Click here to switch to the map view.

The map label for this gene is speF [H]

Identifier: 170750793

GI number: 170750793

Start: 4669211

End: 4671556

Strand: Reverse

Name: speF [H]

Synonym: Mrad2831_4404

Alternate gene names: 170750793

Gene position: 4671556-4669211 (Counterclockwise)

Preceding gene: 170750794

Following gene: 170750792

Centisome position: 76.86

GC content: 68.84

Gene sequence:

>2346_bases
ATGGACTTCCACCGCCGCTTCACGGTCCTGATGTGCGCCCCGGCCTTCGACCCGGACGATCTCGAGGGCGCGCGCGTCAA
CCAGATCGTCGCGGCCGTGGAGCAGCGCGGCTTCGAGGTGGTGCGCGCCCGGCGCGTCGAGGACGCGGCCATCGCGGTCC
AGACCGACGCGGCGGTCGGCTGCCTCGTGGTCGACTGGGGCAAGCGCGGCCTCGACGGCAAGGCGGCCGCCCTCATCGAC
ATGATGCGCCGGCGCGGCCTGGAGATGCCGATCGTCATCATGGTCCGCCGCAAGCGGCTGGAGGACATCCCGGTCGAGCT
CCTCGACTTCATCGACGGCTACATCTTCCTCGCCGAGGAGACGCCGGAATTCATCGCCCGCGGCCTCGTCAGCCGGGTCA
CGCAGTACGCCGAGACCCTCAAGACGCCGTTCTTCGGCGCGCTCGTCGACTACGCCGAGAAGGGCAACCAGCTCTGGACC
TGCCCGGGGCACAACGGCGGCATCTTCTACAACCGGTCCCCCATCGGCCGGATCTTCGTGGAGCACCTGGGCGAGGCGAT
CTTCCGCGACGACCTCGACAACTCGGTCCTCGACCTCGGCGACCTGCTGACCCACGAGGGCCCGGCGCTGAAGGCCCAGA
AGGAGGCCGCCAAGATCTTCGGGGCGGAGAAGACCTACTTCGTCCTCAACGGCACCTCGGCGTCCAACAAGATCGTCCTG
TCCTCCCTGGTGGCGGAGGACGACCTCGTCCTGTTCGACCGCAACAACCACAAGGCGGCCCACCACGGCGCCCTGTTCCT
GGGCGGCGGCATCCCGATCTTCCTGGAAACGGATCGGAACGCGTACGGCCTGATCGGGCCGATCTTCCACGAAGCTCTCG
ACGAAGGCCGGATCCGGGAGAAGATCCGCCGGAACCCGCTGGTGACCGATCCGGAGGCGTGGCGCCGGGAGCGGCCGTTC
CGCGTCGCGGTGATCGAGCAGTGCACCTACGACGGCACGATCTACGACGCCCAGGAGATCCTGGAGAAGATCGGCCACCT
CTGCGACTACATCCTGTTCGACGAGGCCTGGGCGGGCTTCATGAAGTTCCACCCGCTCTACGCAAGGCGCTTCGCCATGG
GGCTGACGGGCCTCGACGAGACCTCGCCCGGCATCGTCGCCACGCAGTCGACCCACAAGCAGCTCGCGAGCTTCAGCCAG
GCCTCGCAGATCCACACCCGCGACGGCCATATCCGCGGCCAGACCCGGCGGGTCGAGCACAAGCGGCTCAACGAGAGCTT
CCTCGTCCACGCCTCGACCTCGCCCTTCTACCCGCTCTTCGCCTCCCTCGACGTCGGCGCCCAGATGATGAAGGGGCGCT
CCGGCATGATCCTGTGGGACGACACGATCCGCCTCGGGATCGAGTGGCGCAAGAAGGTCCGGGCGATCCGGCGGGAATTC
GAGGAGAACGAGCGCGATCCCGCCCGGCGCTGGTTCTTCGACCCGTTCGTGCCGGACGTGACGGTGAACGCCGACGGCGC
CGAGGTGCCGTGGGAGAGCGTGCCGACCGACGAGCTCGCCGCGACGCCGCGCCACTGGGAGCTGAAGCCGGGCGCGCGCT
GGCACGGCTTCAGCCACGTGGCGCCGGGCTACGCCATTACCGACCCGAACAAGCTCACCGTGCTGACCCCCGGCTTCGAC
CGGCACACGGGGGCCTACGCCCAGCACGGCGTGCCGGCGCCGATCGTGGCGCAATACCTGCGTGAGAACCGGATCGTCGC
CGAGAAGAACGACCTGAACTCGCTGCTCTTCCTGCTGACCCCGGGGGTCGAATCCTCCAAGGCCGGCACGCTGATCTCGG
GCCTCGTCGCCTTCAAGCGGCTCCACGACGACAACGTCGCGCTGGAGGAGGCCATGCCGGAATTCGTCAACCGCCGGCCG
AACCGCTACCGCGGCGTGCGCCTGCGCGACCTCTGCGGCGAGTTCCACGCCTTCCACCGGGAGGCCGGCACCTCCGCGCT
GCAGCGGCGCCAATTCGCCCCCGAGCACCTGCCCGAGATGGTGATGCCGCCCAAGAAGGCCGCCCAGCTGCTGACCCGCA
ACACGGTCGACTACGTGCCGATCGCCGAGGCCGAGGGGCGGATCGCCACCACGCTGATGCTGGTCTACCCGCCGGGCATC
GGCACGGTTCTGCCGGGCGAGCGCCTGGACGAAAGGGCCAAGCCCATGCTCGACTATTTCAAGATGTTCGAGGCCTCCGC
CAACCTGTTCCCGGGCTTCGAGGCCGAGATCCAGGGCGTCTACCGCGAGGTCGACCCGGACGGGCGGATCCGCTTCCACA
CCTACGTGGCGCGGGAGGGGGTCTGA

Upstream 100 bases:

>100_bases
CTTTCGTCCGGACCGCGACCGCCCGCCGCGCACCGTGTCATGCAATCGTCGCAGACGGGCCGGAAAGCCACCCGCTGCAT
CCGAGGCCAGAGAGGGCTCC

Downstream 100 bases:

>100_bases
TGGAGATCGAGGTCGAGACGCCCGGCCCGGTCCCGGCCCGGTCCTGCCCCGACATCGTCATCCGCCCGTCCTCGGACGCC
GATGTCGAGGCGATGGTGGC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 781

Protein sequence:

>781_residues
MDFHRRFTVLMCAPAFDPDDLEGARVNQIVAAVEQRGFEVVRARRVEDAAIAVQTDAAVGCLVVDWGKRGLDGKAAALID
MMRRRGLEMPIVIMVRRKRLEDIPVELLDFIDGYIFLAEETPEFIARGLVSRVTQYAETLKTPFFGALVDYAEKGNQLWT
CPGHNGGIFYNRSPIGRIFVEHLGEAIFRDDLDNSVLDLGDLLTHEGPALKAQKEAAKIFGAEKTYFVLNGTSASNKIVL
SSLVAEDDLVLFDRNNHKAAHHGALFLGGGIPIFLETDRNAYGLIGPIFHEALDEGRIREKIRRNPLVTDPEAWRRERPF
RVAVIEQCTYDGTIYDAQEILEKIGHLCDYILFDEAWAGFMKFHPLYARRFAMGLTGLDETSPGIVATQSTHKQLASFSQ
ASQIHTRDGHIRGQTRRVEHKRLNESFLVHASTSPFYPLFASLDVGAQMMKGRSGMILWDDTIRLGIEWRKKVRAIRREF
EENERDPARRWFFDPFVPDVTVNADGAEVPWESVPTDELAATPRHWELKPGARWHGFSHVAPGYAITDPNKLTVLTPGFD
RHTGAYAQHGVPAPIVAQYLRENRIVAEKNDLNSLLFLLTPGVESSKAGTLISGLVAFKRLHDDNVALEEAMPEFVNRRP
NRYRGVRLRDLCGEFHAFHREAGTSALQRRQFAPEHLPEMVMPPKKAAQLLTRNTVDYVPIAEAEGRIATTLMLVYPPGI
GTVLPGERLDERAKPMLDYFKMFEASANLFPGFEAEIQGVYREVDPDGRIRFHTYVAREGV

Sequences:

>Translated_781_residues
MDFHRRFTVLMCAPAFDPDDLEGARVNQIVAAVEQRGFEVVRARRVEDAAIAVQTDAAVGCLVVDWGKRGLDGKAAALID
MMRRRGLEMPIVIMVRRKRLEDIPVELLDFIDGYIFLAEETPEFIARGLVSRVTQYAETLKTPFFGALVDYAEKGNQLWT
CPGHNGGIFYNRSPIGRIFVEHLGEAIFRDDLDNSVLDLGDLLTHEGPALKAQKEAAKIFGAEKTYFVLNGTSASNKIVL
SSLVAEDDLVLFDRNNHKAAHHGALFLGGGIPIFLETDRNAYGLIGPIFHEALDEGRIREKIRRNPLVTDPEAWRRERPF
RVAVIEQCTYDGTIYDAQEILEKIGHLCDYILFDEAWAGFMKFHPLYARRFAMGLTGLDETSPGIVATQSTHKQLASFSQ
ASQIHTRDGHIRGQTRRVEHKRLNESFLVHASTSPFYPLFASLDVGAQMMKGRSGMILWDDTIRLGIEWRKKVRAIRREF
EENERDPARRWFFDPFVPDVTVNADGAEVPWESVPTDELAATPRHWELKPGARWHGFSHVAPGYAITDPNKLTVLTPGFD
RHTGAYAQHGVPAPIVAQYLRENRIVAEKNDLNSLLFLLTPGVESSKAGTLISGLVAFKRLHDDNVALEEAMPEFVNRRP
NRYRGVRLRDLCGEFHAFHREAGTSALQRRQFAPEHLPEMVMPPKKAAQLLTRNTVDYVPIAEAEGRIATTLMLVYPPGI
GTVLPGERLDERAKPMLDYFKMFEASANLFPGFEAEIQGVYREVDPDGRIRFHTYVAREGV
>Mature_781_residues
MDFHRRFTVLMCAPAFDPDDLEGARVNQIVAAVEQRGFEVVRARRVEDAAIAVQTDAAVGCLVVDWGKRGLDGKAAALID
MMRRRGLEMPIVIMVRRKRLEDIPVELLDFIDGYIFLAEETPEFIARGLVSRVTQYAETLKTPFFGALVDYAEKGNQLWT
CPGHNGGIFYNRSPIGRIFVEHLGEAIFRDDLDNSVLDLGDLLTHEGPALKAQKEAAKIFGAEKTYFVLNGTSASNKIVL
SSLVAEDDLVLFDRNNHKAAHHGALFLGGGIPIFLETDRNAYGLIGPIFHEALDEGRIREKIRRNPLVTDPEAWRRERPF
RVAVIEQCTYDGTIYDAQEILEKIGHLCDYILFDEAWAGFMKFHPLYARRFAMGLTGLDETSPGIVATQSTHKQLASFSQ
ASQIHTRDGHIRGQTRRVEHKRLNESFLVHASTSPFYPLFASLDVGAQMMKGRSGMILWDDTIRLGIEWRKKVRAIRREF
EENERDPARRWFFDPFVPDVTVNADGAEVPWESVPTDELAATPRHWELKPGARWHGFSHVAPGYAITDPNKLTVLTPGFD
RHTGAYAQHGVPAPIVAQYLRENRIVAEKNDLNSLLFLLTPGVESSKAGTLISGLVAFKRLHDDNVALEEAMPEFVNRRP
NRYRGVRLRDLCGEFHAFHREAGTSALQRRQFAPEHLPEMVMPPKKAAQLLTRNTVDYVPIAEAEGRIATTLMLVYPPGI
GTVLPGERLDERAKPMLDYFKMFEASANLFPGFEAEIQGVYREVDPDGRIRFHTYVAREGV

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=709, Percent_Identity=44.7108603667137, Blast_Score=593, Evalue=1e-170,
Organism=Escherichia coli, GI87082193, Length=703, Percent_Identity=44.2389758179232, Blast_Score=586, Evalue=1e-168,
Organism=Escherichia coli, GI221142684, Length=746, Percent_Identity=32.7077747989276, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1786384, Length=746, Percent_Identity=31.5013404825737, Blast_Score=388, Evalue=1e-108,
Organism=Escherichia coli, GI1790573, Length=740, Percent_Identity=31.4864864864865, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 87979; Mature: 87979

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFHRRFTVLMCAPAFDPDDLEGARVNQIVAAVEQRGFEVVRARRVEDAAIAVQTDAAVG
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCEE
CLVVDWGKRGLDGKAAALIDMMRRRGLEMPIVIMVRRKRLEDIPVELLDFIDGYIFLAEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCHHHHHHHCCEEEEECC
TPEFIARGLVSRVTQYAETLKTPFFGALVDYAEKGNQLWTCPGHNGGIFYNRSPIGRIFV
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCEEECCCCHHHHHH
EHLGEAIFRDDLDNSVLDLGDLLTHEGPALKAQKEAAKIFGAEKTYFVLNGTSASNKIVL
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
SSLVAEDDLVLFDRNNHKAAHHGALFLGGGIPIFLETDRNAYGLIGPIFHEALDEGRIRE
HHHHCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCHHHHH
KIRRNPLVTDPEAWRRERPFRVAVIEQCTYDGTIYDAQEILEKIGHLCDYILFDEAWAGF
HHHCCCCCCCCHHHHHCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
MKFHPLYARRFAMGLTGLDETSPGIVATQSTHKQLASFSQASQIHTRDGHIRGQTRRVEH
HHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KRLNESFLVHASTSPFYPLFASLDVGAQMMKGRSGMILWDDTIRLGIEWRKKVRAIRREF
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEECHHHHHHHHHHHHHH
EENERDPARRWFFDPFVPDVTVNADGAEVPWESVPTDELAATPRHWELKPGARWHGFSHV
HHCCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCCCEECCCCCCCCCCCCC
APGYAITDPNKLTVLTPGFDRHTGAYAQHGVPAPIVAQYLRENRIVAEKNDLNSLLFLLT
CCCCEECCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHCCCEEECCCCCCEEEEEE
PGVESSKAGTLISGLVAFKRLHDDNVALEEAMPEFVNRRPNRYRGVRLRDLCGEFHAFHR
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHH
EAGTSALQRRQFAPEHLPEMVMPPKKAAQLLTRNTVDYVPIAEAEGRIATTLMLVYPPGI
HHHHHHHHHHHCCHHHCHHHCCCHHHHHHHHHCCCCCCEECCCCCCCEEEEEEEEECCCC
GTVLPGERLDERAKPMLDYFKMFEASANLFPGFEAEIQGVYREVDPDGRIRFHTYVAREG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCC
V
C
>Mature Secondary Structure
MDFHRRFTVLMCAPAFDPDDLEGARVNQIVAAVEQRGFEVVRARRVEDAAIAVQTDAAVG
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCEE
CLVVDWGKRGLDGKAAALIDMMRRRGLEMPIVIMVRRKRLEDIPVELLDFIDGYIFLAEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCHHHHHHHCCEEEEECC
TPEFIARGLVSRVTQYAETLKTPFFGALVDYAEKGNQLWTCPGHNGGIFYNRSPIGRIFV
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCEEECCCCHHHHHH
EHLGEAIFRDDLDNSVLDLGDLLTHEGPALKAQKEAAKIFGAEKTYFVLNGTSASNKIVL
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
SSLVAEDDLVLFDRNNHKAAHHGALFLGGGIPIFLETDRNAYGLIGPIFHEALDEGRIRE
HHHHCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCHHHHH
KIRRNPLVTDPEAWRRERPFRVAVIEQCTYDGTIYDAQEILEKIGHLCDYILFDEAWAGF
HHHCCCCCCCCHHHHHCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
MKFHPLYARRFAMGLTGLDETSPGIVATQSTHKQLASFSQASQIHTRDGHIRGQTRRVEH
HHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KRLNESFLVHASTSPFYPLFASLDVGAQMMKGRSGMILWDDTIRLGIEWRKKVRAIRREF
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEECHHHHHHHHHHHHHH
EENERDPARRWFFDPFVPDVTVNADGAEVPWESVPTDELAATPRHWELKPGARWHGFSHV
HHCCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCCCEECCCCCCCCCCCCC
APGYAITDPNKLTVLTPGFDRHTGAYAQHGVPAPIVAQYLRENRIVAEKNDLNSLLFLLT
CCCCEECCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHCCCEEECCCCCCEEEEEE
PGVESSKAGTLISGLVAFKRLHDDNVALEEAMPEFVNRRPNRYRGVRLRDLCGEFHAFHR
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHH
EAGTSALQRRQFAPEHLPEMVMPPKKAAQLLTRNTVDYVPIAEAEGRIATTLMLVYPPGI
HHHHHHHHHHHCCHHHCHHHCCCHHHHHHHHHCCCCCCEECCCCCCCEEEEEEEEECCCC
GTVLPGERLDERAKPMLDYFKMFEASANLFPGFEAEIQGVYREVDPDGRIRFHTYVAREG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]