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The map label for this gene is bsaA [H]

Identifier: 170750326

GI number: 170750326

Start: 4178596

End: 4179162

Strand: Reverse

Name: bsaA [H]

Synonym: Mrad2831_3929

Alternate gene names: 170750326

Gene position: 4179162-4178596 (Counterclockwise)

Preceding gene: 170750327

Following gene: 170750325

Centisome position: 68.76

GC content: 73.37

Gene sequence:

>567_bases
ATGACGCTGCTGCGCCGCGAGGCCCTGATCCTGCTCGGTGCCGGTCTCGCCGGCGGCGCCCGCGCCGCCGAGCAACCGGC
CGGAACCGCGCGGGCGACGGATTTCGCCTTCGAGACCCCGGAGGGGGCGCCCATGCCGCTCTCCGCCTATGCGGGCAAGC
CGGTCCTCGTGGTCAACACCGCGACGGCCTGCGGCTATGCCGGGCAGCTCGCCGGGCTCCAGACACTCTGGACGCGGTTC
GGCGATCGCGGGCTCGTCGTGCTGGGCGTGCCGTCGCCGGATTTCGGCAACCAAGAGCCGCTGGACGGGCCGGCCATCGC
GGAGGCGGCGCGGAAGAATCACGGCGTCACCTTCCCGCTCACGGCCAAGACCCGGGTGAAGATGCCGGGCGCCCATCCGT
TCTACCGCTGGGCCGCGGCCGAGCGCCCCGCCGAGACGCCGCGCTGGAACTTCCACAAGTACCTGATCGCCCGCGACGGC
ACCCTCGCGGCGGCCTTCGCCACGCAGGTCGAGCCGACCGATCCGCGGGTCATCTCGGGGATCGCCGCCACCCTCGATCA
GGCCTGA

Upstream 100 bases:

>100_bases
CCGGGACTGTACGGTCGACCTGCAGCAGGCGTATCAGTAGGTCGATCCTTTCCCGATCTGGTTCGTTGACGCGCCGGAAC
GTCCGCACCGGAGACCTGCC

Downstream 100 bases:

>100_bases
GCTCTCAGCCGGGCCGGCCTGCGGGATTAAACCGCCGGGCCGACGCGTTCACACCCTATGGCATCGGACAAGAACAAGCG
CCCGGACCTCCTCGACCTGC

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTLLRREALILLGAGLAGGARAAEQPAGTARATDFAFETPEGAPMPLSAYAGKPVLVVNTATACGYAGQLAGLQTLWTRF
GDRGLVVLGVPSPDFGNQEPLDGPAIAEAARKNHGVTFPLTAKTRVKMPGAHPFYRWAAAERPAETPRWNFHKYLIARDG
TLAAAFATQVEPTDPRVISGIAATLDQA

Sequences:

>Translated_188_residues
MTLLRREALILLGAGLAGGARAAEQPAGTARATDFAFETPEGAPMPLSAYAGKPVLVVNTATACGYAGQLAGLQTLWTRF
GDRGLVVLGVPSPDFGNQEPLDGPAIAEAARKNHGVTFPLTAKTRVKMPGAHPFYRWAAAERPAETPRWNFHKYLIARDG
TLAAAFATQVEPTDPRVISGIAATLDQA
>Mature_187_residues
TLLRREALILLGAGLAGGARAAEQPAGTARATDFAFETPEGAPMPLSAYAGKPVLVVNTATACGYAGQLAGLQTLWTRFG
DRGLVVLGVPSPDFGNQEPLDGPAIAEAARKNHGVTFPLTAKTRVKMPGAHPFYRWAAAERPAETPRWNFHKYLIARDGT
LAAAFATQVEPTDPRVISGIAATLDQA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=147, Percent_Identity=36.0544217687075, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI192455698, Length=143, Percent_Identity=34.965034965035, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI75709200, Length=174, Percent_Identity=29.3103448275862, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1788003, Length=168, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17535473, Length=140, Percent_Identity=30.7142857142857, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319721, Length=149, Percent_Identity=30.8724832214765, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322228, Length=137, Percent_Identity=32.1167883211679, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322826, Length=137, Percent_Identity=29.1970802919708, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24656772, Length=146, Percent_Identity=32.1917808219178, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24656767, Length=150, Percent_Identity=32, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24656777, Length=150, Percent_Identity=32, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI85726443, Length=134, Percent_Identity=33.5820895522388, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 19778; Mature: 19647

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLRREALILLGAGLAGGARAAEQPAGTARATDFAFETPEGAPMPLSAYAGKPVLVVNT
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCEEEEEC
ATACGYAGQLAGLQTLWTRFGDRGLVVLGVPSPDFGNQEPLDGPAIAEAARKNHGVTFPL
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
TAKTRVKMPGAHPFYRWAAAERPAETPRWNFHKYLIARDGTLAAAFATQVEPTDPRVISG
CCCEEEECCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHH
IAATLDQA
HHHHHCCC
>Mature Secondary Structure 
TLLRREALILLGAGLAGGARAAEQPAGTARATDFAFETPEGAPMPLSAYAGKPVLVVNT
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCEEEEEC
ATACGYAGQLAGLQTLWTRFGDRGLVVLGVPSPDFGNQEPLDGPAIAEAARKNHGVTFPL
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
TAKTRVKMPGAHPFYRWAAAERPAETPRWNFHKYLIARDGTLAAAFATQVEPTDPRVISG
CCCEEEECCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHH
IAATLDQA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA