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The map label for this gene is ttuB [H]

Identifier: 170750640

GI number: 170750640

Start: 4496816

End: 4498138

Strand: Reverse

Name: ttuB [H]

Synonym: Mrad2831_4250

Alternate gene names: 170750640

Gene position: 4498138-4496816 (Counterclockwise)

Preceding gene: 170750641

Following gene: 170750639

Centisome position: 74.01

GC content: 70.9

Gene sequence:

>1323_bases
ATGACAGGCTCCTTGGACGAGGCCGCCCTGGAACGCTCGGCGATGCGCAGGATCGGCTGGCGGCTCGTGCCGTTCCTGAT
CCTCGCCTACTTCGTCTCCTTCCTGGACCGCGTGAATGTCGGCTTCGCGGCGATCCAGATGAACCACGATGTCGGCCTGT
CGGCGACCGTGTTCGGCTGGGGCGCCGGCATCTTCTTCCTCGGCTACTTCCTGATGGAGATCCCCAGCAACCTGATGCTG
GAGCGCTTCGGGGCGCGGCTGTGGATCGCCCGGATCATGGCGACCTGGGGGCTGATCTCCGCCGCCATGGCGCTGGTGCA
GGGGCCGTGGTCGTTCATCGGCCTGCGCTTCCTGCTGGGGCTCGCCGAGGCCGGCTTCTTCCCCGGCGTCATCCTCTACC
TCACCTACTGGTTCCCCTCCGCCTACCGGGCGCGGATCATCGGGATCTTCATGATCTCGATCCCGATCTCGTCGTTCCTC
GGCTCGCCGATCTCCGGCGCGCTGCTCAACGTGACGGGGCTCGGCCTCGCCGGCTGGCAGTGGCTGTTCATCCTCGAGGG
CCTGCCGGCGGTGTTCCTGGCCGTGGCGGTGCTGTGGTTCCTGCCGGACGGACCGCGGGACGCGGCGTGGCTGCCGGCGG
CCGAGCGGGACTGGCTGGAGCGGCAGCTCCGGGCCGAGGCGGCGCGCAACACCCGCCGCGGCCAGCCCGCGAAGCCGCCG
CTCTGGGACATCCTGCGCGACCGGCGGCTCGCCCTCTTCGCCGCCATCTACTTCGGCTCGACGGCGAGCAGCTACGGGCT
GTCGTTCTGGACGCCGCAGATCGTCAAGAGCTTCGGCCTCGGCAACGTCGAGACCGGGCTCCTGAACAGCATCCCGTACG
GGTTCGCGTCCCTCGCGATGGTCCTCTGGGGCCGGCACAGCGACCGGACCGCCGAGCGGCGCTGGCACCTCGCGCTCTCG
TTCCTGATCCTCGCGCTGGGGCTCGCGGGCGGCACGGTCCTCTCGGGGCTCGGCCCGGTCGTGGCGGCGCTGACGATCGC
CGCCATGGGCGTCTACATGCTCAAGGGCCCGTTCTGGGCGCTCGCGACCGAGCAGATGCCGCCCGCCACGGCGGCGGCGA
GCATCGCGGCCATCAACGCGGTCGGCAATCTCGGCGGCTTCCTCGGGCCCTACCTGATCGGCGCGATCAAGGACGGGACC
GGCAGCTTCACCTTGAGCCTTCTGCCCCTGGTGATCTTCGCCCTGCTCTCGGCCGCCCTGTCGCTGGTGCCGGGCCGCGC
CCCGCGTCCGGACCAGGGCACGCCGCGGCCGTCGACCGTCTGA

Upstream 100 bases:

>100_bases
CCCGCGCGGGCCCGGCCCTGACCCGGAGACGTGACCTGGATCGACCCGGACCCCCGCGGGGGCCGGCCTGACCCCGAGAC
ACGCCGCGAGGATAGGCCCG

Downstream 100 bases:

>100_bases
GCCCGGCCGGGCGGCGAACCGAGGCCGGGACCGGCCGGTTGGCTCCGGTACAGCCGTCGCCCGGCGCGGGGCCGATCCGG
ACCGGATCGGGGCCCGCGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTGSLDEAALERSAMRRIGWRLVPFLILAYFVSFLDRVNVGFAAIQMNHDVGLSATVFGWGAGIFFLGYFLMEIPSNLML
ERFGARLWIARIMATWGLISAAMALVQGPWSFIGLRFLLGLAEAGFFPGVILYLTYWFPSAYRARIIGIFMISIPISSFL
GSPISGALLNVTGLGLAGWQWLFILEGLPAVFLAVAVLWFLPDGPRDAAWLPAAERDWLERQLRAEAARNTRRGQPAKPP
LWDILRDRRLALFAAIYFGSTASSYGLSFWTPQIVKSFGLGNVETGLLNSIPYGFASLAMVLWGRHSDRTAERRWHLALS
FLILALGLAGGTVLSGLGPVVAALTIAAMGVYMLKGPFWALATEQMPPATAAASIAAINAVGNLGGFLGPYLIGAIKDGT
GSFTLSLLPLVIFALLSAALSLVPGRAPRPDQGTPRPSTV

Sequences:

>Translated_440_residues
MTGSLDEAALERSAMRRIGWRLVPFLILAYFVSFLDRVNVGFAAIQMNHDVGLSATVFGWGAGIFFLGYFLMEIPSNLML
ERFGARLWIARIMATWGLISAAMALVQGPWSFIGLRFLLGLAEAGFFPGVILYLTYWFPSAYRARIIGIFMISIPISSFL
GSPISGALLNVTGLGLAGWQWLFILEGLPAVFLAVAVLWFLPDGPRDAAWLPAAERDWLERQLRAEAARNTRRGQPAKPP
LWDILRDRRLALFAAIYFGSTASSYGLSFWTPQIVKSFGLGNVETGLLNSIPYGFASLAMVLWGRHSDRTAERRWHLALS
FLILALGLAGGTVLSGLGPVVAALTIAAMGVYMLKGPFWALATEQMPPATAAASIAAINAVGNLGGFLGPYLIGAIKDGT
GSFTLSLLPLVIFALLSAALSLVPGRAPRPDQGTPRPSTV
>Mature_439_residues
TGSLDEAALERSAMRRIGWRLVPFLILAYFVSFLDRVNVGFAAIQMNHDVGLSATVFGWGAGIFFLGYFLMEIPSNLMLE
RFGARLWIARIMATWGLISAAMALVQGPWSFIGLRFLLGLAEAGFFPGVILYLTYWFPSAYRARIIGIFMISIPISSFLG
SPISGALLNVTGLGLAGWQWLFILEGLPAVFLAVAVLWFLPDGPRDAAWLPAAERDWLERQLRAEAARNTRRGQPAKPPL
WDILRDRRLALFAAIYFGSTASSYGLSFWTPQIVKSFGLGNVETGLLNSIPYGFASLAMVLWGRHSDRTAERRWHLALSF
LILALGLAGGTVLSGLGPVVAALTIAAMGVYMLKGPFWALATEQMPPATAAASIAAINAVGNLGGFLGPYLIGAIKDGTG
SFTLSLLPLVIFALLSAALSLVPGRAPRPDQGTPRPSTV

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=381, Percent_Identity=22.3097112860892, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87082071, Length=393, Percent_Identity=38.4223918575064, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI2367379, Length=447, Percent_Identity=24.3847874720358, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082320, Length=384, Percent_Identity=23.4375, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789515, Length=451, Percent_Identity=24.1685144124169, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789152, Length=444, Percent_Identity=24.7747747747748, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367193, Length=302, Percent_Identity=25.4966887417219, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=352, Percent_Identity=23.8636363636364, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322025, Length=199, Percent_Identity=29.6482412060301, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6322612, Length=330, Percent_Identity=25.1515151515152, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323032, Length=294, Percent_Identity=25.1700680272109, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=266, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322973, Length=244, Percent_Identity=20.9016393442623, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=167, Percent_Identity=26.3473053892216, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641682, Length=382, Percent_Identity=24.869109947644, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.5955056179775, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584153, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47509; Mature: 47378

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSLDEAALERSAMRRIGWRLVPFLILAYFVSFLDRVNVGFAAIQMNHDVGLSATVFGW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHH
GAGIFFLGYFLMEIPSNLMLERFGARLWIARIMATWGLISAAMALVQGPWSFIGLRFLLG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LAEAGFFPGVILYLTYWFPSAYRARIIGIFMISIPISSFLGSPISGALLNVTGLGLAGWQ
HHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHH
WLFILEGLPAVFLAVAVLWFLPDGPRDAAWLPAAERDWLERQLRAEAARNTRRGQPAKPP
HHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
LWDILRDRRLALFAAIYFGSTASSYGLSFWTPQIVKSFGLGNVETGLLNSIPYGFASLAM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHCCHHHHHHHH
VLWGRHSDRTAERRWHLALSFLILALGLAGGTVLSGLGPVVAALTIAAMGVYMLKGPFWA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LATEQMPPATAAASIAAINAVGNLGGFLGPYLIGAIKDGTGSFTLSLLPLVIFALLSAAL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SLVPGRAPRPDQGTPRPSTV
HHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGSLDEAALERSAMRRIGWRLVPFLILAYFVSFLDRVNVGFAAIQMNHDVGLSATVFGW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHH
GAGIFFLGYFLMEIPSNLMLERFGARLWIARIMATWGLISAAMALVQGPWSFIGLRFLLG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LAEAGFFPGVILYLTYWFPSAYRARIIGIFMISIPISSFLGSPISGALLNVTGLGLAGWQ
HHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHH
WLFILEGLPAVFLAVAVLWFLPDGPRDAAWLPAAERDWLERQLRAEAARNTRRGQPAKPP
HHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
LWDILRDRRLALFAAIYFGSTASSYGLSFWTPQIVKSFGLGNVETGLLNSIPYGFASLAM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHCCHHHHHHHH
VLWGRHSDRTAERRWHLALSFLILALGLAGGTVLSGLGPVVAALTIAAMGVYMLKGPFWA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LATEQMPPATAAASIAAINAVGNLGGFLGPYLIGAIKDGTGSFTLSLLPLVIFALLSAAL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SLVPGRAPRPDQGTPRPSTV
HHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]