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The map label for this gene is ribD [H]

Identifier: 170750355

GI number: 170750355

Start: 4210866

End: 4211975

Strand: Direct

Name: ribD [H]

Synonym: Mrad2831_3958

Alternate gene names: 170750355

Gene position: 4210866-4211975 (Clockwise)

Preceding gene: 170750354

Following gene: 170750356

Centisome position: 69.28

GC content: 78.92

Gene sequence:

>1110_bases
ATGAGCGGCGACGCGAACTTCATGCGCCTCGCCCTGGCGCTGGGCCGCCGCGGGCTCGGCACCACCTGGCCGAACCCGTC
GGTCGGCGCCGTCGTGGTCGAGCCCGGGACCGGCCGGATCCTCGGGACGGCGGCCACGGCGCAGGGCGGGCGCCCGCACG
GGGAGCCCGTGGCGCTCGCCGCCGCCGGAGAGGCCGCCCGCGGCGCGACCCTCTACGTCACCCTGGAGCCCTGCTCCCAT
CACGGCCGCACGCCACCCTGCACCGACGCGATCCTGGCCGCCGGGATCGCCCGGGTGGTCAGCGCCCTGGAGGATCCCGA
CCCGCGGGTGGCGGGGCGCGGCCACGACCTCCTGCGGCGGGGCGGCGTCGCGGTCGAGACCGGCCTGATGCGGGACGAGG
CGGCGCGCGACCATGTCGGCCACGTCACCCGGGTGACGCGCGGCCGCCCGGCCCTGCACCTCAAGCTCGCCCGCACCCGG
GACGGCTTCTGCGCCGCCGCGGGGCCGGAGCGCCTGCGGATCACCGGGCCGGTGGCGGACGGGGCGGTCCACCTCTGGCG
GGCCCACGCCGACGCGATCCTGATCGGCATCGGCACCGCCCGGGCCGACGACCCGTCGCTGACGGTGCGGCTACCGGGCC
TAGGGGCGCGCTCGCCCCTGCGGGTCGTGCTCGATACGCACCTGCGGCTCTCCCCCGCGAGCGTGCTCGCCCGGACCGCC
CGCGACACGCCGACCCTGGTGCTCACGACCCGCTCGGCGCCGGCCCACGCGCGGCGGGCCCTGGAGGCGCTCGGCGTCGC
GGTCGCGACCGTGCCGGCGGACCCGGCCGGCGGGATCGATCTGCCGGCGGCCCTGACGCATCTCGGCGAGCGCGGCCTGA
CCCGCCTGTGCAGCGAGGGCGGCCCCCGCCTTGCGGAGGCGCTCGCGCGGGCCGATCTGATCGATGCCTGCACGCTCGTC
ACCGGGCCGATGGCGCTGGGACCGGCGGGCGGGCTGCGGGCCCTGGGCCCGGCCCTGGCGGAGGCCCTTTCGGGCGATCG
GTTCCGCGAGGCCGAGCGGCTGCAGCTCGGGCCCGACGCGGCCGTGACCTACGAGCGCAACAGGACGTAA

Upstream 100 bases:

>100_bases
TCGGCACCCTGAGCGACGGCATGCCGGTGCCGGCGGCCGCGCCGGAGGCGGAGGGCGACCCGGAACCCGAGGCGTCGGGG
CGCCGCCGCGCCGGGCGTCC

Downstream 100 bases:

>100_bases
GCGATGTTCACCGGCTTGGTCAGCGATGTCGGCACGGTCGCCTCGGTCTCGGGCGACGGCGACCTGCTTCGGATCGCGAT
CCGCGCCTCCTACGACCCGG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSGDANFMRLALALGRRGLGTTWPNPSVGAVVVEPGTGRILGTAATAQGGRPHGEPVALAAAGEAARGATLYVTLEPCSH
HGRTPPCTDAILAAGIARVVSALEDPDPRVAGRGHDLLRRGGVAVETGLMRDEAARDHVGHVTRVTRGRPALHLKLARTR
DGFCAAAGPERLRITGPVADGAVHLWRAHADAILIGIGTARADDPSLTVRLPGLGARSPLRVVLDTHLRLSPASVLARTA
RDTPTLVLTTRSAPAHARRALEALGVAVATVPADPAGGIDLPAALTHLGERGLTRLCSEGGPRLAEALARADLIDACTLV
TGPMALGPAGGLRALGPALAEALSGDRFREAERLQLGPDAAVTYERNRT

Sequences:

>Translated_369_residues
MSGDANFMRLALALGRRGLGTTWPNPSVGAVVVEPGTGRILGTAATAQGGRPHGEPVALAAAGEAARGATLYVTLEPCSH
HGRTPPCTDAILAAGIARVVSALEDPDPRVAGRGHDLLRRGGVAVETGLMRDEAARDHVGHVTRVTRGRPALHLKLARTR
DGFCAAAGPERLRITGPVADGAVHLWRAHADAILIGIGTARADDPSLTVRLPGLGARSPLRVVLDTHLRLSPASVLARTA
RDTPTLVLTTRSAPAHARRALEALGVAVATVPADPAGGIDLPAALTHLGERGLTRLCSEGGPRLAEALARADLIDACTLV
TGPMALGPAGGLRALGPALAEALSGDRFREAERLQLGPDAAVTYERNRT
>Mature_368_residues
SGDANFMRLALALGRRGLGTTWPNPSVGAVVVEPGTGRILGTAATAQGGRPHGEPVALAAAGEAARGATLYVTLEPCSHH
GRTPPCTDAILAAGIARVVSALEDPDPRVAGRGHDLLRRGGVAVETGLMRDEAARDHVGHVTRVTRGRPALHLKLARTRD
GFCAAAGPERLRITGPVADGAVHLWRAHADAILIGIGTARADDPSLTVRLPGLGARSPLRVVLDTHLRLSPASVLARTAR
DTPTLVLTTRSAPAHARRALEALGVAVATVPADPAGGIDLPAALTHLGERGLTRLCSEGGPRLAEALARADLIDACTLVT
GPMALGPAGGLRALGPALAEALSGDRFREAERLQLGPDAAVTYERNRT

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=380, Percent_Identity=39.7368421052632, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 37985; Mature: 37854

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDANFMRLALALGRRGLGTTWPNPSVGAVVVEPGTGRILGTAATAQGGRPHGEPVALA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCEEEE
AAGEAARGATLYVTLEPCSHHGRTPPCTDAILAAGIARVVSALEDPDPRVAGRGHDLLRR
ECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GGVAVETGLMRDEAARDHVGHVTRVTRGRPALHLKLARTRDGFCAAAGPERLRITGPVAD
CCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCEEEEECCCCC
GAVHLWRAHADAILIGIGTARADDPSLTVRLPGLGARSPLRVVLDTHLRLSPASVLARTA
CHHHEEHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHC
RDTPTLVLTTRSAPAHARRALEALGVAVATVPADPAGGIDLPAALTHLGERGLTRLCSEG
CCCCEEEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GPRLAEALARADLIDACTLVTGPMALGPAGGLRALGPALAEALSGDRFREAERLQLGPDA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
AVTYERNRT
EEEECCCCC
>Mature Secondary Structure 
SGDANFMRLALALGRRGLGTTWPNPSVGAVVVEPGTGRILGTAATAQGGRPHGEPVALA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCEEEE
AAGEAARGATLYVTLEPCSHHGRTPPCTDAILAAGIARVVSALEDPDPRVAGRGHDLLRR
ECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GGVAVETGLMRDEAARDHVGHVTRVTRGRPALHLKLARTRDGFCAAAGPERLRITGPVAD
CCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCEEEEECCCCC
GAVHLWRAHADAILIGIGTARADDPSLTVRLPGLGARSPLRVVLDTHLRLSPASVLARTA
CHHHEEHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHC
RDTPTLVLTTRSAPAHARRALEALGVAVATVPADPAGGIDLPAALTHLGERGLTRLCSEG
CCCCEEEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GPRLAEALARADLIDACTLVTGPMALGPAGGLRALGPALAEALSGDRFREAERLQLGPDA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
AVTYERNRT
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]