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The map label for this gene is yciC [H]

Identifier: 170751149

GI number: 170751149

Start: 5078772

End: 5079764

Strand: Reverse

Name: yciC [H]

Synonym: Mrad2831_4765

Alternate gene names: 170751149

Gene position: 5079764-5078772 (Counterclockwise)

Preceding gene: 170751150

Following gene: 170751148

Centisome position: 83.58

GC content: 75.43

Gene sequence:

>993_bases
ATGAGGCGCGGGCTTCCCGCGCCCGCGACGCGCTGCCCGCTCACGGTCGTCGGCGGCTTCCTCGGAGCCGGCAAGACGAC
GCTGCTGAACCGGCTGCTCGCCGGCTCGCAGGGCCGCTACGCGGTGCTGGTCAACGATTTCGGGGCGATCAACGTCGATG
CGGGCCTGATCCGGGACCATGACGGCCAGACCCTGCGGCTGACCAATGGCTGCGTCTGCTGCAGCCTCGCCGACGGCTTC
CTCGACACGCTGATGCGCGTCCTCGCGGAGCCCGAGCCCTTCGACCACATCGTCATTGAGGCGAGCGGCGTCGGCGATCC
GGGCGCCATCGCGGAGATCGCCCTGGTGGAGCCAGGCCTCGTCCTGCGCGGCGTCGTCGTGCTGGCGGATGCCGAGCGCC
TGCCCGGCCTCGCCGCCGACCCGCGCCTGGGCGACACGCTCGCCCGCCAGATCCGCGCCGCCGACCTCCTCGTGCTCAAC
AAGCGCGACCTCGTGGACGCGTCCGGCCGCGCGGCCGCCCGGGACACGCTCGCCGCCCTCGCGCCGGGCGTCCCGGTGGT
CGAGACCGTGGCGGCCGCGCTGCCCGCGGCGGTCTTCGATCTCAGCGGCGCGGGTCCGGAGCGGGTCCGGCCGGGATCGA
GCGGGCTGCGGGCCGAGGCGGTCCCGCACGAGGAGATCTTCCAGCGCCTGCTCTACCGGCGCGCGGGCGCGTTCGACCGC
GTCGGGCTCGAGCGCGCGCTCGCCGGTATGCCGGCCTCGCTCCTGCGGCTGAAGGGGCGCCTCGGTCTGGCCGGCCGATC
CGAGACGCATCTGCTTCAGATGGTCGGGCGCCGCTGGAGCCTGTCGCCGCTGCCGGAGCCCGCGCCGGACGGGGCCGAGC
TCGTCGGCATCGCGGCGACCGATCCCGAAGCCGGCCCGGCGCTGGCCGGCCTCCTCGACGCCGCGCTGCGACCCCCGCAA
ACCCCACACGGAGACCGAACCCGATGCGCCTGA

Upstream 100 bases:

>100_bases
TGCTCGACGCGGACCCGTACGAAGTGCCCCCGGAGGCGCTCAAGGACGTCCCGGTCCACGCCACGGTGCTCGGCGGCCGC
GTCTTCGCGGTGCCGCCGGC

Downstream 100 bases:

>100_bases
CCAAACGCACGCTCCTCGGCGCCGGCCTCTCGGTCCTCGCCGCGCCCCTGACGGCCCCGATCCTCGACCTGCCGAAGGCG
CTGGCCGACGACGCGATCGC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRRGLPAPATRCPLTVVGGFLGAGKTTLLNRLLAGSQGRYAVLVNDFGAINVDAGLIRDHDGQTLRLTNGCVCCSLADGF
LDTLMRVLAEPEPFDHIVIEASGVGDPGAIAEIALVEPGLVLRGVVVLADAERLPGLAADPRLGDTLARQIRAADLLVLN
KRDLVDASGRAAARDTLAALAPGVPVVETVAAALPAAVFDLSGAGPERVRPGSSGLRAEAVPHEEIFQRLLYRRAGAFDR
VGLERALAGMPASLLRLKGRLGLAGRSETHLLQMVGRRWSLSPLPEPAPDGAELVGIAATDPEAGPALAGLLDAALRPPQ
TPHGDRTRCA

Sequences:

>Translated_330_residues
MRRGLPAPATRCPLTVVGGFLGAGKTTLLNRLLAGSQGRYAVLVNDFGAINVDAGLIRDHDGQTLRLTNGCVCCSLADGF
LDTLMRVLAEPEPFDHIVIEASGVGDPGAIAEIALVEPGLVLRGVVVLADAERLPGLAADPRLGDTLARQIRAADLLVLN
KRDLVDASGRAAARDTLAALAPGVPVVETVAAALPAAVFDLSGAGPERVRPGSSGLRAEAVPHEEIFQRLLYRRAGAFDR
VGLERALAGMPASLLRLKGRLGLAGRSETHLLQMVGRRWSLSPLPEPAPDGAELVGIAATDPEAGPALAGLLDAALRPPQ
TPHGDRTRCA
>Mature_330_residues
MRRGLPAPATRCPLTVVGGFLGAGKTTLLNRLLAGSQGRYAVLVNDFGAINVDAGLIRDHDGQTLRLTNGCVCCSLADGF
LDTLMRVLAEPEPFDHIVIEASGVGDPGAIAEIALVEPGLVLRGVVVLADAERLPGLAADPRLGDTLARQIRAADLLVLN
KRDLVDASGRAAARDTLAALAPGVPVVETVAAALPAAVFDLSGAGPERVRPGSSGLRAEAVPHEEIFQRLLYRRAGAFDR
VGLERALAGMPASLLRLKGRLGLAGRSETHLLQMVGRRWSLSPLPEPAPDGAELVGIAATDPEAGPALAGLLDAALRPPQ
TPHGDRTRCA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI223941779, Length=306, Percent_Identity=27.7777777777778, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI33469141, Length=320, Percent_Identity=27.8125, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI126722884, Length=320, Percent_Identity=27.5, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI148727351, Length=320, Percent_Identity=27.1875, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI146231952, Length=320, Percent_Identity=27.5, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223941776, Length=309, Percent_Identity=27.1844660194175, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI119120938, Length=294, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI87082430, Length=319, Percent_Identity=31.3479623824451, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788499, Length=161, Percent_Identity=33.5403726708075, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=185, Percent_Identity=30.2702702702703, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 34283; Mature: 34283

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGLPAPATRCPLTVVGGFLGAGKTTLLNRLLAGSQGRYAVLVNDFGAINVDAGLIRDH
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCEEECCCCEEECC
DGQTLRLTNGCVCCSLADGFLDTLMRVLAEPEPFDHIVIEASGVGDPGAIAEIALVEPGL
CCCEEEEECCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHEEEEEECCCH
VLRGVVVLADAERLPGLAADPRLGDTLARQIRAADLLVLNKRDLVDASGRAAARDTLAAL
HHHHEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHH
APGVPVVETVAAALPAAVFDLSGAGPERVRPGSSGLRAEAVPHEEIFQRLLYRRAGAFDR
CCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
VGLERALAGMPASLLRLKGRLGLAGRSETHLLQMVGRRWSLSPLPEPAPDGAELVGIAAT
HHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEC
DPEAGPALAGLLDAALRPPQTPHGDRTRCA
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRGLPAPATRCPLTVVGGFLGAGKTTLLNRLLAGSQGRYAVLVNDFGAINVDAGLIRDH
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCEEECCCCEEECC
DGQTLRLTNGCVCCSLADGFLDTLMRVLAEPEPFDHIVIEASGVGDPGAIAEIALVEPGL
CCCEEEEECCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHEEEEEECCCH
VLRGVVVLADAERLPGLAADPRLGDTLARQIRAADLLVLNKRDLVDASGRAAARDTLAAL
HHHHEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHH
APGVPVVETVAAALPAAVFDLSGAGPERVRPGSSGLRAEAVPHEEIFQRLLYRRAGAFDR
CCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
VGLERALAGMPASLLRLKGRLGLAGRSETHLLQMVGRRWSLSPLPEPAPDGAELVGIAAT
HHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEC
DPEAGPALAGLLDAALRPPQTPHGDRTRCA
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]