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The map label for this gene is yodT [H]

Identifier: 170751121

GI number: 170751121

Start: 5043652

End: 5044983

Strand: Direct

Name: yodT [H]

Synonym: Mrad2831_4737

Alternate gene names: 170751121

Gene position: 5043652-5044983 (Clockwise)

Preceding gene: 170751120

Following gene: 170751122

Centisome position: 82.98

GC content: 69.29

Gene sequence:

>1332_bases
ATGACCCGCATCCTGCACCGCCAGATCAACGCGAACCTGCGCATCGCCTCGGGTGGCAAGGGCGTCGAACTCTTCGACCG
GGATGGACGCAGCTACATCGACGCCTCGGGCGGCGCGGCGGTGTCCTGCCTCGGGCACGGGCATCCGGACGTCATCGCGG
CGCTTCATGCCCAGGCCGACAAGCTAGCCTACGCCCACACCAGCTTCTTCACCACCGAGGTGGCCGAAGCCTTGGCTGAC
CGCCTCATCGCCGATGCACCGGCCGGCTTGGACTACGTCTACTTTGTCTCGGGCGGCTCAGAGGCCGTCGAGGCCGCGCT
CAAGATGGCGCGGCAATACTTCGTCGAGATCGGGCAGCCGCAGCGCTCCAAGATCATCGCTCGGCGACAGAGCTACCACG
GCAATACGCTCGGCGCGCTGGCTACCGGTGGCAACGAGTGGCGACGCGCGCAATTCAGGCCGCTGCTCGCTGAGACCCAT
CACATCGATCCCTGCTACGCCTACCGCTACCGGGAGGCCGGCGAGAGCGAGACCGAGTACGGCGCTCGGGCGGCGCAGGC
GCTGGAGGACAAGATCCTCGCACTCGGCCCCGATACCGTGATGGCCTTCGTGGCCGAGCCGGTCGTTGGGGCGACGGCCG
GCGCCGTTCCGGCGGTCCCCGGCTACTTCCGCCGCATCCGCGAGATCTGCGACCGGTACGGCGTACTGCTCCTCCTCGAC
GAGGTGATGTGCGGCATGGGTCGCACTGGAACGCTTCACGCCTGCGAGCAGGATGGCATCGCCCCGGACCTGCTGACAGT
CGCGAAGGGGCTTGGCGGCGGCTACCAGCCCATCGGCGCGACCTTCCTGTCGGGCAAGATCTACGAGGCCTTCGCCCAGG
GCTCGGGCCTGTTCCAGCACGGGCACACCTACATCTGCCACCCCATGGCCTGCGCGGCCGCGCTCGCCGTGCAGGAGGTG
ATCGCCCGCGATCGCCTCCTCGACAACGTCAAGGCGATGGGCACCCACCTGAGCCGCCGGCTCGGCGAGCGCTTCGGCAA
CCACCCGCATGTCGGCGACATCCGCGGACGCGGCCTGTTCATGGGCGTCGAGGTCGTCGAGGACCGCGGCACCCAGGCTC
CCTTCGATCCGGCCCTGAAGCTGCACGCGCGGATCAAGCGGGAGGCGATGAACCGCGGCCTGGCGGTCTACCCGGCCGGT
GGCACCCTCGACGGGGCCCGCGGCGACCACGTGCTGCTGGCGCCGCCCTTCATCATCGACACCGCGACTGTGGACACGGT
CGTCGAACGCCTTGGCGAAGCGGTCGATGCGGCCATCGCCCAAGCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGGGGCGGCGATGCCTCGCTCGCCGCGATCAAGCGCAGCGAGGCGCAGCTCACCGCCTTCGGCATCCACTGGTCACCC
CCGCCTGCAAGGAGATCGCA

Downstream 100 bases:

>100_bases
GAGCGGCATGCCCCAACGACCCGCCATGGGTGAGCTCTGACCCAACCGTAGGAAGCCTGACATGCGCATTCTGAAACACG
CGGCCATCGCCGCGACGATG

Product: hypothetical protein

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MTRILHRQINANLRIASGGKGVELFDRDGRSYIDASGGAAVSCLGHGHPDVIAALHAQADKLAYAHTSFFTTEVAEALAD
RLIADAPAGLDYVYFVSGGSEAVEAALKMARQYFVEIGQPQRSKIIARRQSYHGNTLGALATGGNEWRRAQFRPLLAETH
HIDPCYAYRYREAGESETEYGARAAQALEDKILALGPDTVMAFVAEPVVGATAGAVPAVPGYFRRIREICDRYGVLLLLD
EVMCGMGRTGTLHACEQDGIAPDLLTVAKGLGGGYQPIGATFLSGKIYEAFAQGSGLFQHGHTYICHPMACAAALAVQEV
IARDRLLDNVKAMGTHLSRRLGERFGNHPHVGDIRGRGLFMGVEVVEDRGTQAPFDPALKLHARIKREAMNRGLAVYPAG
GTLDGARGDHVLLAPPFIIDTATVDTVVERLGEAVDAAIAQAA

Sequences:

>Translated_443_residues
MTRILHRQINANLRIASGGKGVELFDRDGRSYIDASGGAAVSCLGHGHPDVIAALHAQADKLAYAHTSFFTTEVAEALAD
RLIADAPAGLDYVYFVSGGSEAVEAALKMARQYFVEIGQPQRSKIIARRQSYHGNTLGALATGGNEWRRAQFRPLLAETH
HIDPCYAYRYREAGESETEYGARAAQALEDKILALGPDTVMAFVAEPVVGATAGAVPAVPGYFRRIREICDRYGVLLLLD
EVMCGMGRTGTLHACEQDGIAPDLLTVAKGLGGGYQPIGATFLSGKIYEAFAQGSGLFQHGHTYICHPMACAAALAVQEV
IARDRLLDNVKAMGTHLSRRLGERFGNHPHVGDIRGRGLFMGVEVVEDRGTQAPFDPALKLHARIKREAMNRGLAVYPAG
GTLDGARGDHVLLAPPFIIDTATVDTVVERLGEAVDAAIAQAA
>Mature_442_residues
TRILHRQINANLRIASGGKGVELFDRDGRSYIDASGGAAVSCLGHGHPDVIAALHAQADKLAYAHTSFFTTEVAEALADR
LIADAPAGLDYVYFVSGGSEAVEAALKMARQYFVEIGQPQRSKIIARRQSYHGNTLGALATGGNEWRRAQFRPLLAETHH
IDPCYAYRYREAGESETEYGARAAQALEDKILALGPDTVMAFVAEPVVGATAGAVPAVPGYFRRIREICDRYGVLLLLDE
VMCGMGRTGTLHACEQDGIAPDLLTVAKGLGGGYQPIGATFLSGKIYEAFAQGSGLFQHGHTYICHPMACAAALAVQEVI
ARDRLLDNVKAMGTHLSRRLGERFGNHPHVGDIRGRGLFMGVEVVEDRGTQAPFDPALKLHARIKREAMNRGLAVYPAGG
TLDGARGDHVLLAPPFIIDTATVDTVVERLGEAVDAAIAQAA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=421, Percent_Identity=28.2660332541568, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=358, Percent_Identity=29.8882681564246, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=28.7981859410431, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI226442709, Length=338, Percent_Identity=29.8816568047337, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI226442705, Length=358, Percent_Identity=29.0502793296089, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=27.1867612293144, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI284507298, Length=342, Percent_Identity=27.7777777777778, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI188536080, Length=390, Percent_Identity=22.8205128205128, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI38679950, Length=390, Percent_Identity=22.8205128205128, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI38679946, Length=390, Percent_Identity=22.8205128205128, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788044, Length=426, Percent_Identity=33.8028169014084, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789759, Length=421, Percent_Identity=33.0166270783848, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI145693181, Length=349, Percent_Identity=33.810888252149, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1789016, Length=429, Percent_Identity=32.8671328671329, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786991, Length=429, Percent_Identity=30.0699300699301, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787560, Length=423, Percent_Identity=29.7872340425532, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786349, Length=323, Percent_Identity=27.8637770897833, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32564660, Length=446, Percent_Identity=29.5964125560538, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25144271, Length=413, Percent_Identity=25.6658595641646, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=26.9141531322506, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=250, Percent_Identity=29.2, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324432, Length=358, Percent_Identity=31.2849162011173, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=428, Percent_Identity=26.6355140186916, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324386, Length=444, Percent_Identity=25, Blast_Score=125, Evalue=9e-30,
Organism=Drosophila melanogaster, GI21357415, Length=408, Percent_Identity=29.9019607843137, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI161085790, Length=443, Percent_Identity=29.1196388261851, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI28574759, Length=442, Percent_Identity=29.185520361991, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356575, Length=436, Percent_Identity=28.4403669724771, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281366494, Length=393, Percent_Identity=25.9541984732824, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667139, Length=393, Percent_Identity=25.9541984732824, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667143, Length=393, Percent_Identity=25.9541984732824, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 47397; Mature: 47265

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRILHRQINANLRIASGGKGVELFDRDGRSYIDASGGAAVSCLGHGHPDVIAALHAQAD
CCCHHHHHCCCCEEEECCCCCCEEEECCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHH
KLAYAHTSFFTTEVAEALADRLIADAPAGLDYVYFVSGGSEAVEAALKMARQYFVEIGQP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
QRSKIIARRQSYHGNTLGALATGGNEWRRAQFRPLLAETHHIDPCYAYRYREAGESETEY
HHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
GARAAQALEDKILALGPDTVMAFVAEPVVGATAGAVPAVPGYFRRIREICDRYGVLLLLD
HHHHHHHHHHHHEEECHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EVMCGMGRTGTLHACEQDGIAPDLLTVAKGLGGGYQPIGATFLSGKIYEAFAQGSGLFQH
HHHHCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHCCCCCHHC
GHTYICHPMACAAALAVQEVIARDRLLDNVKAMGTHLSRRLGERFGNHPHVGDIRGRGLF
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
MGVEVVEDRGTQAPFDPALKLHARIKREAMNRGLAVYPAGGTLDGARGDHVLLAPPFIID
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEE
TATVDTVVERLGEAVDAAIAQAA
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRILHRQINANLRIASGGKGVELFDRDGRSYIDASGGAAVSCLGHGHPDVIAALHAQAD
CCHHHHHCCCCEEEECCCCCCEEEECCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHH
KLAYAHTSFFTTEVAEALADRLIADAPAGLDYVYFVSGGSEAVEAALKMARQYFVEIGQP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
QRSKIIARRQSYHGNTLGALATGGNEWRRAQFRPLLAETHHIDPCYAYRYREAGESETEY
HHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
GARAAQALEDKILALGPDTVMAFVAEPVVGATAGAVPAVPGYFRRIREICDRYGVLLLLD
HHHHHHHHHHHHEEECHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EVMCGMGRTGTLHACEQDGIAPDLLTVAKGLGGGYQPIGATFLSGKIYEAFAQGSGLFQH
HHHHCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHCCCCCHHC
GHTYICHPMACAAALAVQEVIARDRLLDNVKAMGTHLSRRLGERFGNHPHVGDIRGRGLF
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
MGVEVVEDRGTQAPFDPALKLHARIKREAMNRGLAVYPAGGTLDGARGDHVLLAPPFIID
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEE
TATVDTVVERLGEAVDAAIAQAA
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]