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The map label for this gene is alr [H]

Identifier: 170750293

GI number: 170750293

Start: 4143230

End: 4144324

Strand: Direct

Name: alr [H]

Synonym: Mrad2831_3896

Alternate gene names: 170750293

Gene position: 4143230-4144324 (Clockwise)

Preceding gene: 170750287

Following gene: 170750294

Centisome position: 68.17

GC content: 74.79

Gene sequence:

>1095_bases
GTGGCCGAGACCGGACCTGTGACGGAGATCGGCGCTCACGGCGCCCGGCTCACGATCGACCTCGGAGCGATCGCCGCCAA
CTGGCGGATCCTGGCCGCCCGCGGCGCCGGCGCCGACTGCGCCGCCGTGGTGAAGGCCGACGCCTACGGTTGCGGCATCG
GCCGGGTCGGACCGGCCCTGTGGGCCGCGGGCTGCCGGACCTTCTTCGTCGCGCACCTGTCCGAGGGCGTCGCCGCCCGG
GCCGCCCTGCCGGAGGCCGCGATCTACGTGCTGAACGGCCTGCCCTTGGGCGCCGCGGCGGCCTTCGCGGCCCACGGGCT
GCGCCCGGTGCTCGGCAGCGCCGAGGAGCTGTCGGACTGGGCGGCGTTCGCGGGGAACCGCCCGCCCGCGGCGCTCCACG
TCGATACCGGCATGAACCGGCTCGGCCTGTCGGTGCCCGAGGCGCTGGATCTCGCCGGGGACGCGCGGATCGCGGAGGCC
GGGATCGACCTCCTCCTCAGCCACTTCGTCAGCGCCGAGACGCCGGACGACCCGGTCAACGCCCGGCAGATCGCCGATTT
CGCTCGGGTTCGGGCCGCCTATCCCGGACTCCGGGCCTCGCTGGCGAACTCGTCGGGAATCTTCCTCGACGGGGCCCGGC
ACGACCTCCTGCGGCCGGGCTACGCCCTGTTCGGCGGCAACCCGACGCCGGGCGCCGCGAACCCGATGCGGCCGGTGGTG
CGGCTGGAGGCGACGATCGCGCAGGTGCGCGGCGTCGCGGCCGGCGCCACCGCGGGCTATAACGGCCGCTGGACCGCCAC
CGCGCCCAGCCGCCTGGCGACGCTCTCGCTCGGTTACGCCGACGGCTTCCCCCGGTCGATCAGCGGGCGCGGCCAGGCGC
TGGTCGGGGGCGTTCCGTGCCCGATCCTGGGCTCCGTCTCGATGGACCTGATCATCCTCGACGTCACGGCGGCGCCCGCG
GCCCGGCGCGGCGCCGCCGCGGTACTGATCGGCGACCGCCTCGACATCGACACGGTCGGTCGCGCCGCCGGCACAATCGG
CTACGAGATCCTCACGGGACTGGGTTCTCGTTATGTTCGAACCTATGTAGGGTAG

Upstream 100 bases:

>100_bases
TGTTAACGACGGCCCGTGCTGCCCCCGGGCGCCGTCCGGATGCTATGGGTCCGGCCTGTGCTTCCGCGACCCCGGTGGCG
AACAGATGGAGGCGGTCTGC

Downstream 100 bases:

>100_bases
CTCCCTCCCCTGACCGGAAGGCCGGACGGCCGGCGCGCGGACTCGAATGGCCAAGATCCACCAGACCTTCGTCTGCCAGT
CCTGCGGGGCGGTCTACAAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MAETGPVTEIGAHGARLTIDLGAIAANWRILAARGAGADCAAVVKADAYGCGIGRVGPALWAAGCRTFFVAHLSEGVAAR
AALPEAAIYVLNGLPLGAAAAFAAHGLRPVLGSAEELSDWAAFAGNRPPAALHVDTGMNRLGLSVPEALDLAGDARIAEA
GIDLLLSHFVSAETPDDPVNARQIADFARVRAAYPGLRASLANSSGIFLDGARHDLLRPGYALFGGNPTPGAANPMRPVV
RLEATIAQVRGVAAGATAGYNGRWTATAPSRLATLSLGYADGFPRSISGRGQALVGGVPCPILGSVSMDLIILDVTAAPA
ARRGAAAVLIGDRLDIDTVGRAAGTIGYEILTGLGSRYVRTYVG

Sequences:

>Translated_364_residues
MAETGPVTEIGAHGARLTIDLGAIAANWRILAARGAGADCAAVVKADAYGCGIGRVGPALWAAGCRTFFVAHLSEGVAAR
AALPEAAIYVLNGLPLGAAAAFAAHGLRPVLGSAEELSDWAAFAGNRPPAALHVDTGMNRLGLSVPEALDLAGDARIAEA
GIDLLLSHFVSAETPDDPVNARQIADFARVRAAYPGLRASLANSSGIFLDGARHDLLRPGYALFGGNPTPGAANPMRPVV
RLEATIAQVRGVAAGATAGYNGRWTATAPSRLATLSLGYADGFPRSISGRGQALVGGVPCPILGSVSMDLIILDVTAAPA
ARRGAAAVLIGDRLDIDTVGRAAGTIGYEILTGLGSRYVRTYVG
>Mature_363_residues
AETGPVTEIGAHGARLTIDLGAIAANWRILAARGAGADCAAVVKADAYGCGIGRVGPALWAAGCRTFFVAHLSEGVAARA
ALPEAAIYVLNGLPLGAAAAFAAHGLRPVLGSAEELSDWAAFAGNRPPAALHVDTGMNRLGLSVPEALDLAGDARIAEAG
IDLLLSHFVSAETPDDPVNARQIADFARVRAAYPGLRASLANSSGIFLDGARHDLLRPGYALFGGNPTPGAANPMRPVVR
LEATIAQVRGVAAGATAGYNGRWTATAPSRLATLSLGYADGFPRSISGRGQALVGGVPCPILGSVSMDLIILDVTAAPAA
RRGAAAVLIGDRLDIDTVGRAAGTIGYEILTGLGSRYVRTYVG

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=34.5609065155807, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790487, Length=366, Percent_Identity=29.7814207650273, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 36943; Mature: 36811

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETGPVTEIGAHGARLTIDLGAIAANWRILAARGAGADCAAVVKADAYGCGIGRVGPAL
CCCCCCCHHHCCCCCEEEEEECEEEECCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHH
WAAGCRTFFVAHLSEGVAARAALPEAAIYVLNGLPLGAAAAFAAHGLRPVLGSAEELSDW
HHHHHHHHHHHHHHCCHHHHHCCCHHEEEEECCCCHHHHHHHHHCCCHHHHCCHHHHHHH
AAFAGNRPPAALHVDTGMNRLGLSVPEALDLAGDARIAEAGIDLLLSHFVSAETPDDPVN
HHHCCCCCCEEEEECCCCHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ARQIADFARVRAAYPGLRASLANSSGIFLDGARHDLLRPGYALFGGNPTPGAANPMRPVV
HHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCHHHHCCCCEEEECCCCCCCCCCCCCHHH
RLEATIAQVRGVAAGATAGYNGRWTATAPSRLATLSLGYADGFPRSISGRGQALVGGVPC
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCC
PILGSVSMDLIILDVTAAPAARRGAAAVLIGDRLDIDTVGRAAGTIGYEILTGLGSRYVR
CCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TYVG
HHCC
>Mature Secondary Structure 
AETGPVTEIGAHGARLTIDLGAIAANWRILAARGAGADCAAVVKADAYGCGIGRVGPAL
CCCCCCHHHCCCCCEEEEEECEEEECCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHH
WAAGCRTFFVAHLSEGVAARAALPEAAIYVLNGLPLGAAAAFAAHGLRPVLGSAEELSDW
HHHHHHHHHHHHHHCCHHHHHCCCHHEEEEECCCCHHHHHHHHHCCCHHHHCCHHHHHHH
AAFAGNRPPAALHVDTGMNRLGLSVPEALDLAGDARIAEAGIDLLLSHFVSAETPDDPVN
HHHCCCCCCEEEEECCCCHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ARQIADFARVRAAYPGLRASLANSSGIFLDGARHDLLRPGYALFGGNPTPGAANPMRPVV
HHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCHHHHCCCCEEEECCCCCCCCCCCCCHHH
RLEATIAQVRGVAAGATAGYNGRWTATAPSRLATLSLGYADGFPRSISGRGQALVGGVPC
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCC
PILGSVSMDLIILDVTAAPAARRGAAAVLIGDRLDIDTVGRAAGTIGYEILTGLGSRYVR
CCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TYVG
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA