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The map label for this gene is mtnA [H]

Identifier: 170750514

GI number: 170750514

Start: 4375472

End: 4376575

Strand: Direct

Name: mtnA [H]

Synonym: Mrad2831_4121

Alternate gene names: 170750514

Gene position: 4375472-4376575 (Clockwise)

Preceding gene: 170750507

Following gene: 170750515

Centisome position: 71.99

GC content: 73.55

Gene sequence:

>1104_bases
ATGAATATCGACGGCCAGCCCTACCGCACGATCTTCCCGGACCCCGACGGCGTCAGCGTCCAGGTCATCGACCAGACCCG
CCTGCCCTTCGCGTTCGAGTTGAGGCGCCTCGCCACGCTGGAGGACGCCGCGGTGGCGATCCGCACGATGATCGTGCGGG
GCGCGCCCCTGATCGGCGTCACGGCCGCCTACGGGCTGGCGCTCGCCATGCGGGCCGACGCCTCCCACGACGGCATCGAC
CGGGCGGTGGCGACGCTCGCGGCGACCCGCCCGACCGCGATCAACCTGCGCTGGGCGCTGGACCGGGTCTCCGCCAACCT
GCGCCAGACCGCGCCGGACGAGCGCTTCGCCCGCGCCTTCGCGGAGGCCGGCCGCATCGCCGAGGAGGACGTGGCGAGCT
GCCGCGCGATCGGCGCCCACGGCGGCCAGATCATCGCCGACCTCCACGCGGCCCGGGGCGGCGACCGGCCGATCACCGTG
CTGACCCACTGCAATGCCGGCTGGCTGGCCACGGTGGACTGGGGCACGGCGCTCGCGCCGGTCTACGCCGCCCACGAGCG
GGGCGTGCCGGTCCACGTCTTGGTCGACGAGACCCGGCCGCGCAGCCAGGGCGCCGCGCTCACGGCCTTCGAGCTGAACG
GCCACGGCGTGCCGCACACGGTCATCGCCGACAATGCCGGCGGCCACCTGATGCAGCACGGCGACGTCGACCTCTGCATC
GTCGGCTCGGACCGGACCACGGCGAGCGGCGACGTCTGCAACAAGATCGGCACCTACCTGAAGGCGCTGGCGGCCCACGA
CAACGGCGTGCCGTTCTACGCCGCCCTGCCGTTCTCGACCATCGACTGGACGCTCGACGACGGGGTGAAGGAGATCCCGA
TCGAGGAGCGCGACGGGCGCGAGGTCACCCACATGACCGGCCGGCTGCCCGACGGCGGCTTCGCCACGATCGAGGTCGTC
TCCCCCGGCAGCCCGGTGGCCAACCCCGCCTTCGACGTGACGCCGTCGCGCCTCGTGACCGGGATCATCACGGAGCGCGG
CATCTGCGACGCGAGCCGCGAGGGCCTGTACGGGCTCTACCCGGAGCGCCGGAGCGCGGCGTGA

Upstream 100 bases:

>100_bases
TTGAGGAAGGCTGACCGGCCGCCGGGCGGGGCATCCCCAGGCCGTCGCGCCGGCGCCCGGGAGGATGCAAAAGCCGCCTC
GCTGTGGCACAGGAGCGGCC

Downstream 100 bases:

>100_bases
GGGCGGAGTTCCGGGCGGCCGCGGCCGCCCGGCGCAGTATCCGGGGCGTCCCGAACGCGGTGTGACCGAAAAGGCAGCCT
CGGGGGCAATTCGCGCCCCG

Product: aIF-2BI family translation initiation factor

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNIDGQPYRTIFPDPDGVSVQVIDQTRLPFAFELRRLATLEDAAVAIRTMIVRGAPLIGVTAAYGLALAMRADASHDGID
RAVATLAATRPTAINLRWALDRVSANLRQTAPDERFARAFAEAGRIAEEDVASCRAIGAHGGQIIADLHAARGGDRPITV
LTHCNAGWLATVDWGTALAPVYAAHERGVPVHVLVDETRPRSQGAALTAFELNGHGVPHTVIADNAGGHLMQHGDVDLCI
VGSDRTTASGDVCNKIGTYLKALAAHDNGVPFYAALPFSTIDWTLDDGVKEIPIEERDGREVTHMTGRLPDGGFATIEVV
SPGSPVANPAFDVTPSRLVTGIITERGICDASREGLYGLYPERRSAA

Sequences:

>Translated_367_residues
MNIDGQPYRTIFPDPDGVSVQVIDQTRLPFAFELRRLATLEDAAVAIRTMIVRGAPLIGVTAAYGLALAMRADASHDGID
RAVATLAATRPTAINLRWALDRVSANLRQTAPDERFARAFAEAGRIAEEDVASCRAIGAHGGQIIADLHAARGGDRPITV
LTHCNAGWLATVDWGTALAPVYAAHERGVPVHVLVDETRPRSQGAALTAFELNGHGVPHTVIADNAGGHLMQHGDVDLCI
VGSDRTTASGDVCNKIGTYLKALAAHDNGVPFYAALPFSTIDWTLDDGVKEIPIEERDGREVTHMTGRLPDGGFATIEVV
SPGSPVANPAFDVTPSRLVTGIITERGICDASREGLYGLYPERRSAA
>Mature_367_residues
MNIDGQPYRTIFPDPDGVSVQVIDQTRLPFAFELRRLATLEDAAVAIRTMIVRGAPLIGVTAAYGLALAMRADASHDGID
RAVATLAATRPTAINLRWALDRVSANLRQTAPDERFARAFAEAGRIAEEDVASCRAIGAHGGQIIADLHAARGGDRPITV
LTHCNAGWLATVDWGTALAPVYAAHERGVPVHVLVDETRPRSQGAALTAFELNGHGVPHTVIADNAGGHLMQHGDVDLCI
VGSDRTTASGDVCNKIGTYLKALAAHDNGVPFYAALPFSTIDWTLDDGVKEIPIEERDGREVTHMTGRLPDGGFATIEVV
SPGSPVANPAFDVTPSRLVTGIITERGICDASREGLYGLYPERRSAA

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=344, Percent_Identity=40.406976744186, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI23943880, Length=338, Percent_Identity=34.9112426035503, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17557462, Length=336, Percent_Identity=33.9285714285714, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6325375, Length=397, Percent_Identity=27.7078085642317, Blast_Score=162, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21357667, Length=348, Percent_Identity=37.3563218390805, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24651647, Length=348, Percent_Identity=37.3563218390805, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38988; Mature: 38988

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDGQPYRTIFPDPDGVSVQVIDQTRLPFAFELRRLATLEDAAVAIRTMIVRGAPLIGV
CCCCCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
TAAYGLALAMRADASHDGIDRAVATLAATRPTAINLRWALDRVSANLRQTAPDERFARAF
HHHHHEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCHHHHHHHH
AEAGRIAEEDVASCRAIGAHGGQIIADLHAARGGDRPITVLTHCNAGWLATVDWGTALAP
HHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCEEEEEECCCCEEEEECCCCHHHH
VYAAHERGVPVHVLVDETRPRSQGAALTAFELNGHGVPHTVIADNAGGHLMQHGDVDLCI
HHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCEEECCCEEEEE
VGSDRTTASGDVCNKIGTYLKALAAHDNGVPFYAALPFSTIDWTLDDGVKEIPIEERDGR
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCC
EVTHMTGRLPDGGFATIEVVSPGSPVANPAFDVTPSRLVTGIITERGICDASREGLYGLY
EEEHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEECC
PERRSAA
CCCCCCC
>Mature Secondary Structure
MNIDGQPYRTIFPDPDGVSVQVIDQTRLPFAFELRRLATLEDAAVAIRTMIVRGAPLIGV
CCCCCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
TAAYGLALAMRADASHDGIDRAVATLAATRPTAINLRWALDRVSANLRQTAPDERFARAF
HHHHHEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCHHHHHHHH
AEAGRIAEEDVASCRAIGAHGGQIIADLHAARGGDRPITVLTHCNAGWLATVDWGTALAP
HHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCEEEEEECCCCEEEEECCCCHHHH
VYAAHERGVPVHVLVDETRPRSQGAALTAFELNGHGVPHTVIADNAGGHLMQHGDVDLCI
HHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCEEECCCEEEEE
VGSDRTTASGDVCNKIGTYLKALAAHDNGVPFYAALPFSTIDWTLDDGVKEIPIEERDGR
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCC
EVTHMTGRLPDGGFATIEVVSPGSPVANPAFDVTPSRLVTGIITERGICDASREGLYGLY
EEEHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEECC
PERRSAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA