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The map label for this gene is ribE [H]

Identifier: 170750356

GI number: 170750356

Start: 4211979

End: 4212602

Strand: Direct

Name: ribE [H]

Synonym: Mrad2831_3959

Alternate gene names: 170750356

Gene position: 4211979-4212602 (Clockwise)

Preceding gene: 170750355

Following gene: 170750369

Centisome position: 69.3

GC content: 73.08

Gene sequence:

>624_bases
ATGTTCACCGGCTTGGTCAGCGATGTCGGCACGGTCGCCTCGGTCTCGGGCGACGGCGACCTGCTTCGGATCGCGATCCG
CGCCTCCTACGACCCGGCGACGATCGCGCTCGGCGCCTCGATCGCCTGCGCCGGGCCGTGCCTGACCGCCGTGTCGGTGG
AGCCGACCGCGGGCGGCTGCGTCTTCGCGGTCGACGCCGCCGCCGAGACGCTGGCGCGCACCACCGTGGGCGCCTGGGTG
GCGGGCACGCGGATCAACCTCGAACGCTCCCTGAAGATCGGCGACGAGCTCGGCGGGCACCTCGTCACCGGCCACGTCGA
CGGCGTCGCCGAGATCGTGGAACGCGAGACCGTCACGGCCGATGCCTGGGGCGCCAGCGAGCGGTTCACCCTCCGGGCGC
CGGCGGCCCTGGCGAAGTTCATCGCCGAGAAGGGCTCGGTCTGCCTCGACGGCACCTCGCTCACGGTGAACGCGGTCCAG
GGCGACCTGTTCTCGGTGCTGCTGATCCCGCACACGCTCCAGGTCACTACCTGGGGCGAGCGGCGGCAGGGTGACCGGCT
CAACCTGGAGGTCGACCTGATCGCCCGCTACGCCGCCCGGCTGACCGAGGCGCGGGCCGGCTGA

Upstream 100 bases:

>100_bases
CCTGGCGGAGGCCCTTTCGGGCGATCGGTTCCGCGAGGCCGAGCGGCTGCAGCTCGGGCCCGACGCGGCCGTGACCTACG
AGCGCAACAGGACGTAAGCG

Downstream 100 bases:

>100_bases
GCAGGGTACGCGTCTTCGCCAGCGGAGCGAAGCAGACCCACAGCGCCACATCGCCGGGCGTCGCGCGGCCCTGAGTTGCC
TCGCTCCGCCCGCAGCGACG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFTGLVSDVGTVASVSGDGDLLRIAIRASYDPATIALGASIACAGPCLTAVSVEPTAGGCVFAVDAAAETLARTTVGAWV
AGTRINLERSLKIGDELGGHLVTGHVDGVAEIVERETVTADAWGASERFTLRAPAALAKFIAEKGSVCLDGTSLTVNAVQ
GDLFSVLLIPHTLQVTTWGERRQGDRLNLEVDLIARYAARLTEARAG

Sequences:

>Translated_207_residues
MFTGLVSDVGTVASVSGDGDLLRIAIRASYDPATIALGASIACAGPCLTAVSVEPTAGGCVFAVDAAAETLARTTVGAWV
AGTRINLERSLKIGDELGGHLVTGHVDGVAEIVERETVTADAWGASERFTLRAPAALAKFIAEKGSVCLDGTSLTVNAVQ
GDLFSVLLIPHTLQVTTWGERRQGDRLNLEVDLIARYAARLTEARAG
>Mature_207_residues
MFTGLVSDVGTVASVSGDGDLLRIAIRASYDPATIALGASIACAGPCLTAVSVEPTAGGCVFAVDAAAETLARTTVGAWV
AGTRINLERSLKIGDELGGHLVTGHVDGVAEIVERETVTADAWGASERFTLRAPAALAKFIAEKGSVCLDGTSLTVNAVQ
GDLFSVLLIPHTLQVTTWGERRQGDRLNLEVDLIARYAARLTEARAG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=196, Percent_Identity=35.2040816326531, Blast_Score=98, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319733, Length=213, Percent_Identity=37.0892018779343, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21420; Mature: 21420

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLVSDVGTVASVSGDGDLLRIAIRASYDPATIALGASIACAGPCLTAVSVEPTAGGC
CCCCHHHCCCCEEEECCCCCEEEEEEEECCCCEEEEECCCEEECCCCEEEEEECCCCCCE
VFAVDAAAETLARTTVGAWVAGTRINLERSLKIGDELGGHLVTGHVDGVAEIVERETVTA
EEEEHHHHHHHHHHHHHHEEECEEEEEEECEECCCCCCCEEEEECHHHHHHHHHHCCEEE
DAWGASERFTLRAPAALAKFIAEKGSVCLDGTSLTVNAVQGDLFSVLLIPHTLQVTTWGE
CCCCCCCEEEEECHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEEEECCEEEEEECCC
RRQGDRLNLEVDLIARYAARLTEARAG
CCCCCEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGLVSDVGTVASVSGDGDLLRIAIRASYDPATIALGASIACAGPCLTAVSVEPTAGGC
CCCCHHHCCCCEEEECCCCCEEEEEEEECCCCEEEEECCCEEECCCCEEEEEECCCCCCE
VFAVDAAAETLARTTVGAWVAGTRINLERSLKIGDELGGHLVTGHVDGVAEIVERETVTA
EEEEHHHHHHHHHHHHHHEEECEEEEEEECEECCCCCCCEEEEECHHHHHHHHHHCCEEE
DAWGASERFTLRAPAALAKFIAEKGSVCLDGTSLTVNAVQGDLFSVLLIPHTLQVTTWGE
CCCCCCCEEEEECHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEEEECCEEEEEECCC
RRQGDRLNLEVDLIARYAARLTEARAG
CCCCCEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]