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The map label for this gene is serB [C]

Identifier: 170750920

GI number: 170750920

Start: 4809287

End: 4810180

Strand: Reverse

Name: serB [C]

Synonym: Mrad2831_4531

Alternate gene names: 170750920

Gene position: 4810180-4809287 (Counterclockwise)

Preceding gene: 170750922

Following gene: 170750912

Centisome position: 79.14

GC content: 74.27

Gene sequence:

>894_bases
ATGCTGGTCGCGATCCTGATAGCAAACCCGGATCGGCCGTCCATCACCGACGCGGTGCTGGCCGAGACGCGCGCCGTGCT
GCGGACGGAGCACCAGCCGCGGATCCTGCACGGGGAGGTGGCGGCCGAGCTGCTGGTGCCGGGCGAGCCCGCGGCCGCGG
CGTCCCTCACCGACAGGCTGCGGACGGCGCTCGCCGGCGAGCCGATCGACCTCGCGGTGCTGCCCGCCGACGCGCACCGG
CGCAAGCGCCTGTTCCTGGCCGACATGGACTCCACCATGATCGAGCAGGAATGCATCGACGAGCTCGCCGGGACGCTCGG
CCTCAAGGACCGCGTGGCGGCGATCACCGAGCGGGCGATGCGGGGCGAGATCGCCTTCGAGCCGGCCCTGCGCGAGCGCG
TCGCGCTGCTGAAGGACATCCCGGTCGGCGCCGTCGACGGGCTGATCGCCGAGCACCTGACCCTGACCCCGGGCGGCCGC
ACGCTGGTGCGGACGATGCGGGCGCACGGCGCCCATACCTGCCTGGTCTCCGGGGGCTTCACGCTGTTCACCGGCCCGAT
CGCCGCGATGATCGGCTTCGACGAGCACCGGTCCAACGTGCTGGGCGTGGCGGACGGGCGGCTCACCGGCCGCGTCGAGG
ACCCGATCGTCGGGAAGGCCGAGAAGCGCGCGACGCTGATCGCGCTGCGCGGAGATCTGGGCCTCGGCGCCGCCGAGACC
CTCGCGGTCGGCGACGGCGCCAACGACCTCGACATGCTGGGCGAGGCCGGCCTCGGGGTGGCGTTCCGGGCGAAGCCCGC
GGTCGCGGCCGCGGCGCGGGTCCGGGTCGAGCACGGCGACCTCACCGCGCTCCTGTACCTGCAAGGCTACGCGGCGGCGG
AGTTCGTCGGGTGA

Upstream 100 bases:

>100_bases
GCCAGCGCCGACTTGCCCGAGGCGGTGGGCCCTGCGATGAGGATCGCGGCCGGGCGCCGCCCGGCTTCCTCCCGGTCTGG
CGGCAAGGCGAAACTCCACG

Downstream 100 bases:

>100_bases
GGCTCAGTGCAGGGTGCGGGTCAGGGCGATGACCGCGCCGAGCACCGCCAGGGTCTGAAAGCCGATCGCGCCGACGAGCC
AGCGTACCGTCTCGACCTTC

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLVAILIANPDRPSITDAVLAETRAVLRTEHQPRILHGEVAAELLVPGEPAAAASLTDRLRTALAGEPIDLAVLPADAHR
RKRLFLADMDSTMIEQECIDELAGTLGLKDRVAAITERAMRGEIAFEPALRERVALLKDIPVGAVDGLIAEHLTLTPGGR
TLVRTMRAHGAHTCLVSGGFTLFTGPIAAMIGFDEHRSNVLGVADGRLTGRVEDPIVGKAEKRATLIALRGDLGLGAAET
LAVGDGANDLDMLGEAGLGVAFRAKPAVAAAARVRVEHGDLTALLYLQGYAAAEFVG

Sequences:

>Translated_297_residues
MLVAILIANPDRPSITDAVLAETRAVLRTEHQPRILHGEVAAELLVPGEPAAAASLTDRLRTALAGEPIDLAVLPADAHR
RKRLFLADMDSTMIEQECIDELAGTLGLKDRVAAITERAMRGEIAFEPALRERVALLKDIPVGAVDGLIAEHLTLTPGGR
TLVRTMRAHGAHTCLVSGGFTLFTGPIAAMIGFDEHRSNVLGVADGRLTGRVEDPIVGKAEKRATLIALRGDLGLGAAET
LAVGDGANDLDMLGEAGLGVAFRAKPAVAAAARVRVEHGDLTALLYLQGYAAAEFVG
>Mature_297_residues
MLVAILIANPDRPSITDAVLAETRAVLRTEHQPRILHGEVAAELLVPGEPAAAASLTDRLRTALAGEPIDLAVLPADAHR
RKRLFLADMDSTMIEQECIDELAGTLGLKDRVAAITERAMRGEIAFEPALRERVALLKDIPVGAVDGLIAEHLTLTPGGR
TLVRTMRAHGAHTCLVSGGFTLFTGPIAAMIGFDEHRSNVLGVADGRLTGRVEDPIVGKAEKRATLIALRGDLGLGAAET
LAVGDGANDLDMLGEAGLGVAFRAKPAVAAAARVRVEHGDLTALLYLQGYAAAEFVG

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=181, Percent_Identity=32.0441988950276, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790849, Length=235, Percent_Identity=41.7021276595745, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI115534454, Length=171, Percent_Identity=32.1637426900585, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=171, Percent_Identity=32.1637426900585, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=173, Percent_Identity=31.7919075144509, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=245, Percent_Identity=36.3265306122449, Blast_Score=155, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24661601, Length=196, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31184; Mature: 31184

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAILIANPDRPSITDAVLAETRAVLRTEHQPRILHGEVAAELLVPGEPAAAASLTDRL
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHEEECCCCCHHHHHHHHHH
RTALAGEPIDLAVLPADAHRRKRLFLADMDSTMIEQECIDELAGTLGLKDRVAAITERAM
HHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RGEIAFEPALRERVALLKDIPVGAVDGLIAEHLTLTPGGRTLVRTMRAHGAHTCLVSGGF
CCCCEECHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEEECCC
TLFTGPIAAMIGFDEHRSNVLGVADGRLTGRVEDPIVGKAEKRATLIALRGDLGLGAAET
EEEHHHHHHHHCCHHHCCCEEEEECCCEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHE
LAVGDGANDLDMLGEAGLGVAFRAKPAVAAAARVRVEHGDLTALLYLQGYAAAEFVG
EEECCCCCHHHHHCCCCCCEEEECCCHHHHHHEEEEECCCEEEEEEEECCCHHHCCC
>Mature Secondary Structure
MLVAILIANPDRPSITDAVLAETRAVLRTEHQPRILHGEVAAELLVPGEPAAAASLTDRL
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHEEECCCCCHHHHHHHHHH
RTALAGEPIDLAVLPADAHRRKRLFLADMDSTMIEQECIDELAGTLGLKDRVAAITERAM
HHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RGEIAFEPALRERVALLKDIPVGAVDGLIAEHLTLTPGGRTLVRTMRAHGAHTCLVSGGF
CCCCEECHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEEECCC
TLFTGPIAAMIGFDEHRSNVLGVADGRLTGRVEDPIVGKAEKRATLIALRGDLGLGAAET
EEEHHHHHHHHCCHHHCCCEEEEECCCEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHE
LAVGDGANDLDMLGEAGLGVAFRAKPAVAAAARVRVEHGDLTALLYLQGYAAAEFVG
EEECCCCCHHHHHCCCCCCEEEECCCHHHHHHEEEEECCCEEEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]