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The map label for this gene is actP [H]

Identifier: 170751105

GI number: 170751105

Start: 5024441

End: 5025832

Strand: Direct

Name: actP [H]

Synonym: Mrad2831_4721

Alternate gene names: 170751105

Gene position: 5024441-5025832 (Clockwise)

Preceding gene: 170751104

Following gene: 170751106

Centisome position: 82.67

GC content: 64.44

Gene sequence:

>1392_bases
ATGCAGCCAAACTGGATCGTTCTCTCCCTGACCCTGGCCTACATGGCGGCGATGGGGCTGATCAGTTTCTCTGTGCGACG
CCATGCGAGGAGCGCTGGAAGCTTTACCTCCGGCGGCACGCGCTATCCGGCGTTCCTGATCGGCTTTCTGCTGATGTCGG
AATTCATCGGGACCGCCACGAGCGTCGGCACGACACAGACGGCCTACAGGGTCGGCGTGTCGGCCGCCTGGAACGTCCTC
GCCCTCGCCGTCGGTTTCGTTCTCTACGCCATTCTCCTGGCGCCCCGCTTCAAGGAACTCGGCGAGAACACGATCTCCGG
GGCGTTGGCCAAGGCCTACGGTCGCCCGACCAAGCTCGCGACCTCGGTCATCATGATCTTCGCGCTCCAGATCGTCGCGG
TCTCGACCTATGCGGGCGGCGGTACGATCCTGGCGGGCCTCCTCAACGTCGACCGGACCAGCGCCATCGTCATCACGGGT
ATCGTAGCGACGCTTTATGTCAGTGTCGGGGGGATGCGCTCGGTTATCTATACGAACGTCCTGCATGCCGTCGTGAAGTA
TCTTGGCATCCTCGCGGCCGTGGCCTTCGGATTGTCTCAGGTCGGCGGCTTCGACAACCTGCGGGCCCACGTGCCCGAAG
CGATGTTCGCGGTCGATACGGTCGGCTGGTCACAGATCTTCGCGTGGATGGTCGCCGGCATCGGCGCGGTCTTCTCGACG
CAATACGTGATCCAGGCCATCAATACCGTGCAGGACGGGCGCACGGCGCGGCAGGCCAGCTTTTATTGTGCCTTCCTGCT
CGTGCCGTTCGGCATCGGCGCTGCCCTGGTCGGTGTCTGCGCGGCGGCGCTGCTGCCGGGAATCCCCGCGATCCAGGCTT
TGCCGGGCCTGATCGCCCGGATGGACGATCTTTTGGCCGCCATCGTGGTGGCGGGATTGGCGGGATCGCTGTTCGGCACG
ATCTCGGCCCTTAGCATCGGCGCTGCCACCCTACTGTTCAAGGATTTCTATCATCCCCGCCGTCGGAGCGAGGATGGGAC
GTCGTCCCTGCGGTTCGTCCGCAGCATGACGGTGCTCGTGGGCCTGATCCCGATTCCCCTGGCGATCTTCGCGCCGGATA
TCCTGAAGGTGACGTTCCTCGCGAAATCCCTGCGGGCGACCCTGGCGGTCTTGGTCATCTTTGCCTTCTACGCTCCGCGC
TTCGGCACACCGCGGGCCGCCGTCGTCAGCATCCTGGTTTCCCTCGTCCTGACGATCGGCTGGTTCCTCGCCGGCGATCC
CGGGGGAATCGACAACGCCTATGTGGCCCTCGTCATTCCCCTAGCGGTGATGGGTACAGCCGAACTCCGGAAGAGGACCA
CGCTCCGGAACGAACAGGTTGCGGCGCCCTGA

Upstream 100 bases:

>100_bases
CGTTCGTGCGAGGAAAGCTGCGGCCTCGAATGATTTCGGAGGAAACATGCTGGGGTCCCTTGGCGCCCAGGCACTACGGC
GTCGCCGTTAGGCCGCACCC

Downstream 100 bases:

>100_bases
CGGGACGGGTGTCCCGGCGGCGATCTAGCTGCCCCCCGCGGACCATGCTAAATAGTGCAGATGTCCGAGGCTCTTGAGAT
CGCCCATGGCGCCTTCGGCC

Product: Na+/solute symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MQPNWIVLSLTLAYMAAMGLISFSVRRHARSAGSFTSGGTRYPAFLIGFLLMSEFIGTATSVGTTQTAYRVGVSAAWNVL
ALAVGFVLYAILLAPRFKELGENTISGALAKAYGRPTKLATSVIMIFALQIVAVSTYAGGGTILAGLLNVDRTSAIVITG
IVATLYVSVGGMRSVIYTNVLHAVVKYLGILAAVAFGLSQVGGFDNLRAHVPEAMFAVDTVGWSQIFAWMVAGIGAVFST
QYVIQAINTVQDGRTARQASFYCAFLLVPFGIGAALVGVCAAALLPGIPAIQALPGLIARMDDLLAAIVVAGLAGSLFGT
ISALSIGAATLLFKDFYHPRRRSEDGTSSLRFVRSMTVLVGLIPIPLAIFAPDILKVTFLAKSLRATLAVLVIFAFYAPR
FGTPRAAVVSILVSLVLTIGWFLAGDPGGIDNAYVALVIPLAVMGTAELRKRTTLRNEQVAAP

Sequences:

>Translated_463_residues
MQPNWIVLSLTLAYMAAMGLISFSVRRHARSAGSFTSGGTRYPAFLIGFLLMSEFIGTATSVGTTQTAYRVGVSAAWNVL
ALAVGFVLYAILLAPRFKELGENTISGALAKAYGRPTKLATSVIMIFALQIVAVSTYAGGGTILAGLLNVDRTSAIVITG
IVATLYVSVGGMRSVIYTNVLHAVVKYLGILAAVAFGLSQVGGFDNLRAHVPEAMFAVDTVGWSQIFAWMVAGIGAVFST
QYVIQAINTVQDGRTARQASFYCAFLLVPFGIGAALVGVCAAALLPGIPAIQALPGLIARMDDLLAAIVVAGLAGSLFGT
ISALSIGAATLLFKDFYHPRRRSEDGTSSLRFVRSMTVLVGLIPIPLAIFAPDILKVTFLAKSLRATLAVLVIFAFYAPR
FGTPRAAVVSILVSLVLTIGWFLAGDPGGIDNAYVALVIPLAVMGTAELRKRTTLRNEQVAAP
>Mature_463_residues
MQPNWIVLSLTLAYMAAMGLISFSVRRHARSAGSFTSGGTRYPAFLIGFLLMSEFIGTATSVGTTQTAYRVGVSAAWNVL
ALAVGFVLYAILLAPRFKELGENTISGALAKAYGRPTKLATSVIMIFALQIVAVSTYAGGGTILAGLLNVDRTSAIVITG
IVATLYVSVGGMRSVIYTNVLHAVVKYLGILAAVAFGLSQVGGFDNLRAHVPEAMFAVDTVGWSQIFAWMVAGIGAVFST
QYVIQAINTVQDGRTARQASFYCAFLLVPFGIGAALVGVCAAALLPGIPAIQALPGLIARMDDLLAAIVVAGLAGSLFGT
ISALSIGAATLLFKDFYHPRRRSEDGTSSLRFVRSMTVLVGLIPIPLAIFAPDILKVTFLAKSLRATLAVLVIFAFYAPR
FGTPRAAVVSILVSLVLTIGWFLAGDPGGIDNAYVALVIPLAVMGTAELRKRTTLRNEQVAAP

Specific function: Transports acetate [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=364, Percent_Identity=27.7472527472527, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790503, Length=401, Percent_Identity=21.4463840399002, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 48618; Mature: 48618

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPNWIVLSLTLAYMAAMGLISFSVRRHARSAGSFTSGGTRYPAFLIGFLLMSEFIGTAT
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVGTTQTAYRVGVSAAWNVLALAVGFVLYAILLAPRFKELGENTISGALAKAYGRPTKLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
TSVIMIFALQIVAVSTYAGGGTILAGLLNVDRTSAIVITGIVATLYVSVGGMRSVIYTNV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LHAVVKYLGILAAVAFGLSQVGGFDNLRAHVPEAMFAVDTVGWSQIFAWMVAGIGAVFST
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QYVIQAINTVQDGRTARQASFYCAFLLVPFGIGAALVGVCAAALLPGIPAIQALPGLIAR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MDDLLAAIVVAGLAGSLFGTISALSIGAATLLFKDFYHPRRRSEDGTSSLRFVRSMTVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHH
GLIPIPLAIFAPDILKVTFLAKSLRATLAVLVIFAFYAPRFGTPRAAVVSILVSLVLTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
WFLAGDPGGIDNAYVALVIPLAVMGTAELRKRTTLRNEQVAAP
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQPNWIVLSLTLAYMAAMGLISFSVRRHARSAGSFTSGGTRYPAFLIGFLLMSEFIGTAT
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVGTTQTAYRVGVSAAWNVLALAVGFVLYAILLAPRFKELGENTISGALAKAYGRPTKLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
TSVIMIFALQIVAVSTYAGGGTILAGLLNVDRTSAIVITGIVATLYVSVGGMRSVIYTNV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LHAVVKYLGILAAVAFGLSQVGGFDNLRAHVPEAMFAVDTVGWSQIFAWMVAGIGAVFST
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QYVIQAINTVQDGRTARQASFYCAFLLVPFGIGAALVGVCAAALLPGIPAIQALPGLIAR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MDDLLAAIVVAGLAGSLFGTISALSIGAATLLFKDFYHPRRRSEDGTSSLRFVRSMTVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHH
GLIPIPLAIFAPDILKVTFLAKSLRATLAVLVIFAFYAPRFGTPRAAVVSILVSLVLTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
WFLAGDPGGIDNAYVALVIPLAVMGTAELRKRTTLRNEQVAAP
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA