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The map label for this gene is engA [H]

Identifier: 170750287

GI number: 170750287

Start: 4136880

End: 4138226

Strand: Direct

Name: engA [H]

Synonym: Mrad2831_3890

Alternate gene names: 170750287

Gene position: 4136880-4138226 (Clockwise)

Preceding gene: 170750286

Following gene: 170750293

Centisome position: 68.07

GC content: 71.94

Gene sequence:

>1347_bases
ATGGATATGCCGACCGTCGCGATCGTCGGGAGGCCGAACGTCGGCAAGTCAACCCTGTTCAACCGCCTCGTGGGCAAGAA
GCTCGCGCTGGTCGACGACCGCCCGGGCGTGACCCGCGACCGGCGCGAGGGCGACGTCGCGTTCGGCGGCCTCGAGTTCC
GGGTGATCGACACCGCCGGCCTGGAAGAGGCCGACGCCGCGAGCCTCACCGGCCGGATGCGCATGCAGACCGAGGCGGCG
ATCCTCGCCGCCGACGTGGTGCTGTTCGTGATCGACGCCCGCGCCGGCGTGCTGCCGGCCGACCAGCCCTTCGCCGAGCT
GGTGCGCCGCGCCGGCTGCCCGGTGATCCTGATCGCCAACAAGGCCGAGGGCGGCGCCGGCCTCGCCGGGGCCTACGAGG
CCTTCACCCTCGGGCTCGGCGACCCGATCCCGTTCTCCGCCGAGCACGGCGAGGGTCTGGGCGAGCTGCACGAGGCGCTC
AAGGGCGCCCTGCCCCAGCGCGACGCGGACGAGGATCCGGACGACGCCCCCGGCGGCCGGGCCCTGAAGGTCGCGATCGT
CGGCCGCCCGAATGCCGGCAAGTCGACCCTGATCAACCGCATGCTCGGCGAGGATCGGCTGCTCGTCGGCCCCGAGGCCG
GCATCACCCGGGACTCGATCTCCCTGGACTGGGAGTGGCGCGGGCGGCGGATCAAGCTGCACGACACGGCCGGGATGCGC
CGCCGCGCCCGGATCGACGACAAGCTGGAGAAGCTCGCGGTCTCGGACGGGTTGCGCGCCGTGCGCTTCGCCGAGGTCGT
GGTGGTGCTCCTCGACGCGACGATCCCGTTCGAGAAGCAGGACCTGACGATCGTCGATCTCGTCGAGAGCGAGGGCCGCG
CCCTGGTGATCGGCCTCAACAAGTGGGACCTGGTCGCCGACCAGCCGGGTCTGCTCAAGCAGCTGCGCGAGGATTGCACG
CGCCTGCTGCCGCAGGTGCGCGGCGTCGCGGTCGTGCCGCTCTCCGGCCTCGCCGGCGACGGCGTCGACAAGCTGATGCA
GGCGGTGGTGCAGGCCGCCGAGGTCTGGGACCGGCGCGTCTCCACCTCGCGCATCAACGACTGGCTGAACGAGGCGACCT
CCCGCAACCCGCCCCCCGCGGTATCGGGGCGGCGGATCAAGATCCGCTACGCCACCCAGGTGAAGAGCCGGCCGCCCCAC
TTCGCGCTGTTCGGCAATCAGCTCAACGCCCTGCCGAAATCCTACACGCGCTACCTCGTGAACGGCCTGCGCGAGGCGTT
CGACCTGCCGGGCACGCCGATCCGCCTGTCCCTGCGGACCTCGCAGAACCCGTTCGACAAGGGCTGA

Upstream 100 bases:

>100_bases
GGGCGGTCCCGTGACGGTGACCGCCGCCAAGCCCGAGCCCGCCGCGCCGCCCCCGCCGATCACGCGCTGATCCTTCGTCC
GGACTGTTTCGAGAACCACC

Downstream 100 bases:

>100_bases
TCCAACCTCCGCTCGTGATGACGGAGGCGATGCGGCAGCCCTGCGCAGCCCTCAGCGCGCCGCGTCGGCGATCCAGTCCA
CCGCGGCCGCCAGCGCGGCG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDMPTVAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDVAFGGLEFRVIDTAGLEEADAASLTGRMRMQTEAA
ILAADVVLFVIDARAGVLPADQPFAELVRRAGCPVILIANKAEGGAGLAGAYEAFTLGLGDPIPFSAEHGEGLGELHEAL
KGALPQRDADEDPDDAPGGRALKVAIVGRPNAGKSTLINRMLGEDRLLVGPEAGITRDSISLDWEWRGRRIKLHDTAGMR
RRARIDDKLEKLAVSDGLRAVRFAEVVVVLLDATIPFEKQDLTIVDLVESEGRALVIGLNKWDLVADQPGLLKQLREDCT
RLLPQVRGVAVVPLSGLAGDGVDKLMQAVVQAAEVWDRRVSTSRINDWLNEATSRNPPPAVSGRRIKIRYATQVKSRPPH
FALFGNQLNALPKSYTRYLVNGLREAFDLPGTPIRLSLRTSQNPFDKG

Sequences:

>Translated_448_residues
MDMPTVAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDVAFGGLEFRVIDTAGLEEADAASLTGRMRMQTEAA
ILAADVVLFVIDARAGVLPADQPFAELVRRAGCPVILIANKAEGGAGLAGAYEAFTLGLGDPIPFSAEHGEGLGELHEAL
KGALPQRDADEDPDDAPGGRALKVAIVGRPNAGKSTLINRMLGEDRLLVGPEAGITRDSISLDWEWRGRRIKLHDTAGMR
RRARIDDKLEKLAVSDGLRAVRFAEVVVVLLDATIPFEKQDLTIVDLVESEGRALVIGLNKWDLVADQPGLLKQLREDCT
RLLPQVRGVAVVPLSGLAGDGVDKLMQAVVQAAEVWDRRVSTSRINDWLNEATSRNPPPAVSGRRIKIRYATQVKSRPPH
FALFGNQLNALPKSYTRYLVNGLREAFDLPGTPIRLSLRTSQNPFDKG
>Mature_448_residues
MDMPTVAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDVAFGGLEFRVIDTAGLEEADAASLTGRMRMQTEAA
ILAADVVLFVIDARAGVLPADQPFAELVRRAGCPVILIANKAEGGAGLAGAYEAFTLGLGDPIPFSAEHGEGLGELHEAL
KGALPQRDADEDPDDAPGGRALKVAIVGRPNAGKSTLINRMLGEDRLLVGPEAGITRDSISLDWEWRGRRIKLHDTAGMR
RRARIDDKLEKLAVSDGLRAVRFAEVVVVLLDATIPFEKQDLTIVDLVESEGRALVIGLNKWDLVADQPGLLKQLREDCT
RLLPQVRGVAVVPLSGLAGDGVDKLMQAVVQAAEVWDRRVSTSRINDWLNEATSRNPPPAVSGRRIKIRYATQVKSRPPH
FALFGNQLNALPKSYTRYLVNGLREAFDLPGTPIRLSLRTSQNPFDKG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=40.7725321888412, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=30.1204819277108, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI2367268, Length=164, Percent_Identity=37.8048780487805, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=136, Percent_Identity=30.8823529411765, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48549; Mature: 48549

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMPTVAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDVAFGGLEFRVIDTAG
CCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEECCEEEEEEECCC
LEEADAASLTGRMRMQTEAAILAADVVLFVIDARAGVLPADQPFAELVRRAGCPVILIAN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEE
KAEGGAGLAGAYEAFTLGLGDPIPFSAEHGEGLGELHEALKGALPQRDADEDPDDAPGGR
CCCCCCCCCCHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ALKVAIVGRPNAGKSTLINRMLGEDRLLVGPEAGITRDSISLDWEWRGRRIKLHDTAGMR
EEEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCEEEEECCCCCH
RRARIDDKLEKLAVSDGLRAVRFAEVVVVLLDATIPFEKQDLTIVDLVESEGRALVIGLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECC
KWDLVADQPGLLKQLREDCTRLLPQVRGVAVVPLSGLAGDGVDKLMQAVVQAAEVWDRRV
CCCEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
STSRINDWLNEATSRNPPPAVSGRRIKIRYATQVKSRPPHFALFGNQLNALPKSYTRYLV
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHH
NGLREAFDLPGTPIRLSLRTSQNPFDKG
HHHHHHHCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MDMPTVAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDVAFGGLEFRVIDTAG
CCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEECCEEEEEEECCC
LEEADAASLTGRMRMQTEAAILAADVVLFVIDARAGVLPADQPFAELVRRAGCPVILIAN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEE
KAEGGAGLAGAYEAFTLGLGDPIPFSAEHGEGLGELHEALKGALPQRDADEDPDDAPGGR
CCCCCCCCCCHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ALKVAIVGRPNAGKSTLINRMLGEDRLLVGPEAGITRDSISLDWEWRGRRIKLHDTAGMR
EEEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCEEEEECCCCCH
RRARIDDKLEKLAVSDGLRAVRFAEVVVVLLDATIPFEKQDLTIVDLVESEGRALVIGLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECC
KWDLVADQPGLLKQLREDCTRLLPQVRGVAVVPLSGLAGDGVDKLMQAVVQAAEVWDRRV
CCCEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
STSRINDWLNEATSRNPPPAVSGRRIKIRYATQVKSRPPHFALFGNQLNALPKSYTRYLV
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHH
NGLREAFDLPGTPIRLSLRTSQNPFDKG
HHHHHHHCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA