| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is hmuV [H]
Identifier: 170750979
GI number: 170750979
Start: 4886289
End: 4887113
Strand: Direct
Name: hmuV [H]
Synonym: Mrad2831_4590
Alternate gene names: 170750979
Gene position: 4886289-4887113 (Clockwise)
Preceding gene: 170750978
Following gene: 170750980
Centisome position: 80.4
GC content: 78.55
Gene sequence:
>825_bases ATGCCTGATCCGGCCCTGCTCGTGGCCCGCGACCTGACCGTCACGGTGGCGGGGCGCGCGCTCGTGCGCGACGTCTCCCT GGCGGTGGAGGCCGGCAGCCTGCAGGTGATCGTCGGCCCGAACGGGGCCGGCAAGTCGACCCTCGTCGGCCTGCTCAGCG GCGCCCTGCGGCCCACGAGCGGCACCGTCGCCTATGACGGCGCGCCCGTGGCGACGATCCCGCCCTGGCGGCTCGCCGCG ATGCGGGCGGTGCTGCCGCAGGCGGCGCGCCTCGCCTTCCCGTTCGCGGCGGCCGAGGTCGCCCGGATCGGCCTGGACGG CATCGGCCGGGGCCTCGGGGCCCGCGACCGGGCGGCGATCCTGGCGCGGGCCCTCGCGCGGGCCGACGTGGCGCATCTCG CCGACCGGGCCTACCCGACCCTCTCGGGCGGGGAGCAGGCGCGGGTGCAGTTCGCCCGGGTGCTCTGTCAGCTGGAGGCC GGCCGCAAGGTCGCCGACCGGCAGGTGCTGTTCCTCGACGAGCCGACCGCGAGCCTCGACCTCCGGCACCAGGGCGCGCT GCTCGACGCCGCCGCCGGGCTGGCGGCGACCGGCGTCGCCGTGGTGGCGATCCTCCACGACCTCAACCTCGCGGCCGCCT ACGCCGACCGGCTGCTGGTCCTCGACGGCGGCCGGCTGCTCGCCGGCGGGCGGCCGGCCGAGGTCCTGACCGACGACCTG ATCGCCGGGGTCTTCGGCGTCCGCTGGCCGGTCGGGCGGGTGCCCGCGGGCGGCCAGCCCTTCCTGCTGCCGCACCGGGG TGCGGCCGGTCGCGTGCGGGACTGA
Upstream 100 bases:
>100_bases GGGATCGTCACCGCGCTGGTCGGCGCGCCGGTCTTCCTGTGGCTGCTCCTCGGCCGGGTGCGGGTGGACGATGTCTGACG ATGTCTGACGATGTCTGACC
Downstream 100 bases:
>100_bases TCGGACTTCGCGGCTCCCGGGCGGCGTCCGGCCCGCGCGGGCAGGCAATGCGCGGCGCGCGGGCCAGCAATCCCGGAAAT GTCGGTTGCACATCTCTGTC
Product: ABC transporter-like protein
Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 274; Mature: 273
Protein sequence:
>274_residues MPDPALLVARDLTVTVAGRALVRDVSLAVEAGSLQVIVGPNGAGKSTLVGLLSGALRPTSGTVAYDGAPVATIPPWRLAA MRAVLPQAARLAFPFAAAEVARIGLDGIGRGLGARDRAAILARALARADVAHLADRAYPTLSGGEQARVQFARVLCQLEA GRKVADRQVLFLDEPTASLDLRHQGALLDAAAGLAATGVAVVAILHDLNLAAAYADRLLVLDGGRLLAGGRPAEVLTDDL IAGVFGVRWPVGRVPAGGQPFLLPHRGAAGRVRD
Sequences:
>Translated_274_residues MPDPALLVARDLTVTVAGRALVRDVSLAVEAGSLQVIVGPNGAGKSTLVGLLSGALRPTSGTVAYDGAPVATIPPWRLAA MRAVLPQAARLAFPFAAAEVARIGLDGIGRGLGARDRAAILARALARADVAHLADRAYPTLSGGEQARVQFARVLCQLEA GRKVADRQVLFLDEPTASLDLRHQGALLDAAAGLAATGVAVVAILHDLNLAAAYADRLLVLDGGRLLAGGRPAEVLTDDL IAGVFGVRWPVGRVPAGGQPFLLPHRGAAGRVRD >Mature_273_residues PDPALLVARDLTVTVAGRALVRDVSLAVEAGSLQVIVGPNGAGKSTLVGLLSGALRPTSGTVAYDGAPVATIPPWRLAAM RAVLPQAARLAFPFAAAEVARIGLDGIGRGLGARDRAAILARALARADVAHLADRAYPTLSGGEQARVQFARVLCQLEAG RKVADRQVLFLDEPTASLDLRHQGALLDAAAGLAATGVAVVAILHDLNLAAAYADRLLVLDGGRLLAGGRPAEVLTDDLI AGVFGVRWPVGRVPAGGQPFLLPHRGAAGRVRD
Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]
COG id: COG4559
COG function: function code P; ABC-type hemin transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI171184400, Length=235, Percent_Identity=28.936170212766, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI9955963, Length=242, Percent_Identity=28.9256198347107, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI105990541, Length=219, Percent_Identity=27.8538812785388, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI42741659, Length=223, Percent_Identity=27.8026905829596, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI47078218, Length=213, Percent_Identity=29.1079812206573, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI45446740, Length=213, Percent_Identity=29.1079812206573, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1790739, Length=261, Percent_Identity=36.3984674329502, Blast_Score=144, Evalue=6e-36, Organism=Escherichia coli, GI1786345, Length=256, Percent_Identity=33.984375, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1786803, Length=264, Percent_Identity=31.8181818181818, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1788002, Length=224, Percent_Identity=36.6071428571429, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI87081791, Length=237, Percent_Identity=30.8016877637131, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787029, Length=228, Percent_Identity=33.7719298245614, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787712, Length=203, Percent_Identity=28.0788177339901, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789032, Length=224, Percent_Identity=31.6964285714286, Blast_Score=86, Evalue=4e-18, Organism=Escherichia coli, GI1789593, Length=243, Percent_Identity=28.8065843621399, Blast_Score=85, Evalue=7e-18, Organism=Escherichia coli, GI1790467, Length=234, Percent_Identity=32.4786324786325, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1789672, Length=240, Percent_Identity=25, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788761, Length=280, Percent_Identity=30, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87081709, Length=242, Percent_Identity=26.0330578512397, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=32.2274881516588, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786253, Length=215, Percent_Identity=33.953488372093, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1789864, Length=265, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=1e-16, Organism=Escherichia coli, GI48994997, Length=256, Percent_Identity=32.03125, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=29.4372294372294, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787792, Length=240, Percent_Identity=28.75, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789991, Length=253, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=29.2576419213974, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788225, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1790525, Length=242, Percent_Identity=28.099173553719, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789873, Length=220, Percent_Identity=30.4545454545455, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787370, Length=239, Percent_Identity=26.3598326359833, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1790534, Length=202, Percent_Identity=33.1683168316832, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1790190, Length=225, Percent_Identity=27.5555555555556, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI87081782, Length=243, Percent_Identity=27.1604938271605, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1786319, Length=212, Percent_Identity=27.8301886792453, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1786398, Length=225, Percent_Identity=27.1111111111111, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787105, Length=214, Percent_Identity=31.7757009345794, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786563, Length=225, Percent_Identity=28.4444444444444, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1788210, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787164, Length=214, Percent_Identity=30.3738317757009, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1786703, Length=215, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787112, Length=239, Percent_Identity=28.0334728033473, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI48995001, Length=233, Percent_Identity=26.1802575107296, Blast_Score=61, Evalue=1e-10, Organism=Caenorhabditis elegans, GI193209708, Length=236, Percent_Identity=30.5084745762712, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17541710, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17511077, Length=232, Percent_Identity=28.8793103448276, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71992290, Length=233, Percent_Identity=27.0386266094421, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115533608, Length=231, Percent_Identity=27.7056277056277, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17565938, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17543740, Length=227, Percent_Identity=27.7533039647577, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17558664, Length=228, Percent_Identity=25.8771929824561, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323959, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI24666092, Length=231, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21357907, Length=246, Percent_Identity=30.4878048780488, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI221512771, Length=212, Percent_Identity=25.4716981132075, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI24641565, Length=220, Percent_Identity=26.8181818181818, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR015863 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 28126; Mature: 27995
Theoretical pI: Translated: 10.48; Mature: 10.48
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 0.7 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.4 %Met (Mature Protein) 0.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPDPALLVARDLTVTVAGRALVRDVSLAVEAGSLQVIVGPNGAGKSTLVGLLSGALRPTS CCCCCEEEEECEEEEECCHHHHHHHHHEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCC GTVAYDGAPVATIPPWRLAAMRAVLPQAARLAFPFAAAEVARIGLDGIGRGLGARDRAAI CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCCCCCCHHHHH LARALARADVAHLADRAYPTLSGGEQARVQFARVLCQLEAGRKVADRQVLFLDEPTASLD HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEE LRHQGALLDAAAGLAATGVAVVAILHDLNLAAAYADRLLVLDGGRLLAGGRPAEVLTDDL ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCCCHHHHHHHH IAGVFGVRWPVGRVPAGGQPFLLPHRGAAGRVRD HHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCC >Mature Secondary Structure PDPALLVARDLTVTVAGRALVRDVSLAVEAGSLQVIVGPNGAGKSTLVGLLSGALRPTS CCCCEEEEECEEEEECCHHHHHHHHHEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCC GTVAYDGAPVATIPPWRLAAMRAVLPQAARLAFPFAAAEVARIGLDGIGRGLGARDRAAI CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCCCCCCHHHHH LARALARADVAHLADRAYPTLSGGEQARVQFARVLCQLEAGRKVADRQVLFLDEPTASLD HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEE LRHQGALLDAAAGLAATGVAVVAILHDLNLAAAYADRLLVLDGGRLLAGGRPAEVLTDDL ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCCCHHHHHHHH IAGVFGVRWPVGRVPAGGQPFLLPHRGAAGRVRD HHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]
Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 11743193; 11743194 [H]