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The map label for this gene is hbpA [H]

Identifier: 170751148

GI number: 170751148

Start: 5077162

End: 5078781

Strand: Reverse

Name: hbpA [H]

Synonym: Mrad2831_4764

Alternate gene names: 170751148

Gene position: 5078781-5077162 (Counterclockwise)

Preceding gene: 170751149

Following gene: 170751147

Centisome position: 83.56

GC content: 67.78

Gene sequence:

>1620_bases
ATGCGCCTGACCAAACGCACGCTCCTCGGCGCCGGCCTCTCGGTCCTCGCCGCGCCCCTGACGGCCCCGATCCTCGACCT
GCCGAAGGCGCTGGCCGACGACGCGATCGCGCCGCTGGTGATCGGCACCAACCAAGTGCCGCGCCACTTCAACGGCGCCG
TGCAGTCCGGCATCGCCACCGGGATGGTCTCGACGCAGATCTTCGCGAGCCCGCTGCGCTACGACGATCAGTGGAACCCG
CAACCCTATCTGGCGAAATCCTGGACTATCGCCCCCGACAACTTGAGCGTGACGCTCCACCTCGTAGAGGACGCCGTCTT
CCACGACGGGCACCCGCTCACCGCGGAGGATGTCGCCTTCTCGATCGGGGTGATCAAGGCCAACCATCCGTTCCAGACCA
TGCTGGAGCCGGTCTCGACGGTCGAGACCCCCGACGCCCACACGGTCATCATCCGGCTCGCGCGCCCGCACCCGGCGCTG
CTGCTGGCCATGTCGCCCGGCCTGATGCCGATCCTGCCCAAGCACGTCTACGGCGACGGCCAGGACATCAAGACCCATCC
GGCCAACCTGAAGCCCGTCGGATCGGGGCCGTTCAAGTTCGTCGAGTACAAGCAGGGCGAGTCGATCCAGCTCGAGCGGT
TCGACCGGTTCTTCATCCCCGGGCGGCCCAAGCTGGCGCGGCTCGTCTACCGGATCCTGCCGGACCAGAACAGCCTCGTC
ATCGCCACCGAGCGGCGCGAGATCGGCATGCTGCCGTTCCTGTCCTCGGTGCGGGACATCGAGCGCCTCGCCAAGGCGCC
GACCCTGACGGTGACGGATCGCGGCTTCGAGGGGATCGGCCCGATCAACTGGCTGGCCTTCAACTGCGGGAAGAAGCCCC
TCGACGACGTGCGCGTCCGTCGGGCCATCGCGCTGGCGGCCAACCGCGCTTTCATCACCGGCAAGCTGCTCGGCGGCGTG
GCGAAACCCGCCACCGGCCCGATCGTGCCGGGCTCGCCGTTCTACGAGCCGGCCGTCGACCTCTACACGCTCGACATCGC
CAAGGCGGACGCCCTGCTCGACGAGGCCGGGCTGAAGAAGGGGCCGGACGGCACGCGGTTCCCGCTCACCATCGACTACA
TCCCCAACGACAACGACCAGCAGCGCAACGTCGCCGAGTACCTGCGGGCCGGCCTCAAGCGGATCGGCATCGCCCTTCAG
GTCCGGGCCGCGCCGGACTTCCCGACCTGGGCGCAGCGCGTCTCCAACTTCGACTTCGACCTGACCATGGACAACGTCTT
CAACTGGGGCGACCCGGTGATCGGCGTGGCGCGGACCTACCTGTCGACCAACATCCGCAAGGGCGTCATCTGGTCGAACA
CGCAGCAGTACAAGAATCCGAAGGTCGACGAGCTGCTAAACGCCGCCGCGGTCGAGACCGACCTGGAGAAGCGCAAGGCG
CTCTACAGCGAATTCCAGAAGATCGTCGTGTCCGAGGCGCCGATCGCCTATATCAACCTCACCCCCTACAAGGCGGTCTA
CGACAAGCGCCTGACGAACCTGCCCCTGTCGATCTGGGGGCCGCTCTCGCCCCTCGACGAGGTCGCCTGGGCGCAGGGCG
CCGCCGGAGCCGAGCGATGA

Upstream 100 bases:

>100_bases
TCGGCATCGCGGCGACCGATCCCGAAGCCGGCCCGGCGCTGGCCGGCCTCCTCGACGCCGCGCTGCGACCCCCGCAAACC
CCACACGGAGACCGAACCCG

Downstream 100 bases:

>100_bases
CGGGCCTGCGCAGGCTCGGCGCGACGGCGGCGAACGCCGCCGGCCTGCTGCTCGCCGTGGTGGTGCTGAACTTCCTGCTG
ATCCAGGCGGCGCCGGGCGA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MRLTKRTLLGAGLSVLAAPLTAPILDLPKALADDAIAPLVIGTNQVPRHFNGAVQSGIATGMVSTQIFASPLRYDDQWNP
QPYLAKSWTIAPDNLSVTLHLVEDAVFHDGHPLTAEDVAFSIGVIKANHPFQTMLEPVSTVETPDAHTVIIRLARPHPAL
LLAMSPGLMPILPKHVYGDGQDIKTHPANLKPVGSGPFKFVEYKQGESIQLERFDRFFIPGRPKLARLVYRILPDQNSLV
IATERREIGMLPFLSSVRDIERLAKAPTLTVTDRGFEGIGPINWLAFNCGKKPLDDVRVRRAIALAANRAFITGKLLGGV
AKPATGPIVPGSPFYEPAVDLYTLDIAKADALLDEAGLKKGPDGTRFPLTIDYIPNDNDQQRNVAEYLRAGLKRIGIALQ
VRAAPDFPTWAQRVSNFDFDLTMDNVFNWGDPVIGVARTYLSTNIRKGVIWSNTQQYKNPKVDELLNAAAVETDLEKRKA
LYSEFQKIVVSEAPIAYINLTPYKAVYDKRLTNLPLSIWGPLSPLDEVAWAQGAAGAER

Sequences:

>Translated_539_residues
MRLTKRTLLGAGLSVLAAPLTAPILDLPKALADDAIAPLVIGTNQVPRHFNGAVQSGIATGMVSTQIFASPLRYDDQWNP
QPYLAKSWTIAPDNLSVTLHLVEDAVFHDGHPLTAEDVAFSIGVIKANHPFQTMLEPVSTVETPDAHTVIIRLARPHPAL
LLAMSPGLMPILPKHVYGDGQDIKTHPANLKPVGSGPFKFVEYKQGESIQLERFDRFFIPGRPKLARLVYRILPDQNSLV
IATERREIGMLPFLSSVRDIERLAKAPTLTVTDRGFEGIGPINWLAFNCGKKPLDDVRVRRAIALAANRAFITGKLLGGV
AKPATGPIVPGSPFYEPAVDLYTLDIAKADALLDEAGLKKGPDGTRFPLTIDYIPNDNDQQRNVAEYLRAGLKRIGIALQ
VRAAPDFPTWAQRVSNFDFDLTMDNVFNWGDPVIGVARTYLSTNIRKGVIWSNTQQYKNPKVDELLNAAAVETDLEKRKA
LYSEFQKIVVSEAPIAYINLTPYKAVYDKRLTNLPLSIWGPLSPLDEVAWAQGAAGAER
>Mature_539_residues
MRLTKRTLLGAGLSVLAAPLTAPILDLPKALADDAIAPLVIGTNQVPRHFNGAVQSGIATGMVSTQIFASPLRYDDQWNP
QPYLAKSWTIAPDNLSVTLHLVEDAVFHDGHPLTAEDVAFSIGVIKANHPFQTMLEPVSTVETPDAHTVIIRLARPHPAL
LLAMSPGLMPILPKHVYGDGQDIKTHPANLKPVGSGPFKFVEYKQGESIQLERFDRFFIPGRPKLARLVYRILPDQNSLV
IATERREIGMLPFLSSVRDIERLAKAPTLTVTDRGFEGIGPINWLAFNCGKKPLDDVRVRRAIALAANRAFITGKLLGGV
AKPATGPIVPGSPFYEPAVDLYTLDIAKADALLDEAGLKKGPDGTRFPLTIDYIPNDNDQQRNVAEYLRAGLKRIGIALQ
VRAAPDFPTWAQRVSNFDFDLTMDNVFNWGDPVIGVARTYLSTNIRKGVIWSNTQQYKNPKVDELLNAAAVETDLEKRKA
LYSEFQKIVVSEAPIAYINLTPYKAVYDKRLTNLPLSIWGPLSPLDEVAWAQGAAGAER

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=26.3358778625954, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787762, Length=446, Percent_Identity=26.2331838565022, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787052, Length=449, Percent_Identity=25.1670378619154, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787495, Length=538, Percent_Identity=25.2788104089219, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787551, Length=528, Percent_Identity=24.2424242424242, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789397, Length=543, Percent_Identity=26.5193370165746, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789887, Length=494, Percent_Identity=23.6842105263158, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082063, Length=393, Percent_Identity=25.4452926208651, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59162; Mature: 59162

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTKRTLLGAGLSVLAAPLTAPILDLPKALADDAIAPLVIGTNQVPRHFNGAVQSGIAT
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHH
GMVSTQIFASPLRYDDQWNPQPYLAKSWTIAPDNLSVTLHLVEDAVFHDGHPLTAEDVAF
HHHHHHHHHHCCCCCCCCCCCCCEECEEEECCCCCEEEEEEEEHHHHCCCCCCCHHHHEE
SIGVIKANHPFQTMLEPVSTVETPDAHTVIIRLARPHPALLLAMSPGLMPILPKHVYGDG
EEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHCCCC
QDIKTHPANLKPVGSGPFKFVEYKQGESIQLERFDRFFIPGRPKLARLVYRILPDQNSLV
CCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCEECCCCCHHHHHHHHHHCCCCCCEE
IATERREIGMLPFLSSVRDIERLAKAPTLTVTDRGFEGIGPINWLAFNCGKKPLDDVRVR
EEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHH
RAIALAANRAFITGKLLGGVAKPATGPIVPGSPFYEPAVDLYTLDIAKADALLDEAGLKK
HHHHHHHCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCC
GPDGTRFPLTIDYIPNDNDQQRNVAEYLRAGLKRIGIALQVRAAPDFPTWAQRVSNFDFD
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHCCCCCE
LTMDNVFNWGDPVIGVARTYLSTNIRKGVIWSNTQQYKNPKVDELLNAAAVETDLEKRKA
EEHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHH
LYSEFQKIVVSEAPIAYINLTPYKAVYDKRLTNLPLSIWGPLSPLDEVAWAQGAAGAER
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLTKRTLLGAGLSVLAAPLTAPILDLPKALADDAIAPLVIGTNQVPRHFNGAVQSGIAT
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHH
GMVSTQIFASPLRYDDQWNPQPYLAKSWTIAPDNLSVTLHLVEDAVFHDGHPLTAEDVAF
HHHHHHHHHHCCCCCCCCCCCCCEECEEEECCCCCEEEEEEEEHHHHCCCCCCCHHHHEE
SIGVIKANHPFQTMLEPVSTVETPDAHTVIIRLARPHPALLLAMSPGLMPILPKHVYGDG
EEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHCCCC
QDIKTHPANLKPVGSGPFKFVEYKQGESIQLERFDRFFIPGRPKLARLVYRILPDQNSLV
CCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCEECCCCCHHHHHHHHHHCCCCCCEE
IATERREIGMLPFLSSVRDIERLAKAPTLTVTDRGFEGIGPINWLAFNCGKKPLDDVRVR
EEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHH
RAIALAANRAFITGKLLGGVAKPATGPIVPGSPFYEPAVDLYTLDIAKADALLDEAGLKK
HHHHHHHCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCC
GPDGTRFPLTIDYIPNDNDQQRNVAEYLRAGLKRIGIALQVRAAPDFPTWAQRVSNFDFD
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHCCCCCE
LTMDNVFNWGDPVIGVARTYLSTNIRKGVIWSNTQQYKNPKVDELLNAAAVETDLEKRKA
EEHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHH
LYSEFQKIVVSEAPIAYINLTPYKAVYDKRLTNLPLSIWGPLSPLDEVAWAQGAAGAER
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]