYRPDMVLGF
DDTTTIFSALVAILVVGLPLALARLFPSWRIRTLAGAAAGFGIGAMHHAGMAALEGCQQTHSPVMNVLAAGIGACSLALV
CGLPRRLATPWVVCALFTLAVTGTHFVAIAGTTLVPIQGYRGLPNENIVLSILTTGGAAVLFLGAFLTILAARRFDAQER
AHSSILRTALDNMSNGLLYLDPAERVRLYNRRYLEIYHIPVDVDLTGMTIDQIIDLVGYRHGWTAERREAARRRVDDWRS
VKNSKQIDYPLEDGRVLQVEIRPIEDGGNVVTFDDVTKEREAQRRIAELAFCDPLTKLANRRALSARLEHDFTPKRVVKL
LLIDLDRFKQVNDTYGHVVGDQLLIQVANRLRTIAGPDGFVARLGGDEMAVLVYGDQTQAMAVATAVIEALALPYGIDDL
TVSIGCSIGLCCTDDAQDAIELMQFSDIALYESKRQGRGRTSCYTPDMLRTVADRVQLETDMRAAIERGEMYLAFQPVIA
LVDDRIIGYEALIRWDHPKLGAVSPARFIPLAEETGQIIPIGAWVLQEACRQAARLPNDVYVAVNVSPVQFRSPQLLSDL
TQALARSGLPAERLEIELTETAIVEDGPRIAKILAAIRRLGVTVAMDDFGTGYSSLAHLRDFPLDRIKVDRSFVATAETD
RHSLAVLKGIMHIAKALDVVLQAEGVETPSQLALMREIGCDAIQGYLIGRPQRLVDSTVPMALSA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=424, Percent_Identity=34.9056603773585, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI87081921, Length=424, Percent_Identity=34.9056603773585, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI226510982, Length=410, Percent_Identity=26.3414634146341, Blast_Score=160, Evalue=4e-40,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=35.5371900826446, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=33.469387755102, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1788849, Length=434, Percent_Identity=26.2672811059908, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081980, Length=247, Percent_Identity=35.6275303643725, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1790496, Length=232, Percent_Identity=33.1896551724138, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787055, Length=249, Percent_Identity=31.7269076305221, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1786507, Length=231, Percent_Identity=32.9004329004329, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI87081743, Length=235, Percent_Identity=32.7659574468085, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1788381, Length=442, Percent_Identity=27.8280542986425, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI87082096, Length=420, Percent_Identity=23.5714285714286, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788956, Length=153, Percent_Identity=33.9869281045752, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=32.5966850828729, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787056, Length=193, Percent_Identity=29.5336787564767, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1787802, Length=170, Percent_Identity=35.2941176470588, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=33.1395348837209, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081881, Length=342, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=31.7647058823529, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787410, Length=222, Percent_Identity=23.4234234234234, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=30.952380952381, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1787816, Length=154, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788085, Length=182, Percent_Identity=29.1208791208791, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082007, Length=169, Percent_Identity=27.810650887574, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 85627; Mature: 85627

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50924 MHYT ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGAAGLAADHSRAFVFTALAICLVAGWLVAALMRTISEADLAQRYRWLAGTAVVAGLG
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWTTHFVAMLGYRPDMVLGFDDTTTIFSALVAILVVGLPLALARLFPSWRIRTLAGAAAG
HHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
FGIGAMHHAGMAALEGCQQTHSPVMNVLAAGIGACSLALVCGLPRRLATPWVVCALFTLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VTGTHFVAIAGTTLVPIQGYRGLPNENIVLSILTTGGAAVLFLGAFLTILAARRFDAQER
HCCCEEEEEECCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHH
AHSSILRTALDNMSNGLLYLDPAERVRLYNRRYLEIYHIPVDVDLTGMTIDQIIDLVGYR
HHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCEEEEEEEEEEEEECCCCHHHHHHHHCCC
HGWTAERREAARRRVDDWRSVKNSKQIDYPLEDGRVLQVEIRPIEDGGNVVTFDDVTKER
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECHHHHHH
EAQRRIAELAFCDPLTKLANRRALSARLEHDFTPKRVVKLLLIDLDRFKQVNDTYGHVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
DQLLIQVANRLRTIAGPDGFVARLGGDEMAVLVYGDQTQAMAVATAVIEALALPYGIDDL
HHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCE
TVSIGCSIGLCCTDDAQDAIELMQFSDIALYESKRQGRGRTSCYTPDMLRTVADRVQLET
EEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DMRAAIERGEMYLAFQPVIALVDDRIIGYEALIRWDHPKLGAVSPARFIPLAEETGQIIP
HHHHHHHCCCEEEEHHHHHHHHCCCCCCHHHEEEECCCCCCCCCCHHCCCCHHHCCCEEE
IGAWVLQEACRQAARLPNDVYVAVNVSPVQFRSPQLLSDLTQALARSGLPAERLEIELTE
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHEEEEEEH
TAIVEDGPRIAKILAAIRRLGVTVAMDDFGTGYSSLAHLRDFPLDRIKVDRSFVATAETD
HHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHEEECCHHEEECCCC
RHSLAVLKGIMHIAKALDVVLQAEGVETPSQLALMREIGCDAIQGYLIGRPQRLVDSTVP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHCCCCHHHHHCCCC
MALSA
CCCCC
>Mature Secondary Structure
MIYGAAGLAADHSRAFVFTALAICLVAGWLVAALMRTISEADLAQRYRWLAGTAVVAGLG
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWTTHFVAMLGYRPDMVLGFDDTTTIFSALVAILVVGLPLALARLFPSWRIRTLAGAAAG
HHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
FGIGAMHHAGMAALEGCQQTHSPVMNVLAAGIGACSLALVCGLPRRLATPWVVCALFTLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VTGTHFVAIAGTTLVPIQGYRGLPNENIVLSILTTGGAAVLFLGAFLTILAARRFDAQER
HCCCEEEEEECCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHH
AHSSILRTALDNMSNGLLYLDPAERVRLYNRRYLEIYHIPVDVDLTGMTIDQIIDLVGYR
HHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCEEEEEEEEEEEEECCCCHHHHHHHHCCC
HGWTAERREAARRRVDDWRSVKNSKQIDYPLEDGRVLQVEIRPIEDGGNVVTFDDVTKER
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECHHHHHH
EAQRRIAELAFCDPLTKLANRRALSARLEHDFTPKRVVKLLLIDLDRFKQVNDTYGHVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
DQLLIQVANRLRTIAGPDGFVARLGGDEMAVLVYGDQTQAMAVATAVIEALALPYGIDDL
HHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCE
TVSIGCSIGLCCTDDAQDAIELMQFSDIALYESKRQGRGRTSCYTPDMLRTVADRVQLET
EEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DMRAAIERGEMYLAFQPVIALVDDRIIGYEALIRWDHPKLGAVSPARFIPLAEETGQIIP
HHHHHHHCCCEEEEHHHHHHHHCCCCCCHHHEEEECCCCCCCCCCHHCCCCHHHCCCEEE
IGAWVLQEACRQAARLPNDVYVAVNVSPVQFRSPQLLSDLTQALARSGLPAERLEIELTE
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHEEEEEEH
TAIVEDGPRIAKILAAIRRLGVTVAMDDFGTGYSSLAHLRDFPLDRIKVDRSFVATAETD
HHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHEEECCHHEEECCCC
RHSLAVLKGIMHIAKALDVVLQAEGVETPSQLALMREIGCDAIQGYLIGRPQRLVDSTVP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHCCCCHHHHHCCCC
MALSA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]