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The map label for this gene is gsiC [H]

Identifier: 170750769

GI number: 170750769

Start: 4645385

End: 4646302

Strand: Reverse

Name: gsiC [H]

Synonym: Mrad2831_4380

Alternate gene names: 170750769

Gene position: 4646302-4645385 (Counterclockwise)

Preceding gene: 170750770

Following gene: 170750768

Centisome position: 76.45

GC content: 69.5

Gene sequence:

>918_bases
ATGCTGGCCTTCACGGTCCGGCGCGTGCTGGTCGCCCTGGCGGTGGCCGTCACCGTCTCGGTGGCGAGCTTCCTGCTCCT
CCACCTCTCCGGCGACCTCGCCACCGCCATCGCCGGCCCGGAGGCCACGGGCCCCCAGATCGCGCAGATCCGCCGGGATT
ACGGCCTCGACCAGCCGCTGCTGACCCAGTTCCTCACCTGGGGCTGGCGGGCGCTGCACCTCGATTTCGGCAACTCCTTC
TATTTCCGCGAGAGCGTGATCGACCTGCTGGCCGCCCGCCTGCCGATCACCCTCTACCTCGGCATCATCGCGCTGGCCGT
CGCGCTGTTCGTGGCGATCCCGCTCGGCGTCGTCGCCGCCGTGAAGCGGGACACGTGGATCGACCGGACGGCACTGGCCG
TCTCGGTGCTCGGCCAGGCGATGCCGAGCTTCTGGTTCGGCCTGACGCTGATCCTGATCTTCTCCGTCAATCTCCGCTGG
CTGCCGGTCTCCGGCAACGCCACGTGGAAGAACTTCGTCCTGCCCGCGGTGGCGCTCGGCTACTACGCGATGCCGGCGGT
GATGCGCCTCACCCGCAACGGCATGCTGGAGGTGCTGGCCTCCGACTACGTCCGCACCGCCCGCGCCAAGGGGCTGCCGC
CCCGGAAGATCCTGGTCCGGCACGCGCTGCGCAACGCCGTGATCCCGGTGATCGCCCTGTCGGCGGTGCAGTTCGGCTTC
ATGCTCGGCGGCTCGATCGTGATCGAGGCGGTGTTCTCGCTCCAGGGCCTCGGGCAGCTCGCCTGGGAATCCATCGCCCG
CAACGACTTTCCCGTCGTCCAGGCGATCGTGCTGGTGCTCGCCATGATCTACATCGGCCTGACGCTCGCCGCCGACCTCC
TGAACGCCTTCCTCGACCCGCGCCTGCGCCAGTCGTGA

Upstream 100 bases:

>100_bases
ACCCTGTCCCTCTCCCGCACGGGAGAGGGGACCCGCGATCGGTCCGGATGCCGTGAGCGCCGACCGATCCGTCTCCGATC
GCCACGAAGGAGCCTGAGCC

Downstream 100 bases:

>100_bases
GGATCCGCCGATGAGCCTCCCCCCCGACACGGCGGCGCTCGCCGCCCCGGCCCTGCCCCCGGACGCGCCGGTCGCGCTGG
CGCCGGTCCCCTCCCCCACC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLAFTVRRVLVALAVAVTVSVASFLLLHLSGDLATAIAGPEATGPQIAQIRRDYGLDQPLLTQFLTWGWRALHLDFGNSF
YFRESVIDLLAARLPITLYLGIIALAVALFVAIPLGVVAAVKRDTWIDRTALAVSVLGQAMPSFWFGLTLILIFSVNLRW
LPVSGNATWKNFVLPAVALGYYAMPAVMRLTRNGMLEVLASDYVRTARAKGLPPRKILVRHALRNAVIPVIALSAVQFGF
MLGGSIVIEAVFSLQGLGQLAWESIARNDFPVVQAIVLVLAMIYIGLTLAADLLNAFLDPRLRQS

Sequences:

>Translated_305_residues
MLAFTVRRVLVALAVAVTVSVASFLLLHLSGDLATAIAGPEATGPQIAQIRRDYGLDQPLLTQFLTWGWRALHLDFGNSF
YFRESVIDLLAARLPITLYLGIIALAVALFVAIPLGVVAAVKRDTWIDRTALAVSVLGQAMPSFWFGLTLILIFSVNLRW
LPVSGNATWKNFVLPAVALGYYAMPAVMRLTRNGMLEVLASDYVRTARAKGLPPRKILVRHALRNAVIPVIALSAVQFGF
MLGGSIVIEAVFSLQGLGQLAWESIARNDFPVVQAIVLVLAMIYIGLTLAADLLNAFLDPRLRQS
>Mature_305_residues
MLAFTVRRVLVALAVAVTVSVASFLLLHLSGDLATAIAGPEATGPQIAQIRRDYGLDQPLLTQFLTWGWRALHLDFGNSF
YFRESVIDLLAARLPITLYLGIIALAVALFVAIPLGVVAAVKRDTWIDRTALAVSVLGQAMPSFWFGLTLILIFSVNLRW
LPVSGNATWKNFVLPAVALGYYAMPAVMRLTRNGMLEVLASDYVRTARAKGLPPRKILVRHALRNAVIPVIALSAVQFGF
MLGGSIVIEAVFSLQGLGQLAWESIARNDFPVVQAIVLVLAMIYIGLTLAADLLNAFLDPRLRQS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=304, Percent_Identity=41.4473684210526, Blast_Score=234, Evalue=4e-63,
Organism=Escherichia coli, GI1789888, Length=309, Percent_Identity=38.5113268608414, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=36.6863905325444, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=34.8534201954397, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787761, Length=318, Percent_Identity=34.5911949685535, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788504, Length=284, Percent_Identity=32.0422535211268, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787550, Length=260, Percent_Identity=32.3076923076923, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33192; Mature: 33192

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAFTVRRVLVALAVAVTVSVASFLLLHLSGDLATAIAGPEATGPQIAQIRRDYGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHH
LTQFLTWGWRALHLDFGNSFYFRESVIDLLAARLPITLYLGIIALAVALFVAIPLGVVAA
HHHHHHCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRDTWIDRTALAVSVLGQAMPSFWFGLTLILIFSVNLRWLPVSGNATWKNFVLPAVALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
YYAMPAVMRLTRNGMLEVLASDYVRTARAKGLPPRKILVRHALRNAVIPVIALSAVQFGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGGSIVIEAVFSLQGLGQLAWESIARNDFPVVQAIVLVLAMIYIGLTLAADLLNAFLDP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RLRQS
HHCCC
>Mature Secondary Structure
MLAFTVRRVLVALAVAVTVSVASFLLLHLSGDLATAIAGPEATGPQIAQIRRDYGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHH
LTQFLTWGWRALHLDFGNSFYFRESVIDLLAARLPITLYLGIIALAVALFVAIPLGVVAA
HHHHHHCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRDTWIDRTALAVSVLGQAMPSFWFGLTLILIFSVNLRWLPVSGNATWKNFVLPAVALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
YYAMPAVMRLTRNGMLEVLASDYVRTARAKGLPPRKILVRHALRNAVIPVIALSAVQFGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGGSIVIEAVFSLQGLGQLAWESIARNDFPVVQAIVLVLAMIYIGLTLAADLLNAFLDP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RLRQS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA