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The map label for this gene is coaE [H]

Identifier: 170750674

GI number: 170750674

Start: 4535255

End: 4535893

Strand: Reverse

Name: coaE [H]

Synonym: Mrad2831_4284

Alternate gene names: 170750674

Gene position: 4535893-4535255 (Counterclockwise)

Preceding gene: 170750675

Following gene: 170750673

Centisome position: 74.63

GC content: 76.53

Gene sequence:

>639_bases
ATGATGCCGACGGCCGGATCCGGACCCGTCATCCTCGGGCTCACGGGCTCGATCGGCATGGGCAAGTCGGCCACGGCCCG
GATGTTCGCGGAGCGCGGCGTCCCGGTCCACGACGCCGACGCCGCCGTCCACGCCCTCTACGGGCCGGGCGGCGCGGCCG
CGGCGGCGATCGGCGCGGCCTTTCCCGGCGTGCTCGGCGCGGACGGCGGCGTCGACCGGGCGCGGCTGCGCGCCGCGGTG
CTCGGTTCGCCGGACCGGATGGCGGCGCTGGAGGCCATCGTGCATCCCCTGGTCCGGGCGGCCAGCGCGGAATTCCTGGC
GCGGCACGCGGCGGCGGCGCTGGTCGTCCTCGACGTCCCGCTCCTCTACGAGACCGGCGGCGAGGACCGCTGCGACGCGG
TCGCGGTGGTGAGCGCCCCGCCCGAGATCCAGCGCGAACGGGTGCTCGCCCGACCCGGCATGACCGAGGCGGCCCTCGCG
GCGATCCTCGCCAAGCAGATGCCCGACGCCGAGAAGCGCGCCCGGGCGGATTTCGTCATCGACACGGGCCGGGGTTTCCC
CGCCGCCGAGGCCGAGGTGGCGCGGATCGTCGAGCGCCTGACAACGCCCCGTGCGAAGCCGCACGCCGGCAACGGATGA

Upstream 100 bases:

>100_bases
TGCTGCTGCACCAGGCGGTGCCGGGTTTCGAGGCGTGGTTCGGCCCGCGCCCCCGCGTCACCCCGGAGCTGCGCGACCGG
ATCGTGGCGGACCTCGCTGG

Downstream 100 bases:

>100_bases
CGTGCTGGGCGGATTGAATATCTGCGGTTGCGTTCCGGGGGGAACACGAACTGCGGGATGGACGTGATGGCGCGGCGCTG
GGGCGGGATCGATCGCGTTC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MMPTAGSGPVILGLTGSIGMGKSATARMFAERGVPVHDADAAVHALYGPGGAAAAAIGAAFPGVLGADGGVDRARLRAAV
LGSPDRMAALEAIVHPLVRAASAEFLARHAAAALVVLDVPLLYETGGEDRCDAVAVVSAPPEIQRERVLARPGMTEAALA
AILAKQMPDAEKRARADFVIDTGRGFPAAEAEVARIVERLTTPRAKPHAGNG

Sequences:

>Translated_212_residues
MMPTAGSGPVILGLTGSIGMGKSATARMFAERGVPVHDADAAVHALYGPGGAAAAAIGAAFPGVLGADGGVDRARLRAAV
LGSPDRMAALEAIVHPLVRAASAEFLARHAAAALVVLDVPLLYETGGEDRCDAVAVVSAPPEIQRERVLARPGMTEAALA
AILAKQMPDAEKRARADFVIDTGRGFPAAEAEVARIVERLTTPRAKPHAGNG
>Mature_212_residues
MMPTAGSGPVILGLTGSIGMGKSATARMFAERGVPVHDADAAVHALYGPGGAAAAAIGAAFPGVLGADGGVDRARLRAAV
LGSPDRMAALEAIVHPLVRAASAEFLARHAAAALVVLDVPLLYETGGEDRCDAVAVVSAPPEIQRERVLARPGMTEAALA
AILAKQMPDAEKRARADFVIDTGRGFPAAEAEVARIVERLTTPRAKPHAGNG

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI191252795, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI110227607, Length=175, Percent_Identity=29.7142857142857, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI110227605, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI110227603, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI110227601, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI205277394, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786292, Length=187, Percent_Identity=34.7593582887701, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=204, Percent_Identity=28.4313725490196, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25143409, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=199, Percent_Identity=28.643216080402, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24658602, Length=198, Percent_Identity=29.7979797979798, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644728, Length=205, Percent_Identity=28.780487804878, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21522; Mature: 21522

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPTAGSGPVILGLTGSIGMGKSATARMFAERGVPVHDADAAVHALYGPGGAAAAAIGAA
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHEEEEECCCHHHHHHHHHH
FPGVLGADGGVDRARLRAAVLGSPDRMAALEAIVHPLVRAASAEFLARHAAAALVVLDVP
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
LLYETGGEDRCDAVAVVSAPPEIQRERVLARPGMTEAALAAILAKQMPDAEKRARADFVI
HHEECCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHCCCEEE
DTGRGFPAAEAEVARIVERLTTPRAKPHAGNG
ECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMPTAGSGPVILGLTGSIGMGKSATARMFAERGVPVHDADAAVHALYGPGGAAAAAIGAA
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHEEEEECCCHHHHHHHHHH
FPGVLGADGGVDRARLRAAVLGSPDRMAALEAIVHPLVRAASAEFLARHAAAALVVLDVP
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
LLYETGGEDRCDAVAVVSAPPEIQRERVLARPGMTEAALAAILAKQMPDAEKRARADFVI
HHEECCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHCCCEEE
DTGRGFPAAEAEVARIVERLTTPRAKPHAGNG
ECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]