Click here to switch to the map view.

The map label for this gene is mauR [H]

Identifier: 170751151

GI number: 170751151

Start: 5081717

End: 5082577

Strand: Reverse

Name: mauR [H]

Synonym: Mrad2831_4767

Alternate gene names: 170751151

Gene position: 5082577-5081717 (Counterclockwise)

Preceding gene: 170751156

Following gene: 170751150

Centisome position: 83.62

GC content: 64.92

Gene sequence:

>861_bases
ATGGAATGGAGTGACGTCAGAATCTTTCTCGCTATCGCGCGATCCGGCACGCTCGGCGGCGCCGCGCGGTCTCTTCAGAC
AAGCCATCCCACCGTCGGCCGGCGTCTGCGCGCGCTTGAGCAGGCGATCGGTCACACGCTCTTCCAGCGGACTGCGGACG
GTCTCGTTCTGACCGAAGAGGGTCACGGGATCATCGCGCTGGCGGAGCAGATGGAAGAAGGCGCGCTGGCCATGGAGCGC
CGGCTCGCAGGGCAGGAGCAGAACCTCAAGGGCAGTCTCCGCATCTCATCGGCGGACTGGTTCGGGGCCTATGTTCTGCC
TCCCATCCTGGCGGACTTCTCGAGGGCCTACCCCCATGTCGACGTCGAGATCCTGACCGGCACGCGCCTGTTCAACCTCG
CCCAGCGGGAGGCCGACCTCGCTTTCCGTATCGTGCCGTTCAACACCGCCGATGTGGTCCAGCGGCGACTCTTCAGGCTC
GAGTACGGCGTCTACATCGCCGAGGAATCACCTGACCCCAGATACGGCGATGGCACGGGTTTCCGGCTGATCACCCACGA
GACATCGACGGGTCACTTCCCGGACATCGCGTGGCTCATCGAGACTTTCCCCAACGCAAGACCGGTCCTGCGCTCGAACA
ACCGCAACGTCCAAGGGCGCATGTGCAGGCAAGGCGTCGGCATCGCGGTCCTGCCCCGCGTCGTCGGCACGCAGATCCCG
GGTATCCGCAGGCTGGACCTGCCGACGCAACCGCCAGCGCGAGATATCTGGGTGGGATACCACCGGGATCTACGGCGTCT
TCGGCGTCTTCGTGCGTTCGTCTCGACCGTATCGGACCATCTCGGGAACGCGACCGTATGA

Upstream 100 bases:

>100_bases
GACCCGCGCCCTCAGATATCGGCAGCAACCTAGATGGTCAGAATCGTTCTTGAAGTGACAGAACTGTATTCCTAGCGTTC
AGTTTTGTGTGGGTGCCGCG

Downstream 100 bases:

>100_bases
TGGGTCGCCGGGAGAGCGATCAAGGCTGCCGGAGGGCTTGAGCCGAGGCGTCTGATCGCGACGCGCGCGGTGTCGCCGGT
GGAACGCCGGAGCGGGTCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEWSDVRIFLAIARSGTLGGAARSLQTSHPTVGRRLRALEQAIGHTLFQRTADGLVLTEEGHGIIALAEQMEEGALAMER
RLAGQEQNLKGSLRISSADWFGAYVLPPILADFSRAYPHVDVEILTGTRLFNLAQREADLAFRIVPFNTADVVQRRLFRL
EYGVYIAEESPDPRYGDGTGFRLITHETSTGHFPDIAWLIETFPNARPVLRSNNRNVQGRMCRQGVGIAVLPRVVGTQIP
GIRRLDLPTQPPARDIWVGYHRDLRRLRRLRAFVSTVSDHLGNATV

Sequences:

>Translated_286_residues
MEWSDVRIFLAIARSGTLGGAARSLQTSHPTVGRRLRALEQAIGHTLFQRTADGLVLTEEGHGIIALAEQMEEGALAMER
RLAGQEQNLKGSLRISSADWFGAYVLPPILADFSRAYPHVDVEILTGTRLFNLAQREADLAFRIVPFNTADVVQRRLFRL
EYGVYIAEESPDPRYGDGTGFRLITHETSTGHFPDIAWLIETFPNARPVLRSNNRNVQGRMCRQGVGIAVLPRVVGTQIP
GIRRLDLPTQPPARDIWVGYHRDLRRLRRLRAFVSTVSDHLGNATV
>Mature_286_residues
MEWSDVRIFLAIARSGTLGGAARSLQTSHPTVGRRLRALEQAIGHTLFQRTADGLVLTEEGHGIIALAEQMEEGALAMER
RLAGQEQNLKGSLRISSADWFGAYVLPPILADFSRAYPHVDVEILTGTRLFNLAQREADLAFRIVPFNTADVVQRRLFRL
EYGVYIAEESPDPRYGDGTGFRLITHETSTGHFPDIAWLIETFPNARPVLRSNNRNVQGRMCRQGVGIAVLPRVVGTQIP
GIRRLDLPTQPPARDIWVGYHRDLRRLRRLRAFVSTVSDHLGNATV

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=27.5167785234899, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788481, Length=281, Percent_Identity=24.9110320284698, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI157672245, Length=261, Percent_Identity=23.3716475095785, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87081978, Length=235, Percent_Identity=26.8085106382979, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=141, Percent_Identity=26.241134751773, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790208, Length=176, Percent_Identity=28.9772727272727, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31968; Mature: 31968

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSDVRIFLAIARSGTLGGAARSLQTSHPTVGRRLRALEQAIGHTLFQRTADGLVLTEE
CCCCCEEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GHGIIALAEQMEEGALAMERRLAGQEQNLKGSLRISSADWFGAYVLPPILADFSRAYPHV
CCEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
DVEILTGTRLFNLAQREADLAFRIVPFNTADVVQRRLFRLEYGVYIAEESPDPRYGDGTG
EEEEECCHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCC
FRLITHETSTGHFPDIAWLIETFPNARPVLRSNNRNVQGRMCRQGVGIAVLPRVVGTQIP
EEEEEECCCCCCCCHHHHHHHHCCCCCCCEECCCCCCCHHHHHCCCCEEEHHHHHCCCCC
GIRRLDLPTQPPARDIWVGYHRDLRRLRRLRAFVSTVSDHLGNATV
CCEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEWSDVRIFLAIARSGTLGGAARSLQTSHPTVGRRLRALEQAIGHTLFQRTADGLVLTEE
CCCCCEEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GHGIIALAEQMEEGALAMERRLAGQEQNLKGSLRISSADWFGAYVLPPILADFSRAYPHV
CCEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
DVEILTGTRLFNLAQREADLAFRIVPFNTADVVQRRLFRLEYGVYIAEESPDPRYGDGTG
EEEEECCHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCC
FRLITHETSTGHFPDIAWLIETFPNARPVLRSNNRNVQGRMCRQGVGIAVLPRVVGTQIP
EEEEEECCCCCCCCHHHHHHHHCCCCCCCEECCCCCCCHHHHHCCCCEEEHHHHHCCCCC
GIRRLDLPTQPPARDIWVGYHRDLRRLRRLRAFVSTVSDHLGNATV
CCEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]