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The map label for this gene is nrdR

Identifier: 170750354

GI number: 170750354

Start: 4210336

End: 4210869

Strand: Direct

Name: nrdR

Synonym: Mrad2831_3957

Alternate gene names: 170750354

Gene position: 4210336-4210869 (Clockwise)

Preceding gene: 170750353

Following gene: 170750355

Centisome position: 69.27

GC content: 73.6

Gene sequence:

>534_bases
ATGCGCTGTCCCTACTGCGGCGGCTCCGAGACCCAGGTGAAGGACTCGCGGCCCTCCGAGGACGGCGCCGCGATCCGGCG
CCGCCGGGTCTGCCCGGACTGCGCCGGCCGCTTCACCACCTTCGAGCGCGTGCAGCTCCGCGAGGTCGTGGTGCTCAAGC
GCTCGGGCAAGCGCGTGCCGTTCGACCGCGACAAGCTCCAGCGCTCCATCGACGTGGCGCTCCGCAAGCGCGCCGTCGAT
CCGGAGCGGATCGAGCGGCTGGTCAGCGGCATCACCCGGCAGCTCGAGAGCGCCGGCGAGCCCGAGGTGACGTCCGAGGC
GATCGGCGAGCTGGTGATGGCGGGGCTGAAGGGCCTCGACGACGTCGCCTACGTGCGCTTCGCCTCGGTCTACAAGAATT
TCCGCGAGGCCCGGGACTTCGAGGAGCTGCTCGGCACCCTGAGCGACGGCATGCCGGTGCCGGCGGCCGCGCCGGAGGCG
GAGGGCGACCCGGAACCCGAGGCGTCGGGGCGCCGCCGCGCCGGGCGTCCATGA

Upstream 100 bases:

>100_bases
TTGAGCGGGGCCGGTCTTCCGGGCCGGCCCGCGGTGGATTAGGAAACGGCCGCGGATCCGACCGGTCCGCGGCCGTTCCC
ATGCCCGAGCATCGAGATCC

Downstream 100 bases:

>100_bases
GCGGCGACGCGAACTTCATGCGCCTCGCCCTGGCGCTGGGCCGCCGCGGGCTCGGCACCACCTGGCCGAACCCGTCGGTC
GGCGCCGTCGTGGTCGAGCC

Product: ATP-cone domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRCPYCGGSETQVKDSRPSEDGAAIRRRRVCPDCAGRFTTFERVQLREVVVLKRSGKRVPFDRDKLQRSIDVALRKRAVD
PERIERLVSGITRQLESAGEPEVTSEAIGELVMAGLKGLDDVAYVRFASVYKNFREARDFEELLGTLSDGMPVPAAAPEA
EGDPEPEASGRRRAGRP

Sequences:

>Translated_177_residues
MRCPYCGGSETQVKDSRPSEDGAAIRRRRVCPDCAGRFTTFERVQLREVVVLKRSGKRVPFDRDKLQRSIDVALRKRAVD
PERIERLVSGITRQLESAGEPEVTSEAIGELVMAGLKGLDDVAYVRFASVYKNFREARDFEELLGTLSDGMPVPAAAPEA
EGDPEPEASGRRRAGRP
>Mature_177_residues
MRCPYCGGSETQVKDSRPSEDGAAIRRRRVCPDCAGRFTTFERVQLREVVVLKRSGKRVPFDRDKLQRSIDVALRKRAVD
PERIERLVSGITRQLESAGEPEVTSEAIGELVMAGLKGLDDVAYVRFASVYKNFREARDFEELLGTLSDGMPVPAAAPEA
EGDPEPEASGRRRAGRP

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=44.9664429530201, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_METRJ (B1LZ89)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756614.1
- GeneID:   6140012
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_3957
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 19634; Mature: 19634

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCGGSETQVKDSRPSEDGAAIRRRRVCPDCAGRFTTFERVQLREVVVLKRSGKRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FDRDKLQRSIDVALRKRAVDPERIERLVSGITRQLESAGEPEVTSEAIGELVMAGLKGLD
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCH
DVAYVRFASVYKNFREARDFEELLGTLSDGMPVPAAAPEAEGDPEPEASGRRRAGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRCPYCGGSETQVKDSRPSEDGAAIRRRRVCPDCAGRFTTFERVQLREVVVLKRSGKRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FDRDKLQRSIDVALRKRAVDPERIERLVSGITRQLESAGEPEVTSEAIGELVMAGLKGLD
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCH
DVAYVRFASVYKNFREARDFEELLGTLSDGMPVPAAAPEAEGDPEPEASGRRRAGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA