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The map label for this gene is kipR [H]

Identifier: 170750535

GI number: 170750535

Start: 4401310

End: 4402062

Strand: Direct

Name: kipR [H]

Synonym: Mrad2831_4142

Alternate gene names: 170750535

Gene position: 4401310-4402062 (Clockwise)

Preceding gene: 170750526

Following gene: 170750536

Centisome position: 72.42

GC content: 67.46

Gene sequence:

>753_bases
ATGGATCGCGTGTCCCGAATCCCGCGAAACCGGAACGAGTGCGAAGAGATGGCGAAGGAGGCGCGCGCGCGGCCCAATCT
CGAGGGCGTGGCTTCGGCCGATCGGGTTCTGACGGTGCTGACGGCGTTCCGGCGGGGCGACGACGCTCTGGAACTCTCCG
AGCTCGCGCGCCGCACGTCGCTCGTGAAGAGCACGATCATGCGGCTGTGCATCTCGCTGGAGAAGTTCGACCTGATCGAG
CGCCTGGACGACGGGCGCTATCGCCTCGGTGTCGAGGCGGCCCGGATCGGCTCGGTCTACCAGCAATCCTTCGCCCTGGA
GGAGCGGATCGTCCCGGTCCTGGAGCGGCTCGCCGCCGAGTCCTTCGAGACGGCCTCGTTCTACATCCGCCGGGGCAACC
AGCGGCTGTGCCTGTTCCGTGCCGACTCACCGTCACCGCTGCGGATGAACGTCCGCCCCGGCGACATGCGGCCGATGGAC
GAGTCCGCCATCGCGCAGGTTCTGAGGATTTTCGGCGACCGGAGGGCTACGGAAAGCTCGACGGCTCAGGTCCCCCTGTA
CTCGTCCGGTATCACCGACCCTCACGTCGCGTCGATCGCGATGCCCGTGTTCGGGACAGAGCAGCGGTTGATCGGTGCCA
TCGCTCTGTCCGGTCCAGCGTCTCGGTTGACCGCGGAGCGAGCCGAGACTCTCAAGCCGCGGCTCCGAGAGGCCGGCGAA
CGCCTCTCGTCTGAGCTCGGAGCACAGCTCTGA

Upstream 100 bases:

>100_bases
TTGAAACGGCGTTTCGTTTTTAATCCATCACGCGGCGGCGGTTGTCAACGATGTCGTGGAAGCGGCCCGTCACGGCTTGG
TGAGCGGTAGGCCGGTGGCT

Downstream 100 bases:

>100_bases
GTCAGTTCCCGGCTAACGGGCCGGCTCGACGAGCGGTGCTTCGCCGCTGCGGCGTACCTCATGATCGGTGCCCGCTCGTC
TGTCCCAGAGACCGTCGCGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MDRVSRIPRNRNECEEMAKEARARPNLEGVASADRVLTVLTAFRRGDDALELSELARRTSLVKSTIMRLCISLEKFDLIE
RLDDGRYRLGVEAARIGSVYQQSFALEERIVPVLERLAAESFETASFYIRRGNQRLCLFRADSPSPLRMNVRPGDMRPMD
ESAIAQVLRIFGDRRATESSTAQVPLYSSGITDPHVASIAMPVFGTEQRLIGAIALSGPASRLTAERAETLKPRLREAGE
RLSSELGAQL

Sequences:

>Translated_250_residues
MDRVSRIPRNRNECEEMAKEARARPNLEGVASADRVLTVLTAFRRGDDALELSELARRTSLVKSTIMRLCISLEKFDLIE
RLDDGRYRLGVEAARIGSVYQQSFALEERIVPVLERLAAESFETASFYIRRGNQRLCLFRADSPSPLRMNVRPGDMRPMD
ESAIAQVLRIFGDRRATESSTAQVPLYSSGITDPHVASIAMPVFGTEQRLIGAIALSGPASRLTAERAETLKPRLREAGE
RLSSELGAQL
>Mature_250_residues
MDRVSRIPRNRNECEEMAKEARARPNLEGVASADRVLTVLTAFRRGDDALELSELARRTSLVKSTIMRLCISLEKFDLIE
RLDDGRYRLGVEAARIGSVYQQSFALEERIVPVLERLAAESFETASFYIRRGNQRLCLFRADSPSPLRMNVRPGDMRPMD
ESAIAQVLRIFGDRRATESSTAQVPLYSSGITDPHVASIAMPVFGTEQRLIGAIALSGPASRLTAERAETLKPRLREAGE
RLSSELGAQL

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27864; Mature: 27864

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVSRIPRNRNECEEMAKEARARPNLEGVASADRVLTVLTAFRRGDDALELSELARRTS
CCCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVKSTIMRLCISLEKFDLIERLDDGRYRLGVEAARIGSVYQQSFALEERIVPVLERLAAE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFETASFYIRRGNQRLCLFRADSPSPLRMNVRPGDMRPMDESAIAQVLRIFGDRRATESS
HHHHHHHHEECCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
TAQVPLYSSGITDPHVASIAMPVFGTEQRLIGAIALSGPASRLTAERAETLKPRLREAGE
CCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RLSSELGAQL
HHHHHHCCCC
>Mature Secondary Structure
MDRVSRIPRNRNECEEMAKEARARPNLEGVASADRVLTVLTAFRRGDDALELSELARRTS
CCCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVKSTIMRLCISLEKFDLIERLDDGRYRLGVEAARIGSVYQQSFALEERIVPVLERLAAE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFETASFYIRRGNQRLCLFRADSPSPLRMNVRPGDMRPMDESAIAQVLRIFGDRRATESS
HHHHHHHHEECCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
TAQVPLYSSGITDPHVASIAMPVFGTEQRLIGAIALSGPASRLTAERAETLKPRLREAGE
CCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RLSSELGAQL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]