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The map label for this gene is 170750625

Identifier: 170750625

GI number: 170750625

Start: 4488432

End: 4489922

Strand: Reverse

Name: 170750625

Synonym: Mrad2831_4235

Alternate gene names: NA

Gene position: 4489922-4488432 (Counterclockwise)

Preceding gene: 170750626

Following gene: 170750624

Centisome position: 73.87

GC content: 71.03

Gene sequence:

>1491_bases
ATGAGCGAGGCCTGCATCTTCTCGGCCGGCTGCAGCGAACTCGCCGACCTCGTCCGGACCTACGACTGGGCGGAGACGCC
GCTCGGTCCCATCGCCGGCTGGCCGCGGAGCCTGGTCTTCGCGGTCAGCACGCTGCTGCAATCGCCGGTGCCGATCGTGC
TGCTCTGGGGCGAGGACGGCATCATGATCTACAACGATGCCTATTCGAGCTTCGCGGGCGGGCGCCATCCCGCGCTCCTC
GGCTCCAAGGTGCGCGAGGGCTGGCCGGAGGTCGCCGACTTCAACGACAACGTCATGCGCGTCGGCCTGGCCGGCGGGAC
GCTGTCGTACAAGGACCAGGAACTCACCCTGCACCGCTACGGCCGGCCCGAGCGGGTCTGGATGAATCTCGACTATTCGC
CGGTCTTCGGCGAGGACGGGCGCCCCGCCGGCGTCATCGCCATCGTGGTCGAGAGCACCGAGCGCGTGCTGGCCGAGCGC
CGCCTGCGCGCGAGCGAGGAGCTGTTCCGCACCCTCGCCCAGGGCATTCCGCAACTCGTCTGGCGCGCCGCGATCGACGG
AGCCTGCATCTGGTCGAGCCCGCAATGGCAGGCCTATACCGGGCAGACCGACGCGACGAGCCTCGGCTGGGGCTGGCTGG
AGGCGGTCCATCCGGGCGATGATGCGGTCGCCGAGGCCGCGTGGCGCGAGGCGCCGGTGAGCGGCCACCTCTCCTTCGAG
CACCGGCTCCGCAACGCGGCCGAGGACCGCTTCTGCTGGTTCCAGACCCGGGCCGCGCCGGTCCGCGACGCGCAGGGCCG
GATCGTCGAGTGGCTCGGCACCTCGACCGACATCGACGATCTGCGCCAGCTTCAGGAGCGGCAGCAGGTCATGGTCGCCG
AATTGCAGCACCGGACCCGCAACCTGCTCGGCGTCGTGCGCTCCATCGCCAAGCAGACGATGGCCCAGACCGGGCCCGGC
GAGACGTTCCGGCAGCGGTTCAACGACCGCCTGTCCGCCCTGTCCCGGGTTCAGGGCCTCCTCTCGCGCTCCGACCAGGA
GCCGATCACGCTCCGCTCCCTGATCGAGACGGAACTCGCCGCCCTCGATGCTCCGGCCATGCAGGCGCGCATCCGGCTCC
ACGGGCCGGTGGTGCGGCTGCGCAAGGCGACGGTGCAGACCTTCGCGCTGGCCCTGCACGAGCTCGCCACCAACGCGCTG
AAATACGGCGCGCTCACCACCGCGCACGGGCGCCTGAGCGTGACGTGGCGGACCTACAGGGCGGACGATGGCGGCGGCCG
GCTGCTGGTGGAATGGGTGGAGGAAGGCCTCGTCCGCGGACCGGAGCTGGCGGACGCGGTGCCGCGCGGCGGCTACGGGC
GGGAGCTGATCGAGCACGCCCTGCCCTACGCCCTGAAGGCGACGACCAGCTACGAACTCGGCGCAACGGCGCTACATTGC
TCGATCAACATCCCGCTCCCCGAGGGAGAAGCCACAGGCAGCCCCGCATGA

Upstream 100 bases:

>100_bases
GACCCGCCCGCCGGGACGGCCCACCCGGCCGGTCGCGGAACGGGCTTCCGCCATCCGCGCTGCGCTCGCCCGAGCTGGAG
CCTCACGAGTCGGTCACCGC

Downstream 100 bases:

>100_bases
CTCCGAAACCACGCGCGCTGGCCGGCAGGCGGGTCCTGCTGGTCGAGGACGATTACTTCATCGCCGTCGATCTCAAGTCC
GGCTTCGAGGAGGGCGGCGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSEACIFSAGCSELADLVRTYDWAETPLGPIAGWPRSLVFAVSTLLQSPVPIVLLWGEDGIMIYNDAYSSFAGGRHPALL
GSKVREGWPEVADFNDNVMRVGLAGGTLSYKDQELTLHRYGRPERVWMNLDYSPVFGEDGRPAGVIAIVVESTERVLAER
RLRASEELFRTLAQGIPQLVWRAAIDGACIWSSPQWQAYTGQTDATSLGWGWLEAVHPGDDAVAEAAWREAPVSGHLSFE
HRLRNAAEDRFCWFQTRAAPVRDAQGRIVEWLGTSTDIDDLRQLQERQQVMVAELQHRTRNLLGVVRSIAKQTMAQTGPG
ETFRQRFNDRLSALSRVQGLLSRSDQEPITLRSLIETELAALDAPAMQARIRLHGPVVRLRKATVQTFALALHELATNAL
KYGALTTAHGRLSVTWRTYRADDGGGRLLVEWVEEGLVRGPELADAVPRGGYGRELIEHALPYALKATTSYELGATALHC
SINIPLPEGEATGSPA

Sequences:

>Translated_496_residues
MSEACIFSAGCSELADLVRTYDWAETPLGPIAGWPRSLVFAVSTLLQSPVPIVLLWGEDGIMIYNDAYSSFAGGRHPALL
GSKVREGWPEVADFNDNVMRVGLAGGTLSYKDQELTLHRYGRPERVWMNLDYSPVFGEDGRPAGVIAIVVESTERVLAER
RLRASEELFRTLAQGIPQLVWRAAIDGACIWSSPQWQAYTGQTDATSLGWGWLEAVHPGDDAVAEAAWREAPVSGHLSFE
HRLRNAAEDRFCWFQTRAAPVRDAQGRIVEWLGTSTDIDDLRQLQERQQVMVAELQHRTRNLLGVVRSIAKQTMAQTGPG
ETFRQRFNDRLSALSRVQGLLSRSDQEPITLRSLIETELAALDAPAMQARIRLHGPVVRLRKATVQTFALALHELATNAL
KYGALTTAHGRLSVTWRTYRADDGGGRLLVEWVEEGLVRGPELADAVPRGGYGRELIEHALPYALKATTSYELGATALHC
SINIPLPEGEATGSPA
>Mature_495_residues
SEACIFSAGCSELADLVRTYDWAETPLGPIAGWPRSLVFAVSTLLQSPVPIVLLWGEDGIMIYNDAYSSFAGGRHPALLG
SKVREGWPEVADFNDNVMRVGLAGGTLSYKDQELTLHRYGRPERVWMNLDYSPVFGEDGRPAGVIAIVVESTERVLAERR
LRASEELFRTLAQGIPQLVWRAAIDGACIWSSPQWQAYTGQTDATSLGWGWLEAVHPGDDAVAEAAWREAPVSGHLSFEH
RLRNAAEDRFCWFQTRAAPVRDAQGRIVEWLGTSTDIDDLRQLQERQQVMVAELQHRTRNLLGVVRSIAKQTMAQTGPGE
TFRQRFNDRLSALSRVQGLLSRSDQEPITLRSLIETELAALDAPAMQARIRLHGPVVRLRKATVQTFALALHELATNALK
YGALTTAHGRLSVTWRTYRADDGGGRLLVEWVEEGLVRGPELADAVPRGGYGRELIEHALPYALKATTSYELGATALHCS
INIPLPEGEATGSPA

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54667; Mature: 54536

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEACIFSAGCSELADLVRTYDWAETPLGPIAGWPRSLVFAVSTLLQSPVPIVLLWGEDG
CCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
IMIYNDAYSSFAGGRHPALLGSKVREGWPEVADFNDNVMRVGLAGGTLSYKDQELTLHRY
EEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEHHHHC
GRPERVWMNLDYSPVFGEDGRPAGVIAIVVESTERVLAERRLRASEELFRTLAQGIPQLV
CCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRAAIDGACIWSSPQWQAYTGQTDATSLGWGWLEAVHPGDDAVAEAAWREAPVSGHLSFE
HHHHCCCCEEECCCCCCEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCHHH
HRLRNAAEDRFCWFQTRAAPVRDAQGRIVEWLGTSTDIDDLRQLQERQQVMVAELQHRTR
HHHHHHHHCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NLLGVVRSIAKQTMAQTGPGETFRQRFNDRLSALSRVQGLLSRSDQEPITLRSLIETELA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ALDAPAMQARIRLHGPVVRLRKATVQTFALALHELATNALKYGALTTAHGRLSVTWRTYR
HCCCHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEEEEE
ADDGGGRLLVEWVEEGLVRGPELADAVPRGGYGRELIEHALPYALKATTSYELGATALHC
CCCCCCEEHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHCCCEEECCCCCCCCCEEEEE
SINIPLPEGEATGSPA
EEECCCCCCCCCCCCC
>Mature Secondary Structure 
SEACIFSAGCSELADLVRTYDWAETPLGPIAGWPRSLVFAVSTLLQSPVPIVLLWGEDG
CCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
IMIYNDAYSSFAGGRHPALLGSKVREGWPEVADFNDNVMRVGLAGGTLSYKDQELTLHRY
EEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEHHHHC
GRPERVWMNLDYSPVFGEDGRPAGVIAIVVESTERVLAERRLRASEELFRTLAQGIPQLV
CCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRAAIDGACIWSSPQWQAYTGQTDATSLGWGWLEAVHPGDDAVAEAAWREAPVSGHLSFE
HHHHCCCCEEECCCCCCEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCHHH
HRLRNAAEDRFCWFQTRAAPVRDAQGRIVEWLGTSTDIDDLRQLQERQQVMVAELQHRTR
HHHHHHHHCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NLLGVVRSIAKQTMAQTGPGETFRQRFNDRLSALSRVQGLLSRSDQEPITLRSLIETELA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ALDAPAMQARIRLHGPVVRLRKATVQTFALALHELATNALKYGALTTAHGRLSVTWRTYR
HCCCHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEEEEE
ADDGGGRLLVEWVEEGLVRGPELADAVPRGGYGRELIEHALPYALKATTSYELGATALHC
CCCCCCEEHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHCCCEEECCCCCCCCCEEEEE
SINIPLPEGEATGSPA
EEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA