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The map label for this gene is hxuC [H]

Identifier: 170750980

GI number: 170750980

Start: 4887199

End: 4889430

Strand: Direct

Name: hxuC [H]

Synonym: Mrad2831_4591

Alternate gene names: 170750980

Gene position: 4887199-4889430 (Clockwise)

Preceding gene: 170750979

Following gene: 170750983

Centisome position: 80.41

GC content: 74.19

Gene sequence:

>2232_bases
TTGCACATCTCTGTCGCGATCGGCGAGACAATCTTCAGCAAGCCAGCCATCCGCCAGCCAGCTCTCTGGAACGACTGTGT
GCGGGCGGCTGTCATCATGCCTTATGCTTCTCACCGGGCGCTCGTCGCCCTCGGCGTCGTGCTGGCGACCCTGCCGGGCG
CTCGGGCGGAGGAGGCCGGCCAGGCCGCGCTCCCCGAGCCCGCGATCGGCCTCGACACCCTGTCGGTCACCGCGACCAAG
ACCGCCATCCCGGCCGTCGACGCCCTGGCGGGCACGAGCGTCGTCCCGCGGGCCGCGCTCGACCGTCTCCAGCCCGGGCG
CCTGTCCGAGGTGCTGCGCGACGTGCCCGGCGTGATCACCCAGGAGAACCGGAACGACCCGGCGCAGGCGATCAACATCC
GCGGCCTCCAGGATTTCGGCCGGGTGAACGTCCTGGTCGACGGGGCCCGGCAGGATTTCCAGGTCTCGGGCCACGGGGCC
AACGGCGTGTTCTACCTCGATCCCGAGCTCGTCGGCGGCGTCGACGTCACCCGCGGGCCGACGGCGACGGTCTACGGCTC
CGGCGCCATCGGGGGCGTCGCGGCGTTCCGCACCCGGTCGATCGACGACATCCTGGCTCCCGACGAGAGCGCCGGCTTCG
TGCAGAAGCAGGGCTTCGGCACGAACGGCCAGCGCTTCGTGAACAGCTCGGCGCTCGGCGCCCGCATCGGCACCGCCGCG
GACGTGTTCGGGCAGTTCGTCTTCCGCGACACCGCGCCCTATCGCGACGGTGCCGGCCTGCCGGTGCCCGACACCGGCAG
CGAGCTGAACGCGGGCCTCGCCAAGCTCACCCTCCGGCCGGCCGAGGGGCACGCGCTCCACGCCACGGCGCTCCTGCAGC
GATTCGCCTTCGTCAACGGCGGCGATACCGGCGCGGGGGCCCGCTTCGCCAACGCCGTGCAGGCCGACACCGTCACCTTC
GGCTACCGATTCGCCCGACCGGACGTGCCGCTCGTCGACCTCAGCCTCGACGGCTACGCGACCACGACCCGCGACGCGCT
GACCTTCCTGCAGGACTCGCCGCGCGGTCTCTACGGCCGGCTCGGCACCCGGGCCGGCGACCGCCTGACCTACGACCTCG
CCACCGCGGGCTTCGACGCCCACAACACCGCCCGGTTCGAGACCGGCCCGGTCGCGCACGCGCTCACGCTCGGCGGCGAC
GGCGTGGCGAATCGCGTCCGGACCACCGACCAGGCCGGCGGCTTCGGCGCGGCCTTCACGCCGTCGGGACGGCGGGAGCT
GGCCGGCGCCTTCCTCCAGGACGAGATCCGCGCCGCGCCGTGGCTGCGCATCGTCGGCGCGCTCCGGCACGACGGCTACC
GGCTCGACGGCGGGGCCTATCGCGCGCGCGGCGCGCGGGTCTCGCCGAAGATCACGGTCGGCGTCGCGCCGGTCGGCGGC
CTCGAACTCTACGGGACCTATGCCGAGGGCTACCGCGCGCCCACGATCACCGAGACGCTGATGGAGGGCATCCACCCGTT
CCCGGCCTTCGCGATCCTGCCGAATCCGGCGCTGCGGCCGGAGGTGGCCCGCACCGTCGAGGGCGGCGCCAACCTGCGCG
CCGACGGGGTGGTGGGGCCGGAGGACGCGCTGCGGGCCAAGCTCGCGCTGTTCGACACGGCGGTCGACGGCTTCATCGAC
ATGCAGGCGGTCGGGCCGGCCTACTACGTCCCGGCGATTCCCGGCGTCCCGGCCTCGATCTGCGCCGCCCGGCCCGGGCG
CTTCCCCTGCGTGATCCCGGCCCGGTCCTACCAGTACCGGAACGTCGCCCGGGCCGACCTGTCGGGCGCGGAGCTGGAGG
GGACCTACGACTGGGGCCGGGGCTTCGTGTCGCTCGCCGCCACCCACGTCGACGGCCGCGACCGCGCCACCCGCGAGAGC
CTGCTCACGGTGCCGCCGGACCGGATCGGCACGACGCTGGGCCTGCGCTTCCTCGCCGACCGGCTCGTCGTGGGCACGCG
CCTGACCCTGGTGGAGGCCCGCACCGACCTGCCCGCCGCCGCCCGGAGCCGGGCCACCAAGGCCTACGGGCTGGTGGACC
TCTTCGCCACCTGCGCGGTCACCGACCGGATCACCGCGGACGTCGCCGTCCAGAACGTCCTCGACCGGCGCTACCGCGCG
TACAACGACGCGCTGGCGAGCCCGGGCCTCGTCGCCAAGGCGTCGCTCAGCATCGCGTTCGCGACCCGGTAG

Upstream 100 bases:

>100_bases
CGCGTGCGGGACTGATCGGACTTCGCGGCTCCCGGGCGGCGTCCGGCCCGCGCGGGCAGGCAATGCGCGGCGCGCGGGCC
AGCAATCCCGGAAATGTCGG

Downstream 100 bases:

>100_bases
GCGCGGCTAGCGGTAGCGCGACGGGTGGTACTCCCGGTAGCTCAGGCCGATCACGGCCGCGAGCAGGCCGGCTCCCCGGC
ACAGCGTGTAGCCGCCGCCG

Product: TonB-dependent heme/hemoglobin receptor family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 743

Protein sequence:

>743_residues
MHISVAIGETIFSKPAIRQPALWNDCVRAAVIMPYASHRALVALGVVLATLPGARAEEAGQAALPEPAIGLDTLSVTATK
TAIPAVDALAGTSVVPRAALDRLQPGRLSEVLRDVPGVITQENRNDPAQAINIRGLQDFGRVNVLVDGARQDFQVSGHGA
NGVFYLDPELVGGVDVTRGPTATVYGSGAIGGVAAFRTRSIDDILAPDESAGFVQKQGFGTNGQRFVNSSALGARIGTAA
DVFGQFVFRDTAPYRDGAGLPVPDTGSELNAGLAKLTLRPAEGHALHATALLQRFAFVNGGDTGAGARFANAVQADTVTF
GYRFARPDVPLVDLSLDGYATTTRDALTFLQDSPRGLYGRLGTRAGDRLTYDLATAGFDAHNTARFETGPVAHALTLGGD
GVANRVRTTDQAGGFGAAFTPSGRRELAGAFLQDEIRAAPWLRIVGALRHDGYRLDGGAYRARGARVSPKITVGVAPVGG
LELYGTYAEGYRAPTITETLMEGIHPFPAFAILPNPALRPEVARTVEGGANLRADGVVGPEDALRAKLALFDTAVDGFID
MQAVGPAYYVPAIPGVPASICAARPGRFPCVIPARSYQYRNVARADLSGAELEGTYDWGRGFVSLAATHVDGRDRATRES
LLTVPPDRIGTTLGLRFLADRLVVGTRLTLVEARTDLPAAARSRATKAYGLVDLFATCAVTDRITADVAVQNVLDRRYRA
YNDALASPGLVAKASLSIAFATR

Sequences:

>Translated_743_residues
MHISVAIGETIFSKPAIRQPALWNDCVRAAVIMPYASHRALVALGVVLATLPGARAEEAGQAALPEPAIGLDTLSVTATK
TAIPAVDALAGTSVVPRAALDRLQPGRLSEVLRDVPGVITQENRNDPAQAINIRGLQDFGRVNVLVDGARQDFQVSGHGA
NGVFYLDPELVGGVDVTRGPTATVYGSGAIGGVAAFRTRSIDDILAPDESAGFVQKQGFGTNGQRFVNSSALGARIGTAA
DVFGQFVFRDTAPYRDGAGLPVPDTGSELNAGLAKLTLRPAEGHALHATALLQRFAFVNGGDTGAGARFANAVQADTVTF
GYRFARPDVPLVDLSLDGYATTTRDALTFLQDSPRGLYGRLGTRAGDRLTYDLATAGFDAHNTARFETGPVAHALTLGGD
GVANRVRTTDQAGGFGAAFTPSGRRELAGAFLQDEIRAAPWLRIVGALRHDGYRLDGGAYRARGARVSPKITVGVAPVGG
LELYGTYAEGYRAPTITETLMEGIHPFPAFAILPNPALRPEVARTVEGGANLRADGVVGPEDALRAKLALFDTAVDGFID
MQAVGPAYYVPAIPGVPASICAARPGRFPCVIPARSYQYRNVARADLSGAELEGTYDWGRGFVSLAATHVDGRDRATRES
LLTVPPDRIGTTLGLRFLADRLVVGTRLTLVEARTDLPAAARSRATKAYGLVDLFATCAVTDRITADVAVQNVLDRRYRA
YNDALASPGLVAKASLSIAFATR
>Mature_743_residues
MHISVAIGETIFSKPAIRQPALWNDCVRAAVIMPYASHRALVALGVVLATLPGARAEEAGQAALPEPAIGLDTLSVTATK
TAIPAVDALAGTSVVPRAALDRLQPGRLSEVLRDVPGVITQENRNDPAQAINIRGLQDFGRVNVLVDGARQDFQVSGHGA
NGVFYLDPELVGGVDVTRGPTATVYGSGAIGGVAAFRTRSIDDILAPDESAGFVQKQGFGTNGQRFVNSSALGARIGTAA
DVFGQFVFRDTAPYRDGAGLPVPDTGSELNAGLAKLTLRPAEGHALHATALLQRFAFVNGGDTGAGARFANAVQADTVTF
GYRFARPDVPLVDLSLDGYATTTRDALTFLQDSPRGLYGRLGTRAGDRLTYDLATAGFDAHNTARFETGPVAHALTLGGD
GVANRVRTTDQAGGFGAAFTPSGRRELAGAFLQDEIRAAPWLRIVGALRHDGYRLDGGAYRARGARVSPKITVGVAPVGG
LELYGTYAEGYRAPTITETLMEGIHPFPAFAILPNPALRPEVARTVEGGANLRADGVVGPEDALRAKLALFDTAVDGFID
MQAVGPAYYVPAIPGVPASICAARPGRFPCVIPARSYQYRNVARADLSGAELEGTYDWGRGFVSLAATHVDGRDRATRES
LLTVPPDRIGTTLGLRFLADRLVVGTRLTLVEARTDLPAAARSRATKAYGLVDLFATCAVTDRITADVAVQNVLDRRYRA
YNDALASPGLVAKASLSIAFATR

Specific function: Required for utilization of free heme at low concentrations [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=619, Percent_Identity=22.6171243941842, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790405, Length=153, Percent_Identity=38.562091503268, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR011276
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78078; Mature: 78078

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISVAIGETIFSKPAIRQPALWNDCVRAAVIMPYASHRALVALGVVLATLPGARAEEAG
CEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHCC
QAALPEPAIGLDTLSVTATKTAIPAVDALAGTSVVPRAALDRLQPGRLSEVLRDVPGVIT
CCCCCCCCCCCCEEEEEEHHHHCCHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEE
QENRNDPAQAINIRGLQDFGRVNVLVDGARQDFQVSGHGANGVFYLDPELVGGVDVTRGP
CCCCCCCHHEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCHHCCCEECCCCC
TATVYGSGAIGGVAAFRTRSIDDILAPDESAGFVQKQGFGTNGQRFVNSSALGARIGTAA
CEEEECCCCCCHHHHHHHCCCHHHCCCCCCCCCEECCCCCCCCHHEECCCHHCHHCCHHH
DVFGQFVFRDTAPYRDGAGLPVPDTGSELNAGLAKLTLRPAEGHALHATALLQRFAFVNG
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
GDTGAGARFANAVQADTVTFGYRFARPDVPLVDLSLDGYATTTRDALTFLQDSPRGLYGR
CCCCCCHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHHH
LGTRAGDRLTYDLATAGFDAHNTARFETGPVAHALTLGGDGVANRVRTTDQAGGFGAAFT
CCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCC
PSGRRELAGAFLQDEIRAAPWLRIVGALRHDGYRLDGGAYRARGARVSPKITVGVAPVGG
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEECCCCEECCCCCCCCEEEEEECCCCC
LELYGTYAEGYRAPTITETLMEGIHPFPAFAILPNPALRPEVARTVEGGANLRADGVVGP
EEEEEEHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCEEECCCCCC
EDALRAKLALFDTAVDGFIDMQAVGPAYYVPAIPGVPASICAARPGRFPCVIPARSYQYR
HHHHHHHHHHHHHHHHCEEEEEECCCEEECCCCCCCCHHHHHCCCCCCEEEECCCCCCCC
NVARADLSGAELEGTYDWGRGFVSLAATHVDGRDRATRESLLTVPPDRIGTTLGLRFLAD
CHHHCCCCCCEEECCHHHCCCEEEHEEEECCCCCHHHHHCEEECCCHHHHHHHHHHHHHH
RLVVGTRLTLVEARTDLPAAARSRATKAYGLVDLFATCAVTDRITADVAVQNVLDRRYRA
HHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNDALASPGLVAKASLSIAFATR
HHHHHCCCCEEEEEEEEEEEECC
>Mature Secondary Structure
MHISVAIGETIFSKPAIRQPALWNDCVRAAVIMPYASHRALVALGVVLATLPGARAEEAG
CEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHCC
QAALPEPAIGLDTLSVTATKTAIPAVDALAGTSVVPRAALDRLQPGRLSEVLRDVPGVIT
CCCCCCCCCCCCEEEEEEHHHHCCHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEE
QENRNDPAQAINIRGLQDFGRVNVLVDGARQDFQVSGHGANGVFYLDPELVGGVDVTRGP
CCCCCCCHHEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCHHCCCEECCCCC
TATVYGSGAIGGVAAFRTRSIDDILAPDESAGFVQKQGFGTNGQRFVNSSALGARIGTAA
CEEEECCCCCCHHHHHHHCCCHHHCCCCCCCCCEECCCCCCCCHHEECCCHHCHHCCHHH
DVFGQFVFRDTAPYRDGAGLPVPDTGSELNAGLAKLTLRPAEGHALHATALLQRFAFVNG
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
GDTGAGARFANAVQADTVTFGYRFARPDVPLVDLSLDGYATTTRDALTFLQDSPRGLYGR
CCCCCCHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHHH
LGTRAGDRLTYDLATAGFDAHNTARFETGPVAHALTLGGDGVANRVRTTDQAGGFGAAFT
CCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCC
PSGRRELAGAFLQDEIRAAPWLRIVGALRHDGYRLDGGAYRARGARVSPKITVGVAPVGG
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEECCCCEECCCCCCCCEEEEEECCCCC
LELYGTYAEGYRAPTITETLMEGIHPFPAFAILPNPALRPEVARTVEGGANLRADGVVGP
EEEEEEHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCEEECCCCCC
EDALRAKLALFDTAVDGFIDMQAVGPAYYVPAIPGVPASICAARPGRFPCVIPARSYQYR
HHHHHHHHHHHHHHHHCEEEEEECCCEEECCCCCCCCHHHHHCCCCCCEEEECCCCCCCC
NVARADLSGAELEGTYDWGRGFVSLAATHVDGRDRATRESLLTVPPDRIGTTLGLRFLAD
CHHHCCCCCCEEECCHHHCCCEEEHEEEECCCCCHHHHHCEEECCCHHHHHHHHHHHHHH
RLVVGTRLTLVEARTDLPAAARSRATKAYGLVDLFATCAVTDRITADVAVQNVLDRRYRA
HHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNDALASPGLVAKASLSIAFATR
HHHHHCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751272 [H]