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The map label for this gene is 170750900

Identifier: 170750900

GI number: 170750900

Start: 4791218

End: 4791712

Strand: Reverse

Name: 170750900

Synonym: Mrad2831_4511

Alternate gene names: NA

Gene position: 4791712-4791218 (Counterclockwise)

Preceding gene: 170750902

Following gene: 170750898

Centisome position: 78.84

GC content: 70.71

Gene sequence:

>495_bases
ATGGAGACGGGCGGGACCGCCACGAGCCACGTGCCGGACGAGCTGAAGGCGGAGTCGCACCGGGGCGACCCCTTCGCGGC
CGCCGTGCGGGCGACCCGGATGCCGATGATCATCACCGATCCGGCCCAGCACGACAATCCGATCGTCTTCGTGAACGACG
CGTTCCTGAAGCTGACCGGCTACACCCGGATGGAGGTGGTCGGCCGCAACTGCCGCTTCCTGCAGGGGCCCGACACCGAG
GCGGCGGCCGTGGACCGCCTCCGCGCGGCCATCCGGCGGGAGGAGGATATCCGGGTCGACCTCCTCAACTACCGCAAGGA
CGGCTCGACCTTCCAGAACGCCCTCTATGTCGGGCCGGTGCGGGACGAGGCGGGCCGGGTGGTCTACTTCTTCGCCTCGC
AGCTCGACGTCAGCGAGCACTACGCGCTGACCGCCGAGATCGAGCGGCTGAAGGCCGCCCTGGCCGAGGCCGAGGCCAAG
CTCGCGGCCCGCTAG

Upstream 100 bases:

>100_bases
GAGCCGCGAGACTGGATCTCGCGGGCAAATTCCGGCTTGTTGCCCGGAGAGATACTGGTCGGATGGCCGCCCTGCGCGGC
GTTATGAGGGGCTGATCCGG

Downstream 100 bases:

>100_bases
GCCGCCCGGAGGATCAGGGCTTCGTCAGGAACCCGATCGGCTCGCGGCCCGGCTGGCCGAGCCAGAGCAGGACCGCGCCG
AGCCCGAGGCCGATCAGGGA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
METGGTATSHVPDELKAESHRGDPFAAAVRATRMPMIITDPAQHDNPIVFVNDAFLKLTGYTRMEVVGRNCRFLQGPDTE
AAAVDRLRAAIRREEDIRVDLLNYRKDGSTFQNALYVGPVRDEAGRVVYFFASQLDVSEHYALTAEIERLKAALAEAEAK
LAAR

Sequences:

>Translated_164_residues
METGGTATSHVPDELKAESHRGDPFAAAVRATRMPMIITDPAQHDNPIVFVNDAFLKLTGYTRMEVVGRNCRFLQGPDTE
AAAVDRLRAAIRREEDIRVDLLNYRKDGSTFQNALYVGPVRDEAGRVVYFFASQLDVSEHYALTAEIERLKAALAEAEAK
LAAR
>Mature_164_residues
METGGTATSHVPDELKAESHRGDPFAAAVRATRMPMIITDPAQHDNPIVFVNDAFLKLTGYTRMEVVGRNCRFLQGPDTE
AAAVDRLRAAIRREEDIRVDLLNYRKDGSTFQNALYVGPVRDEAGRVVYFFASQLDVSEHYALTAEIERLKAALAEAEAK
LAAR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI13540549, Length=104, Percent_Identity=41.3461538461538, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI27886651, Length=104, Percent_Identity=41.3461538461538, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI6912446, Length=95, Percent_Identity=42.1052631578947, Blast_Score=80, Evalue=7e-16,
Organism=Homo sapiens, GI38569493, Length=95, Percent_Identity=38.9473684210526, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136946, Length=145, Percent_Identity=28.2758620689655, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 18179; Mature: 18179

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METGGTATSHVPDELKAESHRGDPFAAAVRATRMPMIITDPAQHDNPIVFVNDAFLKLTG
CCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCEEEEEC
YTRMEVVGRNCRFLQGPDTEAAAVDRLRAAIRREEDIRVDLLNYRKDGSTFQNALYVGPV
CEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHCEEEECCC
RDEAGRVVYFFASQLDVSEHYALTAEIERLKAALAEAEAKLAAR
CCCCCCEEEEEECCCCCCHHEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METGGTATSHVPDELKAESHRGDPFAAAVRATRMPMIITDPAQHDNPIVFVNDAFLKLTG
CCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCEEEEEC
YTRMEVVGRNCRFLQGPDTEAAAVDRLRAAIRREEDIRVDLLNYRKDGSTFQNALYVGPV
CEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHCEEEECCC
RDEAGRVVYFFASQLDVSEHYALTAEIERLKAALAEAEAKLAAR
CCCCCCEEEEEECCCCCCHHEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA