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The map label for this gene is dppC [H]

Identifier: 170750768

GI number: 170750768

Start: 4644439

End: 4645374

Strand: Reverse

Name: dppC [H]

Synonym: Mrad2831_4379

Alternate gene names: 170750768

Gene position: 4645374-4644439 (Counterclockwise)

Preceding gene: 170750769

Following gene: 170750767

Centisome position: 76.43

GC content: 72.22

Gene sequence:

>936_bases
ATGAGCCTCCCCCCCGACACGGCGGCGCTCGCCGCCCCGGCCCTGCCCCCGGACGCGCCGGTCGCGCTGGCGCCGGTCCC
CTCCCCCACCCGCCTGGTCCTGCGGCGGGGCCTGCGCCACACCGGCTTCCTGATCGGCGCCGGGATCCTCGGGCTGATCG
TGCTGGCGGCGCTCGCCGCCCCGCTCATCGCGCCCCACGACCCCTACGCGCAGGACGTGTCCCGCCGCCTGATCCCGCCG
GTCTGGCAGGCCAAGGGCACCTGGGCGCACGTGCTCGGCACCGACAAGCTCGGCCGCGACTACCTGAGCCGCCTGCTCTA
CGGCGGCCAGATCTCCCTCCTGATCGGGCTCTCGGCGGCGCTGATCTCCGGCCTGATCGGCACGACGCTGGGGCTCTGCG
CCGGCTATTTCGGCGGCTGGGTCGACTCGGTGGTGAGCTACATCGTCACCACGCGGCTCGCCATGCCGGTGGTGCTGGTG
GCGCTGGCCATGGCGGCGCTGGTCGGCGGCTCGCTCAAGGTGGTGGTGCTGGTGCTGGGCTTCCTGCTCTGGGACCGCTT
CGCCGTGGTGACCCGGGCCGCCACCCAGCAGATCCGCAACCAGGATTTCGTCTCGGCCGCCCGCGCCGCGGGGCTCACGG
ATCTGCGGATCATCCGCCAGGAGATCCTGCCCAACATCATGAACGCCCTGATCGTCGTGGCGACCCTGGAGATGGCCCAC
GCGATCCTGCTGGAGGCCGCCCTGTCGTTCCTCGGGCTCGGCGTGCAGCCGCCCCTGCCCTCCTGGGGCCTGATGATCGC
CGAGGGCAAGCAGTACATGTTCTTCCAGCCCTGGGTGATCACCATCCCGGGCGTGGCGCTCCTCCTGCTCGTGCTGGCGA
TCAATCTCCTGGGCGACGGCCTGCGCGACATCACGGCGCCCGAGGCGCGCAATTGA

Upstream 100 bases:

>100_bases
GTGCTGGTGCTCGCCATGATCTACATCGGCCTGACGCTCGCCGCCGACCTCCTGAACGCCTTCCTCGACCCGCGCCTGCG
CCAGTCGTGAGGATCCGCCG

Downstream 100 bases:

>100_bases
CGCCTCCGCCGGGCCAGAGCCGGCCGGCAGATTAACGAAATGTTTCACGGGAAACACACCATGACGCGAGACGCCGCCAT
CGCGCGCGCCACGGAGGCCT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSLPPDTAALAAPALPPDAPVALAPVPSPTRLVLRRGLRHTGFLIGAGILGLIVLAALAAPLIAPHDPYAQDVSRRLIPP
VWQAKGTWAHVLGTDKLGRDYLSRLLYGGQISLLIGLSAALISGLIGTTLGLCAGYFGGWVDSVVSYIVTTRLAMPVVLV
ALAMAALVGGSLKVVVLVLGFLLWDRFAVVTRAATQQIRNQDFVSAARAAGLTDLRIIRQEILPNIMNALIVVATLEMAH
AILLEAALSFLGLGVQPPLPSWGLMIAEGKQYMFFQPWVITIPGVALLLLVLAINLLGDGLRDITAPEARN

Sequences:

>Translated_311_residues
MSLPPDTAALAAPALPPDAPVALAPVPSPTRLVLRRGLRHTGFLIGAGILGLIVLAALAAPLIAPHDPYAQDVSRRLIPP
VWQAKGTWAHVLGTDKLGRDYLSRLLYGGQISLLIGLSAALISGLIGTTLGLCAGYFGGWVDSVVSYIVTTRLAMPVVLV
ALAMAALVGGSLKVVVLVLGFLLWDRFAVVTRAATQQIRNQDFVSAARAAGLTDLRIIRQEILPNIMNALIVVATLEMAH
AILLEAALSFLGLGVQPPLPSWGLMIAEGKQYMFFQPWVITIPGVALLLLVLAINLLGDGLRDITAPEARN
>Mature_310_residues
SLPPDTAALAAPALPPDAPVALAPVPSPTRLVLRRGLRHTGFLIGAGILGLIVLAALAAPLIAPHDPYAQDVSRRLIPPV
WQAKGTWAHVLGTDKLGRDYLSRLLYGGQISLLIGLSAALISGLIGTTLGLCAGYFGGWVDSVVSYIVTTRLAMPVVLVA
LAMAALVGGSLKVVVLVLGFLLWDRFAVVTRAATQQIRNQDFVSAARAAGLTDLRIIRQEILPNIMNALIVVATLEMAHA
ILLEAALSFLGLGVQPPLPSWGLMIAEGKQYMFFQPWVITIPGVALLLLVLAINLLGDGLRDITAPEARN

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=295, Percent_Identity=42.3728813559322, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787054, Length=301, Percent_Identity=36.5448504983389, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1787760, Length=261, Percent_Identity=37.9310344827586, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=34.8360655737705, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787549, Length=289, Percent_Identity=33.2179930795848, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787498, Length=262, Percent_Identity=32.824427480916, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788505, Length=220, Percent_Identity=30, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32837; Mature: 32705

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCC
>Mature Secondary Structure 
SLPPDTAALAAPALPPDAPVALAPVPSPTRLVLRRGLRHTGFLIGAGILGLIVLAALAA
CCCCCCHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
PLIAPHDPYAQDVSRRLIPPVWQAKGTWAHVLGTDKLGRDYLSRLLYGGQISLLIGLSAA
HHCCCCCCHHHHHHHHCCCCHHHCCCCEEEHHCCHHCCHHHHHHHHHCCCHHHHHHHHHH
LISGLIGTTLGLCAGYFGGWVDSVVSYIVTTRLAMPVVLVALAMAALVGGSLKVVVLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FLLWDRFAVVTRAATQQIRNQDFVSAARAAGLTDLRIIRQEILPNIMNALIVVATLEMAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILLEAALSFLGLGVQPPLPSWGLMIAEGKQYMFFQPWVITIPGVALLLLVLAINLLGDG
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCC
LRDITAPEARN
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]