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The map label for this gene is engD [H]

Identifier: 170750517

GI number: 170750517

Start: 4378576

End: 4379673

Strand: Reverse

Name: engD [H]

Synonym: Mrad2831_4124

Alternate gene names: 170750517

Gene position: 4379673-4378576 (Counterclockwise)

Preceding gene: 170750518

Following gene: 170750516

Centisome position: 72.06

GC content: 69.4

Gene sequence:

>1098_bases
ATGGGCTTCAAATGCGGCATCGTCGGCCTGCCGAACGTCGGCAAGTCGACCCTCTTCAACGCGCTGACGCAGACGGCGGC
CGCCCAGGCGGCGAACTACCCGTTCTGCACCATCGAGCCGAATGTCGGCGAGGTGGCGGTGCCGGATCCGCGGCTGACTG
ACCTCGCCCGGATCGCGTCCTCGAAGGAGATCATCCCGACGCGGCTGACCTTCGTGGACATCGCCGGCCTCGTCCGCGGC
GCCTCCAAGGGCGAGGGCCTGGGCAACCAGTTCCTGGCCAATATCCGCGAGGTCGACGCCATCGCCCACGTGGTCCGCTG
CTTCACGGACGGCGACGTCACCCACGTGGAGGGCAAGGTCGATCCGGCCGCCGATATCGAGACCATCGAGACCGAGCTGA
TGCTCGCCGACCTCGACAGCCTGGAGCGCCGCGCCCAGTCGCTGGAGAAGAAGGCCAAGGGCGCCGACAAGGAGGCCAAG
GAGACCCTCGACCTCGTCAACCGCGCCCTGCCGCTCCTGCGCGACGGCAAGCCCGCCCGCCTCGTGGAGCGCAAGCCCGA
CGAGGAGAGGCTGTTCCAGCAGCTCGGCCTGATGACCGCCAAGCCCGTCCTCTACGTCTGCAACGTCGACGAGGGCGACG
CCGACAAGGGCAACGCCTACTCGGACGCGGTCTTCGCCCGCGCCAGGGCGGAGGGCGCCGTGGCGGTGGTGGTCTCGGCC
AAGATCGAGAGCGAGATCGCCGTGATGCCGGAGGCCGACCAGGCCGAGTTCCTGGAGGCGGTGGGGCTCACCGAGCCGGG
CCTGAACCGGGTGATCCGCGCCGGCTACGACCTGCTCGGCCTCGTCACCTACTTCACGGTCGGCCCCAAGGAGGCCCGCG
CCTGGACGATCACCAAGGGCACCCGCGCCCCCGGGGCGGCCGGGGTGATCCACTCGGATTTCGAGAAGGGCTTCATCCGC
GCCGAGACGATCGCGTTCAAGGATTACACGACCCTCAACGGCGAGGCCGGGGCCCGGGACGCCGGCAAGCTCCGGCTGGA
GGGCAAGGATTACGTGGTGCAGGACGGCGACGTGCTGCACTTCCGCTTCGCCAACTGA

Upstream 100 bases:

>100_bases
GTGCTCGACCGAGGACAGGGCGCGCGGCGTGTTCGCGGACCCGATTCTCATCAACCCATTCCGCGCGTCGCCCGACGACG
CGCTGCGACGGAACTGACCC

Downstream 100 bases:

>100_bases
GGCCGGTGCTGTCGGCACGGTGCGCGCGCTTCATCCCCGCCCCGCTGATCAACGAGACGAGCCCGCCATGCCCGATCCCG
CCCTCGAAGACTTCTCCGTC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPDPRLTDLARIASSKEIIPTRLTFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIAHVVRCFTDGDVTHVEGKVDPAADIETIETELMLADLDSLERRAQSLEKKAKGADKEAK
ETLDLVNRALPLLRDGKPARLVERKPDEERLFQQLGLMTAKPVLYVCNVDEGDADKGNAYSDAVFARARAEGAVAVVVSA
KIESEIAVMPEADQAEFLEAVGLTEPGLNRVIRAGYDLLGLVTYFTVGPKEARAWTITKGTRAPGAAGVIHSDFEKGFIR
AETIAFKDYTTLNGEAGARDAGKLRLEGKDYVVQDGDVLHFRFAN

Sequences:

>Translated_365_residues
MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPDPRLTDLARIASSKEIIPTRLTFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIAHVVRCFTDGDVTHVEGKVDPAADIETIETELMLADLDSLERRAQSLEKKAKGADKEAK
ETLDLVNRALPLLRDGKPARLVERKPDEERLFQQLGLMTAKPVLYVCNVDEGDADKGNAYSDAVFARARAEGAVAVVVSA
KIESEIAVMPEADQAEFLEAVGLTEPGLNRVIRAGYDLLGLVTYFTVGPKEARAWTITKGTRAPGAAGVIHSDFEKGFIR
AETIAFKDYTTLNGEAGARDAGKLRLEGKDYVVQDGDVLHFRFAN
>Mature_364_residues
GFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPDPRLTDLARIASSKEIIPTRLTFVDIAGLVRGA
SKGEGLGNQFLANIREVDAIAHVVRCFTDGDVTHVEGKVDPAADIETIETELMLADLDSLERRAQSLEKKAKGADKEAKE
TLDLVNRALPLLRDGKPARLVERKPDEERLFQQLGLMTAKPVLYVCNVDEGDADKGNAYSDAVFARARAEGAVAVVVSAK
IESEIAVMPEADQAEFLEAVGLTEPGLNRVIRAGYDLLGLVTYFTVGPKEARAWTITKGTRAPGAAGVIHSDFEKGFIRA
ETIAFKDYTTLNGEAGARDAGKLRLEGKDYVVQDGDVLHFRFAN

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=367, Percent_Identity=42.7792915531335, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI58761502, Length=231, Percent_Identity=35.0649350649351, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=58.4022038567493, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=148, Percent_Identity=29.7297297297297, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.896174863388, Blast_Score=280, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=40.2702702702703, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=35.6955380577428, Blast_Score=226, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=356, Percent_Identity=30.3370786516854, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=42.2343324250681, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=42.2343324250681, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=42.2343324250681, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24640879, Length=324, Percent_Identity=39.5061728395062, Blast_Score=224, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24585318, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39259; Mature: 39128

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPDPRLTDLARIAS
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCHHHHHHHHC
SKEIIPTRLTFVDIAGLVRGASKGEGLGNQFLANIREVDAIAHVVRCFTDGDVTHVEGKV
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DPAADIETIETELMLADLDSLERRAQSLEKKAKGADKEAKETLDLVNRALPLLRDGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCH
LVERKPDEERLFQQLGLMTAKPVLYVCNVDEGDADKGNAYSDAVFARARAEGAVAVVVSA
HHCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
KIESEIAVMPEADQAEFLEAVGLTEPGLNRVIRAGYDLLGLVTYFTVGPKEARAWTITKG
ECCCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEECC
TRAPGAAGVIHSDFEKGFIRAETIAFKDYTTLNGEAGARDAGKLRLEGKDYVVQDGDVLH
CCCCCCCCCCHHHHHHCCEEEEEEEEECCEEECCCCCCCCCCEEEECCCCEEEECCCEEE
FRFAN
EEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPDPRLTDLARIAS
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCHHHHHHHHC
SKEIIPTRLTFVDIAGLVRGASKGEGLGNQFLANIREVDAIAHVVRCFTDGDVTHVEGKV
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DPAADIETIETELMLADLDSLERRAQSLEKKAKGADKEAKETLDLVNRALPLLRDGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCH
LVERKPDEERLFQQLGLMTAKPVLYVCNVDEGDADKGNAYSDAVFARARAEGAVAVVVSA
HHCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
KIESEIAVMPEADQAEFLEAVGLTEPGLNRVIRAGYDLLGLVTYFTVGPKEARAWTITKG
ECCCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEECC
TRAPGAAGVIHSDFEKGFIRAETIAFKDYTTLNGEAGARDAGKLRLEGKDYVVQDGDVLH
CCCCCCCCCCHHHHHHCCEEEEEEEEECCEEECCCCCCCCCCEEEECCCCEEEECCCEEE
FRFAN
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA